iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-027548

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin-specific peptidase 12b

Genbank Nucleotide ID

CR381676

Gene Name

usp12b

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000074367.4	ENSDART00000114429.4	ENSDARP00000099592.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.70e-97	326.9	39	381

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgy 87
           +Gl N+gNtCY+NSvLQ+L++++++re +l     k++    + +k++ll++l++lf+++   k+k +++ p+++++ l+ke+e f++y
   Q: 39   FGLVNFGNTCYCNSVLQALYFCRPFREKVLA---YKIQ----PRRKESLLTCLADLFNSIAtqKKKVGVIPPKKFISRLRKENELFDNY 120
           6******************************...5555....45789*************976777779******************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde...............aeekkkkknkslisdlFqgqlksqikclecdn 161
           +qqDa+Efl++ll+++ + l++ek++++++  +  +     +               + e ++k ++++++++Fqg+l+++++cl+c+ 
   Q: 121  MQQDAHEFLNYLLNTIADLLQEEKSQERQQNGKVVQ-----NggsgsggggsgsstgEGETEEKTQQTWVHEIFQGTLTNETRCLNCEA 204
           ********************5533333333333332.....1456679********9999999999*********************** PP
   S: 162  vssreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekin 250
           vss++e+fldls++v++++     s+++cL+ f+++e+l++e kyyce+c++kqea+k++++kklP +L lhLkRf++  + ++ +k++
   Q: 205  VSSKDEDFLDLSVDVEQNT-----SITHCLRGFSNTETLCSEYKYYCEQCRSKQEAQKRMRVKKLPMILALHLKRFKYMDQLHRYTKLS 288
           *******************.....9**************************************************************** PP
   S: 251  kkvefpleLdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetg.........st 329
            +v fpleL l  f+ts +   + ++ Y+L+avvvH G +++ GHY+++vk+ +g WllfdD+ V++++ + ++e+ g         ++
   Q: 289  YRVVFPLELRL--FNTSGDA-TNPDRLYDLVAVVVHCGsGPNRGHYITIVKS-HGFWLLFDDDIVEKIDAQAIEEFYGltsdisknsES 373
           ******66665..7777444.4469***************************.888*******************999*********** PP
   S: 330  aYvlfYkr 337
           +Y+lfY++
   Q: 374  GYILFYQS 381
           ******97 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MEILMTVRKI ASICTMGANA SALEKEIGPE QFPVNEHYFG LVNFGNTCYC NSVLQALYFC 60
RPFREKVLAY KIQPRRKESL LTCLADLFNS IATQKKKVGV IPPKKFISRL RKENELFDNY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTGCTGGAC CGACTGAAGG ATTCACCGGA ACTCCAGCCC GTGCGGCTGT CACACTTTTA 60
AATAGGGGTT CGGTCCAATA TGGCGGCAGA CGGATGGAAA TACTGATGAC AGTCCGAAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

dre:559878

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003733	Anas platyrhynchos	87.21	0.00e+00	665.00
IUUC-Aca-005054	Anolis carolinensis	89.56	0.00e+00	686.00
IUUC-Ame-011132	Astyanax mexicanus	95.35	0.00e+00	739.00
IUUC-Fal-037172	Ficedula albicollis	88.77	0.00e+00	679.00
IUUC-Gga-041044	Gallus gallus	89.82	0.00e+00	690.00
IUUC-Lch-050237	Latimeria chalumnae	89.30	0.00e+00	684.00
IUUC-Loc-052559	Lepisosteus oculatus	90.70	0.00e+00	720.00
IUUC-Mga-059602	Meleagris gallopavo	90.03	0.00e+00	665.00
IUUC-Ont-072049	Oreochromis niloticus	93.62	0.00e+00	739.00
IUUC-Psi-093379	Pelodiscus sinensis	90.34	0.00e+00	692.00
IUUC-Pfo-097041	Poecilia formosa	92.63	0.00e+00	712.00
IUUC-Tgu-116825	Taeniopygia guttata	89.03	0.00e+00	684.00
IUUC-Tru-118379	Takifugu rubripes	95.04	0.00e+00	741.00
IUUC-Xtr-132082	Xenopus tropicalis	90.34	0.00e+00	710.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence