iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mga-059995

Ensembl Protein ID

ENSMGAP00000014635.2

UniProt Accession

G1NM46; G1NM46_MELGA

Protein Name

Uncharacterized protein

Gene Name

PPARA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000013838.2	ENSMGAT00000015572.2	ENSMGAP00000014635.2
ENSMGAG00000013838.2	ENSMGAT00000018358.1	ENSMGAP00000017586.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	80.30	0.00e+00	754.00	IUUC-Hsa-046893

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

MVDTENHLYP LTPLEEDDIG SPLSGEFLQD MENIQDISQS LGDDSSGALS LTEFQSLGNG 60
PGSDGSVITD TLSPASSPSS INFATAPGSI DESPSGALNI ECRICGDKAS GYHYGVHACE 120

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Nucleotide Sequence
(Fasta)

ATGGTGGACA CTGAAAACCA TCTCTATCCA CTTACTCCCC TAGAGGAGGA TGATATAGGT 60
AGTCCTTTAT CTGGAGAGTT TCTACAAGAT ATGGAGAACA TACAAGACAT TTCTCAGTCT 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0675--Receptor
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003074--1Cnucl_rcpt
IPR003076--1Cnucl_rcpt_A
IPR000536--Nucl_hrmn_rcpt_lig-bd
IPR001723--Nuclear_hrmn_rcpt
IPR001628--Znf_hrmn_rcpt
IPR013088--Znf_NHR/GATA

PROSITE

PS00031--NUCLEAR_REC_DBD_1
PS51030--NUCLEAR_REC_DBD_2

Pfam

PF00104--Hormone_recep
PF00105--zf-C4

PRINTS

PR01288--PROXISOMEPAR
PR01289--PROXISOMPAAR
PR00398--STRDHORMONER
PR00047--STROIDFINGER

SMART

SM00430--HOLI
SM00399--ZnF_C4

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0008144--F:drug binding
GO:0008289--F:lipid binding
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0004879--F:RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
GO:0003707--F:steroid hormone receptor activity
GO:0001077--F:transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001190--F:transcriptional activator activity, RNA polymerase II transcription factor binding
GO:0001078--F:transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0008270--F:zinc ion binding
GO:0032922--P:circadian regulation of gene expression
GO:0008544--P:epidermis development
GO:0006631--P:fatty acid metabolic process
GO:0032099--P:negative regulation of appetite
GO:0010887--P:negative regulation of cholesterol storage
GO:0050728--P:negative regulation of inflammatory response
GO:1903038--P:negative regulation of leukocyte cell-cell adhesion
GO:0010745--P:negative regulation of macrophage derived foam cell differentiation
GO:1902894--P:negative regulation of pri-miRNA transcription from RNA polymerase II promoter
GO:0010871--P:negative regulation of receptor biosynthetic process
GO:0010891--P:negative regulation of sequestering of triglyceride
GO:0046321--P:positive regulation of fatty acid oxidation
GO:0045722--P:positive regulation of gluconeogenesis
GO:0072366--P:regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter
GO:0042752--P:regulation of circadian rhythm
GO:0072363--P:regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter
GO:0072369--P:regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter
GO:0042060--P:wound healing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002222	Ailuropoda melanoleuca	78.81	0.00e+00	764.00
IUUC-Apl-003330	Anas platyrhynchos	89.62	0.00e+00	838.00
IUUC-Aca-004598	Anolis carolinensis	80.51	0.00e+00	757.00
IUUC-Acl-008339	Aspergillus clavatus	45.45	1.30e-01	29.30
IUUC-Ame-011508	Astyanax mexicanus	65.40	4.00e-177	613.00
IUUC-Bta-012621	Bos taurus	79.45	0.00e+00	741.00
IUUC-Cja-019688	Callithrix jacchus	79.87	0.00e+00	745.00
IUUC-Cfa-020859	Canis familiaris	79.24	0.00e+00	764.00
IUUC-Cpo-021607	Cavia porcellus	73.94	0.00e+00	693.00
IUUC-Csa-023313	Chlorocebus sabaeus	80.30	0.00e+00	745.00
IUUC-Cho-024741	Choloepus hoffmanni	69.28	3.00e-176	610.00
IUUC-Cgl-026615	Colletotrichum gloeosporioides	30.51	1.20e+00	25.40
IUUC-Dre-027446	Danio rerio	65.12	7.00e-177	612.00
IUUC-Dno-029173	Dasypus novemcinctus	78.81	0.00e+00	731.00
IUUC-Dor-030581	Dipodomys ordii	75.58	0.00e+00	682.00
IUUC-Ete-032330	Echinops telfairi	76.27	0.00e+00	724.00
IUUC-Eca-033712	Equus caballus	79.03	0.00e+00	726.00
IUUC-Fca-036555	Felis catus	79.24	0.00e+00	765.00
IUUC-Fal-036677	Ficedula albicollis	87.71	0.00e+00	812.00
IUUC-Gmo-039240	Gadus morhua	73.02	2.00e-163	567.00
IUUC-Gga-040473	Gallus gallus	88.98	0.00e+00	827.00
IUUC-Gac-041872	Gasterosteus aculeatus	65.20	0.00e+00	628.00
IUUC-Ggo-045226	Gorilla gorilla	80.30	0.00e+00	746.00
IUUC-Hsa-046893	Homo sapiens	80.30	0.00e+00	746.00
IUUC-Itr-048952	Ictidomys tridecemlineatus	77.54	0.00e+00	724.00
IUUC-Lch-050116	Latimeria chalumnae	71.61	0.00e+00	676.00
IUUC-Loc-052131	Lepisosteus oculatus	74.75	2.00e-176	611.00
IUUC-Laf-054323	Loxodonta africana	79.03	0.00e+00	737.00
IUUC-Mcc-054841	Macaca mulatta	80.30	0.00e+00	741.00
IUUC-Meu-056833	Macropus eugenii	69.70	1.00e-179	622.00
IUUC-Mdo-061954	Monodelphis domestica	77.78	0.00e+00	657.00
IUUC-Mmu-064295	Mus musculus	75.85	0.00e+00	690.00
IUUC-Mpu-066216	Mustela putorius furo	79.24	0.00e+00	764.00
IUUC-Nle-069970	Nomascus leucogenys	80.08	0.00e+00	744.00
IUUC-Ont-071594	Oreochromis niloticus	66.04	2.00e-178	617.00
IUUC-Oan-073501	Ornithorhynchus anatinus	79.42	0.00e+00	657.00
IUUC-Ocu-074634	Oryctolagus cuniculus	71.20	0.00e+00	693.00
IUUC-Oni-082926	Oryza nivara	38.33	2.00e-04	36.60
IUUC-Ola-086585	Oryzias latipes	70.68	3.00e-160	557.00
IUUC-Oga-088738	Otolemur garnettii	80.30	0.00e+00	741.00
IUUC-Oar-090453	Ovis aries	79.03	0.00e+00	739.00
IUUC-Ptr-091518	Pan troglodytes	80.08	0.00e+00	739.00
IUUC-Pan-092006	Papio anubis	80.08	0.00e+00	740.00
IUUC-Psi-093352	Pelodiscus sinensis	83.05	0.00e+00	790.00
IUUC-Pfo-096060	Poecilia formosa	65.62	2.00e-178	618.00
IUUC-Pab-098602	Pongo abelii	74.06	0.00e+00	644.00
IUUC-Pva-102175	Pteropus vampyrus	78.18	0.00e+00	744.00
IUUC-Rno-105283	Rattus norvegicus	76.48	0.00e+00	691.00
IUUC-Sha-106560	Sarcophilus harrisii	79.24	0.00e+00	740.00
IUUC-Smo-109075	Selaginella moellendorffii	32.76	3.30e-02	31.20
IUUC-Ssc-115266	Sus scrofa	78.39	0.00e+00	765.00
IUUC-Tgu-116778	Taeniopygia guttata	87.50	0.00e+00	809.00
IUUC-Tru-118436	Takifugu rubripes	64.78	9.00e-180	622.00
IUUC-Tsy-119642	Tarsius syrichta	93.62	5.00e-129	453.00
IUUC-Tni-119859	Tetraodon nigroviridis	65.20	2.00e-179	621.00
IUUC-Tvi-122624	Trichoderma virens	27.27	1.20e+00	25.40
IUUC-Tbe-127464	Tupaia belangeri	79.03	0.00e+00	763.00
IUUC-Ttr-129307	Tursiops truncatus	75.90	0.00e+00	687.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence