iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pab-098542

Ensembl Protein ID

ENSPPYP00000017832.2

UniProt Accession

H2PH18; H2PH18_PONAB

Genbank Protein ID

ENSPPYP00000017832

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01119610

Gene Name

ARHGEF37

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000015937.2	ENSPPYT00000018547.2	ENSPPYP00000017832.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.10e-10	41.3	615	674

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlvi..ekeeqdegWlkgvkelegkrGlfPenFvekle 63
           ++v++ y++ a ++ e +l++G  v+++  ++++ + +W     e +g+rG +P+ F ++++
   Q: 615  NQVIAAYPFVARSSHEVSLQAGQPVTILeaQDKKGNPEWSLV--EVNGQRGYVPSGFLVRAR 674
           7899************************9889999****977..9************99875 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MLLLFPETAD MAKHGADEPS SRSGSPDGEG RASEDRSLLH QRLAVRELID TEVSYLHMLQ 60
LCASDIRSRL QQLPQGDLDV LFSNIDDIIK VNSRFLHDLQ ETASKKEEQV QLVGNIFLEF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TAGAGACAGC ATGTCCCAAT AGTTCTTCCT GGAAGTGAGT GGGGATGCTT TTGCTTTTCC 60
CAGAAACTGC TGACATGGCC AAGCATGGAG CCGACGAGCC GTCCTCCAGG TCAGGAAGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR027267--AH/BAR-dom
IPR004148--BAR_dom
IPR000219--DH-domain
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS51021--BAR
PS50010--DH_2
PS50002--SH3

Pfam

PF00621--RhoGEF
PF00018--SH3_1
PF07653--SH3_2

SMART

SM00721--BAR
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-011907	Astyanax mexicanus	39.50	2.00e-127	449.00
IUUC-Bta-012848	Bos taurus	85.63	0.00e+00	1109.00
IUUC-Cfa-021281	Canis familiaris	84.59	0.00e+00	1092.00
IUUC-Csa-023043	Chlorocebus sabaeus	96.44	0.00e+00	1277.00
IUUC-Dre-028496	Danio rerio	39.45	1.00e-125	444.00
IUUC-Ete-032921	Echinops telfairi	62.50	3.00e-71	261.00
IUUC-Ggo-044900	Gorilla gorilla	98.37	0.00e+00	1293.00
IUUC-Hsa-045684	Homo sapiens	98.22	0.00e+00	1328.00
IUUC-Lch-050096	Latimeria chalumnae	46.39	7.00e-168	583.00
IUUC-Loc-051937	Lepisosteus oculatus	41.44	3.00e-131	462.00
IUUC-Mcc-054950	Macaca mulatta	95.70	0.00e+00	1267.00
IUUC-Meu-056383	Macropus eugenii	69.67	7.00e-173	600.00
IUUC-Mdo-062021	Monodelphis domestica	68.36	0.00e+00	882.00
IUUC-Mmu-064186	Mus musculus	79.29	0.00e+00	1025.00
IUUC-Ptr-090508	Pan troglodytes	98.67	0.00e+00	1297.00
IUUC-Pan-092517	Papio anubis	95.91	0.00e+00	1262.00
IUUC-Pfo-096703	Poecilia formosa	39.44	3.00e-122	432.00
IUUC-Rno-105455	Rattus norvegicus	80.47	0.00e+00	1046.00
IUUC-Sha-106562	Sarcophilus harrisii	69.66	0.00e+00	870.00
IUUC-Ttr-128242	Tursiops truncatus	81.63	0.00e+00	1065.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence