iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pfo-097145

Ensembl Protein ID

ENSPFOP00000002781.2

UniProt Accession

A0A087XAH8; A0A087XAH8_POEFO

Genbank Protein ID

ENSPFOP00000002781

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AYCK01016314

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPFOG00000002640.2	ENSPFOT00000002785.2	ENSPFOP00000002781.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	5.10e-134	447.5	584	914

Active Site

Position(s)	Description	Evidence
884	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR001569-1, ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlp 91
           + lk+rl+vef+gE+gld+gG++re+++l+ske++np++glf+ys++d++tlq+np+sgl+n++hl +F+f+Gr+ g+a+++g+lld++
   Q: 584  DLLKARLWVEFKGEKGLDYGGLAREWFFLMSKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLTYFKFIGRVAGMAVFHGKLLDAF 672
           66899************************************************************************************ PP
   S: 92   lsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvvey 180
           + ++fyk++l+k+++l+d+e+vd+e+++slk+i+en   d e+  ldl+f+++ee++get++++LkpgG++i VtneNk++Y++lv+++
   Q: 673  FIRPFYKMMLQKPITLQDMESVDSEYFNSLKWILEN---DPED--LDLRFTIDEELFGETHQHDLKPGGSEIVVTNENKKQYIDLVMQW 756
           **********************************99...6666..79999999************************************ PP
   S: 181  rlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvT 269
           r+ ++i++q+ af+eGf e+ip++l+++F+e+elell+cG  ++dv+d++++tkyk+gy  d+ +iqwFw+++  +++e+r ++LqFvT
   Q: 757  RFVNRIQKQMMAFKEGFFELIPKDLIRIFDENELELLMCGLGDVDVNDWRQNTKYKNGYCGDHMVIQWFWKTVLLMDAEKRIRLLQFVT 845
           ***************************************************************************************** PP
   S: 270  gssrlPlgGfaelk....prlfvirkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFe 334
           g+sr+P++Gfael     p+lf+i+ +++ d+lP+++TCfn+L+LP+Y+s e+l+ekL +Aie+++gF+
   Q: 846  GTSRVPMNGFAELYgsngPQLFTIELWGTSDKLPRAHTCFNRLDLPPYESFEKLREKLNIAIENAQGFD 914
           ********************************************************************8 PP

Organism

Poecilia formosa

Protein Sequence
(Fasta)

MMAAVSASQI RGLQADEETS RILKVKVIAG IGLAKKDILG ASDPYTRLSL YDPVNGEITS 60
LQTKTIKKTL DPKWNEEFYF RVNPRSHRLL FEVFDENRLT RDDFLGQVDV PLNQIPTENP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATACTCGGTT GTAGCAGGAA CCCTGAACAA AAAAAAAAAG GAGGAGGAAG CAGGAGGTGG 60
AGGAAGAGGA TGGGTATTAT TACCAATGAC GATAAGGCCA CAACTATCCA CTCGGTCTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000008--C2_dom
IPR000569--HECT_dom
IPR001202--WW_dom

PROSITE

PS50004--C2
PS50237--HECT
PS01159--WW_DOMAIN_1
PS50020--WW_DOMAIN_2

Pfam

PF00168--C2
PF00632--HECT
PF00397--WW

SMART

SM00239--C2
SM00119--HECTc
SM00456--WW

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Acl-008273	Aspergillus clavatus	49.33	4.00e-159	555.00
IUUC-Afl-008713	Aspergillus flavus	48.65	1.00e-156	547.00
IUUC-Afu-009103	Aspergillus fumigatus	48.82	4.00e-159	555.00
IUUC-Ani-009259	Aspergillus nidulans	48.91	9.00e-158	551.00
IUUC-Ang-009738	Aspergillus niger	48.33	1.00e-156	547.00
IUUC-Ate-010529	Aspergillus terreus	48.57	1.00e-158	553.00
IUUC-Ame-011138	Astyanax mexicanus	87.50	0.00e+00	874.00
IUUC-Bta-012453	Bos taurus	66.95	0.00e+00	1076.00
IUUC-Bci-013785	Botrytis cinerea	47.20	1.00e-152	533.00
IUUC-Cel-018564	Caenorhabditis elegans	39.58	5.00e-175	608.00
IUUC-Cja-019034	Callithrix jacchus	67.11	0.00e+00	1013.00
IUUC-Cfa-020258	Canis familiaris	68.33	0.00e+00	1087.00
IUUC-Cpo-021648	Cavia porcellus	67.67	0.00e+00	1233.00
IUUC-Csa-023334	Chlorocebus sabaeus	68.81	0.00e+00	1248.00
IUUC-Cin-025157	Ciona intestinalis	63.27	0.00e+00	777.00
IUUC-Cgl-026642	Colletotrichum gloeosporioides	48.13	2.00e-152	533.00
IUUC-Dre-027924	Danio rerio	70.60	0.00e+00	1074.00
IUUC-Dno-029466	Dasypus novemcinctus	62.13	0.00e+00	1159.00
IUUC-Dse-031241	Dothistroma septosporum	47.81	2.00e-154	539.00
IUUC-Ete-032409	Echinops telfairi	62.57	0.00e+00	876.00
IUUC-Eca-033441	Equus caballus	68.61	0.00e+00	1190.00
IUUC-Fca-036384	Felis catus	68.77	0.00e+00	1110.00
IUUC-Fal-037547	Ficedula albicollis	69.21	0.00e+00	1236.00
IUUC-Fox-037774	Fusarium oxysporum	48.63	5.00e-155	541.00
IUUC-Fso-038393	Fusarium solani	47.97	1.00e-152	533.00
IUUC-Gmo-039679	Gadus morhua	72.07	0.00e+00	1318.00
IUUC-Gga-040524	Gallus gallus	69.34	0.00e+00	1243.00
IUUC-Gac-042607	Gasterosteus aculeatus	75.43	0.00e+00	1377.00
IUUC-Hsa-045968	Homo sapiens	62.17	0.00e+00	1159.00
IUUC-Itr-048383	Ictidomys tridecemlineatus	61.03	0.00e+00	888.00
IUUC-Lch-050445	Latimeria chalumnae	69.20	0.00e+00	1137.00
IUUC-Loc-052645	Lepisosteus oculatus	74.16	0.00e+00	1350.00
IUUC-Mcc-055821	Macaca mulatta	62.81	0.00e+00	1151.00
IUUC-Meu-056897	Macropus eugenii	86.41	7.00e-156	545.00
IUUC-Mor-057097	Magnaporthe oryzae	44.56	2.00e-153	536.00
IUUC-Mga-059362	Meleagris gallopavo	66.95	0.00e+00	1229.00
IUUC-Mmr-061061	Microcebus murinus	68.64	0.00e+00	1121.00
IUUC-Mmu-064136	Mus musculus	61.22	0.00e+00	1146.00
IUUC-Mpu-066567	Mustela putorius furo	69.48	0.00e+00	1262.00
IUUC-Mlu-068148	Myotis lucifugus	68.45	0.00e+00	1101.00
IUUC-Nfi-068427	Neosartorya fischeri	48.82	2.00e-159	556.00
IUUC-Ncr-068918	Neurospora crassa	47.48	1.00e-153	537.00
IUUC-Nle-069225	Nomascus leucogenys	68.21	0.00e+00	1125.00
IUUC-Ont-071664	Oreochromis niloticus	77.46	0.00e+00	1394.00
IUUC-Oan-073019	Ornithorhynchus anatinus	69.84	0.00e+00	1187.00
IUUC-Ola-087467	Oryzias latipes	61.69	0.00e+00	1112.00
IUUC-Oga-088241	Otolemur garnettii	62.64	0.00e+00	962.00
IUUC-Oar-089797	Ovis aries	68.74	0.00e+00	1171.00
IUUC-Ptr-090939	Pan troglodytes	62.17	0.00e+00	1159.00
IUUC-Pan-092284	Papio anubis	62.17	0.00e+00	1161.00
IUUC-Psi-093618	Pelodiscus sinensis	68.94	0.00e+00	1103.00
IUUC-Pno-095118	Phaeosphaeria nodorum	48.29	1.00e-157	550.00
IUUC-Pab-098394	Pongo abelii	68.66	0.00e+00	1235.00
IUUC-Pca-100568	Procavia capensis	62.52	0.00e+00	905.00
IUUC-Pte-104016	Pyrenophora teres	48.81	2.00e-157	549.00
IUUC-Pyt-104550	Pyrenophora triticirepentis	48.81	2.00e-157	549.00
IUUC-Rno-105318	Rattus norvegicus	60.91	0.00e+00	1118.00
IUUC-Sha-107370	Sarcophilus harrisii	65.13	0.00e+00	1086.00
IUUC-Sja-107786	Schizosaccharomyces japonicus	48.87	8.00e-152	531.00
IUUC-Ssl-108514	Sclerotinia sclerotiorum	47.45	2.00e-153	536.00
IUUC-Tgu-117474	Taeniopygia guttata	68.54	0.00e+00	1250.00
IUUC-Tru-117675	Takifugu rubripes	72.89	0.00e+00	1337.00
IUUC-Tni-119993	Tetraodon nigroviridis	71.72	0.00e+00	1301.00
IUUC-Tvi-122595	Trichoderma virens	45.20	6.00e-153	535.00
IUUC-Tbe-127408	Tupaia belangeri	63.23	0.00e+00	842.00
IUUC-Vpa-130503	Vicugna pacos	66.18	0.00e+00	971.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence