iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-045288

UUCD1 version

UUC-GoG-00886

Ensembl Protein ID

ENSGGOP00000024541.1

UniProt Accession

G3S8X7; G3S8X7_GORGO

Protein Name

Uncharacterized protein

Gene Name

SOCS6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000023191.1	ENSGGOT00000029860.1	ENSGGOP00000024541.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	4.20e-17	62.2	488	535

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 2    sklwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedy 52
            ++ +++ ++rSLq+LCR++Ir++++++ +   +kLPLP+++kdYL++++y
   Q: 488  TNPVSRFMQVRSLQYLCRFVIRQYTRIDLI---QKLPLPNKMKDYLQEKHY 535
           5788999********************888...***************997 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MKKISLKTLR KSFNLNKSKE ETDFMVVQQP SLASDFGKDD SLFGSCYGKD MASCDINGED 60
EKSGKNRSKS ESLMGTLKRR LSAKQKSKGK AGTPSGSSAD EDTFSSSSAP IVFKDVRAQR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAAATGGCT CCAAAGGTTA AATGAAGCAG GAAAAATACA TAGATGCAGC CTTGCAGCCT 60
CTCCAGATGT TTGGGGATAA TATTCCAGAT AGAAATATTG ATCCCTTGGA TTAGGTAACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028421--SOCS6
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0001772--C:immunological synapse
GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0050868--P:negative regulation of T cell activation
GO:0010498--P:proteasomal protein catabolic process
GO:0016567--P:protein ubiquitination
GO:0040008--P:regulation of growth

KEGG

ggo:101150447

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001911	Ailuropoda melanoleuca	95.14	0.00e+00	955.00
IUUC-Atr-002940	Amborella trichopoda	26.36	1.20e-01	30.80
IUUC-Apl-004035	Anas platyrhynchos	90.09	0.00e+00	896.00
IUUC-Aca-004782	Anolis carolinensis	88.62	0.00e+00	868.00
IUUC-Ani-009490	Aspergillus nidulans	31.88	4.80e-02	32.00
IUUC-Ame-011790	Astyanax mexicanus	68.68	0.00e+00	643.00
IUUC-Bta-012579	Bos taurus	94.74	1.00e-108	386.00
IUUC-Bol-015843	Brassica oleracea	28.77	2.80e-02	33.10
IUUC-Cja-019528	Callithrix jacchus	97.57	0.00e+00	1026.00
IUUC-Cfa-020678	Canis familiaris	94.21	0.00e+00	967.00
IUUC-Cpo-021947	Cavia porcellus	94.95	0.00e+00	1002.00
IUUC-Csa-023935	Chlorocebus sabaeus	98.32	0.00e+00	1008.00
IUUC-Cho-024477	Choloepus hoffmanni	91.03	0.00e+00	958.00
IUUC-Cin-025413	Ciona intestinalis	68.24	3.00e-66	245.00
IUUC-Csv-026247	Ciona savignyi	67.47	4.00e-65	241.00
IUUC-Cne-026906	Cryptococcus neoformans	26.04	7.40e-02	32.30
IUUC-Dre-027636	Danio rerio	69.03	0.00e+00	639.00
IUUC-Dno-029048	Dasypus novemcinctus	93.64	0.00e+00	960.00
IUUC-Dor-030401	Dipodomys ordii	90.86	0.00e+00	920.00
IUUC-Ete-033116	Echinops telfairi	48.76	2.00e-58	219.00
IUUC-Eca-033825	Equus caballus	95.14	0.00e+00	932.00
IUUC-Fca-036253	Felis catus	92.90	0.00e+00	878.00
IUUC-Fal-037614	Ficedula albicollis	90.65	0.00e+00	900.00
IUUC-Fox-037898	Fusarium oxysporum	28.40	6.00e-03	34.30
IUUC-Gmo-038928	Gadus morhua	69.37	0.00e+00	678.00
IUUC-Gga-040177	Gallus gallus	89.91	0.00e+00	892.00
IUUC-Gac-042263	Gasterosteus aculeatus	70.72	0.00e+00	702.00
IUUC-Hsa-046409	Homo sapiens	99.25	0.00e+00	1018.00
IUUC-Itr-048996	Ictidomys tridecemlineatus	93.27	0.00e+00	933.00
IUUC-Lch-050354	Latimeria chalumnae	83.77	0.00e+00	874.00
IUUC-Loc-052319	Lepisosteus oculatus	81.16	0.00e+00	825.00
IUUC-Laf-054070	Loxodonta africana	92.15	0.00e+00	913.00
IUUC-Mcc-055045	Macaca mulatta	98.32	0.00e+00	1006.00
IUUC-Meu-055917	Macropus eugenii	90.47	0.00e+00	963.00
IUUC-Mga-059273	Meleagris gallopavo	90.28	0.00e+00	893.00
IUUC-Mmr-061597	Microcebus murinus	96.45	0.00e+00	989.00
IUUC-Mdo-062492	Monodelphis domestica	65.89	1.00e-113	402.00
IUUC-Mmu-063374	Mus musculus	84.01	0.00e+00	836.00
IUUC-Mpu-065967	Mustela putorius furo	89.35	0.00e+00	903.00
IUUC-Mlu-067532	Myotis lucifugus	92.71	0.00e+00	931.00
IUUC-Nle-069373	Nomascus leucogenys	98.88	0.00e+00	1013.00
IUUC-Opr-070873	Ochotona princeps	90.47	0.00e+00	962.00
IUUC-Ont-072498	Oreochromis niloticus	71.03	0.00e+00	732.00
IUUC-Oan-072943	Ornithorhynchus anatinus	71.22	1.00e-97	349.00
IUUC-Ocu-073870	Oryctolagus cuniculus	93.83	0.00e+00	962.00
IUUC-Ola-086866	Oryzias latipes	89.40	2.00e-105	374.00
IUUC-Oga-089057	Otolemur garnettii	92.71	0.00e+00	927.00
IUUC-Oar-089841	Ovis aries	61.57	9.00e-168	583.00
IUUC-Ptr-091054	Pan troglodytes	99.25	0.00e+00	1017.00
IUUC-Pma-094253	Petromyzon marinus	43.93	2.00e-101	362.00
IUUC-Pfo-097179	Poecilia formosa	64.88	1.00e-176	612.00
IUUC-Pab-097702	Pongo abelii	98.88	0.00e+00	1014.00
IUUC-Pca-100671	Procavia capensis	85.96	6.00e-129	454.00
IUUC-Rno-106044	Rattus norvegicus	81.34	0.00e+00	825.00
IUUC-Sha-107139	Sarcophilus harrisii	89.56	0.00e+00	880.00
IUUC-Smo-108823	Selaginella moellendorffii	33.96	3.60e-02	32.00
IUUC-Ssc-115343	Sus scrofa	91.96	0.00e+00	950.00
IUUC-Tgu-117061	Taeniopygia guttata	90.47	0.00e+00	900.00
IUUC-Tni-119829	Tetraodon nigroviridis	67.10	0.00e+00	645.00
IUUC-Tae-123723	Triticum aestivum	26.25	3.10e-02	33.90
IUUC-Ttr-129148	Tursiops truncatus	91.03	0.00e+00	897.00
IUUC-Vpa-130780	Vicugna pacos	89.16	0.00e+00	866.00
IUUC-Vvi-130966	Vitis vinifera	32.69	5.40e-02	31.20
IUUC-Xtr-132513	Xenopus tropicalis	82.43	0.00e+00	858.00
IUUC-Xma-133904	Xiphophorus maculatus	68.95	0.00e+00	671.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence