iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-045175

UUCD1 version

UUC-GoG-00727

Ensembl Protein ID

ENSGGOP00000018636.1

UniProt Accession

G3RS61; G3RS61_GORGO

Protein Name

Uncharacterized protein

Gene Name

CBLB

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000022475.1	ENSGGOT00000028659.1	ENSGGOP00000018636.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.10e-07	32.7	373	412

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC e  kd +++ pCgH+++++Cl +w    ++s ++  CP Cr
   Q: 373  CKICAENDKD-VKIEPCGHLMCTSCLTAW----QESDGQ-GCPFCR 412
           99********.******************....555555.5****8 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MANSMNGRNP GGRGGNPRKG RILGIIDAIQ DAVGPPKQAA ADRRTVEKTW KLMDKVVRLC 60
QNPKLQLKNS PPYILDILPD TYQHLRLILS KYDDNQKLAQ LSENEYFKIY IDSLMKKSKR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCAGCCCCA GATGGCTTTG GCTCCCGGTC CCGACGCTCA CGCCCACCTG CCACCCCTTA 60
TTGGTTAGCT CCTTCGTGCC TTGCATCCCT TCGTCCATTT CCTTTCCCGT TTCCACTTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR024162--Adaptor_Cbl
IPR014741--Adaptor_Cbl_EF_hand-like
IPR003153--Adaptor_Cbl_N_hlx
IPR014742--Adaptor_Cbl_SH2-like
IPR024159--Cbl_PTB
IPR011992--EF-hand-dom_pair
IPR000980--SH2
IPR015940--UBA
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51506--CBL_PTB
PS50030--UBA
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02262--Cbl_N
PF02761--Cbl_N2
PF02762--Cbl_N3

SMART

SM00184--RING
SM00165--UBA

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0005509--F:calcium ion binding
GO:0004871--F:signal transducer activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007166--P:cell surface receptor signaling pathway
GO:0023051--P:regulation of signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001412	Ailuropoda melanoleuca	88.53	0.00e+00	1505.00
IUUC-Apl-004148	Anas platyrhynchos	79.28	0.00e+00	1343.00
IUUC-Aca-005204	Anolis carolinensis	75.58	0.00e+00	1285.00
IUUC-Ame-011919	Astyanax mexicanus	61.48	0.00e+00	1000.00
IUUC-Bta-013044	Bos taurus	88.83	0.00e+00	1511.00
IUUC-Cja-018813	Callithrix jacchus	86.07	0.00e+00	1516.00
IUUC-Cfa-021054	Canis familiaris	88.43	0.00e+00	1545.00
IUUC-Cpo-022514	Cavia porcellus	85.69	0.00e+00	1509.00
IUUC-Csa-024110	Chlorocebus sabaeus	90.35	0.00e+00	1571.00
IUUC-Cho-024886	Choloepus hoffmanni	70.70	0.00e+00	980.00
IUUC-Dre-027480	Danio rerio	85.51	0.00e+00	881.00
IUUC-Dno-028923	Dasypus novemcinctus	88.53	0.00e+00	1509.00
IUUC-Dor-031040	Dipodomys ordii	89.98	0.00e+00	811.00
IUUC-Ete-032406	Echinops telfairi	83.53	0.00e+00	1378.00
IUUC-Eca-033849	Equus caballus	87.82	0.00e+00	1524.00
IUUC-Fca-036224	Felis catus	88.64	0.00e+00	1515.00
IUUC-Fal-036860	Ficedula albicollis	95.96	0.00e+00	1007.00
IUUC-Gga-040159	Gallus gallus	76.24	0.00e+00	1306.00
IUUC-Gac-042312	Gasterosteus aculeatus	85.02	0.00e+00	876.00
IUUC-Hsa-046306	Homo sapiens	90.65	0.00e+00	1575.00
IUUC-Lch-049931	Latimeria chalumnae	60.32	0.00e+00	837.00
IUUC-Loc-052524	Lepisosteus oculatus	88.98	0.00e+00	906.00
IUUC-Laf-053635	Loxodonta africana	84.69	0.00e+00	1454.00
IUUC-Mcc-055536	Macaca mulatta	90.24	0.00e+00	1569.00
IUUC-Meu-056045	Macropus eugenii	71.89	0.00e+00	1144.00
IUUC-Mga-060177	Meleagris gallopavo	82.06	0.00e+00	987.00
IUUC-Mmr-061088	Microcebus murinus	89.34	0.00e+00	1541.00
IUUC-Mdo-062020	Monodelphis domestica	83.40	0.00e+00	1426.00
IUUC-Mmu-063114	Mus musculus	83.55	0.00e+00	1447.00
IUUC-Mpu-066632	Mustela putorius furo	89.04	0.00e+00	1548.00
IUUC-Mlu-067145	Myotis lucifugus	88.63	0.00e+00	1532.00
IUUC-Ont-072323	Oreochromis niloticus	83.55	0.00e+00	879.00
IUUC-Oan-073165	Ornithorhynchus anatinus	82.57	0.00e+00	1452.00
IUUC-Ocu-074723	Oryctolagus cuniculus	88.53	0.00e+00	1536.00
IUUC-Oga-088021	Otolemur garnettii	87.93	0.00e+00	1514.00
IUUC-Oar-089809	Ovis aries	88.63	0.00e+00	1512.00
IUUC-Ptr-090834	Pan troglodytes	90.65	0.00e+00	1574.00
IUUC-Pan-092225	Papio anubis	90.24	0.00e+00	1571.00
IUUC-Psi-093317	Pelodiscus sinensis	79.47	0.00e+00	1383.00
IUUC-Pma-094249	Petromyzon marinus	77.61	6.00e-127	446.00
IUUC-Pab-097595	Pongo abelii	90.45	0.00e+00	1571.00
IUUC-Pca-100844	Procavia capensis	71.88	0.00e+00	1161.00
IUUC-Pva-103216	Pteropus vampyrus	99.81	0.00e+00	1058.00
IUUC-Rno-105381	Rattus norvegicus	87.92	0.00e+00	1536.00
IUUC-Sha-107574	Sarcophilus harrisii	83.66	0.00e+00	1426.00
IUUC-Sar-113500	Sorex araneus	76.20	0.00e+00	1208.00
IUUC-Ssc-115856	Sus scrofa	86.65	0.00e+00	1286.00
IUUC-Tgu-116866	Taeniopygia guttata	79.96	0.00e+00	1344.00
IUUC-Tru-118579	Takifugu rubripes	86.53	0.00e+00	883.00
IUUC-Tsy-119167	Tarsius syrichta	76.76	0.00e+00	1259.00
IUUC-Tni-120788	Tetraodon nigroviridis	85.23	0.00e+00	892.00
IUUC-Tbe-127830	Tupaia belangeri	81.21	0.00e+00	1005.00
IUUC-Ttr-128631	Tursiops truncatus	89.24	0.00e+00	1548.00
IUUC-Vpa-130713	Vicugna pacos	86.41	0.00e+00	1306.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence