iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000077948.4	ENSDART00000173379.1	ENSDARP00000142525.1
ENSDARG00000077948.4	ENSDART00000173258.1	ENSDARP00000142440.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.80e-26	92.0	32	349

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNl..gNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavspre.....llkalkkeaee 83
           Gl N   +N+C++NS+LQ+L+++  +r+ + + +++k+ e+       ++ ++l+++f+++ + ++++v p++     l k++++e+ +
   Q: 32   GLINEpgQNSCFLNSALQVLWHLDIFRRSFRQLTTHKCMED------SCIFCALKSIFAQF-QFSSEKVLPSDalrcaLAKTFQDEQ-R 112
           77786668************************999999875......69************.6666666666655555666666554.5 PP
   S: 84   fsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
           f+     Da E+++ +l +++ ++                   sde +e+  + ++++ ++ F ++l +q++c +c+ +s    pf+++
   Q: 113  FQLGIMDDAAECFENILMRIHFHI-------------------SDETKEDICTAKHCIPHQKFAMTLFEQCVCSNCGASSDPL-PFIQM 181
           99**********************...................455677899*************************999665.9**** PP
   S: 173  slpvpgkeetkke.........slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkk 252
              ++  + +++             d++ +  ++ +  g+ +    +c +k +  +++ +++ Pe++++ L +   s + +  e +  +
   Q: 182  VHYISTTSLCNQAvrmlecrekPTPDMFGELLRNASTVGDLRNCPGNCGEKLR-IRRVLMNS-PEIITIGLVWD--SDHSDLAEDVIHS 266
           *****999998889999999998899999999999999999888899999885.66666665.**********9..4444555555555 PP
   S: 253  vefpleLdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtev..keeevleetg...staYvlfY 335
           + +   L l     + +e+++++ +  L++vv+++G     HY ++  ++k + W++fdD +V+e+  k+++v++ +     ++ +l+Y
   Q: 267  LGTV--LRLGDLFYRVTEDKAKQAELYLVGVVCYYG----KHYSTFFFQTKIRkWIYFDDAHVKEIgpKWKDVVSRCIkghYQPLLLLY 349
           5555..555552222223333355555*********....9*****99987767************76689998855455555556666 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MSWKRNYFAS GSSGLQGIFT PRTMTSIAPS KGLINEPGQN SCFLNSALQV LWHLDIFRRS 60
FRQLTTHKCM EDSCIFCALK SIFAQFQFSS EKVLPSDALR CALAKTFQDE QRFQLGIMDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACCAAATCCA AATCGCACTT CGTTGACACC TGAGACGCCA AGCATCGCGA GAGTTGGTTG 60
CCTTGGCTGC AGCACACAGT GACGCTGAGG GATGTTTAAG GTTTAGCTTC AGAAAATAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR028889--USP_dom

PROSITE

PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000820	Aegilops tauschii	29.50	2.00e-19	90.10
IUUC-Aml-001414	Ailuropoda melanoleuca	62.59	0.00e+00	945.00
IUUC-Apl-004044	Anas platyrhynchos	62.29	0.00e+00	938.00
IUUC-Aca-004351	Anolis carolinensis	64.76	0.00e+00	985.00
IUUC-Aly-005468	Arabidopsis lyrata	33.05	7.00e-43	170.00
IUUC-Ame-011525	Astyanax mexicanus	81.36	0.00e+00	1353.00
IUUC-Bta-013344	Bos taurus	63.41	0.00e+00	957.00
IUUC-Bdi-015058	Brachypodium distachyon	34.71	1.00e-45	179.00
IUUC-Bol-015670	Brassica oleracea	33.82	9.00e-41	162.00
IUUC-Bra-016731	Brassica rapa	33.72	1.00e-41	166.00
IUUC-Cja-018724	Callithrix jacchus	63.67	0.00e+00	969.00
IUUC-Cfa-021222	Canis familiaris	63.24	0.00e+00	996.00
IUUC-Cpo-021795	Cavia porcellus	61.46	0.00e+00	987.00
IUUC-Csa-023262	Chlorocebus sabaeus	63.77	0.00e+00	969.00
IUUC-Cho-024422	Choloepus hoffmanni	58.12	0.00e+00	914.00
IUUC-Dno-029417	Dasypus novemcinctus	63.30	0.00e+00	865.00
IUUC-Dme-032071	Drosophila melanogaster	52.46	6.00e-105	376.00
IUUC-Eca-033235	Equus caballus	63.93	0.00e+00	942.00
IUUC-Fca-036070	Felis catus	63.49	0.00e+00	963.00
IUUC-Fal-037089	Ficedula albicollis	63.18	0.00e+00	1085.00
IUUC-Gga-041241	Gallus gallus	65.33	0.00e+00	1084.00
IUUC-Ggo-045626	Gorilla gorilla	63.56	0.00e+00	963.00
IUUC-Hsa-045767	Homo sapiens	63.67	0.00e+00	966.00
IUUC-Hvu-047657	Hordeum vulgare	33.83	7.00e-46	180.00
IUUC-Lch-049712	Latimeria chalumnae	89.09	0.00e+00	728.00
IUUC-Lpe-051572	Leersia perrieri	33.23	9.00e-42	166.00
IUUC-Loc-052615	Lepisosteus oculatus	75.58	0.00e+00	1189.00
IUUC-Mcc-054696	Macaca mulatta	63.77	0.00e+00	968.00
IUUC-Mmr-060701	Microcebus murinus	62.43	0.00e+00	939.00
IUUC-Mdo-062433	Monodelphis domestica	64.18	0.00e+00	992.00
IUUC-Mpu-066404	Mustela putorius furo	63.24	0.00e+00	988.00
IUUC-Nle-070110	Nomascus leucogenys	63.67	0.00e+00	966.00
IUUC-Opr-070676	Ochotona princeps	58.93	0.00e+00	735.00
IUUC-Ont-072289	Oreochromis niloticus	66.57	0.00e+00	779.00
IUUC-Oan-073551	Ornithorhynchus anatinus	62.75	0.00e+00	972.00
IUUC-Ocu-074729	Oryctolagus cuniculus	65.13	0.00e+00	999.00
IUUC-Obr-076268	Oryza brachyantha	33.43	2.00e-43	172.00
IUUC-Ogl-077138	Oryza glaberrima	32.84	6.00e-42	167.00
IUUC-Oin-079125	Oryza indica	32.84	8.00e-42	166.00
IUUC-Opu-083823	Oryza punctata	32.84	4.00e-42	167.00
IUUC-Osa-085583	Oryza sativa	32.84	5.00e-41	162.00
IUUC-Ola-086742	Oryzias latipes	83.38	0.00e+00	662.00
IUUC-Oga-088920	Otolemur garnettii	63.24	0.00e+00	976.00
IUUC-Oar-089644	Ovis aries	63.13	0.00e+00	952.00
IUUC-Ptr-091530	Pan troglodytes	63.67	0.00e+00	966.00
IUUC-Pan-092190	Papio anubis	63.77	0.00e+00	967.00
IUUC-Psi-094022	Pelodiscus sinensis	64.83	0.00e+00	1001.00
IUUC-Pab-097979	Pongo abelii	63.07	0.00e+00	962.00
IUUC-Pca-101005	Procavia capensis	72.97	8.00e-170	592.00
IUUC-Pva-103125	Pteropus vampyrus	62.92	0.00e+00	979.00
IUUC-Rno-105463	Rattus norvegicus	63.67	0.00e+00	944.00
IUUC-Sha-107164	Sarcophilus harrisii	67.49	0.00e+00	851.00
IUUC-Sit-110021	Setaria italica	33.14	3.00e-40	161.00
IUUC-Sly-111258	Solanum lycopersicum	33.24	3.00e-39	158.00
IUUC-Sbi-114345	Sorghum bicolor	34.02	5.00e-44	174.00
IUUC-Ssc-116206	Sus scrofa	62.67	0.00e+00	900.00
IUUC-Tru-118155	Takifugu rubripes	75.00	0.00e+00	635.00
IUUC-Tsy-118998	Tarsius syrichta	58.43	0.00e+00	855.00
IUUC-Tca-121692	Theobroma cacao	32.65	2.00e-40	162.00
IUUC-Tae-125619	Triticum aestivum	34.41	1.00e-46	182.00
IUUC-Tur-126027	Triticum urartu	34.51	2.00e-46	182.00
IUUC-Ttr-128290	Tursiops truncatus	60.99	0.00e+00	895.00
IUUC-Vpa-130213	Vicugna pacos	59.57	0.00e+00	904.00
IUUC-Xtr-131831	Xenopus tropicalis	64.28	0.00e+00	1033.00
IUUC-Xma-133409	Xiphophorus maculatus	67.38	0.00e+00	965.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence