iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053521

UUCD1 version

UUC-LoA-00231

Ensembl Protein ID

ENSLAFP00000005430.4

UniProt Accession

G3SY85; G3SY85_LOXAF

Protein Name

Uncharacterized protein

Gene Name

WDR47

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000006464.4	ENSLAFT00000006468.4	ENSLAFP00000005430.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.80e-29	100.9	753	789
UBD/Beta-Prp	3.30e-46	158.2	657	915

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtcla.fsdtllvsGsdDgtikvWDlrtgvll 36
           gHt+ + +l  +s+++++sGs D+t++ WDlr   ++
   Q: 753  GHTGHILALYtWSGWMIASGSQDKTVRFWDLRVPSCV 789
           89999***966977*****************988887 PP

UBD/Beta-Prp

   S: 6    kghhksvitcvkfspdksllatgsrdgtikvwdvttgkl.....lrslsgheaevtavkfspdgk....ilvtgse.Drtikvwdlstg 84
           ++hhk+ i+cv++sp ++llatgs d+ +kv  +  +++       ++s h+++++++ f +  +    il++++  D +i+  d + g
   Q: 657  NKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCnatgpDLEFSMHDGTIRDLAFMEGPEsggaILISAGAgDCNIYTTDCQRG 745
           68*****************************99999999889888899************987667778777765516788888***** PP
   S: 85   kcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee...tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgk 170
           + +h+l+gh+  +l+l     g  ++sGs+d+t+r wdl+  +c++    t+ g+ ++v +v+v+p+g+ll++G  D+ ++l+d++ g+
   Q: 746  QGLHALSGHTGHILALYTWS-GWMIASGSQDKTVRFWDLRVPSCVRVvgtTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGR 833
           **************997777.9***********************99999*************************************** PP
   S: 171  llrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlq....tgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW 249
           +++     h ++v+s+ f++   +l++gs+d ++k+ dlq    ++  ++ + +h+d v + r + +d  ++s s+D+++ +W
   Q: 834  MVQSYHP-HSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQgdltKQLPIMVVGEHKDKVIQCRWHTQDLSFLSSSADRTVTLW 915
           *****98.********************************99977788*********************************** PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MTAEETVNVK EVEIIKLILD FLNSKKLHIS MLALEKESGV INGLFSDDML FLRQLILDGQ 60
WDEVLQFIQP LECMEKFDKK RFRYIILKQK FLEALCVNNA MSAEDEPQHL EFTMQEAVQC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACGGCTG AAGAAACAGT GAATGTAAAA GAAGTTGAAA TCATTAAGTT AATTTTGGAC 60
TTCCTGAATT CAAAGAAGCT TCACATTAGT ATGTTGGCCC TCGAGAAGGA AAGTGGAGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR006595--CTLH_C
IPR006594--LisH
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50897--CTLH
PS50896--LISH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00668--CTLH
SM00667--LisH
SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001519	Ailuropoda melanoleuca	96.34	0.00e+00	1633.00
IUUC-Apl-003954	Anas platyrhynchos	91.22	0.00e+00	1551.00
IUUC-Aca-004766	Anolis carolinensis	88.38	0.00e+00	1476.00
IUUC-Ame-010725	Astyanax mexicanus	69.92	0.00e+00	1123.00
IUUC-Bta-013072	Bos taurus	95.12	0.00e+00	1596.00
IUUC-Cel-018667	Caenorhabditis elegans	48.33	4.00e-94	339.00
IUUC-Cja-018835	Callithrix jacchus	95.47	0.00e+00	1608.00
IUUC-Cfa-020380	Canis familiaris	94.38	0.00e+00	995.00
IUUC-Cpo-021883	Cavia porcellus	95.44	0.00e+00	1575.00
IUUC-Csa-023467	Chlorocebus sabaeus	96.63	0.00e+00	1625.00
IUUC-Cho-024342	Choloepus hoffmanni	86.75	0.00e+00	1465.00
IUUC-Cin-025112	Ciona intestinalis	44.20	3.00e-73	268.00
IUUC-Dre-027530	Danio rerio	76.57	0.00e+00	1252.00
IUUC-Dno-029290	Dasypus novemcinctus	96.85	0.00e+00	1628.00
IUUC-Dor-030258	Dipodomys ordii	81.76	0.00e+00	1335.00
IUUC-Dme-032040	Drosophila melanogaster	52.73	2.00e-103	368.00
IUUC-Ete-032248	Echinops telfairi	89.57	0.00e+00	782.00
IUUC-Eca-033623	Equus caballus	96.85	0.00e+00	1635.00
IUUC-Fca-036425	Felis catus	95.15	0.00e+00	1449.00
IUUC-Fal-036661	Ficedula albicollis	90.24	0.00e+00	1512.00
IUUC-Gmo-039527	Gadus morhua	73.72	0.00e+00	1226.00
IUUC-Gga-041177	Gallus gallus	90.55	0.00e+00	1522.00
IUUC-Gac-042049	Gasterosteus aculeatus	73.59	0.00e+00	1237.00
IUUC-Ggo-044833	Gorilla gorilla	95.69	0.00e+00	1621.00
IUUC-Hsa-046084	Homo sapiens	95.91	0.00e+00	1625.00
IUUC-Lch-050313	Latimeria chalumnae	79.98	0.00e+00	1389.00
IUUC-Loc-051790	Lepisosteus oculatus	81.58	0.00e+00	1397.00
IUUC-Mcc-055053	Macaca mulatta	96.63	0.00e+00	1624.00
IUUC-Meu-056734	Macropus eugenii	93.30	0.00e+00	687.00
IUUC-Mga-059381	Meleagris gallopavo	90.90	0.00e+00	1535.00
IUUC-Mmr-060859	Microcebus murinus	96.12	0.00e+00	1617.00
IUUC-Mdo-062501	Monodelphis domestica	91.65	0.00e+00	1447.00
IUUC-Mmu-063126	Mus musculus	94.57	0.00e+00	1576.00
IUUC-Mpu-066718	Mustela putorius furo	96.44	0.00e+00	1284.00
IUUC-Mlu-067246	Myotis lucifugus	95.66	0.00e+00	1607.00
IUUC-Nle-069807	Nomascus leucogenys	95.91	0.00e+00	1624.00
IUUC-Opr-070862	Ochotona princeps	83.92	1.00e-64	241.00
IUUC-Ont-072519	Oreochromis niloticus	75.91	0.00e+00	1244.00
IUUC-Oan-072740	Ornithorhynchus anatinus	88.49	0.00e+00	775.00
IUUC-Ocu-074898	Oryctolagus cuniculus	96.31	0.00e+00	1593.00
IUUC-Ola-086396	Oryzias latipes	75.78	0.00e+00	1281.00
IUUC-Oga-088563	Otolemur garnettii	95.47	0.00e+00	1607.00
IUUC-Oar-089926	Ovis aries	96.53	0.00e+00	1624.00
IUUC-Ptr-090706	Pan troglodytes	95.80	0.00e+00	1622.00
IUUC-Pan-091740	Papio anubis	96.74	0.00e+00	1626.00
IUUC-Psi-093938	Pelodiscus sinensis	90.18	0.00e+00	1535.00
IUUC-Pfo-096531	Poecilia formosa	76.48	0.00e+00	1254.00
IUUC-Pab-098312	Pongo abelii	96.20	0.00e+00	1622.00
IUUC-Pca-101100	Procavia capensis	92.31	0.00e+00	750.00
IUUC-Pva-102734	Pteropus vampyrus	85.82	0.00e+00	1182.00
IUUC-Rno-105625	Rattus norvegicus	94.25	0.00e+00	1537.00
IUUC-Sha-106999	Sarcophilus harrisii	90.14	0.00e+00	1495.00
IUUC-Sar-112988	Sorex araneus	83.90	0.00e+00	1167.00
IUUC-Ssc-115384	Sus scrofa	95.77	0.00e+00	1583.00
IUUC-Tgu-116808	Taeniopygia guttata	90.57	0.00e+00	1515.00
IUUC-Tru-118233	Takifugu rubripes	74.87	0.00e+00	1224.00
IUUC-Tsy-119509	Tarsius syrichta	98.94	0.00e+00	674.00
IUUC-Tni-120473	Tetraodon nigroviridis	73.82	0.00e+00	1249.00
IUUC-Tbe-127447	Tupaia belangeri	90.74	2.00e-144	506.00
IUUC-Ttr-128459	Tursiops truncatus	93.92	0.00e+00	1502.00
IUUC-Vpa-130258	Vicugna pacos	90.98	0.00e+00	997.00
IUUC-Xtr-132609	Xenopus tropicalis	78.91	0.00e+00	1318.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence