iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Itr-048780

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01028827

Gene Name

ATG16L2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000003790.2	ENSSTOT00000003809.2	ENSSTOP00000003414.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.20e-27	94.0	327	362
UBD/Beta-Prp	1.20e-44	152.6	325	610

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           H ++v++++f ++  ll++G+ D+ i++W++  g+l
   Q: 327  HLSEVNAVCFgPNsSLLATGGADCLIHLWNVVGGRL 362
           99*********7779***************987765 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgh 93
           ++h s +++v+f p++sllatg++d  i +w+v  g l   ++l+g  + +t+v+f+p+g+  + +   +++++w +       tl+gh
   Q: 325  DAHLSEVNAVCFGPNSSLLATGGADCLIHLWNVVGGRLeaNQTLEGAGGSITSVDFDPSGSQVLAATYNQAAQLWKVGEARSKETLSGH 413
           689999********************************88899******************9999999********************* PP
   S: 94   edsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtds 182
           +d+v++ +f  +++  v+Gs+drt++ wdl   +c++ t ++ +    c  v + + +++sG++D+++r+Wd++  ++ +      +++
   Q: 414  KDKVTAAKFKLTRHQAVTGSRDRTVKEWDLGRAYCSR-TINVLS---YCNDVVCGDHIIISGHNDQKIRFWDSRGPRCTQVIP--VQGR 496
           ************************************9.666655...4555555556*************************5..589* PP
   S: 183  vyslsfdsngkelvsgsldgtvklwdlqtgec.....vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnss 266
           v+sls+++++ +l+ +s+d+t+k+ dl+ +++      + +++ +d++k   fsp+  + + gss g ++iWd+++g+l ++lq+++  
   Q: 497  VTSLSLSHDQLHLLICSRDNTLKVIDLRVSNIrqvfrADGFKCGSDWTK-AVFSPDRSYALAGSSNGALYIWDVDTGKLESSLQGPHCA 584
           ****************************888833334444555556666.8899*********************************88 PP
   S: 267  visvavlsfgdnvlvlgsedskvniw 292
            i   +++ +++++v++++  kv +w
   Q: 585  AINAVAWCCSGSHVVSVDQGRKVVLW 610
           888888899**********9999999 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

PTSGWKCHIV RQLQQRDRTQ KALFLELVPA YNHLLEKAEL LAKFSEKLHM KPNDVTSATH 60
QSFWEESGPD SDQSSPQDTL RVKWQKEEEE GLRLDCGEMA YQVVKKSAAL DALQSELEER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCACCTCGG GTTGGAAGTG CCACATTGTG CGGCAGCTAC AGCAGCGGGA CCGCACGCAG 60
AAGGCACTTT TCCTGGAGCT GGTGCCGGCC TGTGAGTGTG CCCTTGGGCA TCTTAGAAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR013923--Autophagy-rel_prot_16
IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08614--ATG16
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0039689--P:negative stranded viral RNA replication

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001470	Ailuropoda melanoleuca	67.05	0.00e+00	745.00
IUUC-Ame-011152	Astyanax mexicanus	42.05	8.00e-119	420.00
IUUC-Bta-013118	Bos taurus	82.30	0.00e+00	896.00
IUUC-Cja-020002	Callithrix jacchus	85.18	0.00e+00	920.00
IUUC-Cfa-020878	Canis familiaris	81.32	0.00e+00	902.00
IUUC-Cpo-022476	Cavia porcellus	81.48	0.00e+00	897.00
IUUC-Csa-024134	Chlorocebus sabaeus	85.62	0.00e+00	917.00
IUUC-Cho-024853	Choloepus hoffmanni	69.01	8.00e-178	616.00
IUUC-Dre-027949	Danio rerio	41.64	2.00e-128	452.00
IUUC-Dno-029683	Dasypus novemcinctus	83.93	0.00e+00	791.00
IUUC-Dor-030897	Dipodomys ordii	77.91	0.00e+00	905.00
IUUC-Ete-032957	Echinops telfairi	93.20	1.00e-130	459.00
IUUC-Eca-033303	Equus caballus	91.64	1.00e-167	582.00
IUUC-Eeu-035336	Erinaceus europaeus	73.76	5.00e-154	537.00
IUUC-Fca-036232	Felis catus	83.63	0.00e+00	964.00
IUUC-Gmo-038880	Gadus morhua	50.00	3.00e-69	255.00
IUUC-Ggo-045130	Gorilla gorilla	92.82	0.00e+00	703.00
IUUC-Hsa-046359	Homo sapiens	87.48	0.00e+00	906.00
IUUC-Lch-050669	Latimeria chalumnae	53.78	4.00e-93	334.00
IUUC-Loc-052789	Lepisosteus oculatus	42.65	6.00e-116	410.00
IUUC-Laf-053699	Loxodonta africana	82.71	0.00e+00	891.00
IUUC-Mcc-055657	Macaca mulatta	80.98	0.00e+00	823.00
IUUC-Meu-056639	Macropus eugenii	49.41	3.00e-114	405.00
IUUC-Mmr-061314	Microcebus murinus	78.47	0.00e+00	822.00
IUUC-Mdo-061841	Monodelphis domestica	64.17	0.00e+00	704.00
IUUC-Mmu-064065	Mus musculus	83.86	0.00e+00	962.00
IUUC-Mpu-066742	Mustela putorius furo	82.35	0.00e+00	889.00
IUUC-Mlu-067019	Myotis lucifugus	88.56	0.00e+00	678.00
IUUC-Nle-069037	Nomascus leucogenys	87.48	0.00e+00	955.00
IUUC-Opr-071039	Ochotona princeps	81.48	0.00e+00	887.00
IUUC-Oan-073431	Ornithorhynchus anatinus	72.53	8.00e-139	486.00
IUUC-Ocu-074772	Oryctolagus cuniculus	84.42	0.00e+00	843.00
IUUC-Ola-086964	Oryzias latipes	51.22	3.00e-80	291.00
IUUC-Oga-088188	Otolemur garnettii	84.12	0.00e+00	903.00
IUUC-Oar-090231	Ovis aries	78.11	0.00e+00	884.00
IUUC-Ptr-091434	Pan troglodytes	84.89	0.00e+00	865.00
IUUC-Pan-091868	Papio anubis	86.39	0.00e+00	905.00
IUUC-Psi-093652	Pelodiscus sinensis	64.58	2.00e-166	578.00
IUUC-Pfo-096960	Poecilia formosa	41.75	3.00e-103	369.00
IUUC-Pab-097776	Pongo abelii	86.49	0.00e+00	872.00
IUUC-Pca-100220	Procavia capensis	65.02	5.00e-172	597.00
IUUC-Pva-103135	Pteropus vampyrus	85.62	0.00e+00	860.00
IUUC-Rno-105529	Rattus norvegicus	82.49	0.00e+00	973.00
IUUC-Sha-107062	Sarcophilus harrisii	64.75	0.00e+00	728.00
IUUC-Sar-113109	Sorex araneus	83.19	2.00e-101	362.00
IUUC-Ssc-115271	Sus scrofa	82.68	0.00e+00	880.00
IUUC-Ttr-128267	Tursiops truncatus	81.48	0.00e+00	847.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence