iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062469

Ensembl Protein ID

ENSMODP00000019552.2

UniProt Accession

F7EI58; F7EI58_MONDO

Protein Name

Coronin

Gene Name

CORO1A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000015665.2	ENSMODT00000019901.2	ENSMODP00000019552.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.30e-20	70.4	79	116

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDlrtgvl 35
           gHt++v ++a+   +d+ ++sGs D+ ++vW++ +g l
   Q: 79   GHTAPVLDIAWcphNDNVIASGSEDCMVMVWEIPDGGL 116
           8***********9877****************998875 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MSRQVVRSSK FRHVFGQPAK ADQCYEDVRV SQTTWDSGFC AVNPKFMALI CEASGGGAFL 60
VLPLTKTGRV DKNVPTVCGH TAPVLDIAWC PHNDNVIASG SEDCMVMVWE IPDGGLTLPL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGCCGAC AGGTGGTTCG AAGCAGCAAG TTCCGACACG TATTTGGACA ACCAGCCAAG 60
GCTGACCAGT GTTATGAGGA CGTTAGAGTC TCCCAGACCA CTTGGGACAG TGGTTTCTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR024977--Apc4_WD40_dom
IPR029508--CORO1A
IPR015505--Coronin
IPR015048--DUF1899
IPR015049--Trimer_CC
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF08953--DUF1899
PF08954--Trimer_CC
PF00400--WD40

SMART

SM01166--DUF1899
SM00320--WD40

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0005884--C:actin filament
GO:0030424--C:axon
GO:0005911--C:cell-cell junction
GO:0030864--C:cortical actin cytoskeleton
GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0070062--C:extracellular exosome
GO:0001772--C:immunological synapse
GO:0030027--C:lamellipodium
GO:0001891--C:phagocytic cup
GO:0045335--C:phagocytic vesicle
GO:0043234--C:protein complex
GO:0051015--F:actin filament binding
GO:0003723--F:RNA binding
GO:0030036--P:actin cytoskeleton organization
GO:0007015--P:actin filament organization
GO:0006816--P:calcium ion transport
GO:0031589--P:cell-substrate adhesion
GO:0071353--P:cellular response to interleukin-4
GO:0061502--P:early endosome to recycling endosome transport
GO:0048873--P:homeostasis of number of cells within a tissue
GO:0030595--P:leukocyte chemotaxis
GO:0043320--P:natural killer cell degranulation
GO:0051126--P:negative regulation of actin nucleation
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0031339--P:negative regulation of vesicle fusion
GO:0038180--P:nerve growth factor signaling pathway
GO:0001845--P:phagolysosome assembly
GO:0050918--P:positive chemotaxis
GO:0030335--P:positive regulation of cell migration
GO:0042102--P:positive regulation of T cell proliferation
GO:0008360--P:regulation of cell shape
GO:0051279--P:regulation of release of sequestered calcium ion into cytosol
GO:0043029--P:T cell homeostasis
GO:0032796--P:uropod organization

KEGG

mdo:100014449

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002012	Ailuropoda melanoleuca	90.39	0.00e+00	872.00
IUUC-Aca-005048	Anolis carolinensis	68.84	0.00e+00	685.00
IUUC-Ago-007901	Ashbya gossypii	41.46	2.00e-89	323.00
IUUC-Acl-008280	Aspergillus clavatus	42.75	8.00e-98	351.00
IUUC-Afl-008393	Aspergillus flavus	42.86	3.00e-97	349.00
IUUC-Afu-008865	Aspergillus fumigatus	41.05	5.00e-94	338.00
IUUC-Ani-009155	Aspergillus nidulans	42.37	4.00e-97	348.00
IUUC-Ang-009523	Aspergillus niger	40.93	7.00e-88	318.00
IUUC-Aor-010049	Aspergillus oryzae	42.18	4.00e-93	335.00
IUUC-Ate-010368	Aspergillus terreus	42.93	7.00e-93	334.00
IUUC-Ame-011101	Astyanax mexicanus	69.48	0.00e+00	691.00
IUUC-Bgr-011990	Blumeria graminis	41.87	2.00e-97	349.00
IUUC-Bta-013168	Bos taurus	91.05	0.00e+00	879.00
IUUC-Bci-013935	Botrytis cinerea	42.82	5.00e-100	358.00
IUUC-Cja-019660	Callithrix jacchus	90.39	0.00e+00	880.00
IUUC-Cfa-020938	Canis familiaris	90.83	0.00e+00	877.00
IUUC-Cpo-022056	Cavia porcellus	89.30	0.00e+00	871.00
IUUC-Csa-023193	Chlorocebus sabaeus	90.17	0.00e+00	874.00
IUUC-Cgl-026456	Colletotrichum gloeosporioides	41.73	4.00e-94	338.00
IUUC-Cne-026773	Cryptococcus neoformans	39.42	7.00e-88	318.00
IUUC-Dre-028167	Danio rerio	68.20	0.00e+00	672.00
IUUC-Dno-029363	Dasypus novemcinctus	90.61	0.00e+00	877.00
IUUC-Dor-030426	Dipodomys ordii	90.61	0.00e+00	875.00
IUUC-Dse-031378	Dothistroma septosporum	40.53	4.00e-88	319.00
IUUC-Eca-034229	Equus caballus	89.52	0.00e+00	869.00
IUUC-Eeu-034499	Erinaceus europaeus	87.56	0.00e+00	744.00
IUUC-Fca-036472	Felis catus	88.86	0.00e+00	863.00
IUUC-Fox-037737	Fusarium oxysporum	42.22	6.00e-90	324.00
IUUC-Fso-038184	Fusarium solani	43.21	2.00e-98	353.00
IUUC-Gmo-039519	Gadus morhua	66.24	0.00e+00	665.00
IUUC-Ggr-039956	Gaeumannomyces graminis	41.58	1.00e-94	340.00
IUUC-Ggo-045162	Gorilla gorilla	89.96	0.00e+00	873.00
IUUC-Hsa-046874	Homo sapiens	89.96	0.00e+00	873.00
IUUC-Itr-048911	Ictidomys tridecemlineatus	91.48	0.00e+00	883.00
IUUC-Lch-050582	Latimeria chalumnae	66.60	0.00e+00	691.00
IUUC-Lma-053160	Leptosphaeria maculans	43.35	4.00e-96	345.00
IUUC-Laf-053427	Loxodonta africana	90.17	0.00e+00	863.00
IUUC-Mcc-055750	Macaca mulatta	92.27	0.00e+00	832.00
IUUC-Meu-056083	Macropus eugenii	95.01	0.00e+00	899.00
IUUC-Mor-056978	Magnaporthe oryzae	43.17	3.00e-97	348.00
IUUC-Mpo-057410	Magnaporthe poae	42.33	4.00e-90	325.00
IUUC-Mla-058883	Melampsora laricipopulina	44.55	1.00e-88	320.00
IUUC-Mvi-060569	Microbotryum violaceum	40.74	2.00e-88	319.00
IUUC-Mmr-060858	Microcebus murinus	90.17	0.00e+00	876.00
IUUC-Mmu-063583	Mus musculus	89.96	0.00e+00	871.00
IUUC-Mpu-066451	Mustela putorius furo	91.16	0.00e+00	850.00
IUUC-Mlu-066978	Myotis lucifugus	89.52	0.00e+00	870.00
IUUC-Nfi-068476	Neosartorya fischeri	42.26	8.00e-97	347.00
IUUC-Ncr-068781	Neurospora crassa	41.75	5.00e-98	351.00
IUUC-Nle-069815	Nomascus leucogenys	90.39	0.00e+00	875.00
IUUC-Opr-070911	Ochotona princeps	89.74	0.00e+00	857.00
IUUC-Ont-072391	Oreochromis niloticus	69.28	0.00e+00	687.00
IUUC-Ocu-074429	Oryctolagus cuniculus	81.44	0.00e+00	758.00
IUUC-Oga-089072	Otolemur garnettii	90.00	0.00e+00	873.00
IUUC-Oar-089676	Ovis aries	90.61	0.00e+00	876.00
IUUC-Ptr-091647	Pan troglodytes	89.96	0.00e+00	874.00
IUUC-Pan-092672	Papio anubis	90.17	0.00e+00	874.00
IUUC-Pno-094994	Phaeosphaeria nodorum	43.95	1.00e-96	347.00
IUUC-Pab-098348	Pongo abelii	85.15	0.00e+00	809.00
IUUC-Pva-102668	Pteropus vampyrus	90.17	0.00e+00	873.00
IUUC-Pgr-103354	Puccinia graminis	43.21	1.00e-93	337.00
IUUC-Ptt-103735	Puccinia triticina	35.94	5.00e-72	265.00
IUUC-Pte-104194	Pyrenophora teres	42.22	2.00e-94	340.00
IUUC-Pyt-104437	Pyrenophora triticirepentis	42.22	2.00e-94	340.00
IUUC-Rno-105604	Rattus norvegicus	89.96	0.00e+00	867.00
IUUC-Sce-106378	Saccharomyces cerevisiae	41.11	5.00e-90	325.00
IUUC-Sha-107210	Sarcophilus harrisii	95.66	0.00e+00	920.00
IUUC-Sja-107992	Schizosaccharomyces japonicus	42.96	1.00e-98	353.00
IUUC-Spo-108364	Schizosaccharomyces pombe	43.28	8.00e-98	351.00
IUUC-Sar-113292	Sorex araneus	93.78	0.00e+00	726.00
IUUC-Sre-114911	Sporisorium reilianum	39.52	3.00e-80	292.00
IUUC-Tru-117655	Takifugu rubripes	67.80	0.00e+00	683.00
IUUC-Tre-122159	Trichoderma reesei	41.45	3.00e-95	342.00
IUUC-Tvi-122480	Trichoderma virens	42.82	4.00e-96	345.00
IUUC-Tme-126924	Tuber melanosporum	42.36	3.00e-95	342.00
IUUC-Tbe-128025	Tupaia belangeri	93.31	2.00e-149	520.00
IUUC-Ttr-128689	Tursiops truncatus	89.74	0.00e+00	868.00
IUUC-Uma-129489	Ustilago maydis	39.23	3.00e-85	309.00
IUUC-Vda-129792	Verticillium dahliae	40.59	6.00e-93	335.00
IUUC-Yli-134440	Yarrowia lipolytica	42.43	2.00e-92	333.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence