iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-073165

UUCD1 version

UUC-OrA-00056

Ensembl Protein ID

ENSOANP00000011939.3

UniProt Accession

F6QKN5; F6QKN5_ORNAN

Protein Name

Uncharacterized protein

Gene Name

CBLB

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000007499.3	ENSOANT00000011941.3	ENSOANP00000011939.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.00e-07	32.6	373	412

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC e  kd +++ pCgH+++++Cl +w    ++s ++  CP Cr
   Q: 373  CKICAENDKD-VKIEPCGHLMCTSCLTAW----QESDGQ-GCPFCR 412
           99********.******************....555555.5****8 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MANSTNGRNP GGRGGNPRKG RILGIIDAIQ DAVGPPKQAA ADRRTVEKTW KLMDKVVRLC 60
QNPKLQLKNS PPYILDILPD TYQHLRLILS KYDDNQKLAQ LSENEYFKIY IDSLMKKSKR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTTTCTTTC CCTCCCCTGA CGCACACGCG CCTCGTGCGT TTTCTCAGAG CGGAGATCCC 60
AGATGGCCAA CTCCACGAAT GGCCGGAACC CAGGGGGCCG AGGAGGAAAC CCCCGCAAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR024162--Adaptor_Cbl
IPR014741--Adaptor_Cbl_EF_hand-like
IPR003153--Adaptor_Cbl_N_hlx
IPR014742--Adaptor_Cbl_SH2-like
IPR024159--Cbl_PTB
IPR011992--EF-hand-dom_pair
IPR000980--SH2
IPR015940--UBA
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51506--CBL_PTB
PS50030--UBA
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02262--Cbl_N
PF02761--Cbl_N2
PF02762--Cbl_N3

SMART

SM00184--RING
SM00165--UBA

Gene Ontology

GO:0005829--C:cytosol
GO:0045121--C:membrane raft
GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0005509--F:calcium ion binding
GO:0030971--F:receptor tyrosine kinase binding
GO:0017124--F:SH3 domain binding
GO:0004871--F:signal transducer activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007173--P:epidermal growth factor receptor signaling pathway
GO:0007175--P:negative regulation of epidermal growth factor-activated receptor activity
GO:0006508--P:proteolysis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001412	Ailuropoda melanoleuca	89.44	0.00e+00	1548.00
IUUC-Apl-004148	Anas platyrhynchos	87.11	0.00e+00	1514.00
IUUC-Aca-005204	Anolis carolinensis	83.11	0.00e+00	1482.00
IUUC-Ame-011919	Astyanax mexicanus	64.54	0.00e+00	1040.00
IUUC-Bta-013044	Bos taurus	89.54	0.00e+00	1547.00
IUUC-Cel-018674	Caenorhabditis elegans	56.92	4.00e-134	471.00
IUUC-Cja-018813	Callithrix jacchus	82.93	0.00e+00	1449.00
IUUC-Cfa-021054	Canis familiaris	89.44	0.00e+00	1608.00
IUUC-Cpo-022514	Cavia porcellus	85.58	0.00e+00	1568.00
IUUC-Csa-024110	Chlorocebus sabaeus	89.64	0.00e+00	1574.00
IUUC-Cho-024886	Choloepus hoffmanni	73.49	0.00e+00	1048.00
IUUC-Cin-025574	Ciona intestinalis	67.89	2.00e-173	601.00
IUUC-Csv-025938	Ciona savignyi	67.42	2.00e-166	577.00
IUUC-Cme-027206	Cyanidioschyzon merolae	30.19	7.00e-04	37.40
IUUC-Dre-027480	Danio rerio	65.71	0.00e+00	1047.00
IUUC-Dno-028923	Dasypus novemcinctus	89.34	0.00e+00	1548.00
IUUC-Dor-031040	Dipodomys ordii	88.70	0.00e+00	800.00
IUUC-Dme-032213	Drosophila melanogaster	72.43	0.00e+00	641.00
IUUC-Ete-032406	Echinops telfairi	84.93	0.00e+00	1433.00
IUUC-Eca-033849	Equus caballus	88.83	0.00e+00	1575.00
IUUC-Eeu-035142	Erinaceus europaeus	64.95	1.00e-170	592.00
IUUC-Fca-036224	Felis catus	89.66	0.00e+00	1579.00
IUUC-Fal-036860	Ficedula albicollis	98.25	0.00e+00	1017.00
IUUC-Gmo-038698	Gadus morhua	75.21	0.00e+00	741.00
IUUC-Gga-040159	Gallus gallus	83.18	0.00e+00	1468.00
IUUC-Gac-042312	Gasterosteus aculeatus	84.73	0.00e+00	889.00
IUUC-Ggo-045175	Gorilla gorilla	82.57	0.00e+00	1437.00
IUUC-Hsa-046306	Homo sapiens	89.64	0.00e+00	1573.00
IUUC-Itr-048795	Ictidomys tridecemlineatus	77.06	5.00e-174	603.00
IUUC-Lch-049931	Latimeria chalumnae	61.54	0.00e+00	896.00
IUUC-Loc-052524	Lepisosteus oculatus	69.91	0.00e+00	1119.00
IUUC-Laf-053635	Loxodonta africana	86.11	0.00e+00	1492.00
IUUC-Mcc-055536	Macaca mulatta	89.64	0.00e+00	1572.00
IUUC-Meu-056045	Macropus eugenii	77.70	0.00e+00	1269.00
IUUC-Mga-060177	Meleagris gallopavo	93.64	0.00e+00	1135.00
IUUC-Mmr-061088	Microcebus murinus	89.85	0.00e+00	1578.00
IUUC-Mdo-062020	Monodelphis domestica	90.35	0.00e+00	1564.00
IUUC-Mmu-063114	Mus musculus	84.37	0.00e+00	1503.00
IUUC-Mpu-066632	Mustela putorius furo	89.85	0.00e+00	1605.00
IUUC-Mlu-067145	Myotis lucifugus	89.54	0.00e+00	1571.00
IUUC-Nle-069285	Nomascus leucogenys	84.81	0.00e+00	728.00
IUUC-Opr-071026	Ochotona princeps	75.91	0.00e+00	718.00
IUUC-Ont-072323	Oreochromis niloticus	73.43	0.00e+00	897.00
IUUC-Ocu-074723	Oryctolagus cuniculus	89.54	0.00e+00	1579.00
IUUC-Ola-087165	Oryzias latipes	81.60	0.00e+00	741.00
IUUC-Oga-088021	Otolemur garnettii	88.03	0.00e+00	1546.00
IUUC-Oar-089809	Ovis aries	89.44	0.00e+00	1552.00
IUUC-Ptr-090834	Pan troglodytes	89.54	0.00e+00	1570.00
IUUC-Pan-092225	Papio anubis	89.75	0.00e+00	1577.00
IUUC-Psi-093317	Pelodiscus sinensis	87.06	0.00e+00	1603.00
IUUC-Pma-094249	Petromyzon marinus	77.99	8.00e-128	448.00
IUUC-Pfo-096049	Poecilia formosa	70.78	0.00e+00	731.00
IUUC-Pab-097595	Pongo abelii	89.85	0.00e+00	1577.00
IUUC-Pca-100844	Procavia capensis	76.92	0.00e+00	1130.00
IUUC-Pva-103216	Pteropus vampyrus	83.45	0.00e+00	1481.00
IUUC-Rno-105381	Rattus norvegicus	87.82	0.00e+00	1578.00
IUUC-Sha-107574	Sarcophilus harrisii	90.26	0.00e+00	1571.00
IUUC-Sar-113500	Sorex araneus	78.59	0.00e+00	1293.00
IUUC-Ssc-115856	Sus scrofa	88.41	0.00e+00	1337.00
IUUC-Tgu-116866	Taeniopygia guttata	85.33	0.00e+00	1493.00
IUUC-Tru-118579	Takifugu rubripes	85.77	0.00e+00	885.00
IUUC-Tsy-119167	Tarsius syrichta	85.12	0.00e+00	1048.00
IUUC-Tni-120788	Tetraodon nigroviridis	85.47	0.00e+00	897.00
IUUC-Tbe-127830	Tupaia belangeri	90.58	0.00e+00	1124.00
IUUC-Ttr-128631	Tursiops truncatus	90.05	0.00e+00	1582.00
IUUC-Vpa-130713	Vicugna pacos	89.64	0.00e+00	1379.00
IUUC-Xtr-131926	Xenopus tropicalis	92.82	0.00e+00	994.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence