iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Atr-003039

Ensembl Protein ID

ERM97215

UniProt Accession

W1NQ31; W1NQ31_AMBTC

Genbank Protein ID

ERM97215.1

Protein Name

Presenilin

Genbank Nucleotide ID

KI396540

Gene Name

AMTR_s00119p00061920

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AMTR_s00119p00061920	ERM97215	ERM97215

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/CUE	29.21	4.00e-40	162.00	IUUC-Cel-018553

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Amborella trichopoda

Functional Description
(View)

Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.

Protein Sequence
(Fasta)

MEKSILEAVG VEIIGVMAPV SACMFLVVLL VYNMSSQGSD STIRTAATLV YLEKSTDSNT 60
QKFEGALLNA GVFVILIALV TFLLVMLYYY RFTGFLKNYM RFSAFFVLGS MGGPIFLSII 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGAAAA GCATTTTGGA GGCTGTTGGT GTTGAAATCA TAGGGGTAAT GGCCCCTGTA 60
TCAGCCTGTA TGTTCCTTGT TGTTCTCTTG GTTTACAATA TGTCCTCTCA AGGATCAGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0256--Endoplasmic reticulum
KW-0333--Golgi apparatus
KW-0378--Hydrolase
KW-0472--Membrane
KW-0914--Notch signaling pathway
KW-0645--Protease
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001108--Peptidase_A22A
IPR006639--Preselin/SPP

Pfam

PF01080--Presenilin

PRINTS

PR01072--PRESENILIN

SMART

SM00730--PSN

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0005798--C:Golgi-associated vesicle
GO:0016021--C:integral component of membrane
GO:0004190--F:aspartic-type endopeptidase activity
GO:0007219--P:Notch signaling pathway
GO:0016485--P:protein processing

KEGG

atr:18425168

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000686	Aegilops tauschii	52.32	4.00e-88	318.00
IUUC-Aml-001648	Ailuropoda melanoleuca	36.72	1.00e-36	145.00
IUUC-Apl-003727	Anas platyrhynchos	33.04	1.00e-36	146.00
IUUC-Aca-004582	Anolis carolinensis	32.89	2.00e-36	145.00
IUUC-Aly-005455	Arabidopsis lyrata	57.26	2.00e-124	437.00
IUUC-Ath-006730	Arabidopsis thaliana	56.39	2.00e-126	444.00
IUUC-Ame-010686	Astyanax mexicanus	31.94	1.00e-26	112.00
IUUC-Bta-013026	Bos taurus	33.71	9.00e-38	150.00
IUUC-Bdi-014196	Brachypodium distachyon	52.32	7.00e-100	356.00
IUUC-Bol-015841	Brassica oleracea	59.83	9.00e-117	412.00
IUUC-Bra-017580	Brassica rapa	58.21	1.00e-103	368.00
IUUC-Cel-018553	Caenorhabditis elegans	29.57	2.00e-43	168.00
IUUC-Cja-019994	Callithrix jacchus	32.89	3.00e-36	144.00
IUUC-Cfa-020074	Canis familiaris	32.88	2.00e-37	149.00
IUUC-Cpo-022237	Cavia porcellus	33.11	7.00e-38	150.00
IUUC-Cre-022747	Chlamydomonas reinhardtii	45.54	3.00e-51	195.00
IUUC-Csa-023537	Chlorocebus sabaeus	33.26	1.00e-37	149.00
IUUC-Cho-024735	Choloepus hoffmanni	30.58	4.00e-33	134.00
IUUC-Cin-025780	Ciona intestinalis	31.81	8.00e-44	170.00
IUUC-Csv-025967	Ciona savignyi	30.30	2.00e-39	155.00
IUUC-Dre-028526	Danio rerio	29.31	6.00e-28	117.00
IUUC-Dno-029758	Dasypus novemcinctus	33.26	4.00e-37	147.00
IUUC-Dor-031127	Dipodomys ordii	31.86	3.00e-23	101.00
IUUC-Dme-031929	Drosophila melanogaster	31.14	8.00e-44	170.00
IUUC-Ete-032487	Echinops telfairi	34.23	8.00e-16	77.00
IUUC-Eca-034387	Equus caballus	31.86	8.00e-27	113.00
IUUC-Eeu-035134	Erinaceus europaeus	33.92	1.00e-33	135.00
IUUC-Fca-036243	Felis catus	33.78	1.00e-37	149.00
IUUC-Fal-036600	Ficedula albicollis	32.21	3.00e-37	148.00
IUUC-Gmo-038550	Gadus morhua	33.63	7.00e-26	110.00
IUUC-Gga-040993	Gallus gallus	32.43	2.00e-37	148.00
IUUC-Gac-042511	Gasterosteus aculeatus	31.71	3.00e-38	151.00
IUUC-Gma-043822	Glycine max	66.67	1.00e-52	199.00
IUUC-Ggo-044859	Gorilla gorilla	31.99	4.00e-26	110.00
IUUC-Hsa-046822	Homo sapiens	33.26	1.00e-37	149.00
IUUC-Hvu-047141	Hordeum vulgare	52.71	2.00e-94	338.00
IUUC-Itr-048420	Ictidomys tridecemlineatus	35.03	1.00e-35	142.00
IUUC-Lch-049946	Latimeria chalumnae	32.87	2.00e-23	102.00
IUUC-Lpe-051132	Leersia perrieri	52.94	9.00e-92	329.00
IUUC-Loc-052427	Lepisosteus oculatus	30.97	5.00e-40	157.00
IUUC-Laf-053758	Loxodonta africana	30.97	2.00e-36	145.00
IUUC-Mcc-055682	Macaca mulatta	33.26	1.00e-37	149.00
IUUC-Meu-056004	Macropus eugenii	32.87	1.00e-23	102.00
IUUC-Mtr-058392	Medicago truncatula	61.44	3.00e-116	410.00
IUUC-Mga-059466	Meleagris gallopavo	32.43	2.00e-37	149.00
IUUC-Mmr-060890	Microcebus murinus	31.42	1.00e-25	109.00
IUUC-Mdo-062122	Monodelphis domestica	32.58	1.00e-36	146.00
IUUC-Mmu-063176	Mus musculus	30.25	5.00e-31	127.00
IUUC-Mac-064858	Musa acuminata	85.87	3.00e-43	167.00
IUUC-Mpu-065927	Mustela putorius furo	32.66	3.00e-37	148.00
IUUC-Mlu-067079	Myotis lucifugus	32.81	2.00e-42	165.00
IUUC-Nle-070180	Nomascus leucogenys	33.26	1.00e-37	149.00
IUUC-Opr-070847	Ochotona princeps	34.58	2.00e-24	105.00
IUUC-Ont-071846	Oreochromis niloticus	30.61	3.00e-33	134.00
IUUC-Oan-072783	Ornithorhynchus anatinus	33.63	1.00e-33	135.00
IUUC-Ocu-074527	Oryctolagus cuniculus	33.41	2.00e-37	149.00
IUUC-Oba-075256	Oryza barthii	49.74	1.00e-84	305.00
IUUC-Obr-076302	Oryza brachyantha	67.61	2.00e-48	185.00
IUUC-Ogl-077097	Oryza glaberrima	49.38	5.00e-94	337.00
IUUC-Ogu-078570	Oryza glumaepatula	51.74	7.00e-92	329.00
IUUC-Oin-079244	Oryza indica	49.59	1.00e-94	338.00
IUUC-Olo-080484	Oryza longistaminata	48.60	1.00e-62	231.00
IUUC-Ome-081814	Oryza meridionalis	49.38	6.00e-95	339.00
IUUC-Oni-082057	Oryza nivara	51.97	2.00e-92	331.00
IUUC-Opu-084176	Oryza punctata	51.97	7.00e-91	326.00
IUUC-Oru-084618	Oryza rufipogon	51.97	5.00e-92	330.00
IUUC-Osa-085602	Oryza sativa	52.53	1.00e-93	335.00
IUUC-Ola-086707	Oryzias latipes	31.84	7.00e-27	112.00
IUUC-Olu-087811	Ostreococcus lucimarinus	40.55	3.00e-46	177.00
IUUC-Oga-088560	Otolemur garnettii	31.42	1.00e-25	109.00
IUUC-Oar-090348	Ovis aries	32.35	3.00e-39	154.00
IUUC-Ptr-091060	Pan troglodytes	33.26	1.00e-37	149.00
IUUC-Pan-091855	Papio anubis	34.72	3.00e-25	108.00
IUUC-Psi-093505	Pelodiscus sinensis	31.90	1.00e-37	149.00
IUUC-Pma-094612	Petromyzon marinus	31.94	9.00e-22	97.10
IUUC-Ppa-095431	Physcomitrella patens	45.04	5.00e-99	353.00
IUUC-Pfo-097396	Poecilia formosa	30.11	3.00e-38	151.00
IUUC-Pab-098591	Pongo abelii	33.26	1.00e-37	149.00
IUUC-Pop-099661	Populus trichocarpa	45.95	5.00e-88	317.00
IUUC-Pca-101029	Procavia capensis	35.74	3.00e-34	138.00
IUUC-Ppe-101495	Prunus persica	59.68	9.00e-143	498.00
IUUC-Pva-102244	Pteropus vampyrus	33.64	9.00e-26	110.00
IUUC-Rno-105861	Rattus norvegicus	34.26	9.00e-25	107.00
IUUC-Sha-107045	Sarcophilus harrisii	33.18	1.00e-37	149.00
IUUC-Smo-109325	Selaginella moellendorffii	51.57	3.00e-45	174.00
IUUC-Sit-110624	Setaria italica	51.15	5.00e-92	330.00
IUUC-Sly-110865	Solanum lycopersicum	84.51	4.00e-32	128.00
IUUC-Stu-112433	Solanum tuberosum	60.57	5.00e-122	429.00
IUUC-Sar-113169	Sorex araneus	43.93	6.00e-22	97.40
IUUC-Sbi-114305	Sorghum bicolor	50.42	8.00e-91	326.00
IUUC-Ssc-115766	Sus scrofa	32.96	3.00e-37	148.00
IUUC-Tgu-116469	Taeniopygia guttata	34.63	1.00e-34	139.00
IUUC-Tru-117732	Takifugu rubripes	29.66	3.00e-34	138.00
IUUC-Tsy-119624	Tarsius syrichta	31.67	4.00e-26	111.00
IUUC-Tni-119852	Tetraodon nigroviridis	29.60	6.00e-33	134.00
IUUC-Tca-121865	Theobroma cacao	60.75	1.00e-126	444.00
IUUC-Tae-123984	Triticum aestivum	52.60	6.00e-94	336.00
IUUC-Tur-126237	Triticum urartu	54.13	1.00e-86	312.00
IUUC-Tbe-128148	Tupaia belangeri	30.51	1.00e-25	109.00
IUUC-Ttr-128793	Tursiops truncatus	31.75	8.00e-34	137.00
IUUC-Vpa-130625	Vicugna pacos	43.81	2.00e-21	95.90
IUUC-Vvi-131312	Vitis vinifera	74.78	1.00e-77	282.00
IUUC-Xtr-131790	Xenopus tropicalis	33.80	8.00e-25	107.00
IUUC-Xma-133377	Xiphophorus maculatus	31.00	4.00e-38	151.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence