iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053620

UUCD1 version

UUC-LoA-00004

Ensembl Protein ID

ENSLAFP00000000186.3

UniProt Accession

G3SLA9; G3SLA9_LOXAF

Protein Name

Uncharacterized protein

Gene Name

TRIM46

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000000229.3	ENSLAFT00000000228.3	ENSLAFP00000000186.3
ENSLAFG00000000229.3	ENSLAFT00000032136.1	ENSLAFP00000026825.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.10e-07	32.6	33	133

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkw................pglknssskefr................................ 41
           C++C+e++k+ plvlpC H  ++ C   +                p       ++                                  
   Q: 33   CPVCQEMYKQ-PLVLPCTHNVCQACAREVlgqqgyighggdpnseP-------TSPAstpstrsprlsrrtlpksdrldrllksgfgty 113
           ********99.**************977766556677744433332.......332244455556677777777777777777777777 PP
   S: 42   ................CPlC 45
                           CP C
   Q: 114  pgrkrgalhpqvimfpCPAC 133
           77777777788888887777 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MAEGDDIQTL TSIMDALVRI STSMKNMEKE LLCPVCQEMY KQPLVLPCTH NVCQACAREV 60
LGQQGYIGHG GDPNSEPTSP ASTPSTRSPR LSRRTLPKSD RLDRLLKSGF GTYPGRKRGA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTGAGG GTGATGATAT ACAGACCCTC ACTTCCATCA TGGATGCACT GGTCCGCATC 60
AGTGTGAGTT AAGGTGGGGT CGAGGGAAAG GGGAGGGGGA GAACAGGGGT CCGGGGCCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR013320--ConA-like_dom
IPR017903--COS_domain
IPR003961--FN3_dom
IPR013783--Ig-like_fold
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS51262--COS
PS50853--FN3
PS50119--ZF_BBOX
PS00518--ZF_RING_1

Pfam

PF00643--zf-B_box
PF13445--zf-RING_UBOX

SMART

SM00336--BBOX
SM00184--RING

Gene Ontology

GO:1904115--C:axon cytoplasm
GO:0043194--C:axon initial segment
GO:1990769--C:proximal neuron projection
GO:0008270--F:zinc ion binding
GO:0048490--P:anterograde synaptic vesicle transport
GO:0007409--P:axonogenesis
GO:0001578--P:microtubule bundle formation
GO:0001764--P:neuron migration
GO:0099612--P:protein localization to axon

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001433	Ailuropoda melanoleuca	95.01	0.00e+00	1382.00
IUUC-Apl-003350	Anas platyrhynchos	67.25	0.00e+00	985.00
IUUC-Ame-011708	Astyanax mexicanus	60.52	0.00e+00	901.00
IUUC-Bta-012983	Bos taurus	98.03	0.00e+00	1420.00
IUUC-Cja-018992	Callithrix jacchus	96.45	0.00e+00	1412.00
IUUC-Cfa-020108	Canis familiaris	97.86	0.00e+00	1409.00
IUUC-Cpo-022537	Cavia porcellus	96.97	0.00e+00	800.00
IUUC-Csa-023757	Chlorocebus sabaeus	98.16	0.00e+00	1449.00
IUUC-Dre-027914	Danio rerio	59.47	0.00e+00	867.00
IUUC-Dno-029447	Dasypus novemcinctus	98.55	0.00e+00	1454.00
IUUC-Dor-030163	Dipodomys ordii	97.76	0.00e+00	1441.00
IUUC-Eca-033632	Equus caballus	97.76	0.00e+00	1445.00
IUUC-Fca-036188	Felis catus	96.91	0.00e+00	738.00
IUUC-Fal-037431	Ficedula albicollis	72.86	0.00e+00	1060.00
IUUC-Gmo-039199	Gadus morhua	55.06	0.00e+00	770.00
IUUC-Gac-041603	Gasterosteus aculeatus	58.93	0.00e+00	892.00
IUUC-Ggo-045326	Gorilla gorilla	98.03	0.00e+00	1447.00
IUUC-Hsa-046475	Homo sapiens	98.16	0.00e+00	1448.00
IUUC-Itr-048505	Ictidomys tridecemlineatus	98.03	0.00e+00	1457.00
IUUC-Lch-049891	Latimeria chalumnae	64.39	0.00e+00	993.00
IUUC-Mcc-055666	Macaca mulatta	98.29	0.00e+00	1453.00
IUUC-Mmr-060777	Microcebus murinus	98.42	0.00e+00	1429.00
IUUC-Mdo-062526	Monodelphis domestica	92.07	0.00e+00	748.00
IUUC-Mmu-063938	Mus musculus	96.84	0.00e+00	1436.00
IUUC-Mpu-066543	Mustela putorius furo	96.97	0.00e+00	1269.00
IUUC-Mlu-067086	Myotis lucifugus	93.04	0.00e+00	1334.00
IUUC-Nle-070157	Nomascus leucogenys	98.29	0.00e+00	1447.00
IUUC-Ont-071483	Oreochromis niloticus	60.21	0.00e+00	920.00
IUUC-Ocu-073837	Oryctolagus cuniculus	97.24	0.00e+00	1435.00
IUUC-Ola-086452	Oryzias latipes	59.13	0.00e+00	887.00
IUUC-Oga-088518	Otolemur garnettii	97.93	0.00e+00	1180.00
IUUC-Oar-089791	Ovis aries	92.50	0.00e+00	1338.00
IUUC-Ptr-091585	Pan troglodytes	98.16	0.00e+00	1448.00
IUUC-Pan-092902	Papio anubis	96.45	0.00e+00	1449.00
IUUC-Pfo-096276	Poecilia formosa	58.49	0.00e+00	889.00
IUUC-Pab-098589	Pongo abelii	98.16	0.00e+00	1449.00
IUUC-Pva-103153	Pteropus vampyrus	95.39	0.00e+00	1405.00
IUUC-Rno-105322	Rattus norvegicus	96.23	0.00e+00	1001.00
IUUC-Sha-107412	Sarcophilus harrisii	93.29	0.00e+00	1389.00
IUUC-Ssc-115661	Sus scrofa	97.63	0.00e+00	1437.00
IUUC-Tru-117886	Takifugu rubripes	59.51	0.00e+00	914.00
IUUC-Tni-120625	Tetraodon nigroviridis	59.58	0.00e+00	880.00
IUUC-Ttr-129000	Tursiops truncatus	96.05	0.00e+00	1410.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence