iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	TRANSFAC	RAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	8.30e-12	45.7	24	85

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           +D+++vv+g+ f+ahk+vLaa+S++F+ lf     +  +k+ v+++   +  + ++l+F+Yt kl ++
   Q: 24   CDCTFVVDGVDFKAHKAVLAACSEYFKMLFV----D--QKDVVHLDISNAAGLGQVLEFMYTAKLHLS 85
           9*****************************2....2..26788888678999************9875 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MDFPQHSQRV LEQLNQQRQM GLLCDCTFVV DGVDFKAHKA VLAACSEYFK MLFVDQKDVV 60
HLDISNAAGL GQVLEFMYTA KLHLSPENVD DVLAVASFLQ MQDIITACHT LKSLAEPTST 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCGGACGAG CGCTGCGCCA GCGACGGAAG TCGCAGCCGG GAAGCCAGCG AGGTCCGTTC 60
CGCCCGACTC TAACATGGCG GCGCCCTTTG TCTACTGTGA AGCGCTGCCC CCGGCCTTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR023413--GFP-like
IPR004039--Rubredoxin-type_fold
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0005634--C:nucleus
GO:0046872--F:metal ion binding
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077--F:transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0007398--P:ectoderm development
GO:0001702--P:gastrulation with mouth forming second
GO:1903955--P:positive regulation of protein targeting to mitochondrion
GO:1903146--P:regulation of mitophagy

KEGG

rno:313666

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002207	Ailuropoda melanoleuca	75.06	0.00e+00	973.00
IUUC-Apl-003789	Anas platyrhynchos	73.67	0.00e+00	1007.00
IUUC-Bta-012571	Bos taurus	96.88	0.00e+00	996.00
IUUC-Cja-018730	Callithrix jacchus	87.15	0.00e+00	1326.00
IUUC-Cfa-020463	Canis familiaris	89.78	0.00e+00	1221.00
IUUC-Cpo-022120	Cavia porcellus	89.74	0.00e+00	1290.00
IUUC-Csa-024263	Chlorocebus sabaeus	78.53	9.00e-82	296.00
IUUC-Dre-027469	Danio rerio	78.19	0.00e+00	813.00
IUUC-Dno-029237	Dasypus novemcinctus	88.90	0.00e+00	1254.00
IUUC-Ete-033053	Echinops telfairi	80.76	0.00e+00	1172.00
IUUC-Eca-033861	Equus caballus	89.66	0.00e+00	1282.00
IUUC-Fca-036528	Felis catus	81.79	4.00e-133	468.00
IUUC-Fal-037166	Ficedula albicollis	90.37	0.00e+00	891.00
IUUC-Gmo-038904	Gadus morhua	75.05	0.00e+00	802.00
IUUC-Gga-040721	Gallus gallus	90.06	0.00e+00	907.00
IUUC-Gac-041298	Gasterosteus aculeatus	74.49	0.00e+00	786.00
IUUC-Ggo-045394	Gorilla gorilla	87.10	0.00e+00	1320.00
IUUC-Hsa-046073	Homo sapiens	87.39	0.00e+00	1322.00
IUUC-Itr-048299	Ictidomys tridecemlineatus	91.51	0.00e+00	1341.00
IUUC-Lch-050218	Latimeria chalumnae	72.35	0.00e+00	725.00
IUUC-Loc-052153	Lepisosteus oculatus	76.55	0.00e+00	782.00
IUUC-Laf-053829	Loxodonta africana	89.89	0.00e+00	1320.00
IUUC-Mcc-055270	Macaca mulatta	76.56	0.00e+00	1090.00
IUUC-Meu-056271	Macropus eugenii	88.17	0.00e+00	976.00
IUUC-Mga-059305	Meleagris gallopavo	68.65	0.00e+00	983.00
IUUC-Mmr-060760	Microcebus murinus	91.07	0.00e+00	1331.00
IUUC-Mdo-062280	Monodelphis domestica	78.38	0.00e+00	1185.00
IUUC-Mmu-064100	Mus musculus	96.75	0.00e+00	1454.00
IUUC-Mpu-066286	Mustela putorius furo	79.50	2.00e-173	602.00
IUUC-Mlu-067394	Myotis lucifugus	89.03	0.00e+00	1259.00
IUUC-Nle-069713	Nomascus leucogenys	88.15	0.00e+00	1157.00
IUUC-Opr-071195	Ochotona princeps	86.65	0.00e+00	1266.00
IUUC-Ont-071808	Oreochromis niloticus	79.37	0.00e+00	820.00
IUUC-Oan-072892	Ornithorhynchus anatinus	89.25	0.00e+00	912.00
IUUC-Ocu-074812	Oryctolagus cuniculus	90.15	0.00e+00	1296.00
IUUC-Oga-088345	Otolemur garnettii	90.70	0.00e+00	1335.00
IUUC-Oar-089992	Ovis aries	97.73	3.00e-113	402.00
IUUC-Ptr-091414	Pan troglodytes	90.21	0.00e+00	1344.00
IUUC-Pan-091888	Papio anubis	90.46	0.00e+00	1352.00
IUUC-Psi-094055	Pelodiscus sinensis	84.33	0.00e+00	854.00
IUUC-Pfo-096787	Poecilia formosa	79.42	0.00e+00	795.00
IUUC-Pab-098341	Pongo abelii	87.35	0.00e+00	1326.00
IUUC-Pca-100832	Procavia capensis	89.40	0.00e+00	1201.00
IUUC-Pva-102905	Pteropus vampyrus	89.00	0.00e+00	1226.00
IUUC-Sha-107460	Sarcophilus harrisii	63.68	0.00e+00	891.00
IUUC-Sar-113442	Sorex araneus	82.32	0.00e+00	1096.00
IUUC-Ssc-115342	Sus scrofa	82.78	0.00e+00	1137.00
IUUC-Tgu-117348	Taeniopygia guttata	91.74	0.00e+00	830.00
IUUC-Tru-118668	Takifugu rubripes	73.99	0.00e+00	803.00
IUUC-Tni-120159	Tetraodon nigroviridis	73.94	0.00e+00	793.00
IUUC-Tbe-127424	Tupaia belangeri	75.68	4.00e-108	385.00
IUUC-Ttr-128620	Tursiops truncatus	88.01	0.00e+00	1102.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence