iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074843

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02000892

Gene Name

WDR77

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000007801.2	ENSOCUT00000007800.2	ENSOCUP00000006741.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.80e-17	62.8	166	201

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf...sdtllvsGsdDgtikvWDlrtgv 34
           H++ vtc+a     d  ++s+s D+ i +WD+r+ +
   Q: 166  HAGQVTCVAAsphKDSVFLSCSEDNRILLWDTRCPK 201
           99******9886644789*************99876 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MRKETPPPPV PPAAREWNLP PNAPACMERQ LEAARYRSDG ALLLGASSLS GRCWAGSLWL 60
FKDPRAAPNE GFCSAGVQTE AGVADLTWVG DRGILVASDS GAVELWELDE NETLIVSKFC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCGGAAGG AAACTCCGCC TCCTCCAGTG CCCCCGGCGG CCCGCGAGTG GAACCTTCCC 60
CCTAATGCGC CCGCCTGCAT GGAACGGCAG TTGGAGGCTG CGCGGTACCG GTCTGGTGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0034709--C:methylosome
GO:0005654--C:nucleoplasm
GO:0030374--F:ligand-dependent nuclear receptor transcription coactivator activity
GO:0008327--F:methyl-CpG binding
GO:0060770--P:negative regulation of epithelial cell proliferation involved in prostate gland development
GO:0008284--P:positive regulation of cell proliferation
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0060528--P:secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002192	Ailuropoda melanoleuca	92.71	5.00e-177	613.00
IUUC-Apl-003921	Anas platyrhynchos	62.30	2.00e-65	241.00
IUUC-Aca-004870	Anolis carolinensis	70.00	2.00e-119	421.00
IUUC-Ame-011872	Astyanax mexicanus	46.96	4.00e-36	144.00
IUUC-Bta-013325	Bos taurus	94.17	8.00e-179	619.00
IUUC-Cja-019059	Callithrix jacchus	94.17	7.00e-178	615.00
IUUC-Cfa-021036	Canis familiaris	92.47	2.00e-157	548.00
IUUC-Cpo-022369	Cavia porcellus	92.13	4.00e-174	603.00
IUUC-Csa-023585	Chlorocebus sabaeus	94.17	2.00e-178	618.00
IUUC-Cho-024470	Choloepus hoffmanni	83.88	4.00e-115	406.00
IUUC-Dno-029867	Dasypus novemcinctus	89.50	1.00e-171	595.00
IUUC-Dor-030834	Dipodomys ordii	65.99	5.00e-111	394.00
IUUC-Ete-032245	Echinops telfairi	84.25	1.00e-140	491.00
IUUC-Eca-033360	Equus caballus	92.13	8.00e-172	595.00
IUUC-Eeu-035353	Erinaceus europaeus	88.92	7.00e-170	589.00
IUUC-Fca-036277	Felis catus	94.17	6.00e-179	619.00
IUUC-Fal-037383	Ficedula albicollis	67.83	9.00e-103	365.00
IUUC-Gmo-038575	Gadus morhua	54.40	5.00e-96	343.00
IUUC-Gga-040658	Gallus gallus	70.03	9.00e-131	459.00
IUUC-Gac-041463	Gasterosteus aculeatus	51.88	3.00e-84	305.00
IUUC-Ggo-045120	Gorilla gorilla	92.71	5.00e-176	609.00
IUUC-Hsa-046247	Homo sapiens	93.29	4.00e-177	613.00
IUUC-Itr-048292	Ictidomys tridecemlineatus	93.88	1.00e-174	605.00
IUUC-Lch-049741	Latimeria chalumnae	64.56	1.00e-109	389.00
IUUC-Loc-052695	Lepisosteus oculatus	57.73	5.00e-105	374.00
IUUC-Laf-054535	Loxodonta africana	90.26	6.00e-173	599.00
IUUC-Mcc-054699	Macaca mulatta	94.17	2.00e-178	618.00
IUUC-Meu-056053	Macropus eugenii	76.11	2.00e-134	471.00
IUUC-Mga-059672	Meleagris gallopavo	64.10	8.00e-71	259.00
IUUC-Mmr-060963	Microcebus murinus	95.34	0.00e+00	627.00
IUUC-Mdo-062694	Monodelphis domestica	72.97	1.00e-129	456.00
IUUC-Mmu-064031	Mus musculus	90.38	9.00e-173	598.00
IUUC-Mpu-066408	Mustela putorius furo	93.59	1.00e-177	615.00
IUUC-Mlu-068184	Myotis lucifugus	91.25	4.00e-174	603.00
IUUC-Nle-069251	Nomascus leucogenys	93.88	3.00e-178	617.00
IUUC-Opr-071156	Ochotona princeps	85.42	5.00e-162	563.00
IUUC-Ont-072683	Oreochromis niloticus	55.59	3.00e-94	338.00
IUUC-Oan-073042	Ornithorhynchus anatinus	75.43	4.00e-126	444.00
IUUC-Ola-086929	Oryzias latipes	52.47	5.00e-87	313.00
IUUC-Oga-088237	Otolemur garnettii	93.29	2.00e-178	617.00
IUUC-Oar-089312	Ovis aries	93.69	4.00e-167	580.00
IUUC-Ptr-091625	Pan troglodytes	93.00	2.00e-176	611.00
IUUC-Pan-091902	Papio anubis	93.27	9.00e-172	595.00
IUUC-Psi-094035	Pelodiscus sinensis	70.95	3.00e-126	444.00
IUUC-Pma-094565	Petromyzon marinus	62.98	9.00e-57	212.00
IUUC-Pfo-097070	Poecilia formosa	52.72	8.00e-89	320.00
IUUC-Pab-098007	Pongo abelii	93.59	1.00e-177	615.00
IUUC-Pca-100513	Procavia capensis	74.53	2.00e-98	352.00
IUUC-Pva-102821	Pteropus vampyrus	87.17	3.00e-161	560.00
IUUC-Rno-105836	Rattus norvegicus	89.68	2.00e-174	604.00
IUUC-Sha-106847	Sarcophilus harrisii	69.92	1.00e-87	316.00
IUUC-Sar-113451	Sorex araneus	85.47	3.00e-163	567.00
IUUC-Ssc-115978	Sus scrofa	91.84	1.00e-169	588.00
IUUC-Tgu-116745	Taeniopygia guttata	69.00	2.00e-95	341.00
IUUC-Tru-117945	Takifugu rubripes	52.32	6.00e-79	287.00
IUUC-Tsy-119059	Tarsius syrichta	91.57	2.00e-92	331.00
IUUC-Tni-120414	Tetraodon nigroviridis	54.01	1.00e-92	333.00
IUUC-Tbe-127559	Tupaia belangeri	96.79	0.00e+00	634.00
IUUC-Ttr-128505	Tursiops truncatus	91.25	3.00e-171	593.00
IUUC-Vpa-130350	Vicugna pacos	92.90	9.00e-99	352.00
IUUC-Xtr-132939	Xenopus tropicalis	61.01	9.00e-112	396.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence