iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
RAID2
Protein-protein Interaction
IID	HINT
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	97.42	0.00e+00	1496.00	IUUC-Hsa-047030

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MAEAEEQETE SLEESTDESE EESEEEPKLK YERLSNGVTE ILQKDAASCM TVHDKFLALG 60
THYGKVYLLD VQGNITQKFD VSPVKINQIS LDESGEHMGV CSEDGKLQVF GLYSGEEFHE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTAAACCTAG GCTTCAAGTG TAAGTTTAGT GAGGTCCCTG AGTTACTATC CTTTCCCTGT 60
TAATAGAGAG AACAGTAGAG ATTGCAGAGA GGACTAAACG AGATAATTCA TACTTTTACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR000547--Clathrin_H-chain/VPS_repeat
IPR011990--TPR-like_helical_dom
IPR016902--VPS41
IPR015943--WD40/YVTN_repeat-like_dom
IPR017986--WD40_repeat_dom

PROSITE

PS50236--CHCR

Pfam

PF00637--Clathrin

SMART

SM00299--CLH

Gene Ontology

GO:0030123--C:AP-3 adaptor complex
GO:0071439--C:clathrin complex
GO:0030136--C:clathrin-coated vesicle
GO:0033263--C:CORVET complex
GO:0005769--C:early endosome
GO:0005798--C:Golgi-associated vesicle
GO:0030897--C:HOPS complex
GO:0005770--C:late endosome
GO:0031902--C:late endosome membrane
GO:0005765--C:lysosomal membrane
GO:0015630--C:microtubule cytoskeleton
GO:0051020--F:GTPase binding
GO:0043621--F:protein self-association
GO:0034058--P:endosomal vesicle fusion
GO:0008333--P:endosome to lysosome transport
GO:1902774--P:late endosome to lysosome transport
GO:0006623--P:protein targeting to vacuole
GO:0045055--P:regulated exocytosis
GO:0035542--P:regulation of SNARE complex assembly
GO:0042144--P:vacuole fusion, non-autophagic

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000207	Aegilops tauschii	35.12	4.00e-128	452.00
IUUC-Aml-001435	Ailuropoda melanoleuca	97.01	0.00e+00	1489.00
IUUC-Atr-002975	Amborella trichopoda	38.87	4.00e-156	545.00
IUUC-Apl-003254	Anas platyrhynchos	91.85	0.00e+00	1422.00
IUUC-Aca-005067	Anolis carolinensis	89.81	0.00e+00	1392.00
IUUC-Aly-005839	Arabidopsis lyrata	37.64	2.00e-152	533.00
IUUC-Ath-006625	Arabidopsis thaliana	37.53	1.00e-152	534.00
IUUC-Ago-007960	Ashbya gossypii	25.38	9.00e-69	255.00
IUUC-Acl-008174	Aspergillus clavatus	29.90	5.00e-52	200.00
IUUC-Afl-008524	Aspergillus flavus	44.74	1.00e-35	145.00
IUUC-Afu-009054	Aspergillus fumigatus	29.92	2.00e-55	211.00
IUUC-Ani-009250	Aspergillus nidulans	28.27	2.00e-45	178.00
IUUC-Ang-009665	Aspergillus niger	29.17	4.00e-55	210.00
IUUC-Aor-010230	Aspergillus oryzae	44.74	2.00e-35	145.00
IUUC-Ate-010464	Aspergillus terreus	44.74	6.00e-37	150.00
IUUC-Ame-011311	Astyanax mexicanus	75.61	0.00e+00	1112.00
IUUC-Bgr-012099	Blumeria graminis	27.08	2.00e-47	185.00
IUUC-Bta-013327	Bos taurus	96.88	0.00e+00	1487.00
IUUC-Bci-013660	Botrytis cinerea	27.43	3.00e-48	187.00
IUUC-Bdi-014641	Brachypodium distachyon	37.37	1.00e-141	497.00
IUUC-Bol-015685	Brassica oleracea	37.44	1.00e-152	533.00
IUUC-Bra-016918	Brassica rapa	36.99	9.00e-151	528.00
IUUC-Cel-018385	Caenorhabditis elegans	28.26	9.00e-86	311.00
IUUC-Cja-018994	Callithrix jacchus	97.01	0.00e+00	1485.00
IUUC-Cfa-020405	Canis familiaris	96.88	0.00e+00	1488.00
IUUC-Cpo-022163	Cavia porcellus	96.88	0.00e+00	1483.00
IUUC-Cre-022626	Chlamydomonas reinhardtii	28.11	1.00e-40	162.00
IUUC-Csa-023134	Chlorocebus sabaeus	97.55	0.00e+00	1494.00
IUUC-Cho-024913	Choloepus hoffmanni	84.16	0.00e+00	1196.00
IUUC-Cin-025239	Ciona intestinalis	45.14	0.00e+00	666.00
IUUC-Cgl-026706	Colletotrichum gloeosporioides	28.88	1.00e-49	192.00
IUUC-Cne-026799	Cryptococcus neoformans	37.29	9.00e-153	534.00
IUUC-Cme-027200	Cyanidioschyzon merolae	24.12	7.00e-10	59.70
IUUC-Dre-028115	Danio rerio	82.88	0.00e+00	1285.00
IUUC-Dor-030947	Dipodomys ordii	94.15	0.00e+00	1431.00
IUUC-Dse-031544	Dothistroma septosporum	28.60	9.00e-45	176.00
IUUC-Dme-031830	Drosophila melanogaster	39.57	4.00e-147	515.00
IUUC-Ete-033051	Echinops telfairi	94.61	6.00e-90	325.00
IUUC-Eca-033501	Equus caballus	97.55	0.00e+00	1497.00
IUUC-Eeu-034555	Erinaceus europaeus	90.89	0.00e+00	880.00
IUUC-Fca-035809	Felis catus	96.60	0.00e+00	1483.00
IUUC-Fal-037056	Ficedula albicollis	92.39	0.00e+00	1425.00
IUUC-Fox-037949	Fusarium oxysporum	27.52	1.00e-45	179.00
IUUC-Fso-038282	Fusarium solani	26.80	3.00e-42	167.00
IUUC-Gmo-038540	Gadus morhua	81.39	0.00e+00	1250.00
IUUC-Ggr-039733	Gaeumannomyces graminis	26.57	2.00e-53	204.00
IUUC-Gga-040446	Gallus gallus	92.12	0.00e+00	1422.00
IUUC-Gac-041462	Gasterosteus aculeatus	82.74	0.00e+00	1265.00
IUUC-Gma-043148	Glycine max	38.10	1.00e-157	550.00
IUUC-Hsa-047030	Homo sapiens	97.42	0.00e+00	1496.00
IUUC-Hvu-047693	Hordeum vulgare	37.02	3.00e-141	495.00
IUUC-Itr-048318	Ictidomys tridecemlineatus	97.83	0.00e+00	1500.00
IUUC-Kpa-049224	Komagataella pastoris	24.48	5.00e-56	213.00
IUUC-Lch-049444	Latimeria chalumnae	81.21	0.00e+00	1227.00
IUUC-Lpe-050942	Leersia perrieri	34.88	2.00e-121	430.00
IUUC-Loc-052260	Lepisosteus oculatus	81.28	0.00e+00	1272.00
IUUC-Lma-053173	Leptosphaeria maculans	27.62	1.00e-47	185.00
IUUC-Laf-054185	Loxodonta africana	97.55	0.00e+00	1493.00
IUUC-Mcc-054816	Macaca mulatta	97.42	0.00e+00	1494.00
IUUC-Meu-056483	Macropus eugenii	72.71	0.00e+00	653.00
IUUC-Mor-056979	Magnaporthe oryzae	27.48	1.00e-50	195.00
IUUC-Mpo-057312	Magnaporthe poae	26.52	3.00e-53	204.00
IUUC-Mtr-057630	Medicago truncatula	37.66	3.00e-156	545.00
IUUC-Mla-058930	Melampsora laricipopulina	30.94	1.00e-24	106.00
IUUC-Mga-059942	Meleagris gallopavo	91.98	0.00e+00	1416.00
IUUC-Mvi-060386	Microbotryum violaceum	37.28	2.00e-151	530.00
IUUC-Mmr-060640	Microcebus murinus	97.96	0.00e+00	1503.00
IUUC-Mdo-062934	Monodelphis domestica	84.23	0.00e+00	1248.00
IUUC-Mmu-063488	Mus musculus	99.05	0.00e+00	1513.00
IUUC-Mac-064975	Musa acuminata	38.69	6.00e-152	531.00
IUUC-Mpu-065777	Mustela putorius furo	97.42	0.00e+00	1499.00
IUUC-Mlu-068052	Myotis lucifugus	96.21	0.00e+00	1480.00
IUUC-Nfi-068436	Neosartorya fischeri	29.66	8.00e-56	213.00
IUUC-Ncr-068840	Neurospora crassa	28.91	1.00e-55	212.00
IUUC-Nle-070063	Nomascus leucogenys	97.01	0.00e+00	1486.00
IUUC-Opr-070385	Ochotona princeps	85.87	0.00e+00	1269.00
IUUC-Ont-072367	Oreochromis niloticus	82.09	0.00e+00	1256.00
IUUC-Oan-073085	Ornithorhynchus anatinus	91.17	0.00e+00	1403.00
IUUC-Ocu-074672	Oryctolagus cuniculus	97.28	0.00e+00	1491.00
IUUC-Oba-075574	Oryza barthii	37.55	9.00e-146	511.00
IUUC-Obr-076203	Oryza brachyantha	37.90	8.00e-146	511.00
IUUC-Ogl-077909	Oryza glaberrima	37.55	9.00e-146	511.00
IUUC-Ogu-078053	Oryza glumaepatula	37.42	8.00e-145	508.00
IUUC-Oin-079700	Oryza indica	37.55	1.00e-145	510.00
IUUC-Olo-080707	Oryza longistaminata	37.47	5.00e-152	531.00
IUUC-Oni-082754	Oryza nivara	37.47	1.00e-144	507.00
IUUC-Opu-083854	Oryza punctata	37.47	6.00e-145	508.00
IUUC-Oru-085071	Oryza rufipogon	37.55	7.00e-146	511.00
IUUC-Osa-085370	Oryza sativa	37.55	9.00e-146	511.00
IUUC-Ola-086362	Oryzias latipes	80.82	0.00e+00	1231.00
IUUC-Oga-088078	Otolemur garnettii	97.40	0.00e+00	1483.00
IUUC-Oar-089679	Ovis aries	97.01	0.00e+00	1489.00
IUUC-Ptr-091680	Pan troglodytes	97.42	0.00e+00	1496.00
IUUC-Pan-092816	Papio anubis	98.01	0.00e+00	1016.00
IUUC-Psi-093890	Pelodiscus sinensis	92.12	0.00e+00	1427.00
IUUC-Pma-094654	Petromyzon marinus	67.03	0.00e+00	1027.00
IUUC-Pno-095071	Phaeosphaeria nodorum	28.27	1.00e-54	208.00
IUUC-Ppa-095198	Physcomitrella patens	36.09	3.00e-141	496.00
IUUC-Pfo-097465	Poecilia formosa	80.30	0.00e+00	1235.00
IUUC-Pab-098686	Pongo abelii	97.28	0.00e+00	1494.00
IUUC-Pop-100066	Populus trichocarpa	37.60	3.00e-154	539.00
IUUC-Pca-100990	Procavia capensis	87.64	0.00e+00	1309.00
IUUC-Ppe-101500	Prunus persica	38.11	2.00e-157	549.00
IUUC-Pva-102809	Pteropus vampyrus	96.60	0.00e+00	1485.00
IUUC-Pgr-103404	Puccinia graminis	34.02	7.00e-137	481.00
IUUC-Ptt-103952	Puccinia triticina	32.46	1.00e-125	444.00
IUUC-Pte-104216	Pyrenophora teres	28.22	3.00e-54	207.00
IUUC-Sce-106462	Saccharomyces cerevisiae	24.97	3.00e-57	217.00
IUUC-Sha-106689	Sarcophilus harrisii	93.34	0.00e+00	1444.00
IUUC-Sja-107696	Schizosaccharomyces japonicus	30.56	3.00e-93	336.00
IUUC-Spo-108173	Schizosaccharomyces pombe	30.08	3.00e-104	373.00
IUUC-Smo-109505	Selaginella moellendorffii	38.45	3.00e-143	502.00
IUUC-Sit-110176	Setaria italica	37.40	6.00e-152	531.00
IUUC-Sly-111671	Solanum lycopersicum	37.26	6.00e-157	548.00
IUUC-Sar-113073	Sorex araneus	82.20	0.00e+00	1215.00
IUUC-Sbi-114139	Sorghum bicolor	38.13	6.00e-145	508.00
IUUC-Sre-115158	Sporisorium reilianum	36.80	1.00e-160	561.00
IUUC-Ssc-115894	Sus scrofa	94.97	0.00e+00	1457.00
IUUC-Tgu-117481	Taeniopygia guttata	92.12	0.00e+00	1425.00
IUUC-Tru-118468	Takifugu rubripes	80.98	0.00e+00	1257.00
IUUC-Tni-120478	Tetraodon nigroviridis	80.71	0.00e+00	1253.00
IUUC-Tca-121780	Theobroma cacao	37.92	1.00e-154	540.00
IUUC-Tre-121900	Trichoderma reesei	28.05	6.00e-52	199.00
IUUC-Tvi-122343	Trichoderma virens	28.63	1.00e-52	202.00
IUUC-Tae-123578	Triticum aestivum	37.48	2.00e-143	503.00
IUUC-Tur-126430	Triticum urartu	36.66	3.00e-135	476.00
IUUC-Tme-127007	Tuber melanosporum	30.63	2.00e-56	214.00
IUUC-Tbe-128073	Tupaia belangeri	87.91	0.00e+00	1317.00
IUUC-Ttr-128879	Tursiops truncatus	96.74	0.00e+00	1475.00
IUUC-Uma-129356	Ustilago maydis	35.96	1.00e-157	550.00
IUUC-Vda-129676	Verticillium dahliae	28.85	4.00e-52	200.00
IUUC-Vvi-131744	Vitis vinifera	37.74	4.00e-154	538.00
IUUC-Xtr-132093	Xenopus tropicalis	81.45	0.00e+00	1271.00
IUUC-Xma-133199	Xiphophorus maculatus	81.25	0.00e+00	1234.00
IUUC-Yli-134385	Yarrowia lipolytica	27.05	4.00e-73	270.00
IUUC-Zma-135567	Zea mays	37.71	4.00e-142	499.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence