iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-022187

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02053384

Gene Name

OTUB2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000022719.1	ENSCPOT00000025160.1	ENSCPOP00000019209.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/OTU	5.30e-46	156.4	42	231

Active Site

Position(s)	Description	Evidence
49	N/A	{ECO:0000256\|PIRSR:PIRSR013503-1}
52	Nucleophile	{ECO:0000256\|PIRSR:PIRSR013503-1}
225		{ECO:0000256\|PIRSR:PIRSR013503-1}

Domain Profile

DUB/OTU

   S: 2    lilktkgDGnCLlrAvsqs..........................................................llgvfdddslsd 32
           +i+kt+gDGnC++rA+++s                                                          ll vf+d+s sd
   Q: 42   AIRKTRGDGNCFYRALGYSylesllgksreilkfkervlqtpndllaagfeehkfqnffnafysvvelvekdgsvssLLTVFNDQSFSD 130
           79*************************************************************************************** PP
   S: 33   alveaLreltseylqkesdffsefieekedekefcqklvepeak.geeihifaLaqiLsrpiivvdvdsleskvggillpllfpeeklk 120
            +v++Lr+lts+++++++dff++f++e++d+k+fc+++vep+a  +++i+i+aL+q+L+++++v++vd++++    +l++++fpe++  
   Q: 131  RIVQFLRLLTSAFIRNRADFFRHFVDEEMDIKDFCTHEVEPMAMeCDHIQITALSQALNIALQVEYVDEMDT----ALNHHVFPEAA-I 214
           **********************************************************************95....***********.* PP
   S: 121  kpivLlYrsgHYdaLva 137
           +++ LlY+++HY++L+a
   Q: 215  PSVFLLYKTSHYNILYA 231
           ***************97 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

FQSETSFNLI SEKCDILSIL RDHPENRIYQ RKIQELSKRF TAIRKTRGDG NCFYRALGYS 60
YLESLLGKSR EILKFKERVL QTPNDLLAAG FEEHKFQNFF NAFYSVVELV EKDGSVSSLL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTCAGAGTG AAACATCTTT CAACCTAATA TCAGAAAAAT GCGACATTCT ATCCATTCTT 60
CGTGATCATC CTGAAAACAG GATTTACCAG AGGAAAATCC AGGTGAGGCA GAGGGTGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003323--OTU_dom
IPR030299--OTUB2
IPR016615--Otubain
IPR019400--Peptidase_C65_otubain

PROSITE

PS50802--OTU

Pfam

PF10275--Peptidase_C65

Gene Ontology

GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0035871--P:protein K11-linked deubiquitination
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002059	Ailuropoda melanoleuca	94.85	1.00e-131	461.00
IUUC-Bta-012766	Bos taurus	96.14	3.00e-133	467.00
IUUC-Cja-019480	Callithrix jacchus	92.70	2.00e-128	451.00
IUUC-Cfa-021106	Canis familiaris	95.28	2.00e-132	464.00
IUUC-Csa-023493	Chlorocebus sabaeus	94.47	2.00e-131	461.00
IUUC-Cho-024411	Choloepus hoffmanni	76.10	1.00e-84	305.00
IUUC-Dno-029346	Dasypus novemcinctus	95.69	1.00e-131	461.00
IUUC-Dor-031012	Dipodomys ordii	96.14	6.00e-134	469.00
IUUC-Ete-032266	Echinops telfairi	85.78	1.00e-117	415.00
IUUC-Eca-033356	Equus caballus	97.00	1.00e-133	468.00
IUUC-Eeu-034775	Erinaceus europaeus	95.69	5.00e-132	462.00
IUUC-Fca-035363	Felis catus	93.99	1.00e-130	457.00
IUUC-Ggo-045023	Gorilla gorilla	93.99	8.00e-130	455.00
IUUC-Hsa-046984	Homo sapiens	94.42	2.00e-130	457.00
IUUC-Itr-048012	Ictidomys tridecemlineatus	94.85	4.00e-132	463.00
IUUC-Lch-050514	Latimeria chalumnae	61.33	2.00e-83	301.00
IUUC-Loc-052003	Lepisosteus oculatus	50.66	4.00e-64	237.00
IUUC-Laf-054382	Loxodonta africana	94.42	7.00e-131	459.00
IUUC-Mcc-055516	Macaca mulatta	94.02	1.00e-130	458.00
IUUC-Meu-056038	Macropus eugenii	86.77	1.00e-98	352.00
IUUC-Mmr-060918	Microcebus murinus	96.14	3.00e-133	466.00
IUUC-Mdo-062638	Monodelphis domestica	89.22	2.00e-124	437.00
IUUC-Mmu-063973	Mus musculus	95.32	2.00e-133	468.00
IUUC-Mpu-066013	Mustela putorius furo	95.26	8.00e-132	462.00
IUUC-Mlu-067509	Myotis lucifugus	93.56	1.00e-128	452.00
IUUC-Nle-069673	Nomascus leucogenys	94.42	2.00e-130	457.00
IUUC-Opr-070761	Ochotona princeps	87.27	2.00e-80	291.00
IUUC-Oan-072922	Ornithorhynchus anatinus	81.66	5.00e-112	396.00
IUUC-Ocu-074643	Oryctolagus cuniculus	94.85	2.00e-131	461.00
IUUC-Oni-082026	Oryza nivara	29.95	5.00e-15	75.50
IUUC-Oru-084761	Oryza rufipogon	29.95	5.00e-15	75.50
IUUC-Ola-086603	Oryzias latipes	45.37	7.00e-51	193.00
IUUC-Oga-088936	Otolemur garnettii	94.87	3.00e-132	463.00
IUUC-Oar-089460	Ovis aries	96.60	9.00e-135	472.00
IUUC-Ptr-090805	Pan troglodytes	93.99	5.00e-130	456.00
IUUC-Pan-091969	Papio anubis	94.42	2.00e-130	457.00
IUUC-Pab-098476	Pongo abelii	94.04	5.00e-131	459.00
IUUC-Pca-100252	Procavia capensis	92.00	2.00e-53	201.00
IUUC-Pva-102204	Pteropus vampyrus	94.85	1.00e-131	461.00
IUUC-Pgr-103552	Puccinia graminis	68.75	5.20e-02	30.40
IUUC-Rno-105062	Rattus norvegicus	94.85	7.00e-132	462.00
IUUC-Sha-106968	Sarcophilus harrisii	89.18	5.00e-124	436.00
IUUC-Sar-113295	Sorex araneus	95.69	8.00e-130	455.00
IUUC-Ssc-115288	Sus scrofa	96.98	2.00e-133	467.00
IUUC-Tni-120440	Tetraodon nigroviridis	40.26	4.00e-43	167.00
IUUC-Tbe-127717	Tupaia belangeri	95.27	4.00e-78	282.00
IUUC-Ttr-128221	Tursiops truncatus	76.72	1.00e-99	355.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence