iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.70e-28	96.1	100	134
UBD/Beta-Prp	3.40e-44	151.2	13	134

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           H+++v+c++f  d  + +sG++D+ +++WD+rt +
   Q: 100  HAGGVRCVCFnEDsSIAISGGRDNAVMCWDIRTRR 134
           99********8445899*************99865 PP

UBD/Beta-Prp

   S: 133  lsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrf 230
            + ++g+v+ v+++ dg ++ s++ D++++lW+ ++g ll+t  g h d v+  + + ++ ++vs+sld+++++wd++tg  vr+l+ h   v++v f
   Q: 13   IDCKQGAVRAVRYNVDGTYCLSCGSDKKIKLWNPASGLLLKTYGG-HADEVTDAAGSCDSSYIVSASLDKSIIYWDVSTGAPVRRLRSHAGGVRCVCF 109
           5567899************************************88.**************************************************** PP
   S: 231  spnderlvsgssDgsiriWdlrsgd 255
            +++ + +sg+ D+ + +Wd+r++ 
   Q: 110  NEDSSIAISGGRDNAVMCWDIRTRR 134
           **********************986 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MPEFENFNVK TTIDCKQGAV RAVRYNVDGT YCLSCGSDKK IKLWNPASGL LLKTYGGHAD 60
EVTDAAGSCD SSYIVSASLD KSIIYWDVST GAPVRRLRSH AGGVRCVCFN EDSSIAISGG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACTGTCCGT TTGTTTATAT TTTTCGTGCT GCAGTTGTGT TATTGTTTTT AATACAAATA 60
TGCCGGAATT TGAGAACTTT AACGTAAAAA CCACAATTGA CTGCAAACAA GGTGCAGTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0071011--C:precatalytic spliceosome
GO:0032947--F:protein complex scaffold
GO:0000398--P:mRNA splicing, via spliceosome

KEGG

dme:Dmel_CG4935

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002160	Ailuropoda melanoleuca	47.92	6.00e-77	280.00
IUUC-Atr-002647	Amborella trichopoda	41.70	1.00e-61	228.00
IUUC-Aca-004948	Anolis carolinensis	46.10	6.00e-78	283.00
IUUC-Aly-006489	Arabidopsis lyrata	41.33	2.00e-58	218.00
IUUC-Ath-007099	Arabidopsis thaliana	41.70	7.00e-59	219.00
IUUC-Acl-008374	Aspergillus clavatus	29.93	5.00e-30	124.00
IUUC-Afl-008506	Aspergillus flavus	29.17	2.00e-30	125.00
IUUC-Ang-009705	Aspergillus niger	28.81	6.00e-30	124.00
IUUC-Aor-010031	Aspergillus oryzae	29.17	2.00e-30	125.00
IUUC-Ame-011056	Astyanax mexicanus	43.94	3.00e-72	264.00
IUUC-Bgr-012109	Blumeria graminis	33.45	6.00e-40	157.00
IUUC-Bta-012476	Bos taurus	47.22	2.00e-76	278.00
IUUC-Bci-013860	Botrytis cinerea	31.51	3.00e-34	138.00
IUUC-Bdi-014565	Brachypodium distachyon	40.22	9.00e-63	232.00
IUUC-Bol-016204	Brassica oleracea	40.96	7.00e-58	216.00
IUUC-Bra-018093	Brassica rapa	40.96	6.00e-58	216.00
IUUC-Cel-018500	Caenorhabditis elegans	42.81	6.00e-70	256.00
IUUC-Cja-019279	Callithrix jacchus	48.56	2.00e-76	278.00
IUUC-Cfa-020516	Canis familiaris	47.57	1.00e-76	278.00
IUUC-Cpo-021427	Cavia porcellus	46.88	3.00e-73	267.00
IUUC-Cre-022775	Chlamydomonas reinhardtii	42.34	1.00e-60	226.00
IUUC-Csa-023449	Chlorocebus sabaeus	48.20	1.00e-76	278.00
IUUC-Cin-025637	Ciona intestinalis	43.88	2.00e-77	281.00
IUUC-Cgl-026458	Colletotrichum gloeosporioides	31.02	1.00e-35	142.00
IUUC-Cne-026994	Cryptococcus neoformans	35.34	4.00e-47	180.00
IUUC-Dre-028239	Danio rerio	44.29	2.00e-73	268.00
IUUC-Dno-029408	Dasypus novemcinctus	45.83	2.00e-74	271.00
IUUC-Dor-030684	Dipodomys ordii	40.86	2.00e-39	155.00
IUUC-Dse-031344	Dothistroma septosporum	31.64	2.00e-34	138.00
IUUC-Ete-033126	Echinops telfairi	42.71	2.00e-65	241.00
IUUC-Eca-034356	Equus caballus	43.40	3.00e-62	231.00
IUUC-Eeu-035196	Erinaceus europaeus	50.67	4.00e-43	167.00
IUUC-Fca-036231	Felis catus	47.92	1.00e-76	278.00
IUUC-Fox-038076	Fusarium oxysporum	32.62	4.00e-39	154.00
IUUC-Fso-038093	Fusarium solani	31.94	5.00e-35	140.00
IUUC-Gmo-039056	Gadus morhua	43.20	1.00e-68	252.00
IUUC-Ggr-039981	Gaeumannomyces graminis	31.62	3.00e-26	112.00
IUUC-Gga-041042	Gallus gallus	47.92	5.00e-77	280.00
IUUC-Gac-042638	Gasterosteus aculeatus	45.67	1.00e-72	265.00
IUUC-Gma-042723	Glycine max	41.33	1.00e-62	231.00
IUUC-Ggo-044720	Gorilla gorilla	48.20	2.00e-76	278.00
IUUC-Hsa-046056	Homo sapiens	48.56	7.00e-77	279.00
IUUC-Hvu-047675	Hordeum vulgare	36.48	4.00e-58	217.00
IUUC-Itr-048733	Ictidomys tridecemlineatus	48.61	8.00e-78	282.00
IUUC-Lch-050634	Latimeria chalumnae	44.91	3.00e-70	257.00
IUUC-Lpe-051470	Leersia perrieri	40.73	2.00e-62	231.00
IUUC-Loc-052452	Lepisosteus oculatus	46.40	9.00e-74	269.00
IUUC-Lma-053235	Leptosphaeria maculans	34.55	1.00e-16	79.70
IUUC-Laf-054315	Loxodonta africana	48.92	2.00e-77	281.00
IUUC-Mcc-054923	Macaca mulatta	47.48	9.00e-76	275.00
IUUC-Mor-056936	Magnaporthe oryzae	28.87	3.00e-26	111.00
IUUC-Mtr-058595	Medicago truncatula	40.59	1.00e-62	232.00
IUUC-Mla-058902	Melampsora laricipopulina	35.54	6.00e-48	183.00
IUUC-Mvi-060471	Microbotryum violaceum	36.17	4.00e-54	204.00
IUUC-Mmr-061665	Microcebus murinus	47.57	1.00e-76	278.00
IUUC-Mdo-062750	Monodelphis domestica	45.16	4.00e-69	253.00
IUUC-Mmu-063750	Mus musculus	48.26	8.00e-78	282.00
IUUC-Mac-065441	Musa acuminata	40.22	4.00e-60	223.00
IUUC-Mpu-066863	Mustela putorius furo	47.92	5.00e-77	280.00
IUUC-Mlu-067645	Myotis lucifugus	48.20	5.00e-76	276.00
IUUC-Nfi-068549	Neosartorya fischeri	28.75	7.00e-28	117.00
IUUC-Ncr-068816	Neurospora crassa	31.30	4.00e-23	101.00
IUUC-Nle-069457	Nomascus leucogenys	48.20	2.00e-76	278.00
IUUC-Ont-071674	Oreochromis niloticus	45.76	1.00e-69	255.00
IUUC-Oan-073391	Ornithorhynchus anatinus	46.44	3.00e-79	287.00
IUUC-Ocu-074186	Oryctolagus cuniculus	46.53	1.00e-72	265.00
IUUC-Oba-075414	Oryza barthii	41.85	2.00e-62	231.00
IUUC-Obr-076739	Oryza brachyantha	40.96	9.00e-63	232.00
IUUC-Ogl-076962	Oryza glaberrima	41.70	1.00e-62	232.00
IUUC-Ogu-078831	Oryza glumaepatula	41.70	1.00e-62	232.00
IUUC-Oin-079985	Oryza indica	41.33	2.00e-62	231.00
IUUC-Ome-081333	Oryza meridionalis	41.60	1.00e-59	222.00
IUUC-Oni-082558	Oryza nivara	41.33	2.00e-62	231.00
IUUC-Opu-084091	Oryza punctata	41.70	1.00e-63	235.00
IUUC-Oru-085253	Oryza rufipogon	40.46	8.00e-59	219.00
IUUC-Osa-086077	Oryza sativa	41.33	2.00e-62	231.00
IUUC-Ola-086946	Oryzias latipes	44.26	3.00e-72	264.00
IUUC-Olu-087604	Ostreococcus lucimarinus	37.19	5.00e-47	180.00
IUUC-Oga-088681	Otolemur garnettii	47.57	1.00e-77	282.00
IUUC-Oar-089913	Ovis aries	46.88	4.00e-76	277.00
IUUC-Ptr-091343	Pan troglodytes	48.20	1.00e-76	279.00
IUUC-Pan-092078	Papio anubis	48.20	1.00e-76	278.00
IUUC-Psi-093190	Pelodiscus sinensis	44.07	1.00e-77	281.00
IUUC-Pno-095078	Phaeosphaeria nodorum	34.03	1.00e-36	146.00
IUUC-Ppa-095777	Physcomitrella patens	42.44	9.00e-65	239.00
IUUC-Pfo-097153	Poecilia formosa	45.80	3.00e-72	264.00
IUUC-Pab-098307	Pongo abelii	48.03	5.00e-75	273.00
IUUC-Pop-099315	Populus trichocarpa	41.03	6.00e-58	216.00
IUUC-Pca-100538	Procavia capensis	46.56	2.00e-67	248.00
IUUC-Ppe-101632	Prunus persica	39.85	3.00e-61	227.00
IUUC-Pva-102484	Pteropus vampyrus	46.88	6.00e-76	276.00
IUUC-Pgr-103495	Puccinia graminis	33.83	9.00e-50	189.00
IUUC-Ptt-103975	Puccinia triticina	32.71	1.00e-48	186.00
IUUC-Pte-104354	Pyrenophora teres	31.00	9.00e-27	113.00
IUUC-Pyt-104692	Pyrenophora triticirepentis	31.00	2.00e-26	112.00
IUUC-Rno-105655	Rattus norvegicus	48.61	8.00e-78	282.00
IUUC-Sha-107130	Sarcophilus harrisii	39.42	1.00e-47	182.00
IUUC-Sja-107933	Schizosaccharomyces japonicus	32.14	2.00e-44	171.00
IUUC-Spo-108131	Schizosaccharomyces pombe	31.72	5.00e-41	160.00
IUUC-Ssl-108405	Sclerotinia sclerotiorum	32.20	1.00e-35	142.00
IUUC-Smo-109004	Selaginella moellendorffii	40.96	5.00e-55	206.00
IUUC-Sit-110508	Setaria italica	42.07	2.00e-63	234.00
IUUC-Sly-111093	Solanum lycopersicum	40.00	2.00e-54	204.00
IUUC-Stu-112380	Solanum tuberosum	40.00	2.00e-54	204.00
IUUC-Sar-113127	Sorex araneus	40.29	3.00e-25	108.00
IUUC-Sbi-114461	Sorghum bicolor	41.70	8.00e-63	232.00
IUUC-Sre-115020	Sporisorium reilianum	30.32	5.00e-28	118.00
IUUC-Ssc-115632	Sus scrofa	47.57	2.00e-76	278.00
IUUC-Tru-118039	Takifugu rubripes	45.33	2.00e-71	261.00
IUUC-Tsy-119239	Tarsius syrichta	51.88	3.00e-47	181.00
IUUC-Tni-120097	Tetraodon nigroviridis	44.81	3.00e-68	251.00
IUUC-Tca-121695	Theobroma cacao	41.73	2.00e-63	234.00
IUUC-Tre-122182	Trichoderma reesei	32.43	1.00e-33	136.00
IUUC-Tvi-122429	Trichoderma virens	31.58	5.00e-37	147.00
IUUC-Tae-125136	Triticum aestivum	40.58	2.00e-63	234.00
IUUC-Tur-126216	Triticum urartu	40.58	3.00e-63	234.00
IUUC-Tme-127030	Tuber melanosporum	37.36	1.00e-48	185.00
IUUC-Tbe-127686	Tupaia belangeri	49.72	8.00e-49	186.00
IUUC-Ttr-128770	Tursiops truncatus	46.18	4.00e-74	270.00
IUUC-Uma-129446	Ustilago maydis	32.94	7.00e-30	124.00
IUUC-Vda-129680	Verticillium dahliae	32.47	1.00e-26	112.00
IUUC-Vvi-131292	Vitis vinifera	41.39	3.00e-63	234.00
IUUC-Xtr-132204	Xenopus tropicalis	44.44	3.00e-73	267.00
IUUC-Xma-133727	Xiphophorus maculatus	45.95	1.00e-72	265.00
IUUC-Zma-135908	Zea mays	41.70	1.00e-56	212.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence