iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-068190

Ensembl Protein ID

ENSMLUP00000002296.2

UniProt Accession

G1NY23; G1NY23_MYOLU

Genbank Protein ID

ENSMLUP00000002296

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02023782

Gene Name

ITSN2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000002494.2	ENSMLUT00000002526.2	ENSMLUP00000002296.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.40e-61	204.4	1130	1182

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           +v+++ydy a+n+deL++ kG  + v+  ++ d +W++g  e +g  GlfP+n+v+ 
   Q: 1130 QVIAMYDYAANNEDELNFSKGQLINVL--NKDDPDWWQG--EINGATGLFPSNYVKM 1182
           6899***********************..8889******..9*************85 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MMAQFPTAMN GGPNMWAITS EERTKHDKQF DNLKPAGGYI TGDQARTFFL QSGLPAPVLA 60
EIWALSDLNK DGKMDQQEFS IAMKLIKLKL QGQQLPVVLP PIMKQPPMFS PLISARFGMG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGATGGCTC AGTTTCCCAC AGCTATGAAT GGTAAGCGTA AGCAGCTTTG TGCTTGTAGG 60
AAGATAAAGA GGTTATGAGA TTGGGGGGAG CGGCGGGGAG TAGAGGTTAT AAAATATTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000008--C2_dom
IPR000219--DH-domain
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR000261--EH_dom
IPR027029--Intersectin-2
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50004--C2
PS50010--DH_2
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50031--EH
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF00168--C2
PF12763--EF-hand_4
PF16652--PH_13
PF00621--RhoGEF
PF00018--SH3_1
PF07653--SH3_2
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00239--C2
SM00054--EFh
SM00027--EH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005813--C:centrosome
GO:0070062--C:extracellular exosome
GO:0005509--F:calcium ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0006897--P:endocytosis
GO:1903861--P:positive regulation of dendrite extension
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001455	Ailuropoda melanoleuca	94.44	0.00e+00	2177.00
IUUC-Apl-004205	Anas platyrhynchos	79.06	0.00e+00	2463.00
IUUC-Aca-004287	Anolis carolinensis	83.94	0.00e+00	1669.00
IUUC-Acl-008295	Aspergillus clavatus	32.14	3.00e-15	77.40
IUUC-Ame-011759	Astyanax mexicanus	64.93	0.00e+00	1248.00
IUUC-Bta-013248	Bos taurus	88.97	0.00e+00	2063.00
IUUC-Cfa-020628	Canis familiaris	94.45	0.00e+00	2185.00
IUUC-Cpo-022427	Cavia porcellus	80.43	0.00e+00	2587.00
IUUC-Csa-023122	Chlorocebus sabaeus	90.86	0.00e+00	2140.00
IUUC-Cho-024969	Choloepus hoffmanni	59.00	0.00e+00	1141.00
IUUC-Cin-025435	Ciona intestinalis	44.94	0.00e+00	924.00
IUUC-Csv-026290	Ciona savignyi	54.20	0.00e+00	723.00
IUUC-Cne-026918	Cryptococcus neoformans	36.18	3.00e-39	158.00
IUUC-Cme-027247	Cyanidioschyzon merolae	27.17	5.00e-10	59.30
IUUC-Dre-028623	Danio rerio	68.42	0.00e+00	1222.00
IUUC-Dno-029419	Dasypus novemcinctus	92.65	0.00e+00	2159.00
IUUC-Dor-030504	Dipodomys ordii	76.73	0.00e+00	1721.00
IUUC-Dme-032099	Drosophila melanogaster	33.19	7.00e-58	219.00
IUUC-Ete-032927	Echinops telfairi	75.80	0.00e+00	820.00
IUUC-Eca-034196	Equus caballus	92.32	0.00e+00	2076.00
IUUC-Eeu-034972	Erinaceus europaeus	68.23	0.00e+00	635.00
IUUC-Fca-035757	Felis catus	93.95	0.00e+00	2187.00
IUUC-Fal-037531	Ficedula albicollis	87.73	0.00e+00	1756.00
IUUC-Gmo-039632	Gadus morhua	52.80	0.00e+00	1215.00
IUUC-Gga-041012	Gallus gallus	79.00	0.00e+00	1912.00
IUUC-Gac-041320	Gasterosteus aculeatus	54.12	0.00e+00	1261.00
IUUC-Ggo-045405	Gorilla gorilla	90.68	0.00e+00	2674.00
IUUC-Hsa-046833	Homo sapiens	94.05	0.00e+00	2127.00
IUUC-Itr-048773	Ictidomys tridecemlineatus	55.43	0.00e+00	1337.00
IUUC-Lch-050094	Latimeria chalumnae	74.11	0.00e+00	1674.00
IUUC-Loc-052646	Lepisosteus oculatus	71.44	0.00e+00	1448.00
IUUC-Mcc-054709	Macaca mulatta	93.56	0.00e+00	2149.00
IUUC-Meu-056396	Macropus eugenii	80.88	0.00e+00	1554.00
IUUC-Mla-059128	Melampsora laricipopulina	35.32	3.00e-40	161.00
IUUC-Mga-059997	Meleagris gallopavo	83.66	0.00e+00	2045.00
IUUC-Mvi-060268	Microbotryum violaceum	30.59	1.00e-46	182.00
IUUC-Mmr-060891	Microcebus murinus	91.42	0.00e+00	2182.00
IUUC-Mdo-062019	Monodelphis domestica	58.28	0.00e+00	1391.00
IUUC-Mmu-064226	Mus musculus	86.15	0.00e+00	2113.00
IUUC-Mpu-066431	Mustela putorius furo	91.34	0.00e+00	2160.00
IUUC-Nle-070116	Nomascus leucogenys	91.27	0.00e+00	1694.00
IUUC-Opr-070815	Ochotona princeps	78.61	0.00e+00	1760.00
IUUC-Ont-071752	Oreochromis niloticus	54.19	0.00e+00	1304.00
IUUC-Oan-073390	Ornithorhynchus anatinus	56.25	0.00e+00	1337.00
IUUC-Ocu-073753	Oryctolagus cuniculus	56.31	0.00e+00	1754.00
IUUC-Ola-086482	Oryzias latipes	60.79	0.00e+00	1234.00
IUUC-Oga-088449	Otolemur garnettii	90.60	0.00e+00	2084.00
IUUC-Oar-090275	Ovis aries	89.38	0.00e+00	2101.00
IUUC-Ptr-091667	Pan troglodytes	93.96	0.00e+00	2119.00
IUUC-Pan-091723	Papio anubis	87.60	0.00e+00	1821.00
IUUC-Psi-093136	Pelodiscus sinensis	82.15	0.00e+00	1952.00
IUUC-Pfo-096864	Poecilia formosa	53.28	0.00e+00	1580.00
IUUC-Pab-098755	Pongo abelii	91.44	0.00e+00	2046.00
IUUC-Pca-101134	Procavia capensis	86.57	0.00e+00	1510.00
IUUC-Pva-102433	Pteropus vampyrus	84.80	0.00e+00	1930.00
IUUC-Pgr-103473	Puccinia graminis	30.64	1.00e-38	156.00
IUUC-Ptt-103973	Puccinia triticina	25.26	5.00e-27	117.00
IUUC-Rno-105691	Rattus norvegicus	90.86	0.00e+00	2185.00
IUUC-Sce-106410	Saccharomyces cerevisiae	29.71	6.00e-12	65.90
IUUC-Sha-106851	Sarcophilus harrisii	57.57	0.00e+00	1409.00
IUUC-Sar-112978	Sorex araneus	91.02	0.00e+00	1434.00
IUUC-Sre-115028	Sporisorium reilianum	30.45	5.00e-35	144.00
IUUC-Ssc-115562	Sus scrofa	86.02	0.00e+00	1944.00
IUUC-Tgu-116758	Taeniopygia guttata	83.05	0.00e+00	2018.00
IUUC-Tru-117789	Takifugu rubripes	63.12	0.00e+00	1273.00
IUUC-Tsy-119039	Tarsius syrichta	69.79	0.00e+00	1063.00
IUUC-Tni-119958	Tetraodon nigroviridis	55.25	0.00e+00	1668.00
IUUC-Tbe-127477	Tupaia belangeri	91.75	0.00e+00	756.00
IUUC-Ttr-129196	Tursiops truncatus	91.10	0.00e+00	2053.00
IUUC-Uma-129456	Ustilago maydis	33.46	6.00e-33	137.00
IUUC-Vpa-130035	Vicugna pacos	81.22	0.00e+00	635.00
IUUC-Xtr-132905	Xenopus tropicalis	59.37	0.00e+00	1448.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence