iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tru-118387

Ensembl Protein ID

ENSTRUP00000016967.1

UniProt Accession

H2SX29; H2SX29_TAKRU

Protein Name

Non-specific serine/threonine protein kinase

Gene Name

MARK3 (1 of many)

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000006908.1	ENSTRUT00000017034.1	ENSTRUP00000016961.1
ENSTRUG00000006908.1	ENSTRUT00000017035.1	ENSTRUP00000016962.1
ENSTRUG00000006908.1	ENSTRUT00000017036.1	ENSTRUP00000016963.1
ENSTRUG00000006908.1	ENSTRUT00000017037.1	ENSTRUP00000016964.1
ENSTRUG00000006908.1	ENSTRUT00000017038.1	ENSTRUP00000016965.1
ENSTRUG00000006908.1	ENSTRUT00000017039.1	ENSTRUP00000016966.1
ENSTRUG00000006908.1	ENSTRUT00000017040.1	ENSTRUP00000016967.1
ENSTRUG00000006908.1	ENSTRUT00000017041.1	ENSTRUP00000016968.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	78.94	0.00e+00	1189.00	IUUC-Hsa-046881

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MSTKTPLPTV NEKVTESHTT HTNGRQEIGT RSARTGVRSR SSEEPQQPHV GNYRLLKTIG 60
KGNFAKVKLA RHILTGREVA IKIIDKTQLN PNSLQKLFRE VRIMKILNHP NIVKLFEVIE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAACGGGAA AGATGTCAAC AAAAACTCCT TTACCGACGG TCAACGAAAA GGTGACGGAA 60
AGTGTAAGTA GAAAGGCTTG TTTTATAGCT AGCTGCACTT TGGATTGTGC TTTAAACAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR028375--KA1/Ssp2_C
IPR001772--KA1_dom
IPR011009--Kinase-like_dom
IPR033624--MARK/par1
IPR033628--MARK3
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS
IPR015940--UBA

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50030--UBA

Pfam

PF02149--KA1
PF00069--Pkinase

SMART

SM00220--S_TKc
SM00165--UBA

Gene Ontology

GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0030010--P:establishment of cell polarity
GO:0000226--P:microtubule cytoskeleton organization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001559	Ailuropoda melanoleuca	59.40	0.00e+00	837.00
IUUC-Aca-004735	Anolis carolinensis	72.62	0.00e+00	783.00
IUUC-Ame-011854	Astyanax mexicanus	56.02	0.00e+00	801.00
IUUC-Bta-013462	Bos taurus	60.50	0.00e+00	859.00
IUUC-Cel-018198	Caenorhabditis elegans	72.85	5.00e-161	561.00
IUUC-Cja-019358	Callithrix jacchus	58.56	0.00e+00	874.00
IUUC-Cfa-020081	Canis familiaris	79.64	0.00e+00	1093.00
IUUC-Cpo-022503	Cavia porcellus	78.20	0.00e+00	1137.00
IUUC-Csa-023035	Chlorocebus sabaeus	59.17	0.00e+00	890.00
IUUC-Cgl-026480	Colletotrichum gloeosporioides	40.85	2.00e-69	257.00
IUUC-Dre-028387	Danio rerio	79.07	0.00e+00	1146.00
IUUC-Dno-029052	Dasypus novemcinctus	78.44	0.00e+00	1142.00
IUUC-Dor-030743	Dipodomys ordii	59.24	0.00e+00	838.00
IUUC-Ete-032528	Echinops telfairi	59.10	0.00e+00	707.00
IUUC-Eca-033300	Equus caballus	79.03	0.00e+00	1130.00
IUUC-Eeu-034949	Erinaceus europaeus	70.94	0.00e+00	655.00
IUUC-Fca-036517	Felis catus	78.24	0.00e+00	1097.00
IUUC-Fal-037115	Ficedula albicollis	73.05	0.00e+00	962.00
IUUC-Gga-040502	Gallus gallus	72.38	0.00e+00	1096.00
IUUC-Gac-041559	Gasterosteus aculeatus	62.12	0.00e+00	844.00
IUUC-Hsa-046881	Homo sapiens	78.94	0.00e+00	1159.00
IUUC-Lch-049922	Latimeria chalumnae	79.89	0.00e+00	1142.00
IUUC-Loc-052896	Lepisosteus oculatus	82.08	0.00e+00	1176.00
IUUC-Laf-054590	Loxodonta africana	78.76	0.00e+00	1099.00
IUUC-Mcc-054721	Macaca mulatta	79.07	0.00e+00	1160.00
IUUC-Mmr-060647	Microcebus murinus	78.68	0.00e+00	1135.00
IUUC-Mdo-062445	Monodelphis domestica	69.17	0.00e+00	1065.00
IUUC-Mmu-064104	Mus musculus	68.90	0.00e+00	694.00
IUUC-Mpu-066504	Mustela putorius furo	78.59	0.00e+00	1100.00
IUUC-Mlu-067700	Myotis lucifugus	59.20	0.00e+00	820.00
IUUC-Nle-069385	Nomascus leucogenys	57.79	0.00e+00	860.00
IUUC-Opr-070418	Ochotona princeps	65.76	0.00e+00	884.00
IUUC-Ont-072503	Oreochromis niloticus	84.51	0.00e+00	1332.00
IUUC-Oan-072929	Ornithorhynchus anatinus	79.62	0.00e+00	1127.00
IUUC-Ocu-073853	Oryctolagus cuniculus	79.10	0.00e+00	1158.00
IUUC-Oar-090325	Ovis aries	78.96	0.00e+00	1138.00
IUUC-Ptr-091421	Pan troglodytes	58.92	0.00e+00	887.00
IUUC-Pan-092891	Papio anubis	71.22	0.00e+00	1079.00
IUUC-Psi-092994	Pelodiscus sinensis	79.74	0.00e+00	1149.00
IUUC-Pma-094666	Petromyzon marinus	62.47	0.00e+00	939.00
IUUC-Pab-098232	Pongo abelii	59.05	0.00e+00	889.00
IUUC-Pca-100880	Procavia capensis	73.47	0.00e+00	791.00
IUUC-Pgr-103687	Puccinia graminis	47.86	2.00e-69	257.00
IUUC-Rno-105027	Rattus norvegicus	68.90	0.00e+00	695.00
IUUC-Sha-107115	Sarcophilus harrisii	79.89	0.00e+00	1167.00
IUUC-Ssc-116439	Sus scrofa	74.19	0.00e+00	643.00
IUUC-Tgu-116652	Taeniopygia guttata	61.37	0.00e+00	901.00
IUUC-Tsy-119138	Tarsius syrichta	59.67	9.00e-173	600.00
IUUC-Tni-120412	Tetraodon nigroviridis	60.22	0.00e+00	867.00
IUUC-Tme-127019	Tuber melanosporum	40.91	4.00e-71	263.00
IUUC-Tbe-127841	Tupaia belangeri	70.21	7.00e-162	564.00
IUUC-Ttr-128406	Tursiops truncatus	60.80	0.00e+00	869.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence