iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066087

Ensembl Protein ID

ENSMPUP00000009943.1

UniProt Accession

M3YF36; M3YF36_MUSPF

Genbank Protein ID

ENSMPUP00000009943

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01035470

Gene Name

RFWD3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000010018.1	ENSMPUT00000010103.1	ENSMPUP00000009943.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-07	31.3	494	532

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sd.tllvsGsdDgtikvWDlrtgvllk 37
           H   +++laf   + +ll+s+s D+t+k+ +l t+++++
   Q: 494  HGKQIRGLAFssRSkGLLLSASLDNTVKLTSLETNTVVQ 532
           8889******99446*************98888877766 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MAQEAMEYHL DGQLELHVAE QPVPAEVVSG QGGPPLLQPL PTQVASSQRE PPLHQPAPDG 60
GTSSQVGLPQ LPPATQMSVD LTEEVELLGE DRVGNVNPGA SEEHRQQSRV NHPIPVSSLD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGATGGCTCA GGAAGCAATG GAATATCATC TTGATGGGCA ATTAGAGCTT CACGTAGCAG 60
AACAGCCTGT TCCTGCTGAA GTAGTCAGCG GCCAAGGGGG GCCACCCCTG CTCCAGCCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING
SM00320--WD40

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0035861--C:site of double-strand break
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0031571--P:mitotic G1 DNA damage checkpoint
GO:2000001--P:regulation of DNA damage checkpoint
GO:0010212--P:response to ionizing radiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000929	Aegilops tauschii	23.91	4.00e-17	82.80
IUUC-Aml-001188	Ailuropoda melanoleuca	90.72	0.00e+00	1299.00
IUUC-Atr-003034	Amborella trichopoda	28.62	3.00e-18	85.50
IUUC-Apl-003182	Anas platyrhynchos	69.86	0.00e+00	722.00
IUUC-Aca-004619	Anolis carolinensis	62.11	0.00e+00	753.00
IUUC-Aly-006391	Arabidopsis lyrata	29.45	1.00e-30	127.00
IUUC-Ath-007300	Arabidopsis thaliana	24.77	1.00e-29	124.00
IUUC-Ame-010890	Astyanax mexicanus	60.04	0.00e+00	628.00
IUUC-Bta-013051	Bos taurus	75.83	0.00e+00	1087.00
IUUC-Bdi-014519	Brachypodium distachyon	26.97	8.00e-20	92.00
IUUC-Bol-015271	Brassica oleracea	29.30	9.00e-30	125.00
IUUC-Bra-017931	Brassica rapa	30.72	1.00e-29	124.00
IUUC-Cja-019240	Callithrix jacchus	76.90	0.00e+00	1114.00
IUUC-Cfa-021010	Canis familiaris	85.79	0.00e+00	1241.00
IUUC-Cpo-022308	Cavia porcellus	72.50	0.00e+00	982.00
IUUC-Csa-023501	Chlorocebus sabaeus	78.15	0.00e+00	1189.00
IUUC-Cho-024900	Choloepus hoffmanni	71.39	0.00e+00	1024.00
IUUC-Cin-025403	Ciona intestinalis	37.40	2.00e-96	346.00
IUUC-Csv-025819	Ciona savignyi	37.21	2.00e-43	169.00
IUUC-Cme-027123	Cyanidioschyzon merolae	25.44	3.00e-17	83.60
IUUC-Dre-028354	Danio rerio	57.35	7.00e-168	583.00
IUUC-Dno-029400	Dasypus novemcinctus	75.96	0.00e+00	1103.00
IUUC-Dor-030320	Dipodomys ordii	72.70	0.00e+00	842.00
IUUC-Dme-031949	Drosophila melanogaster	28.43	5.00e-47	182.00
IUUC-Ete-032691	Echinops telfairi	59.33	4.00e-143	501.00
IUUC-Eca-034320	Equus caballus	82.84	0.00e+00	1242.00
IUUC-Fca-035732	Felis catus	83.02	0.00e+00	1170.00
IUUC-Fal-036648	Ficedula albicollis	61.60	0.00e+00	736.00
IUUC-Gmo-038609	Gadus morhua	58.00	2.00e-140	492.00
IUUC-Gga-040522	Gallus gallus	68.23	4.00e-109	388.00
IUUC-Gac-042318	Gasterosteus aculeatus	54.48	9.00e-134	469.00
IUUC-Gma-043184	Glycine max	27.46	2.00e-26	114.00
IUUC-Ggo-044464	Gorilla gorilla	78.02	0.00e+00	1176.00
IUUC-Hsa-045991	Homo sapiens	78.02	0.00e+00	1173.00
IUUC-Hvu-047705	Hordeum vulgare	24.81	1.00e-28	121.00
IUUC-Itr-047977	Ictidomys tridecemlineatus	82.47	0.00e+00	1190.00
IUUC-Lch-050112	Latimeria chalumnae	57.33	0.00e+00	671.00
IUUC-Lpe-051605	Leersia perrieri	27.80	2.00e-18	87.80
IUUC-Loc-052241	Lepisosteus oculatus	63.05	0.00e+00	648.00
IUUC-Laf-054559	Loxodonta africana	79.11	0.00e+00	991.00
IUUC-Mcc-055093	Macaca mulatta	77.76	0.00e+00	1178.00
IUUC-Meu-056417	Macropus eugenii	66.93	0.00e+00	693.00
IUUC-Mtr-058533	Medicago truncatula	25.00	2.00e-29	124.00
IUUC-Mga-059498	Meleagris gallopavo	69.35	0.00e+00	697.00
IUUC-Mmr-061782	Microcebus murinus	79.44	0.00e+00	1159.00
IUUC-Mdo-062053	Monodelphis domestica	62.87	0.00e+00	822.00
IUUC-Mmu-063352	Mus musculus	67.53	0.00e+00	990.00
IUUC-Mac-064582	Musa acuminata	26.19	4.00e-19	89.70
IUUC-Mlu-068147	Myotis lucifugus	75.03	0.00e+00	1055.00
IUUC-Nle-069503	Nomascus leucogenys	74.42	0.00e+00	1108.00
IUUC-Opr-070479	Ochotona princeps	67.96	0.00e+00	998.00
IUUC-Ont-071700	Oreochromis niloticus	57.06	9.00e-169	587.00
IUUC-Oan-073702	Ornithorhynchus anatinus	74.49	0.00e+00	791.00
IUUC-Ocu-074886	Oryctolagus cuniculus	72.31	0.00e+00	1093.00
IUUC-Oba-075729	Oryza barthii	25.67	3.00e-24	106.00
IUUC-Obr-076562	Oryza brachyantha	28.90	2.00e-20	94.00
IUUC-Ogl-077615	Oryza glaberrima	25.67	3.00e-24	106.00
IUUC-Ogu-078921	Oryza glumaepatula	25.67	7.00e-25	108.00
IUUC-Oin-079250	Oryza indica	25.16	7.00e-16	78.60
IUUC-Olo-080758	Oryza longistaminata	24.95	1.00e-23	104.00
IUUC-Ome-081707	Oryza meridionalis	25.78	9.00e-18	85.10
IUUC-Oni-083006	Oryza nivara	25.67	1.00e-24	108.00
IUUC-Opu-083650	Oryza punctata	26.00	9.00e-25	108.00
IUUC-Oru-084924	Oryza rufipogon	25.53	4.00e-25	109.00
IUUC-Osa-085820	Oryza sativa	25.67	1.00e-24	108.00
IUUC-Ola-087229	Oryzias latipes	56.67	2.00e-137	481.00
IUUC-Oga-088243	Otolemur garnettii	75.67	0.00e+00	1068.00
IUUC-Oar-089461	Ovis aries	78.31	0.00e+00	1165.00
IUUC-Ptr-090527	Pan troglodytes	78.15	0.00e+00	1171.00
IUUC-Pan-092431	Papio anubis	77.70	0.00e+00	1098.00
IUUC-Psi-093156	Pelodiscus sinensis	72.43	0.00e+00	770.00
IUUC-Pno-094897	Phaeosphaeria nodorum	23.73	1.00e-07	50.40
IUUC-Ppa-095305	Physcomitrella patens	37.01	9.00e-20	92.80
IUUC-Pfo-097065	Poecilia formosa	58.33	8.00e-166	577.00
IUUC-Pab-098272	Pongo abelii	78.28	0.00e+00	1193.00
IUUC-Pop-099827	Populus trichocarpa	30.74	5.00e-30	125.00
IUUC-Pca-100713	Procavia capensis	66.49	0.00e+00	944.00
IUUC-Ppe-102103	Prunus persica	25.05	1.00e-31	131.00
IUUC-Pva-103133	Pteropus vampyrus	88.14	0.00e+00	777.00
IUUC-Pte-104191	Pyrenophora teres	50.00	3.00e-08	52.80
IUUC-Pyt-104734	Pyrenophora triticirepentis	48.00	5.00e-08	51.60
IUUC-Sha-107628	Sarcophilus harrisii	60.77	0.00e+00	816.00
IUUC-Sit-109781	Setaria italica	30.39	3.00e-24	106.00
IUUC-Sly-111779	Solanum lycopersicum	31.27	1.00e-29	125.00
IUUC-Stu-112817	Solanum tuberosum	44.25	1.00e-19	90.10
IUUC-Sar-113124	Sorex araneus	69.51	0.00e+00	688.00
IUUC-Sbi-114107	Sorghum bicolor	25.73	2.00e-28	120.00
IUUC-Ssc-115850	Sus scrofa	80.28	0.00e+00	1166.00
IUUC-Tgu-117295	Taeniopygia guttata	70.41	0.00e+00	743.00
IUUC-Tru-117539	Takifugu rubripes	57.31	3.00e-169	588.00
IUUC-Tsy-118805	Tarsius syrichta	69.83	1.00e-112	400.00
IUUC-Tni-120274	Tetraodon nigroviridis	58.18	2.00e-168	585.00
IUUC-Tca-121162	Theobroma cacao	33.33	9.00e-31	128.00
IUUC-Tae-124822	Triticum aestivum	26.40	2.00e-29	124.00
IUUC-Tur-126162	Triticum urartu	23.98	5.00e-18	86.70
IUUC-Tbe-127884	Tupaia belangeri	72.32	2.00e-84	306.00
IUUC-Ttr-128665	Tursiops truncatus	72.77	2.00e-156	546.00
IUUC-Vpa-130385	Vicugna pacos	84.39	0.00e+00	1199.00
IUUC-Vvi-131464	Vitis vinifera	28.25	1.00e-23	104.00
IUUC-Xtr-132015	Xenopus tropicalis	62.19	0.00e+00	722.00
IUUC-Xma-133109	Xiphophorus maculatus	58.12	4.00e-165	575.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence