iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oga-088953

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03089053

Gene Name

MDM4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000011679.2	ENSOGAT00000011682.2	ENSOGAP00000010451.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	89.09	0.00e+00	814.00	IUUC-Hsa-046950

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MTSLSTSAQC STSDGACRIS SGQTNKVRPK LPLLKILQAA GAQGEMFTVK EVMHYLGQYI 60
MVKQLYDQQE QHMVYCGGDL LGELLGCQSF SVKDPSPLYD MLRKNLVTLA TPTTDAAQTL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACATCAT TGTCTACTTC TGCCCAGTGT TCAACATCTG ACGGTGCTTG TAGGATCTCT 60
TCAGGACAAA CCAATAAGGT AAATAATTTT GGGGTATTCC TTCTTTCAAT TAAAAAAAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR015458--MDM4
IPR016495--p53_neg-reg_MDM_2/4
IPR003121--SWIB_MDM2_domain
IPR001876--Znf_RanBP2
IPR001841--Znf_RING

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2
PS50089--ZF_RING_2

Pfam

PF02201--SWIB
PF00641--zf-RanBP

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0008283--P:cell proliferation
GO:0071456--P:cellular response to hypoxia
GO:0030330--P:DNA damage response, signal transduction by p53 class mediator
GO:0045023--P:G0 to G1 transition
GO:0043066--P:negative regulation of apoptotic process
GO:0071157--P:negative regulation of cell cycle arrest
GO:0042177--P:negative regulation of protein catabolic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0006461--P:protein complex assembly
GO:0050821--P:protein stabilization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001467	Ailuropoda melanoleuca	86.90	0.00e+00	760.00
IUUC-Apl-003800	Anas platyrhynchos	59.27	5.00e-152	530.00
IUUC-Aca-004608	Anolis carolinensis	56.36	5.00e-138	484.00
IUUC-Ame-010869	Astyanax mexicanus	46.45	4.00e-104	371.00
IUUC-Bta-013287	Bos taurus	83.84	0.00e+00	811.00
IUUC-Cja-019305	Callithrix jacchus	87.68	0.00e+00	791.00
IUUC-Cfa-020393	Canis familiaris	87.70	0.00e+00	782.00
IUUC-Cpo-022166	Cavia porcellus	84.68	0.00e+00	721.00
IUUC-Csa-023654	Chlorocebus sabaeus	88.69	0.00e+00	771.00
IUUC-Cho-024403	Choloepus hoffmanni	86.89	3.00e-127	447.00
IUUC-Cin-025448	Ciona intestinalis	28.97	4.00e-21	94.70
IUUC-Dre-027754	Danio rerio	47.66	2.00e-118	419.00
IUUC-Dno-029630	Dasypus novemcinctus	85.08	0.00e+00	814.00
IUUC-Dor-031064	Dipodomys ordii	65.86	0.00e+00	636.00
IUUC-Ete-032901	Echinops telfairi	75.81	0.00e+00	732.00
IUUC-Eca-034234	Equus caballus	88.69	0.00e+00	879.00
IUUC-Eeu-035015	Erinaceus europaeus	63.51	2.00e-157	549.00
IUUC-Fca-036587	Felis catus	88.69	0.00e+00	813.00
IUUC-Fal-036906	Ficedula albicollis	51.00	9.00e-130	456.00
IUUC-Gmo-038646	Gadus morhua	44.29	5.00e-96	344.00
IUUC-Gga-040124	Gallus gallus	55.69	1.00e-109	389.00
IUUC-Gac-042397	Gasterosteus aculeatus	45.97	2.00e-106	379.00
IUUC-Ggo-045505	Gorilla gorilla	89.09	0.00e+00	794.00
IUUC-Hsa-046950	Homo sapiens	89.09	0.00e+00	796.00
IUUC-Itr-048886	Ictidomys tridecemlineatus	85.66	0.00e+00	785.00
IUUC-Lch-050141	Latimeria chalumnae	52.57	5.00e-121	427.00
IUUC-Loc-051921	Lepisosteus oculatus	48.81	3.00e-112	399.00
IUUC-Laf-054281	Loxodonta africana	83.03	0.00e+00	747.00
IUUC-Mcc-055462	Macaca mulatta	85.48	0.00e+00	723.00
IUUC-Meu-056294	Macropus eugenii	71.77	9.00e-143	499.00
IUUC-Mga-059924	Meleagris gallopavo	58.67	3.00e-162	564.00
IUUC-Mmr-061428	Microcebus murinus	90.51	0.00e+00	860.00
IUUC-Mdo-062643	Monodelphis domestica	74.65	0.00e+00	702.00
IUUC-Mmu-063229	Mus musculus	81.21	0.00e+00	769.00
IUUC-Mpu-065782	Mustela putorius furo	86.52	0.00e+00	775.00
IUUC-Mlu-068105	Myotis lucifugus	77.22	0.00e+00	734.00
IUUC-Nle-069549	Nomascus leucogenys	89.49	0.00e+00	799.00
IUUC-Opr-070568	Ochotona princeps	85.93	0.00e+00	747.00
IUUC-Ont-072276	Oreochromis niloticus	46.72	3.00e-114	405.00
IUUC-Oan-072787	Ornithorhynchus anatinus	71.06	0.00e+00	648.00
IUUC-Ocu-074912	Oryctolagus cuniculus	86.06	0.00e+00	791.00
IUUC-Ola-087037	Oryzias latipes	43.76	2.00e-96	346.00
IUUC-Oar-089202	Ovis aries	84.24	0.00e+00	818.00
IUUC-Ptr-090964	Pan troglodytes	89.09	0.00e+00	796.00
IUUC-Pan-091975	Papio anubis	88.89	0.00e+00	789.00
IUUC-Psi-093558	Pelodiscus sinensis	59.19	6.00e-158	550.00
IUUC-Pfo-096454	Poecilia formosa	45.95	3.00e-111	395.00
IUUC-Pab-098123	Pongo abelii	89.09	0.00e+00	796.00
IUUC-Pca-101112	Procavia capensis	74.60	0.00e+00	689.00
IUUC-Pva-103098	Pteropus vampyrus	78.18	0.00e+00	745.00
IUUC-Rno-105930	Rattus norvegicus	82.06	0.00e+00	749.00
IUUC-Sha-107512	Sarcophilus harrisii	72.78	7.00e-180	623.00
IUUC-Sar-113584	Sorex araneus	78.12	0.00e+00	683.00
IUUC-Tgu-116766	Taeniopygia guttata	54.23	5.00e-98	350.00
IUUC-Tru-117829	Takifugu rubripes	46.63	1.00e-111	397.00
IUUC-Tsy-119268	Tarsius syrichta	74.55	0.00e+00	654.00
IUUC-Tni-120204	Tetraodon nigroviridis	45.80	2.00e-107	382.00
IUUC-Tbe-127840	Tupaia belangeri	79.87	3.00e-119	421.00
IUUC-Ttr-128863	Tursiops truncatus	85.05	0.00e+00	790.00
IUUC-Vpa-130718	Vicugna pacos	88.06	0.00e+00	769.00
IUUC-Xtr-132320	Xenopus tropicalis	46.65	1.00e-90	326.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence