iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093298

Ensembl Protein ID

ENSPSIP00000011487.1

UniProt Accession

K7FTX7; K7FTX7_PELSI

Genbank Protein ID

ENSPSIP00000011487

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01003014

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000010279.1	ENSPSIT00000011544.1	ENSPSIP00000011487.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	6.00e-131	436.8	401	733

Active Site

Position(s)	Description	Evidence
702	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR001569-1, ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           ++dl krl+++f+gEegld+gGv+re+l+lls+e+ np++glf+ys +d +tlq+npds + npehl++F+f+Gr++g+a+++g+++d 
   Q: 401  PKDLWKRLMIKFRGEEGLDYGGVAREWLYLLSHEMLNPYYGLFQYSRDDIYTLQINPDSAV-NPEHLSYFHFVGRIMGMAVFHGHYIDG 488
           678999*****************************************************98.89************************* PP
   S: 91   plsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvve 179
            ++ +fyk+llgk+++l+d+e vdp+l++sl +i+en   di+   ld tf+v+++ +ge+ ++eLkp+G++ipVt+eNk+eYv+l+v+
   Q: 489  GFTLPFYKQLLGKPITLDDMELVDPDLHNSLVWILEN---DITGV-LDHTFCVEHNAYGEIIQHELKPNGKSIPVTEENKKEYVRLYVN 573
           ***********************************99...9***8.******************************************* PP
   S: 180  yrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFv 268
           +r+ +gi+ q+ a+++Gfnevip++ll+ F+e+elel+icG  +idv+d+k++t+ k+ +t+ds+ ++wFw+++e f++e r+++LqFv
   Q: 574  WRFLRGIEAQFLALQKGFNEVIPQHLLKTFDEKELELIICGLGKIDVNDWKANTRLKH-CTPDSNIVKWFWKAVEFFDEERRARLLQFV 661
           ********************************************************99.****************************** PP
   S: 269  TgssrlPlgGfaelk....prlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           Tgssr+Pl+Gf++l+    prlf+i++ das+++lP+++TCfn++++P+Y+++++l+ekLl+Aieet gF +
   Q: 662  TGSSRVPLQGFKALQgaagPRLFTIHQiDASTNNLPKAHTCFNRIDIPPYETYDKLYEKLLTAIEETCGFAV 733
           **********************************************************************76 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

AVLCAKNLVK KDFFRLPDPF AKVVVDGSGQ CHSTDTVKNT LDPKWNQHYD LYIGKSDSIT 60
ISVWNHKKIH KKQGAGFLGC VRLLSNAINR LKDTGYQRLD LCKLGPNDND TVRGQIVVSL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCAGTACTAT GTGCAAAAAA CTTGGTGAAA AAGGATTTTT TCCGTAAGTA GCTATTAAAA 60
TTTATGAATT CATGTGTGGT ACATGTTACA TACATTCTGT ACATCACTTC TAACATAGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000008--C2_dom
IPR000569--HECT_dom
IPR001202--WW_dom

PROSITE

PS50004--C2
PS50237--HECT
PS01159--WW_DOMAIN_1
PS50020--WW_DOMAIN_2

Pfam

PF00168--C2
PF00632--HECT
PF00397--WW

SMART

SM00239--C2
SM00119--HECTc
SM00456--WW

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001305	Ailuropoda melanoleuca	97.96	0.00e+00	1479.00
IUUC-Apl-003513	Anas platyrhynchos	98.64	0.00e+00	1497.00
IUUC-Aca-005358	Anolis carolinensis	97.97	0.00e+00	1486.00
IUUC-Ame-011320	Astyanax mexicanus	88.53	0.00e+00	1375.00
IUUC-Bta-013399	Bos taurus	97.82	0.00e+00	1472.00
IUUC-Cja-019355	Callithrix jacchus	97.82	0.00e+00	1475.00
IUUC-Cfa-020568	Canis familiaris	70.72	0.00e+00	1110.00
IUUC-Cpo-022200	Cavia porcellus	98.09	0.00e+00	1481.00
IUUC-Csa-024145	Chlorocebus sabaeus	74.56	0.00e+00	1141.00
IUUC-Cho-024804	Choloepus hoffmanni	98.06	0.00e+00	639.00
IUUC-Cin-025126	Ciona intestinalis	66.36	0.00e+00	967.00
IUUC-Csv-026339	Ciona savignyi	64.67	0.00e+00	996.00
IUUC-Dre-027650	Danio rerio	90.79	0.00e+00	1416.00
IUUC-Dno-029534	Dasypus novemcinctus	97.68	0.00e+00	1476.00
IUUC-Ete-032715	Echinops telfairi	93.03	0.00e+00	1387.00
IUUC-Eca-033580	Equus caballus	97.96	0.00e+00	1477.00
IUUC-Eeu-034945	Erinaceus europaeus	96.14	0.00e+00	1373.00
IUUC-Fca-035905	Felis catus	72.74	0.00e+00	1123.00
IUUC-Fal-037275	Ficedula albicollis	98.10	0.00e+00	1483.00
IUUC-Gga-041060	Gallus gallus	95.39	0.00e+00	1423.00
IUUC-Gac-041295	Gasterosteus aculeatus	92.83	0.00e+00	1413.00
IUUC-Ggo-045408	Gorilla gorilla	67.10	0.00e+00	1023.00
IUUC-Hsa-046726	Homo sapiens	97.96	0.00e+00	1477.00
IUUC-Itr-048317	Ictidomys tridecemlineatus	70.94	0.00e+00	1118.00
IUUC-Lch-050026	Latimeria chalumnae	96.07	0.00e+00	1445.00
IUUC-Loc-051760	Lepisosteus oculatus	88.74	0.00e+00	1394.00
IUUC-Laf-053753	Loxodonta africana	97.82	0.00e+00	1477.00
IUUC-Mcc-054815	Macaca mulatta	97.68	0.00e+00	1473.00
IUUC-Meu-056436	Macropus eugenii	74.80	0.00e+00	1066.00
IUUC-Mga-059723	Meleagris gallopavo	76.92	0.00e+00	1154.00
IUUC-Mmr-060806	Microcebus murinus	98.09	0.00e+00	1479.00
IUUC-Mdo-062805	Monodelphis domestica	96.73	0.00e+00	1454.00
IUUC-Mmu-064034	Mus musculus	97.68	0.00e+00	1472.00
IUUC-Mpu-066762	Mustela putorius furo	97.96	0.00e+00	1478.00
IUUC-Mlu-066981	Myotis lucifugus	97.82	0.00e+00	1477.00
IUUC-Nle-069804	Nomascus leucogenys	97.96	0.00e+00	1475.00
IUUC-Opr-070591	Ochotona princeps	92.49	0.00e+00	1377.00
IUUC-Ont-071239	Oreochromis niloticus	93.64	0.00e+00	1423.00
IUUC-Oan-072699	Ornithorhynchus anatinus	95.24	0.00e+00	1463.00
IUUC-Ocu-074913	Oryctolagus cuniculus	97.96	0.00e+00	1478.00
IUUC-Ola-086597	Oryzias latipes	86.67	0.00e+00	1305.00
IUUC-Olu-087813	Ostreococcus lucimarinus	42.22	2.00e-85	308.00
IUUC-Oga-089116	Otolemur garnettii	94.41	0.00e+00	1416.00
IUUC-Oar-089366	Ovis aries	97.82	0.00e+00	1473.00
IUUC-Ptr-091382	Pan troglodytes	97.96	0.00e+00	1477.00
IUUC-Pan-092479	Papio anubis	71.87	0.00e+00	1121.00
IUUC-Pma-094354	Petromyzon marinus	73.61	0.00e+00	1113.00
IUUC-Pfo-096071	Poecilia formosa	91.26	0.00e+00	1411.00
IUUC-Pab-098682	Pongo abelii	97.96	0.00e+00	1476.00
IUUC-Pop-099520	Populus trichocarpa	46.15	4.00e-92	334.00
IUUC-Pca-100516	Procavia capensis	88.66	0.00e+00	629.00
IUUC-Pva-102754	Pteropus vampyrus	96.86	0.00e+00	1443.00
IUUC-Rno-105600	Rattus norvegicus	97.96	0.00e+00	1278.00
IUUC-Sha-107144	Sarcophilus harrisii	96.78	0.00e+00	1352.00
IUUC-Spo-108171	Schizosaccharomyces pombe	40.30	9.00e-163	566.00
IUUC-Sar-113122	Sorex araneus	86.75	0.00e+00	1263.00
IUUC-Ssc-116413	Sus scrofa	73.10	0.00e+00	1101.00
IUUC-Tgu-117112	Taeniopygia guttata	97.56	0.00e+00	1478.00
IUUC-Tru-118497	Takifugu rubripes	90.09	0.00e+00	1354.00
IUUC-Tsy-119455	Tarsius syrichta	69.97	0.00e+00	1042.00
IUUC-Tni-120781	Tetraodon nigroviridis	90.23	0.00e+00	1181.00
IUUC-Tme-126897	Tuber melanosporum	39.12	1.00e-151	530.00
IUUC-Tbe-127371	Tupaia belangeri	88.31	0.00e+00	1186.00
IUUC-Ttr-129305	Tursiops truncatus	90.13	0.00e+00	1268.00
IUUC-Vpa-130591	Vicugna pacos	87.57	0.00e+00	1282.00
IUUC-Xtr-132979	Xenopus tropicalis	78.83	0.00e+00	1111.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence