iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066643

Ensembl Protein ID

ENSMPUP00000008450.1

UniProt Accession

M3YAU3; M3YAU3_MUSPF

Genbank Protein ID

ENSMPUP00000008450

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01055305

Gene Name

BRWD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000008515.1	ENSMPUT00000008586.1	ENSMPUP00000008450.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.80e-36	120.6	97	134
UBD/Beta-Prp	2.80e-55	187.6	199	456

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH + v+c+af  + +++ +GsdD+ +k+W+++ g+ll
   Q: 97   GHLSAVYCVAFdRTgHRIFTGSDDCLVKIWSTHNGRLL 134
           8**********955599***************999987 PP

UBD/Beta-Prp

   S: 22   ksllatgsrdgtikvwdvttgkl......lrslsgheaevtavk..fspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsvlsl 100
           +++++++++dgt+  w+++ ++l      l+  ++  ++v+ ++  fs  g +l+tgs+D++i+ +   +++++ +  l+ h+d+v s+
   Q: 199  QRYMVSTGADGTVCFWQWDLESLkfsprpLKFTEKPRPGVQMLCssFSVGGMFLATGSTDHVIRMYflGFEAPEKIAELESHTDKVDSI 287
           689*****************99999988777778888888755522888888**************99999****************** PP
   S: 101  sfspsgdklvsGshdrtirvwdletgqclee...............tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrt 174
           +f+ +gd+++sGs+d t+r+w  e+ ++ +                 ++  +  v++++++++++++v++ +D ++++W++ tg+ll+ 
   Q: 288  QFCNNGDRFLSGSRDGTARIWRFEQLEWRSIlldmatrvsgdlsleEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHN 376
           **************************99998999*********98877778889*********************************** PP
   S: 175  ltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsiriW 249
           l g h d v  l+   fds  + ++s+++dg++ +wd+ +g+ ++ + +         v + +fs+++++++++ s+g + i+
   Q: 377  LLG-HADEVFVLEthpFDS--RIMLSAGHDGSIFIWDITKGTKMKHYFNMIegqghGAVFDCKFSQDGQHFACTDSHGHLLIF 456
           **9.*********555555..99****************999977766544444456677789999*****999999998886 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MLDKEIPPSI SRVTSLLGAG RQSLLRTAKD CRHTVWKGSA FAALHRGRPP EMPVNYGSPP 60
SLVEIHRGKQ LTGCSTFSTA FPGTMYQHIK MHRRILGHLS AVYCVAFDRT GHRIFTGSDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCTTGTCCA ATAAGCATGT GGCTCCTGAT CATCTGTTGC AAATCTGCCA ACGCATTGGT 60
CCCATGTTGG ATAAAGAAAT TCCACCCAGT ATTTCAAGAG TCACTTCTTT ACTTGGTGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005730--C:nucleolus
GO:0007010--P:cytoskeleton organization
GO:0008360--P:regulation of cell shape
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002332	Ailuropoda melanoleuca	95.17	0.00e+00	3180.00
IUUC-Apl-004083	Anas platyrhynchos	63.54	0.00e+00	1976.00
IUUC-Bta-013217	Bos taurus	91.24	0.00e+00	3087.00
IUUC-Bol-015737	Brassica oleracea	31.55	1.00e-68	256.00
IUUC-Bra-017961	Brassica rapa	31.68	2.00e-68	254.00
IUUC-Cja-019966	Callithrix jacchus	89.17	0.00e+00	3067.00
IUUC-Cfa-021037	Canis familiaris	94.44	0.00e+00	3170.00
IUUC-Cpo-021934	Cavia porcellus	91.82	0.00e+00	2591.00
IUUC-Csa-023352	Chlorocebus sabaeus	89.41	0.00e+00	2919.00
IUUC-Cho-024690	Choloepus hoffmanni	78.31	0.00e+00	843.00
IUUC-Dno-028938	Dasypus novemcinctus	87.20	0.00e+00	2994.00
IUUC-Ete-032717	Echinops telfairi	79.29	0.00e+00	799.00
IUUC-Eca-034349	Equus caballus	91.12	0.00e+00	3008.00
IUUC-Fca-035485	Felis catus	92.22	0.00e+00	3073.00
IUUC-Gma-044324	Glycine max	31.08	1.00e-63	239.00
IUUC-Ggo-045500	Gorilla gorilla	89.64	0.00e+00	3016.00
IUUC-Hsa-046350	Homo sapiens	90.32	0.00e+00	3022.00
IUUC-Itr-047962	Ictidomys tridecemlineatus	95.93	0.00e+00	1125.00
IUUC-Lch-049662	Latimeria chalumnae	64.68	0.00e+00	1944.00
IUUC-Laf-053848	Loxodonta africana	88.30	0.00e+00	2975.00
IUUC-Mcc-054638	Macaca mulatta	89.58	0.00e+00	3016.00
IUUC-Meu-056739	Macropus eugenii	79.28	0.00e+00	1065.00
IUUC-Mga-060165	Meleagris gallopavo	77.16	0.00e+00	2143.00
IUUC-Mmr-061227	Microcebus murinus	89.17	0.00e+00	3025.00
IUUC-Mdo-062074	Monodelphis domestica	73.76	0.00e+00	2586.00
IUUC-Mmu-064075	Mus musculus	80.78	0.00e+00	2766.00
IUUC-Mlu-067735	Myotis lucifugus	88.49	0.00e+00	3007.00
IUUC-Nle-069402	Nomascus leucogenys	92.07	0.00e+00	2848.00
IUUC-Oan-072954	Ornithorhynchus anatinus	76.89	0.00e+00	2529.00
IUUC-Ocu-074456	Oryctolagus cuniculus	87.34	0.00e+00	3079.00
IUUC-Ogl-077493	Oryza glaberrima	27.29	1.00e-29	126.00
IUUC-Olu-087745	Ostreococcus lucimarinus	28.06	9.00e-56	212.00
IUUC-Oga-087938	Otolemur garnettii	81.82	0.00e+00	2713.00
IUUC-Oar-090214	Ovis aries	90.92	0.00e+00	3091.00
IUUC-Ptr-091213	Pan troglodytes	89.69	0.00e+00	2982.00
IUUC-Pan-092444	Papio anubis	89.06	0.00e+00	3006.00
IUUC-Pfo-097318	Poecilia formosa	61.85	0.00e+00	1655.00
IUUC-Pab-097573	Pongo abelii	88.89	0.00e+00	2928.00
IUUC-Pva-102782	Pteropus vampyrus	90.44	0.00e+00	3108.00
IUUC-Rno-105687	Rattus norvegicus	81.01	0.00e+00	2779.00
IUUC-Sha-106680	Sarcophilus harrisii	89.03	0.00e+00	1335.00
IUUC-Sar-113519	Sorex araneus	81.90	0.00e+00	1783.00
IUUC-Tsy-118921	Tarsius syrichta	89.10	0.00e+00	1885.00
IUUC-Tbe-127663	Tupaia belangeri	85.92	0.00e+00	1210.00
IUUC-Ttr-128561	Tursiops truncatus	88.12	0.00e+00	2857.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence