iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
RAID2
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	1.60e-17	64.0	137	206

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvg....geeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           aDv ++vg     ++++ahk+vLa  SsvFya+f+++l e   k++++i dv+p +f +llk++Y++++d++
   Q: 137  ADVHFIVGalgaARRVPAHKYVLAVGSSVFYAMFYGDLAEV--KSEIHIPDVEPAAFLVLLKYMYSDEIDLE 206
           699****666689***************************9..5*************************985 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MLLPLACLHG RVAQCLTYLL GLAEPLPKPR RGAKARGAVL TSAEAAPAGA KMAAELYPPA 60
GASAATATDI ANSNAAGAAE STKVGLCCPP CLAPAPLPPL PAPPLPDNNN PESPNWQSFH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGGGACGGC GCCCCCTGCG GCCCGGCCGC GGGCTCGGTG CGGGGTGTGG GGTGCGGGTG 60
GGCGGCGGGC AGGGCCAGCG CGGCCCCATG CTGCTGCCGC TCGCCTGCCT GCATGGGCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR012983--PHR
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF08005--PHR

SMART

SM00875--BACK
SM00225--BTB

Gene Ontology

GO:0005829--C:cytosol
GO:0019005--C:SCF ubiquitin ligase complex
GO:0031625--F:ubiquitin protein ligase binding
GO:0022008--P:neurogenesis
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0030162--P:regulation of proteolysis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001698	Ailuropoda melanoleuca	95.48	0.00e+00	829.00
IUUC-Apl-003687	Anas platyrhynchos	80.11	0.00e+00	858.00
IUUC-Aca-004837	Anolis carolinensis	92.99	0.00e+00	842.00
IUUC-Ame-010962	Astyanax mexicanus	87.50	0.00e+00	785.00
IUUC-Bta-013321	Bos taurus	95.61	0.00e+00	815.00
IUUC-Cja-018819	Callithrix jacchus	94.69	0.00e+00	850.00
IUUC-Cfa-020312	Canis familiaris	93.90	0.00e+00	797.00
IUUC-Cpo-021713	Cavia porcellus	97.23	0.00e+00	882.00
IUUC-Csa-023707	Chlorocebus sabaeus	96.10	0.00e+00	822.00
IUUC-Dre-028757	Danio rerio	87.53	0.00e+00	787.00
IUUC-Dno-029600	Dasypus novemcinctus	96.23	0.00e+00	749.00
IUUC-Eca-033474	Equus caballus	96.54	0.00e+00	868.00
IUUC-Fca-036108	Felis catus	95.12	0.00e+00	810.00
IUUC-Fal-037012	Ficedula albicollis	93.59	0.00e+00	830.00
IUUC-Gmo-038628	Gadus morhua	84.47	0.00e+00	757.00
IUUC-Gga-040672	Gallus gallus	79.67	0.00e+00	853.00
IUUC-Gac-041592	Gasterosteus aculeatus	78.07	0.00e+00	775.00
IUUC-Ggo-044914	Gorilla gorilla	91.10	0.00e+00	854.00
IUUC-Hsa-046005	Homo sapiens	94.68	0.00e+00	853.00
IUUC-Itr-048159	Ictidomys tridecemlineatus	97.90	0.00e+00	877.00
IUUC-Lch-049492	Latimeria chalumnae	89.31	0.00e+00	797.00
IUUC-Loc-052121	Lepisosteus oculatus	78.50	0.00e+00	843.00
IUUC-Laf-054023	Loxodonta africana	97.34	0.00e+00	844.00
IUUC-Mcc-055221	Macaca mulatta	96.34	0.00e+00	825.00
IUUC-Meu-056880	Macropus eugenii	90.24	0.00e+00	788.00
IUUC-Mga-059788	Meleagris gallopavo	92.76	0.00e+00	832.00
IUUC-Mmr-061333	Microcebus murinus	96.34	0.00e+00	824.00
IUUC-Mdo-062071	Monodelphis domestica	89.58	0.00e+00	828.00
IUUC-Mmu-064273	Mus musculus	97.59	0.00e+00	960.00
IUUC-Mpu-065966	Mustela putorius furo	94.15	0.00e+00	807.00
IUUC-Mlu-066940	Myotis lucifugus	93.03	0.00e+00	813.00
IUUC-Nle-070099	Nomascus leucogenys	96.10	0.00e+00	822.00
IUUC-Opr-070931	Ochotona princeps	94.88	0.00e+00	814.00
IUUC-Ont-071493	Oreochromis niloticus	87.85	0.00e+00	795.00
IUUC-Ocu-074781	Oryctolagus cuniculus	94.88	0.00e+00	815.00
IUUC-Ola-086691	Oryzias latipes	77.47	0.00e+00	815.00
IUUC-Oga-088166	Otolemur garnettii	95.33	0.00e+00	853.00
IUUC-Oar-090170	Ovis aries	93.05	0.00e+00	803.00
IUUC-Pan-092894	Papio anubis	90.93	0.00e+00	844.00
IUUC-Psi-093858	Pelodiscus sinensis	93.11	0.00e+00	832.00
IUUC-Pfo-096949	Poecilia formosa	86.37	0.00e+00	796.00
IUUC-Pca-100556	Procavia capensis	96.61	0.00e+00	774.00
IUUC-Sha-107182	Sarcophilus harrisii	89.12	0.00e+00	822.00
IUUC-Tgu-117158	Taeniopygia guttata	78.42	0.00e+00	835.00
IUUC-Tru-118020	Takifugu rubripes	85.28	0.00e+00	760.00
IUUC-Tni-120203	Tetraodon nigroviridis	81.71	0.00e+00	744.00
IUUC-Tbe-127750	Tupaia belangeri	91.65	0.00e+00	775.00
IUUC-Ttr-128417	Tursiops truncatus	94.52	0.00e+00	748.00
IUUC-Xtr-132362	Xenopus tropicalis	77.82	0.00e+00	837.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence