iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000026833.6	ENSRNOT00000021321.5	ENSRNOP00000021321.4
ENSRNOG00000026833.6	ENSRNOT00000085022.1	ENSRNOP00000070856.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	TRANSFAC	RAID2
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	3.40e-22	78.7	1007	1078

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlp.sGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceens 73
            ++efl+pI+ +lM+dPvvlp s++t+drs+I+++l s+++ +P++r+plt +++ Pn++l++ iq+w++e++
   Q: 1007 ACDEFLDPIMSTLMSDPVVLPsSRVTVDRSTIARHLLSDQT-DPFNRSPLTMDQIRPNTELKEKIQRWLAERK 1078
           579******************9******************9.***************************9976 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MTDQENNNNI SSNPFAALFG SLADAKQFAA IHKEQLKQQS GSVFGSEEGA LCNSLHVPAD 60
ELPASPDDSD NSVSESLDEF DYSVSEISRS FRTHQEMCEQ LNINHMIQRI FLITLDNSDP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCTCAGCGA TGATGTCAGC TCCGGTTGCC TTGTTGAGTC GGAAGTGAGA ACCTTTTGGT 60
CGCTGTAGCT CTGAGGTGTC GTTCCTGCCC TTTCAGGCTC TGGTAAGAGG GAGGGTATCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR019474--Ub_conjug_fac_E4_core
IPR003613--Ubox_domain
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51698--U_BOX

Pfam

PF04564--U-box
PF10408--Ufd2P_core

SMART

SM00504--Ubox

Gene Ontology

GO:0005737--C:cytoplasm
GO:0000151--C:ubiquitin ligase complex
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0000209--P:protein polyubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001281	Ailuropoda melanoleuca	94.51	0.00e+00	2041.00
IUUC-Apl-003514	Anas platyrhynchos	88.24	0.00e+00	1875.00
IUUC-Aca-005167	Anolis carolinensis	83.19	0.00e+00	1737.00
IUUC-Ame-010905	Astyanax mexicanus	65.34	0.00e+00	698.00
IUUC-Bta-012413	Bos taurus	93.37	0.00e+00	2042.00
IUUC-Cja-019715	Callithrix jacchus	94.78	0.00e+00	2071.00
IUUC-Cfa-021185	Canis familiaris	95.12	0.00e+00	2105.00
IUUC-Cpo-021516	Cavia porcellus	95.40	0.00e+00	2077.00
IUUC-Csa-023765	Chlorocebus sabaeus	95.48	0.00e+00	2054.00
IUUC-Cho-024614	Choloepus hoffmanni	97.50	0.00e+00	860.00
IUUC-Cin-025532	Ciona intestinalis	37.12	4.00e-164	572.00
IUUC-Csv-025834	Ciona savignyi	52.90	1.00e-48	184.00
IUUC-Dre-028223	Danio rerio	75.21	0.00e+00	1590.00
IUUC-Dno-029785	Dasypus novemcinctus	93.92	0.00e+00	2051.00
IUUC-Dor-030421	Dipodomys ordii	91.49	0.00e+00	1948.00
IUUC-Dme-031715	Drosophila melanogaster	35.69	4.00e-136	479.00
IUUC-Ete-032767	Echinops telfairi	93.55	0.00e+00	1299.00
IUUC-Eca-033587	Equus caballus	95.03	0.00e+00	2070.00
IUUC-Fca-035622	Felis catus	94.33	0.00e+00	2094.00
IUUC-Fal-037262	Ficedula albicollis	85.57	0.00e+00	1873.00
IUUC-Gmo-038686	Gadus morhua	71.07	0.00e+00	1551.00
IUUC-Gga-041222	Gallus gallus	85.66	0.00e+00	1915.00
IUUC-Gac-042637	Gasterosteus aculeatus	71.90	0.00e+00	1545.00
IUUC-Ggo-044685	Gorilla gorilla	94.87	0.00e+00	2075.00
IUUC-Hsa-046176	Homo sapiens	95.39	0.00e+00	2080.00
IUUC-Itr-048469	Ictidomys tridecemlineatus	97.96	0.00e+00	1060.00
IUUC-Lch-049630	Latimeria chalumnae	79.08	0.00e+00	1728.00
IUUC-Loc-052727	Lepisosteus oculatus	74.93	0.00e+00	1627.00
IUUC-Laf-054041	Loxodonta africana	94.38	0.00e+00	2085.00
IUUC-Mcc-055099	Macaca mulatta	96.04	0.00e+00	2099.00
IUUC-Meu-055991	Macropus eugenii	86.20	0.00e+00	1902.00
IUUC-Mga-059596	Meleagris gallopavo	87.46	0.00e+00	1764.00
IUUC-Mmr-061244	Microcebus murinus	92.86	0.00e+00	1698.00
IUUC-Mdo-062335	Monodelphis domestica	87.03	0.00e+00	1894.00
IUUC-Mmu-063572	Mus musculus	99.08	0.00e+00	2162.00
IUUC-Mpu-066444	Mustela putorius furo	90.82	0.00e+00	1991.00
IUUC-Mlu-068232	Myotis lucifugus	93.36	0.00e+00	2048.00
IUUC-Nle-070036	Nomascus leucogenys	94.78	0.00e+00	2070.00
IUUC-Opr-070503	Ochotona princeps	88.12	0.00e+00	1330.00
IUUC-Ont-072389	Oreochromis niloticus	74.22	0.00e+00	1590.00
IUUC-Oan-073114	Ornithorhynchus anatinus	87.26	0.00e+00	1705.00
IUUC-Ocu-074370	Oryctolagus cuniculus	96.21	0.00e+00	1813.00
IUUC-Ola-086562	Oryzias latipes	72.68	0.00e+00	1571.00
IUUC-Oga-088146	Otolemur garnettii	93.90	0.00e+00	2040.00
IUUC-Oar-089190	Ovis aries	93.36	0.00e+00	2016.00
IUUC-Ptr-090592	Pan troglodytes	94.60	0.00e+00	2071.00
IUUC-Pan-092271	Papio anubis	95.48	0.00e+00	2082.00
IUUC-Psi-093730	Pelodiscus sinensis	85.86	0.00e+00	1906.00
IUUC-Pma-094120	Petromyzon marinus	76.39	1.00e-131	462.00
IUUC-Pfo-097077	Poecilia formosa	72.33	0.00e+00	1552.00
IUUC-Pab-098069	Pongo abelii	94.51	0.00e+00	2035.00
IUUC-Pca-100762	Procavia capensis	89.84	0.00e+00	1914.00
IUUC-Pva-103149	Pteropus vampyrus	93.86	0.00e+00	2056.00
IUUC-Sha-106555	Sarcophilus harrisii	87.40	0.00e+00	1934.00
IUUC-Sly-110848	Solanum lycopersicum	39.47	3.00e-77	282.00
IUUC-Sar-113131	Sorex araneus	89.72	0.00e+00	1175.00
IUUC-Ssc-115841	Sus scrofa	94.01	0.00e+00	2051.00
IUUC-Tgu-116823	Taeniopygia guttata	84.71	0.00e+00	1847.00
IUUC-Tru-118249	Takifugu rubripes	72.08	0.00e+00	1550.00
IUUC-Tsy-119112	Tarsius syrichta	97.35	0.00e+00	738.00
IUUC-Tni-119848	Tetraodon nigroviridis	71.34	0.00e+00	1519.00
IUUC-Tbe-127889	Tupaia belangeri	79.20	0.00e+00	840.00
IUUC-Ttr-129300	Tursiops truncatus	83.60	0.00e+00	1132.00
IUUC-Vpa-130215	Vicugna pacos	93.32	0.00e+00	2029.00
IUUC-Xtr-132107	Xenopus tropicalis	77.74	0.00e+00	1669.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence