iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004572

UUCD1 version

UUC-AnC-00720

Ensembl Protein ID

ENSACAP00000011702.2

UniProt Accession

G1KLP3; G1KLP3_ANOCA

Protein Name

Uncharacterized protein

Gene Name

EML6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000011806.3	ENSACAT00000011943.3	ENSACAP00000011702.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.30e-61	199.1	105	144
UBD/Beta-Prp	3.10e-130	433.7	57	264

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdD..gtikvWDlrtgvllk 37
           Ht +v claf sd  +l+s + D  +t+ +WD+++g+ll 
   Q: 105  HTHGVACLAFdSDgQRLASVGLDakNTVCIWDWKKGKLLA 144
           9**********999*******9999**********99875 PP

UBD/Beta-Prp

   S: 5    lkghhksvitcvkfspdksllatg..srdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvh 88
           + gh+++ i+ ++ +pdk+l+atg  ++d  i +wd  + ++++ l   h+ +v+++ f++dg+ l++++ D  +t+++wd ++gk + 
   Q: 57   FLGHNDDIIS-LALHPDKTLVATGqvGKDPYICIWDSYNVQTVSILkDAHTHGVACLAFDSDGQRLASVGLDakNTVCIWDWKKGKLLA 144
           5578888888.9999********95558999***************888**************************************** PP
   S: 89   tlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee..tlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrt 174
           + +gh+d++ ++s++p++   v+   ++ i+ w l  +    +  ++ ++ ++ +++++++ + ++  sG+l++ + +W+    +l+rt
   Q: 145  SATGHSDRIFDISWDPYQPNRVASCGVKHIKFWTLCGNALTAKrgIFGKTGDLQTILCLSCAKdDVTYSGALNGDIYVWKG--LTLVRT 231
           ****************9977777778*******9999999988996666666666666666666999************66..99**** PP
   S: 175  ltgghtdsvyslsfdsngkelvsgsldgtvklwdl 209
            +g+h   + s+   ++g  +++g++dg ++lwd+
   Q: 232  IQGAHGAGIFSMYACEEG--FATGGRDGCIRLWDV 264
           ************999965..**************6 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MADRTAPRCQ LRLEWVYGYR GHQCRNNLYY TAGKEVVYFV AGVGVVYNTR EHSQKFFLGH 60
NDDIISLALH PDKTLVATGQ VGKDPYICIW DSYNVQTVSI LKDAHTHGVA CLAFDSDGQR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTTTTCCTG TCTCTGCACT GAGAGGCAAA TTATGATGAG GAAAACCGAC AGAAGGTTGC 60
ATCTTTGCTC AGCCACAGAA TGAACTGGAA TTTGCACTCG GCAATTCAAA AGGAAAAGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR005108--HELP
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0015630--C:microtubule cytoskeleton
GO:0008017--F:microtubule binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001387	Ailuropoda melanoleuca	89.81	0.00e+00	3584.00
IUUC-Apl-003604	Anas platyrhynchos	91.84	0.00e+00	3631.00
IUUC-Ame-010713	Astyanax mexicanus	77.73	0.00e+00	3139.00
IUUC-Bta-012812	Bos taurus	89.71	0.00e+00	3583.00
IUUC-Cja-019191	Callithrix jacchus	89.28	0.00e+00	3544.00
IUUC-Cfa-020041	Canis familiaris	89.96	0.00e+00	3346.00
IUUC-Cpo-022304	Cavia porcellus	70.58	0.00e+00	2806.00
IUUC-Cre-022931	Chlamydomonas reinhardtii	34.72	7.00e-102	367.00
IUUC-Csa-023689	Chlorocebus sabaeus	89.64	0.00e+00	3488.00
IUUC-Cho-025038	Choloepus hoffmanni	89.19	0.00e+00	1387.00
IUUC-Cin-025205	Ciona intestinalis	60.35	0.00e+00	2479.00
IUUC-Csv-026014	Ciona savignyi	61.45	0.00e+00	2488.00
IUUC-Dre-028772	Danio rerio	72.05	0.00e+00	3014.00
IUUC-Dno-029982	Dasypus novemcinctus	87.89	0.00e+00	3415.00
IUUC-Dor-030980	Dipodomys ordii	70.25	0.00e+00	1299.00
IUUC-Eca-034161	Equus caballus	88.73	0.00e+00	3439.00
IUUC-Eeu-035180	Erinaceus europaeus	60.35	0.00e+00	1076.00
IUUC-Fca-036307	Felis catus	90.26	0.00e+00	3591.00
IUUC-Fal-037332	Ficedula albicollis	89.78	0.00e+00	3536.00
IUUC-Gmo-039146	Gadus morhua	69.98	0.00e+00	2889.00
IUUC-Gga-041095	Gallus gallus	74.41	0.00e+00	2200.00
IUUC-Gac-042555	Gasterosteus aculeatus	76.94	0.00e+00	3129.00
IUUC-Ggo-045107	Gorilla gorilla	89.96	0.00e+00	3585.00
IUUC-Hsa-046482	Homo sapiens	90.11	0.00e+00	3586.00
IUUC-Itr-049023	Ictidomys tridecemlineatus	88.64	0.00e+00	3481.00
IUUC-Lch-050306	Latimeria chalumnae	71.55	0.00e+00	2682.00
IUUC-Loc-052642	Lepisosteus oculatus	84.89	0.00e+00	3375.00
IUUC-Laf-053649	Loxodonta africana	87.89	0.00e+00	3476.00
IUUC-Mcc-055361	Macaca mulatta	89.19	0.00e+00	3123.00
IUUC-Meu-056618	Macropus eugenii	79.39	0.00e+00	1675.00
IUUC-Mga-059202	Meleagris gallopavo	90.89	0.00e+00	3506.00
IUUC-Mmr-060729	Microcebus murinus	88.41	0.00e+00	3583.00
IUUC-Mdo-062462	Monodelphis domestica	90.05	0.00e+00	3486.00
IUUC-Mmu-063865	Mus musculus	89.30	0.00e+00	3586.00
IUUC-Mpu-066724	Mustela putorius furo	90.31	0.00e+00	3595.00
IUUC-Mlu-067816	Myotis lucifugus	90.01	0.00e+00	3601.00
IUUC-Nle-069911	Nomascus leucogenys	73.51	0.00e+00	3017.00
IUUC-Opr-070213	Ochotona princeps	87.82	0.00e+00	1890.00
IUUC-Ont-071928	Oreochromis niloticus	77.69	0.00e+00	3149.00
IUUC-Oan-073563	Ornithorhynchus anatinus	89.79	0.00e+00	3569.00
IUUC-Ocu-074531	Oryctolagus cuniculus	89.86	0.00e+00	3583.00
IUUC-Ola-086943	Oryzias latipes	75.71	0.00e+00	3006.00
IUUC-Olu-087860	Ostreococcus lucimarinus	38.73	3.00e-117	415.00
IUUC-Oga-088665	Otolemur garnettii	89.01	0.00e+00	3449.00
IUUC-Oar-090429	Ovis aries	89.91	0.00e+00	3591.00
IUUC-Ptr-091168	Pan troglodytes	83.04	0.00e+00	3237.00
IUUC-Pan-092404	Papio anubis	73.36	0.00e+00	3008.00
IUUC-Psi-093281	Pelodiscus sinensis	90.87	0.00e+00	3633.00
IUUC-Pma-094424	Petromyzon marinus	70.86	1.00e-121	428.00
IUUC-Pfo-096073	Poecilia formosa	72.91	0.00e+00	3047.00
IUUC-Pab-098561	Pongo abelii	88.65	0.00e+00	3106.00
IUUC-Pca-100107	Procavia capensis	61.34	0.00e+00	1924.00
IUUC-Pva-102880	Pteropus vampyrus	70.21	0.00e+00	2735.00
IUUC-Rno-105002	Rattus norvegicus	89.10	0.00e+00	3567.00
IUUC-Sha-107105	Sarcophilus harrisii	87.25	0.00e+00	3357.00
IUUC-Sar-113401	Sorex araneus	63.15	0.00e+00	1375.00
IUUC-Ssc-116282	Sus scrofa	89.73	0.00e+00	3486.00
IUUC-Tgu-116807	Taeniopygia guttata	90.31	0.00e+00	3577.00
IUUC-Tru-118040	Takifugu rubripes	76.25	0.00e+00	3083.00
IUUC-Tsy-118941	Tarsius syrichta	63.99	0.00e+00	2202.00
IUUC-Tni-120118	Tetraodon nigroviridis	73.89	0.00e+00	3043.00
IUUC-Tbe-127467	Tupaia belangeri	66.98	0.00e+00	1397.00
IUUC-Ttr-129138	Tursiops truncatus	70.56	0.00e+00	2765.00
IUUC-Vpa-130083	Vicugna pacos	69.59	0.00e+00	2652.00
IUUC-Xtr-131835	Xenopus tropicalis	72.86	0.00e+00	3045.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence