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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Rno-105384
UUCD1 version UUC-RaN-01090
Ensembl Protein ID ENSRNOP00000069266.1
UniProt Accession A0A0G2JUX4; A0A0G2JUX4_RAT
Genbank Protein ID ENSRNOP00000069266
Protein Name Ubiquitin-specific peptidase 47
Genbank Nucleotide ID AABR07005036
Gene Name Usp47
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSRNOG00000026754.6 ENSRNOT00000065712.2 ENSRNOP00000058846.1
ENSRNOG00000026754.6 ENSRNOT00000087461.1 ENSRNOP00000069266.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
RAID2
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 1.80e-75 254.6 188 562
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           +Gl N+  tCY+NS+LQ+L+++pe+r++l +    +++e++ ++p +++  +lq+lf  l++skk+a++++++++++++ ++e    +q
   Q: 188  VGLVNQAMTCYLNSLLQTLFMTPEFRNALYK---WEFEESE-EDPVTSIPYQLQRLFVLLQTSKKRAIETTDVTRSFGWDSSE--AWQQ 270
           6******************************...5555443.5899*********************************9998..9*** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           +D+qE++++++d+le++                           k++++ +li++l+qg+lk+ ++clec+ +  r ++ ld++l ++ 
   Q: 271  HDVQELCRVMFDALEQKW--------------------------KQTEQADLINELYQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRP 333
           ******************..........................678999*************************************95 PP
   S: 179  ke.etkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfct 266
              +++  s++++L++f ++e l+g n+y+ce+ckkk++a+k l++ ++P  L+l+LkRf f+ ++++r+k+n++++fp+eLd+s f  
   Q: 334  YGsSQAFASVEEALHAFIQPEILDGPNQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMSFPEELDMSTFID 422
           54045678******************************************************************************998 PP
   S: 267  speekqke.....................................................kkkYeLiavvvHsGslssGHYvayvkn. 301
            ++ek+ +                                                     +  YeL++v+vHsGs+ +GHY+a++k+ 
   Q: 423  IEDEKSPQtesctdsgaenegschsdqmsndfstddavdegiclesstgsekiskpgleknSLMYELFSVMVHSGSAAGGHYYACIKSf 511
           86666666788888888889999999999999999999999999999999999999999999**************************5 PP
   S: 302  ekgkWllfdDskVtevkeeevleetg................staYvlfYk 336
           ++++W+ f+D++V+ +++e++++++g                ++aY+l+Y+
   Q: 512  SDDQWYSFNDQHVSRITQEDIKKTHGgssgsrgyyssafassTNAYMLIYR 562
           5666*******************888************************8 PP
   
Organism Rattus norvegicus
Protein Sequence
(Fasta)
MVPGEENQLV PKEDVFWRCR QNIFDEMKKK FLQIENAAEE PRVLCIIQDT TNSKTVNERI 60
TVNLPASTPV RKLFEDVANK VGYINGTFDL TWGNGINTAD LAPLDHTSDK SLLDANFEPG 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Rno-105384|DUB,USP|Rattus norvegicus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CGGGGCAGAG CAAGAGGTGA GAAGATCCCG AGCTCGCCAC GGCAGCACAC GTTCCTCAGG 60
CCAGGCGCCG GGCCGCGCGC CCACTGAGCT GAATTCTCGC GAGAGCGGCA GCCGCCATTT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Rno-105384|DUB,USP|Rattus norvegicus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR018200--USP_CS
IPR028889--USP_dom
PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
Pfam

PF00443--UCH
Gene Ontology

GO:0005737--C:cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0006284--P:base-excision repair
GO:0034644--P:cellular response to UV
GO:0035520--P:monoubiquitinated protein deubiquitination
GO:0043154--P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0010972--P:negative regulation of G2/M transition of mitotic cell cycle
GO:1902230--P:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0030307--P:positive regulation of cell growth
GO:0042981--P:regulation of apoptotic process
GO:0042493--P:response to drug
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002228 Ailuropoda melanoleuca 94.04 0.00e+00 2487.00
IUUC-Apl-003486 Anas platyrhynchos 88.55 0.00e+00 2326.00
IUUC-Aca-005061 Anolis carolinensis 86.92 0.00e+00 2373.00
IUUC-Ame-011206 Astyanax mexicanus 80.09 0.00e+00 2108.00
IUUC-Bta-012942 Bos taurus 94.68 0.00e+00 2532.00
IUUC-Cel-018600 Caenorhabditis elegans 37.50 4.00e-122 433.00
IUUC-Cja-018950 Callithrix jacchus 95.92 0.00e+00 2335.00
IUUC-Cfa-020299 Canis familiaris 95.85 0.00e+00 2504.00
IUUC-Cpo-021943 Cavia porcellus 95.59 0.00e+00 2513.00
IUUC-Csa-023285 Chlorocebus sabaeus 94.40 0.00e+00 2484.00
IUUC-Cho-025006 Choloepus hoffmanni 87.33 0.00e+00 2150.00
IUUC-Cin-025145 Ciona intestinalis 41.73 0.00e+00 730.00
IUUC-Csv-025839 Ciona savignyi 50.08 1.00e-165 577.00
IUUC-Dre-027959 Danio rerio 80.13 0.00e+00 2074.00
IUUC-Dno-030023 Dasypus novemcinctus 92.51 0.00e+00 2391.00
IUUC-Dor-030994 Dipodomys ordii 96.20 0.00e+00 951.00
IUUC-Dme-031604 Drosophila melanogaster 49.57 9.00e-147 515.00
IUUC-Ete-032596 Echinops telfairi 78.95 0.00e+00 1280.00
IUUC-Eca-033913 Equus caballus 95.45 0.00e+00 2528.00
IUUC-Eeu-034518 Erinaceus europaeus 88.07 0.00e+00 2103.00
IUUC-Fca-035997 Felis catus 95.12 0.00e+00 2527.00
IUUC-Fal-037088 Ficedula albicollis 87.71 0.00e+00 2067.00
IUUC-Gmo-038920 Gadus morhua 77.22 0.00e+00 2020.00
IUUC-Gga-040953 Gallus gallus 87.43 0.00e+00 2337.00
IUUC-Gac-042400 Gasterosteus aculeatus 78.70 0.00e+00 2053.00
IUUC-Ggo-044820 Gorilla gorilla 93.16 0.00e+00 2422.00
IUUC-Hsa-046634 Homo sapiens 95.71 0.00e+00 2534.00
IUUC-Lch-050440 Latimeria chalumnae 85.24 0.00e+00 2306.00
IUUC-Loc-051904 Lepisosteus oculatus 83.64 0.00e+00 2231.00
IUUC-Laf-053760 Loxodonta africana 94.40 0.00e+00 2559.00
IUUC-Mcc-054637 Macaca mulatta 95.85 0.00e+00 2541.00
IUUC-Meu-056904 Macropus eugenii 93.74 0.00e+00 1667.00
IUUC-Mga-059556 Meleagris gallopavo 86.87 0.00e+00 2302.00
IUUC-Mmr-061192 Microcebus murinus 96.22 0.00e+00 2550.00
IUUC-Mdo-061929 Monodelphis domestica 93.67 0.00e+00 2502.00
IUUC-Mmu-063726 Mus musculus 97.82 0.00e+00 2625.00
IUUC-Mpu-066014 Mustela putorius furo 95.68 0.00e+00 2489.00
IUUC-Mlu-067232 Myotis lucifugus 95.17 0.00e+00 2503.00
IUUC-Nle-069619 Nomascus leucogenys 94.25 0.00e+00 2480.00
IUUC-Opr-070224 Ochotona princeps 92.05 0.00e+00 1131.00
IUUC-Ont-071384 Oreochromis niloticus 80.16 0.00e+00 2097.00
IUUC-Oan-073208 Ornithorhynchus anatinus 87.42 0.00e+00 2363.00
IUUC-Ocu-074285 Oryctolagus cuniculus 95.85 0.00e+00 2541.00
IUUC-Ola-087051 Oryzias latipes 78.45 0.00e+00 2007.00
IUUC-Oga-088928 Otolemur garnettii 95.74 0.00e+00 2516.00
IUUC-Oar-090215 Ovis aries 95.10 0.00e+00 2531.00
IUUC-Ptr-091035 Pan troglodytes 95.71 0.00e+00 2537.00
IUUC-Pan-092377 Papio anubis 95.30 0.00e+00 2490.00
IUUC-Pfo-096722 Poecilia formosa 79.60 0.00e+00 2075.00
IUUC-Pab-098723 Pongo abelii 95.56 0.00e+00 2534.00
IUUC-Pca-100105 Procavia capensis 90.23 0.00e+00 2310.00
IUUC-Pva-102514 Pteropus vampyrus 96.04 0.00e+00 939.00
IUUC-Sha-106982 Sarcophilus harrisii 90.18 0.00e+00 2449.00
IUUC-Sar-113723 Sorex araneus 84.60 0.00e+00 917.00
IUUC-Ssc-115671 Sus scrofa 95.30 0.00e+00 2009.00
IUUC-Tgu-116722 Taeniopygia guttata 86.73 0.00e+00 2284.00
IUUC-Tru-118380 Takifugu rubripes 77.38 0.00e+00 2073.00
IUUC-Tsy-119646 Tarsius syrichta 89.43 0.00e+00 2307.00
IUUC-Tni-120762 Tetraodon nigroviridis 78.06 0.00e+00 2089.00
IUUC-Tbe-127861 Tupaia belangeri 93.49 0.00e+00 2328.00
IUUC-Ttr-129254 Tursiops truncatus 89.59 0.00e+00 1422.00
IUUC-Vpa-130141 Vicugna pacos 96.35 0.00e+00 1172.00
IUUC-Xtr-132700 Xenopus tropicalis 81.23 0.00e+00 2182.00
Created Date 25-Jun-2017

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