iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-048715

Ensembl Protein ID

ENSSTOP00000003423.2

UniProt Accession

I3M322; I3M322_ICTTR

Genbank Protein ID

ENSSTOP00000003423

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01029977

Gene Name

Sik1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000003810.2	ENSSTOT00000003819.2	ENSSTOP00000003423.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	81.93	0.00e+00	1106.00	IUUC-Hsa-046775

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MVIMSEFSAA PAGADQGQQK PLRVGFYDVE RTLGKGNFAV VKLARHRVTK TQVAIKIIDK 60
TRLDSSNLEK IYREVQLMKL LNHPHIIKLY QVMETKDMLY IVTEFAKNGE MFDYLTSNGH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGGCTGGGG CGTGCGCAGC CTCGGCCGGC GTCCGCGCTG AGCTCGCCCC TCGCTGGTCT 60
GCAGGTGCGG CCCGGAGCCA TGGTGATCAT GTCCGAGTTC AGTGCGGCCC CGGCGGGCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS
IPR034672--SIK
IPR015940--UBA

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50030--UBA

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0043276--P:anoikis
GO:0055007--P:cardiac muscle cell differentiation
GO:0043153--P:entrainment of circadian clock by photoperiod
GO:0035556--P:intracellular signal transduction
GO:0032792--P:negative regulation of CREB transcription factor activity
GO:0045721--P:negative regulation of gluconeogenesis
GO:0010868--P:negative regulation of triglyceride biosynthetic process
GO:0007346--P:regulation of mitotic cell cycle
GO:0010830--P:regulation of myotube differentiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-004739	Anolis carolinensis	68.32	0.00e+00	940.00
IUUC-Ame-011603	Astyanax mexicanus	64.47	0.00e+00	740.00
IUUC-Cja-019873	Callithrix jacchus	80.13	0.00e+00	1068.00
IUUC-Cfa-020801	Canis familiaris	80.18	0.00e+00	996.00
IUUC-Cpo-022296	Cavia porcellus	81.62	0.00e+00	1065.00
IUUC-Csa-023676	Chlorocebus sabaeus	80.84	0.00e+00	1084.00
IUUC-Cho-025021	Choloepus hoffmanni	74.81	3.00e-149	522.00
IUUC-Cin-025762	Ciona intestinalis	63.31	4.00e-126	445.00
IUUC-Csv-026013	Ciona savignyi	57.52	2.00e-120	425.00
IUUC-Dre-028021	Danio rerio	60.18	0.00e+00	743.00
IUUC-Dno-029103	Dasypus novemcinctus	75.08	0.00e+00	775.00
IUUC-Dme-031957	Drosophila melanogaster	63.83	2.00e-128	453.00
IUUC-Ete-033190	Echinops telfairi	83.33	0.00e+00	694.00
IUUC-Eca-033614	Equus caballus	58.82	3.00e-112	399.00
IUUC-Gmo-039423	Gadus morhua	60.03	0.00e+00	730.00
IUUC-Gga-040174	Gallus gallus	67.70	0.00e+00	894.00
IUUC-Gac-041875	Gasterosteus aculeatus	73.67	6.00e-156	544.00
IUUC-Ggo-045090	Gorilla gorilla	80.89	0.00e+00	1084.00
IUUC-Hsa-046775	Homo sapiens	81.55	0.00e+00	1081.00
IUUC-Lch-049933	Latimeria chalumnae	58.69	0.00e+00	780.00
IUUC-Loc-052048	Lepisosteus oculatus	59.63	0.00e+00	798.00
IUUC-Laf-054466	Loxodonta africana	77.25	0.00e+00	1040.00
IUUC-Mcc-054655	Macaca mulatta	81.09	0.00e+00	1087.00
IUUC-Meu-056705	Macropus eugenii	75.00	0.00e+00	800.00
IUUC-Mmr-061419	Microcebus murinus	82.42	0.00e+00	1087.00
IUUC-Mdo-062854	Monodelphis domestica	70.32	0.00e+00	895.00
IUUC-Mmu-064252	Mus musculus	85.53	0.00e+00	1242.00
IUUC-Nle-069329	Nomascus leucogenys	77.79	0.00e+00	1027.00
IUUC-Opr-071101	Ochotona princeps	65.56	0.00e+00	680.00
IUUC-Ont-071887	Oreochromis niloticus	60.25	0.00e+00	701.00
IUUC-Oan-073050	Ornithorhynchus anatinus	75.08	0.00e+00	891.00
IUUC-Oga-088220	Otolemur garnettii	82.19	0.00e+00	1089.00
IUUC-Oar-089420	Ovis aries	73.69	0.00e+00	920.00
IUUC-Ptr-091258	Pan troglodytes	81.55	0.00e+00	1081.00
IUUC-Pan-092031	Papio anubis	81.09	0.00e+00	1089.00
IUUC-Pfo-097451	Poecilia formosa	62.11	0.00e+00	701.00
IUUC-Pab-097806	Pongo abelii	81.68	0.00e+00	1083.00
IUUC-Pva-102182	Pteropus vampyrus	70.00	0.00e+00	768.00
IUUC-Sha-107262	Sarcophilus harrisii	68.90	0.00e+00	962.00
IUUC-Ssc-115584	Sus scrofa	93.95	5.00e-142	496.00
IUUC-Tgu-116973	Taeniopygia guttata	75.00	0.00e+00	876.00
IUUC-Tru-117598	Takifugu rubripes	60.65	7.00e-118	418.00
IUUC-Tsy-118859	Tarsius syrichta	54.33	2.00e-86	313.00
IUUC-Tni-120589	Tetraodon nigroviridis	60.06	7.00e-119	421.00
IUUC-Tbe-127501	Tupaia belangeri	59.64	2.00e-125	443.00
IUUC-Ttr-128365	Tursiops truncatus	78.13	0.00e+00	874.00
IUUC-Xtr-131848	Xenopus tropicalis	57.70	2.00e-113	404.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence