iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-117595

UUCD1 version

UUC-TaR-00153

Ensembl Protein ID

ENSTRUP00000008130.1

UniProt Accession

H2S6V8; H2S6V8_TAKRU

Protein Name

Uncharacterized protein

Gene Name

wdr37 (1 of many); wdr37

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000003466.1	ENSTRUT00000008178.1	ENSTRUP00000008130.1
ENSTRUG00000003466.1	ENSTRUT00000008179.1	ENSTRUP00000008131.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.00e-24	83.8	367	398
UBD/Beta-Prp	2.80e-46	159.3	278	488

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sdtllvsGsdDgtikvWDlr 31
           gHtd vt+  f  ++ +vsGsdD t+kvWDl+
   Q: 367  GHTDTVTSAVFtVGDNVVSGSDDRTVKVWDLK 398
           8*******99*733669*************96 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkc..vhtl 90
           tl++ h++v+ + ++  ++++++t+s+d+   ++dv+t  l++sl gh++e t ++ +p++ + vt+s+D t ++wd++++++  v ++
   Q: 278  TLRS-HQGVVIAADWLVGGKQVVTASWDRAANLYDVETSELVHSLTGHDQELTHCCTNPTQRLVVTSSRDTTFRLWDFRDPSIhsVNVF 365
           4444.5556666999999*************************************************************665422889* PP
   S: 91   kghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrtlt 176
           +gh+d+v+s  f   gd +vsGs+drt++vwdl++          +d++vn ++v+ ++++++  +++r+vrl+d    + ++l r  +
   Q: 366  QGHTDTVTSAVFTV-GDNVVSGSDDRTVKVWDLKNMRSPI-ATIRTDSAVNRISVSVNQKIIALPHDNRQVRLFDTsgvRLARLPRSNR 452
           *********99999.********************99987.77788999**************************97777778888888 PP
   S: 177  gghtdsvyslsfdsng..kelvsgsldgtvklwdlq 210
           +gh ++v + ++ ++     l +++ d++ + w++ 
   Q: 453  QGHRRMVCCSTWCEDNpsCNLFTCGFDRQAIGWNIN 488
           88*********87777457789*********99986 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MPVETASSAA ARQAKQKRKS HSLSIRRTNS TEQERSGPQR ELLESQDSKL PLSLRSNLMD 60
LFSQIEREFE NLYIENLELR REIDSLNDRL AADGQTLEGA DLAKGALKSK ASHSTSQLSQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCCGTGG AGACGGCGAG CAGTGCCGCT GCTCGCCAAG CCAAGCAGAA GAGGAAGTCC 60
CACAGCTTGT CCATCCGCAG GACCAACAGC ACGGAGCAGG AGCGCTCCGG GCCGCAGAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0070545--C:PeBoW complex
GO:0030687--C:preribosome, large subunit precursor
GO:0000460--P:maturation of 5.8S rRNA
GO:0000470--P:maturation of LSU-rRNA

KEGG

tru:101077523

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001249	Ailuropoda melanoleuca	82.86	0.00e+00	849.00
IUUC-Apl-003647	Anas platyrhynchos	84.88	0.00e+00	857.00
IUUC-Aca-004759	Anolis carolinensis	84.68	0.00e+00	857.00
IUUC-Ame-011103	Astyanax mexicanus	57.94	1.00e-146	513.00
IUUC-Bta-012718	Bos taurus	83.06	0.00e+00	846.00
IUUC-Cja-019492	Callithrix jacchus	84.68	0.00e+00	864.00
IUUC-Cfa-020199	Canis familiaris	82.66	0.00e+00	854.00
IUUC-Cpo-022500	Cavia porcellus	77.82	0.00e+00	801.00
IUUC-Csa-023567	Chlorocebus sabaeus	84.48	0.00e+00	862.00
IUUC-Cho-025071	Choloepus hoffmanni	58.06	5.00e-153	534.00
IUUC-Csv-026042	Ciona savignyi	46.17	2.00e-108	386.00
IUUC-Dre-028214	Danio rerio	87.90	0.00e+00	893.00
IUUC-Dno-029826	Dasypus novemcinctus	86.02	0.00e+00	741.00
IUUC-Dor-030967	Dipodomys ordii	82.34	0.00e+00	766.00
IUUC-Ete-032452	Echinops telfairi	80.44	0.00e+00	827.00
IUUC-Eca-033278	Equus caballus	83.47	0.00e+00	858.00
IUUC-Eeu-034592	Erinaceus europaeus	70.97	0.00e+00	698.00
IUUC-Fca-036431	Felis catus	83.30	0.00e+00	855.00
IUUC-Fal-037149	Ficedula albicollis	84.68	0.00e+00	859.00
IUUC-Gga-041099	Gallus gallus	85.08	0.00e+00	860.00
IUUC-Gac-042374	Gasterosteus aculeatus	92.40	0.00e+00	891.00
IUUC-Ggo-044683	Gorilla gorilla	78.02	0.00e+00	788.00
IUUC-Hsa-046658	Homo sapiens	83.06	0.00e+00	857.00
IUUC-Itr-048870	Ictidomys tridecemlineatus	85.05	0.00e+00	806.00
IUUC-Lch-050571	Latimeria chalumnae	80.46	0.00e+00	826.00
IUUC-Loc-052652	Lepisosteus oculatus	82.82	0.00e+00	848.00
IUUC-Laf-053712	Loxodonta africana	83.17	0.00e+00	850.00
IUUC-Mcc-055521	Macaca mulatta	84.48	0.00e+00	862.00
IUUC-Meu-056324	Macropus eugenii	81.65	0.00e+00	802.00
IUUC-Mga-060114	Meleagris gallopavo	85.28	0.00e+00	867.00
IUUC-Mmr-061176	Microcebus murinus	83.47	0.00e+00	853.00
IUUC-Mdo-061888	Monodelphis domestica	86.09	0.00e+00	838.00
IUUC-Mmu-063977	Mus musculus	84.48	0.00e+00	868.00
IUUC-Mpu-066220	Mustela putorius furo	69.79	8.00e-148	516.00
IUUC-Mlu-068155	Myotis lucifugus	84.48	0.00e+00	867.00
IUUC-Nle-069964	Nomascus leucogenys	84.07	0.00e+00	859.00
IUUC-Opr-070925	Ochotona princeps	78.26	4.00e-123	434.00
IUUC-Ont-071317	Oreochromis niloticus	93.75	0.00e+00	890.00
IUUC-Oan-072952	Ornithorhynchus anatinus	85.08	0.00e+00	862.00
IUUC-Ocu-073913	Oryctolagus cuniculus	84.07	0.00e+00	866.00
IUUC-Ola-087024	Oryzias latipes	89.94	0.00e+00	915.00
IUUC-Oga-087945	Otolemur garnettii	84.07	0.00e+00	865.00
IUUC-Oar-089854	Ovis aries	83.27	0.00e+00	840.00
IUUC-Ptr-091486	Pan troglodytes	83.27	0.00e+00	858.00
IUUC-Pan-091738	Papio anubis	84.48	0.00e+00	862.00
IUUC-Psi-093953	Pelodiscus sinensis	83.87	0.00e+00	854.00
IUUC-Pma-094560	Petromyzon marinus	70.69	0.00e+00	740.00
IUUC-Pfo-097222	Poecilia formosa	91.33	0.00e+00	885.00
IUUC-Pab-098778	Pongo abelii	78.83	0.00e+00	801.00
IUUC-Pca-100852	Procavia capensis	79.23	0.00e+00	801.00
IUUC-Pva-103130	Pteropus vampyrus	81.40	4.00e-117	414.00
IUUC-Rno-105848	Rattus norvegicus	77.42	0.00e+00	764.00
IUUC-Sha-106750	Sarcophilus harrisii	85.69	0.00e+00	864.00
IUUC-Sar-113749	Sorex araneus	76.01	0.00e+00	769.00
IUUC-Ssc-115691	Sus scrofa	82.66	0.00e+00	827.00
IUUC-Tgu-117365	Taeniopygia guttata	84.68	0.00e+00	817.00
IUUC-Tsy-118973	Tarsius syrichta	65.11	1.00e-127	449.00
IUUC-Tni-120545	Tetraodon nigroviridis	94.58	0.00e+00	947.00
IUUC-Tbe-127976	Tupaia belangeri	62.50	1.00e-169	589.00
IUUC-Ttr-128472	Tursiops truncatus	80.85	0.00e+00	816.00
IUUC-Xtr-132621	Xenopus tropicalis	84.48	0.00e+00	825.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence