iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oga-088434

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03125175

Gene Name

UBA2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000008847.2	ENSOGAT00000008852.2	ENSOGAP00000007933.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	4.30e-138	461.0	10	421

Active Site

Position(s)	Description	Evidence
173	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR039133-1, ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 11   eaqeklksakvllvGagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesite 99
           e  e++   +vl+vGagg+GcEllKnLvl+G+++i ++D dt++vsnlnrqFLf++++vg+sKA+va+e++ ++ p+ n+ a+++s+++
   Q: 10   ELAEAVAGGRVLVVGAGGIGCELLKNLVLTGFSNIDLIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFYPKANIIAYHDSVMN 98
           56799999********************************************************************************* PP
   S: 100  leeeivFfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaehtie 188
           ++++++Ff++f +V++aldnr+ar++vnr+cl+a+vpliesgt G+lGqv++i kg+tecy+c+++p+q+t+P+ct+++tp+++ h+i+
   Q: 99   PDYNVEFFRQFILVMNALDNRAARNHVNRMCLAADVPLIESGTAGYLGQVTTIKKGVTECYECHPKPTQRTFPGCTIRNTPSEPIHCIV 187
           ***************************************************************************************** PP
   S: 189  wa.vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttins.ikqllksfecdivtkskspfwv. 274
           wa +lfn+l++ee++++ev++  d++++e++++++++e+++++++++ ++++i++k++ak+t ++ ik ++k f++di++  ++++++ 
   Q: 188  WAkYLFNQLFGEEDADQEVSP--DRADPEAAWEPTEAEARARASNEDGDIKRISTKEWAKSTGYDpIKLFTKLFKDDIRYLLTMDKLWr 274
           *********************..799*************************************************************** PP
   S: 275  .................sfcsnaealqvpekvekdeevvkasap.....lylllralerfekkkgrkpgelsfekdddsavdlvtaaan 341
                            +  + ++++++p+ ++kd++v++++++     +++++++++++ek +g    el ++kdd+sa+d+vt+aan
   Q: 275  krkppvpldwaevqsqgEETNASDQQNEPQLGLKDQQVLDVKSYaslfsKSIETLRVHLAEKGDGA---ELIWDKDDPSAMDFVTSAAN 360
           ****************999999********************************************...68****************** PP
   S: 342  lraeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKvvsgkfeplknfflfda 403
           lr++ +++++  ++++ik++agniipaiattnav++Gl+++E +K++sgk e+++++fl+++
   Q: 361  LRMHIFSMNM-KSRFDIKSMAGNIIPAIATTNAVIAGLIVLEGLKILSGKIEQCRTIFLNKQ 421
           **********.***********************************************9965 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MALSRGLPRE LAEAVAGGRV LVVGAGGIGC ELLKNLVLTG FSNIDLIDLD TIDVSNLNRQ 60
FLFQKKHVGR SKAQVAKESV LQFYPKANII AYHDSVMNPD YNVEFFRQFI LVMNALDNRA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCGGGGCTT ACTTCTCCCG CCTCCGCCGC GCTCGTGGTC GTCCCGCCAT GGCGCTGTCG 60
CGGGGGCTTC CCCGGGAGCT GGCTGAGGCA GTGGCCGGAG GCCGGGTGTT GGTGGTGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016040--NAD(P)-bd_dom
IPR030661--SAE2/Uba2
IPR000594--ThiF_NAD_FAD-bd
IPR028077--UAE_UbL_dom
IPR032426--UBA2_C
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF00899--ThiF
PF14732--UAE_UbL
PF16195--UBA2_C

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0031510--C:SUMO activating enzyme complex
GO:0019948--F:SUMO activating enzyme activity
GO:0016925--P:protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000112	Aegilops tauschii	40.44	2.00e-108	386.00
IUUC-Aml-001662	Ailuropoda melanoleuca	97.04	0.00e+00	1241.00
IUUC-Atr-002636	Amborella trichopoda	40.32	2.00e-114	406.00
IUUC-Apl-003369	Anas platyrhynchos	88.72	0.00e+00	1026.00
IUUC-Aca-004490	Anolis carolinensis	82.58	0.00e+00	918.00
IUUC-Aly-006359	Arabidopsis lyrata	42.20	5.00e-105	375.00
IUUC-Ath-007667	Arabidopsis thaliana	42.75	2.00e-108	386.00
IUUC-Ago-007844	Ashbya gossypii	36.74	7.00e-85	308.00
IUUC-Acl-008270	Aspergillus clavatus	42.68	4.00e-105	375.00
IUUC-Afl-008674	Aspergillus flavus	43.46	1.00e-112	400.00
IUUC-Afu-008883	Aspergillus fumigatus	41.50	1.00e-106	380.00
IUUC-Ani-009500	Aspergillus nidulans	44.68	1.00e-115	410.00
IUUC-Ang-009535	Aspergillus niger	43.08	6.00e-110	391.00
IUUC-Aor-010223	Aspergillus oryzae	43.57	2.00e-114	405.00
IUUC-Ate-010282	Aspergillus terreus	43.69	5.00e-90	325.00
IUUC-Ame-011736	Astyanax mexicanus	77.44	0.00e+00	990.00
IUUC-Bgr-012166	Blumeria graminis	42.26	1.00e-98	353.00
IUUC-Bta-012589	Bos taurus	96.88	0.00e+00	1246.00
IUUC-Bci-013802	Botrytis cinerea	43.02	7.00e-101	361.00
IUUC-Bdi-014697	Brachypodium distachyon	41.76	5.00e-112	398.00
IUUC-Bol-016315	Brassica oleracea	39.97	2.00e-111	396.00
IUUC-Bra-017009	Brassica rapa	39.79	4.00e-112	398.00
IUUC-Cel-018708	Caenorhabditis elegans	46.48	3.00e-133	468.00
IUUC-Cja-019120	Callithrix jacchus	97.81	0.00e+00	1210.00
IUUC-Cfa-021061	Canis familiaris	97.34	0.00e+00	1250.00
IUUC-Cpo-021842	Cavia porcellus	96.41	0.00e+00	1200.00
IUUC-Csa-024104	Chlorocebus sabaeus	97.82	0.00e+00	1176.00
IUUC-Cho-024332	Choloepus hoffmanni	86.52	0.00e+00	874.00
IUUC-Cin-025363	Ciona intestinalis	56.38	0.00e+00	681.00
IUUC-Cgl-026419	Colletotrichum gloeosporioides	42.14	6.00e-98	351.00
IUUC-Cne-026888	Cryptococcus neoformans	39.89	1.00e-73	271.00
IUUC-Cme-027315	Cyanidioschyzon merolae	33.99	2.00e-59	224.00
IUUC-Dre-028420	Danio rerio	76.42	0.00e+00	920.00
IUUC-Dno-030041	Dasypus novemcinctus	97.04	0.00e+00	1208.00
IUUC-Dor-031039	Dipodomys ordii	81.80	0.00e+00	649.00
IUUC-Dse-031504	Dothistroma septosporum	42.99	5.00e-94	338.00
IUUC-Dme-031771	Drosophila melanogaster	50.41	2.00e-148	519.00
IUUC-Ete-033037	Echinops telfairi	90.78	0.00e+00	1078.00
IUUC-Eca-033774	Equus caballus	97.64	0.00e+00	1204.00
IUUC-Eeu-035074	Erinaceus europaeus	96.30	0.00e+00	966.00
IUUC-Fca-036508	Felis catus	97.64	0.00e+00	1206.00
IUUC-Fal-036813	Ficedula albicollis	86.66	0.00e+00	1021.00
IUUC-Fox-038056	Fusarium oxysporum	43.58	5.00e-106	378.00
IUUC-Fso-038223	Fusarium solani	42.33	4.00e-104	372.00
IUUC-Gmo-038526	Gadus morhua	75.04	0.00e+00	902.00
IUUC-Ggr-039767	Gaeumannomyces graminis	43.74	2.00e-100	360.00
IUUC-Gga-040981	Gallus gallus	88.12	0.00e+00	1056.00
IUUC-Gac-041437	Gasterosteus aculeatus	76.18	0.00e+00	927.00
IUUC-Gma-044072	Glycine max	37.78	5.00e-114	405.00
IUUC-Ggo-045358	Gorilla gorilla	94.43	0.00e+00	1120.00
IUUC-Hsa-046068	Homo sapiens	97.97	0.00e+00	1181.00
IUUC-Hvu-047646	Hordeum vulgare	38.57	1.00e-107	383.00
IUUC-Itr-047887	Ictidomys tridecemlineatus	96.88	0.00e+00	1198.00
IUUC-Lch-049565	Latimeria chalumnae	81.34	0.00e+00	1040.00
IUUC-Lpe-050884	Leersia perrieri	40.82	9.00e-109	387.00
IUUC-Loc-052493	Lepisosteus oculatus	81.43	0.00e+00	1025.00
IUUC-Lma-053117	Leptosphaeria maculans	43.98	1.00e-101	363.00
IUUC-Laf-054518	Loxodonta africana	93.76	0.00e+00	1177.00
IUUC-Mcc-055334	Macaca mulatta	97.66	0.00e+00	1179.00
IUUC-Mor-057137	Magnaporthe oryzae	42.88	1.00e-94	340.00
IUUC-Mpo-057449	Magnaporthe poae	41.01	2.00e-102	366.00
IUUC-Mtr-058045	Medicago truncatula	39.43	3.00e-117	415.00
IUUC-Mla-058864	Melampsora laricipopulina	45.51	5.00e-96	344.00
IUUC-Mga-059422	Meleagris gallopavo	83.03	0.00e+00	935.00
IUUC-Mvi-060536	Microbotryum violaceum	41.68	6.00e-87	315.00
IUUC-Mmr-061161	Microcebus murinus	96.78	0.00e+00	1211.00
IUUC-Mdo-061802	Monodelphis domestica	92.36	0.00e+00	1138.00
IUUC-Mmu-064357	Mus musculus	93.28	0.00e+00	1191.00
IUUC-Mac-065475	Musa acuminata	39.23	4.00e-111	395.00
IUUC-Mpu-066895	Mustela putorius furo	97.50	0.00e+00	1249.00
IUUC-Mlu-067862	Myotis lucifugus	96.26	0.00e+00	1237.00
IUUC-Nfi-068385	Neosartorya fischeri	43.27	7.00e-110	391.00
IUUC-Ncr-068885	Neurospora crassa	41.50	1.00e-107	384.00
IUUC-Nle-069524	Nomascus leucogenys	97.19	0.00e+00	1163.00
IUUC-Opr-071038	Ochotona princeps	96.88	0.00e+00	1242.00
IUUC-Ont-071719	Oreochromis niloticus	75.83	0.00e+00	984.00
IUUC-Oan-072877	Ornithorhynchus anatinus	90.07	0.00e+00	995.00
IUUC-Ocu-074080	Oryctolagus cuniculus	96.88	0.00e+00	1194.00
IUUC-Oba-075936	Oryza barthii	37.66	2.00e-109	389.00
IUUC-Obr-076841	Oryza brachyantha	38.13	5.00e-111	395.00
IUUC-Ogl-077686	Oryza glaberrima	37.72	7.00e-111	394.00
IUUC-Ogu-078597	Oryza glumaepatula	36.79	3.00e-106	379.00
IUUC-Oin-079791	Oryza indica	37.66	2.00e-109	389.00
IUUC-Olo-081009	Oryza longistaminata	37.82	8.00e-110	390.00
IUUC-Ome-081327	Oryza meridionalis	35.50	3.00e-104	372.00
IUUC-Oni-082334	Oryza nivara	36.96	1.00e-106	380.00
IUUC-Opu-083447	Oryza punctata	37.97	5.00e-111	394.00
IUUC-Oru-084977	Oryza rufipogon	37.64	9.00e-109	387.00
IUUC-Osa-086160	Oryza sativa	43.98	4.00e-96	344.00
IUUC-Ola-087415	Oryzias latipes	75.59	0.00e+00	936.00
IUUC-Olu-087850	Ostreococcus lucimarinus	39.81	1.00e-101	363.00
IUUC-Oar-089872	Ovis aries	96.81	0.00e+00	1196.00
IUUC-Ptr-091212	Pan troglodytes	97.97	0.00e+00	1181.00
IUUC-Pan-092708	Papio anubis	98.07	1.00e-131	463.00
IUUC-Psi-093703	Pelodiscus sinensis	90.40	0.00e+00	1050.00
IUUC-Pno-094953	Phaeosphaeria nodorum	45.83	1.00e-105	377.00
IUUC-Ppa-095963	Physcomitrella patens	44.16	6.00e-108	384.00
IUUC-Pfo-097515	Poecilia formosa	74.76	0.00e+00	936.00
IUUC-Pab-097951	Pongo abelii	97.98	0.00e+00	1027.00
IUUC-Pop-099703	Populus trichocarpa	36.63	4.00e-96	345.00
IUUC-Pca-100426	Procavia capensis	94.22	0.00e+00	1206.00
IUUC-Ppe-101152	Prunus persica	38.93	5.00e-112	398.00
IUUC-Pva-102792	Pteropus vampyrus	92.43	0.00e+00	1150.00
IUUC-Pgr-103592	Puccinia graminis	43.12	5.00e-100	358.00
IUUC-Ptt-103805	Puccinia triticina	41.70	2.00e-86	313.00
IUUC-Pte-104215	Pyrenophora teres	39.09	6.00e-113	401.00
IUUC-Pyt-104634	Pyrenophora triticirepentis	42.23	3.00e-111	395.00
IUUC-Rno-106117	Rattus norvegicus	93.75	0.00e+00	1197.00
IUUC-Sce-106177	Saccharomyces cerevisiae	34.52	4.00e-76	278.00
IUUC-Sha-107006	Sarcophilus harrisii	92.37	0.00e+00	1140.00
IUUC-Sja-107967	Schizosaccharomyces japonicus	43.74	7.00e-95	341.00
IUUC-Spo-108020	Schizosaccharomyces pombe	44.17	1.00e-95	343.00
IUUC-Ssl-108509	Sclerotinia sclerotiorum	43.26	2.00e-103	370.00
IUUC-Smo-109264	Selaginella moellendorffii	43.67	5.00e-107	381.00
IUUC-Sit-110581	Setaria italica	40.84	2.00e-109	389.00
IUUC-Sly-111870	Solanum lycopersicum	39.51	3.00e-112	399.00
IUUC-Stu-112283	Solanum tuberosum	39.64	9.00e-110	390.00
IUUC-Sar-113432	Sorex araneus	71.61	0.00e+00	791.00
IUUC-Sbi-114075	Sorghum bicolor	37.80	2.00e-109	390.00
IUUC-Sre-114926	Sporisorium reilianum	43.22	3.00e-105	375.00
IUUC-Ssc-116281	Sus scrofa	98.17	2.00e-117	414.00
IUUC-Tgu-117247	Taeniopygia guttata	85.21	0.00e+00	1017.00
IUUC-Tru-118075	Takifugu rubripes	71.36	0.00e+00	896.00
IUUC-Tsy-119398	Tarsius syrichta	81.41	0.00e+00	932.00
IUUC-Tni-120771	Tetraodon nigroviridis	66.26	0.00e+00	811.00
IUUC-Tca-121651	Theobroma cacao	39.75	2.00e-110	393.00
IUUC-Tre-122224	Trichoderma reesei	43.44	3.00e-95	342.00
IUUC-Tvi-122634	Trichoderma virens	43.26	2.00e-95	343.00
IUUC-Tae-125665	Triticum aestivum	40.56	4.00e-106	378.00
IUUC-Tur-126417	Triticum urartu	39.60	8.00e-107	381.00
IUUC-Tme-127016	Tuber melanosporum	44.66	2.00e-96	346.00
IUUC-Tbe-127678	Tupaia belangeri	81.72	8.00e-178	617.00
IUUC-Ttr-128598	Tursiops truncatus	93.44	0.00e+00	1184.00
IUUC-Uma-129612	Ustilago maydis	41.42	3.00e-97	349.00
IUUC-Vda-129811	Verticillium dahliae	40.59	5.00e-102	365.00
IUUC-Vpa-130732	Vicugna pacos	83.44	0.00e+00	1027.00
IUUC-Vvi-130832	Vitis vinifera	41.91	5.00e-107	381.00
IUUC-Xtr-132823	Xenopus tropicalis	76.63	0.00e+00	926.00
IUUC-Xma-133552	Xiphophorus maculatus	74.61	0.00e+00	935.00
IUUC-Yli-134666	Yarrowia lipolytica	37.87	1.00e-76	280.00
IUUC-Zma-135547	Zea mays	38.14	1.00e-108	386.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence