iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ggo-044932

Ensembl Protein ID

ENSGGOP00000000151.2

UniProt Accession

G3QD46; G3QD46_GORGO

Protein Name

Uncharacterized protein

Gene Name

EFCAB8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000000152.2	ENSGGOT00000000153.2	ENSGGOP00000000151.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.70e-18	65.0	371	397
UBD/Beta-Prp	9.00e-41	140.4	372	593

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 5    svtclaf.sd.tllvsGsdDgtikvWD 29
           ++ c+++ +d ++lv+G++D  i++W+
   Q: 371  GILCFDYcPDrNFLVTGGYDAFIRLWN 397
           5889999*******************9 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkl.lrslsgheaevtavkfspdgk.ilvtgseDrtikvwdlstgkcvhtlkgh.....e 94
           i c ++ pd+++l+tg++d+ i++w+ +  k  ++ ++gh+  vt +  +++ + il+++s+D++i+vwd+ ++ c++++ g+     +
   Q: 372  ILCFDYCPDRNFLVTGGYDAFIRLWNPFVSKRpVWLMKGHQTSVTHILVDSRNNsILISVSKDKNIRVWDMLDYICLQSFCGKffalgN 460
           33566677777777777777777777776666455567777777777777766667777777777777777777777777765111113 PP
   S: 95   dsvlslsfspsg.dklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtl..tggh 179
             ++s  f++++   + s+ +  +++ + le +  +++ ++ ++ +  c+v+ ++  + +vsG+l +tv +W + tg+   ++  +gg+
   Q: 461  CPITSAYFFEKDnTLICSTYSIGILKGY-LEAQGPIKARKRTTHCSPLCAVLYSKIfKQVVSGCLRGTVSVWEVVTGRKTMEFavSGGQ 548
           3445555555332555555566666667.5555555557777777888888888888********************99999999999* PP
   S: 180  tdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdn 224
           +   + +++d++ ++l++g +dgt k+w++  g+c+ t+   ++ 
   Q: 549  HVEMTAMALDESERCLLTGLRDGTMKMWNYNIGKCLLTFPSPEQL 593
           ************************************999876655 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MSSEDLAEIP QLQKLSIPHG FQNKEAASPT PSITLSLVPD LQPGSQLFTE VHLAKIEKMF 60
EEDINSTGAL GMDAFIKAMK KVLSSVSDEM LKELFLKVDS DCEGFVTWQK YVDYMMREFQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCTTCTG AAGACTTAGC AGAGATCCCT CAACTCCAAA AGGTAAGAAA GACAATTATC 60
TGAACTAATA AAGGGTGGGG CATTCCAGAG TCACCCAAAA CCTCACTTAC CAGCATGGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011992--EF-hand-dom_pair
IPR002048--EF_hand_dom
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50222--EF_HAND_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005509--F:calcium ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cja-020006	Callithrix jacchus	88.05	0.00e+00	1385.00
IUUC-Cfa-020765	Canis familiaris	68.12	0.00e+00	1617.00
IUUC-Cin-025265	Ciona intestinalis	27.16	1.00e-71	265.00
IUUC-Dre-027573	Danio rerio	27.81	3.00e-60	226.00
IUUC-Dno-029238	Dasypus novemcinctus	62.20	0.00e+00	1553.00
IUUC-Dme-031984	Drosophila melanogaster	22.41	3.00e-50	194.00
IUUC-Hsa-046963	Homo sapiens	96.51	0.00e+00	2469.00
IUUC-Lch-050281	Latimeria chalumnae	39.74	7.00e-157	547.00
IUUC-Loc-052029	Lepisosteus oculatus	42.27	2.00e-157	549.00
IUUC-Laf-054508	Loxodonta africana	75.11	0.00e+00	701.00
IUUC-Mcc-054635	Macaca mulatta	91.69	0.00e+00	2367.00
IUUC-Mmr-061370	Microcebus murinus	67.85	0.00e+00	1620.00
IUUC-Mdo-061862	Monodelphis domestica	48.74	0.00e+00	1093.00
IUUC-Mmu-063271	Mus musculus	76.45	9.00e-167	579.00
IUUC-Mpu-066224	Mustela putorius furo	64.24	0.00e+00	1602.00
IUUC-Ocu-074664	Oryctolagus cuniculus	74.03	0.00e+00	1455.00
IUUC-Oar-089288	Ovis aries	66.92	0.00e+00	1634.00
IUUC-Psi-093985	Pelodiscus sinensis	43.81	4.00e-134	471.00
IUUC-Pfo-097353	Poecilia formosa	25.20	7.00e-54	205.00
IUUC-Smo-108683	Selaginella moellendorffii	24.03	9.00e-40	159.00
IUUC-Ssc-115233	Sus scrofa	78.30	6.00e-79	286.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence