iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tae-125588

Ensembl Protein ID

TRIAE_CS42_4BL_TGACv1_320636_AA1045250.2

UniProt Accession

A0A1D5XHQ2; A0A1D5XHQ2_WHEAT

Protein Name

Eukaryotic translation initiation factor 3 subunit I

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TRIAE_CS42_4BL_TGACv1_320636_AA1045250	TRIAE_CS42_4BL_TGACv1_320636_AA1045250.1	TRIAE_CS42_4BL_TGACv1_320636_AA1045250.1
TRIAE_CS42_4BL_TGACv1_320636_AA1045250	TRIAE_CS42_4BL_TGACv1_320636_AA1045250.2	TRIAE_CS42_4BL_TGACv1_320636_AA1045250.2
TRIAE_CS42_4BL_TGACv1_320636_AA1045250	TRIAE_CS42_4BL_TGACv1_320636_AA1045250.4	TRIAE_CS42_4BL_TGACv1_320636_AA1045250.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-20	74.8	50	87

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrtgvll 36
           gH++ v++++   ++t+l++Gs D t k+WD++tg+ l
   Q: 50   GHNGAVWSCDVsrHSTRLITGSADQTAKLWDVKTGKEL 87
           8**********9644*******************9876 PP

Organism

Triticum aestivum

Functional Description
(View)

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Protein Sequence
(Fasta)

MRPILMKGHE RPLTFLKYNR DGDLLFSCAK DHTPTVWYAD NGDRLGTYRG HNGAVWSCDV 60
SRHSTRLITG SADQTAKLWD VKTGKELFTF RFDAPARSVD LAIGDHLAVI TTDSFMGNMP 120

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Nucleotide Sequence
(Fasta)

CTCACACAAA GCCTCTTGTC CAAGCGCAGC TAGGGTTTTG CTCCGCCGCA ACGCACGATC 60
TAGATCCCCA CACTTCCCTA ACCCTACCCA ACCCTACACC TCCCGGCGGC AGCGGCAGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0396--Initiation factor
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR027525--eIF3i
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016282--C:eukaryotic 43S preinitiation complex
GO:0033290--C:eukaryotic 48S preinitiation complex
GO:0005852--C:eukaryotic translation initiation factor 3 complex
GO:0003743--F:translation initiation factor activity
GO:0001731--P:formation of translation preinitiation complex
GO:0006446--P:regulation of translational initiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000115	Aegilops tauschii	69.90	3.00e-75	276.00
IUUC-Dor-030257	Dipodomys ordii	32.95	1.00e-25	110.00
IUUC-Ete-032336	Echinops telfairi	38.71	3.00e-42	165.00
IUUC-Lch-049620	Latimeria chalumnae	45.85	4.00e-78	285.00
IUUC-Ome-081228	Oryza meridionalis	69.58	1.00e-89	323.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence