iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062940

UUCD1 version

UUC-MoD-00388

Ensembl Protein ID

ENSMODP00000017698.2

UniProt Accession

F6X2Y9; F6X2Y9_MONDO

Protein Name

Uncharacterized protein

Gene Name

SCAP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000014155.3	ENSMODT00000018026.3	ENSMODP00000017698.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.10e-17	61.5	1126	1159

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsd.tl.lvsGsdDgtikvWDlrtg 33
           gH++ +t++   d t+ l+sG+ Dg i +WD+ tg
   Q: 1126 GHSGAITAVYI-DqTMvLASGGQDGAICLWDVLTG 1159
           8********88.446648*************9887 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

RMTLTERLRD KISRAFYSHG LFCASYPIPI ILFTGFCILA CCYPLLKLPL PGTGPVEYTT 60
PVKDYSPPLS DPDRQQKDRS EQPDWYVGAP VAYIQQIFVK STVSPWHKNL LTVDVFRSPL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTCCTTTTC TGCAGATGGT ATTTGACATC AGTGCCAACC ACAGTGTACC TGGCTAACCT 60
CCTGTTGAAT TCCGTGATGG CAACAAGGTG ACATGAGCTG AGGATGACCC TGACTGAAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0853--WD repeat

Interpro

IPR030225--SCAP
IPR000731--SSD
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50156--SSD
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12349--Sterol-sensing
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0016021--C:integral component of membrane
GO:0015485--F:cholesterol binding
GO:0008203--P:cholesterol metabolic process
GO:0045540--P:regulation of cholesterol biosynthetic process
GO:0042304--P:regulation of fatty acid biosynthetic process
GO:0001666--P:response to hypoxia
GO:0032868--P:response to insulin
GO:0032933--P:SREBP signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001802	Ailuropoda melanoleuca	86.41	0.00e+00	1014.00
IUUC-Apl-003294	Anas platyrhynchos	79.89	0.00e+00	1848.00
IUUC-Aca-004424	Anolis carolinensis	70.86	0.00e+00	1585.00
IUUC-Bta-013478	Bos taurus	80.91	0.00e+00	1837.00
IUUC-Cel-018160	Caenorhabditis elegans	29.05	7.00e-66	246.00
IUUC-Cja-019123	Callithrix jacchus	79.38	0.00e+00	1792.00
IUUC-Cfa-021082	Canis familiaris	80.83	0.00e+00	1818.00
IUUC-Cpo-022477	Cavia porcellus	76.68	0.00e+00	1740.00
IUUC-Csa-023176	Chlorocebus sabaeus	79.21	0.00e+00	1790.00
IUUC-Cin-025490	Ciona intestinalis	36.51	8.00e-89	322.00
IUUC-Csv-026115	Ciona savignyi	37.16	8.00e-132	465.00
IUUC-Dre-028008	Danio rerio	67.61	0.00e+00	1567.00
IUUC-Dno-028887	Dasypus novemcinctus	81.93	0.00e+00	1092.00
IUUC-Dor-030467	Dipodomys ordii	88.87	0.00e+00	840.00
IUUC-Dme-032087	Drosophila melanogaster	33.15	7.00e-113	402.00
IUUC-Ete-032372	Echinops telfairi	68.33	0.00e+00	1512.00
IUUC-Eca-033896	Equus caballus	82.16	0.00e+00	1954.00
IUUC-Eeu-035099	Erinaceus europaeus	74.56	0.00e+00	1064.00
IUUC-Fca-035616	Felis catus	77.34	0.00e+00	1765.00
IUUC-Fal-037231	Ficedula albicollis	76.44	0.00e+00	1766.00
IUUC-Gmo-039439	Gadus morhua	73.18	0.00e+00	678.00
IUUC-Gac-041516	Gasterosteus aculeatus	65.51	0.00e+00	1554.00
IUUC-Hsa-046674	Homo sapiens	81.47	0.00e+00	1898.00
IUUC-Itr-048879	Ictidomys tridecemlineatus	81.31	0.00e+00	1888.00
IUUC-Lch-049689	Latimeria chalumnae	73.48	0.00e+00	1751.00
IUUC-Loc-052417	Lepisosteus oculatus	55.10	6.00e-151	527.00
IUUC-Laf-053795	Loxodonta africana	80.96	0.00e+00	1886.00
IUUC-Mcc-055502	Macaca mulatta	81.45	0.00e+00	1887.00
IUUC-Mga-059805	Meleagris gallopavo	80.70	0.00e+00	1850.00
IUUC-Mmr-060997	Microcebus murinus	81.70	0.00e+00	1927.00
IUUC-Mmu-063255	Mus musculus	81.84	0.00e+00	1890.00
IUUC-Mpu-066158	Mustela putorius furo	81.26	0.00e+00	1890.00
IUUC-Mlu-067201	Myotis lucifugus	78.11	0.00e+00	1828.00
IUUC-Nle-069145	Nomascus leucogenys	83.05	0.00e+00	1199.00
IUUC-Opr-070797	Ochotona princeps	77.01	0.00e+00	1749.00
IUUC-Ont-071553	Oreochromis niloticus	66.92	0.00e+00	1550.00
IUUC-Ocu-074598	Oryctolagus cuniculus	81.53	0.00e+00	1870.00
IUUC-Ola-086650	Oryzias latipes	84.68	1.00e-112	398.00
IUUC-Oar-089287	Ovis aries	77.28	0.00e+00	991.00
IUUC-Pan-092004	Papio anubis	81.23	0.00e+00	1859.00
IUUC-Psi-093028	Pelodiscus sinensis	74.86	0.00e+00	1634.00
IUUC-Pma-094145	Petromyzon marinus	48.90	0.00e+00	1129.00
IUUC-Pfo-096320	Poecilia formosa	66.59	0.00e+00	1551.00
IUUC-Pab-097862	Pongo abelii	81.76	0.00e+00	1902.00
IUUC-Pca-100862	Procavia capensis	69.85	0.00e+00	1495.00
IUUC-Pva-103050	Pteropus vampyrus	80.41	0.00e+00	1176.00
IUUC-Rno-105852	Rattus norvegicus	81.84	0.00e+00	1894.00
IUUC-Sha-107312	Sarcophilus harrisii	93.63	0.00e+00	2192.00
IUUC-Sar-113311	Sorex araneus	78.30	0.00e+00	746.00
IUUC-Ssc-116356	Sus scrofa	81.54	0.00e+00	1929.00
IUUC-Tgu-116896	Taeniopygia guttata	64.74	0.00e+00	629.00
IUUC-Tru-118197	Takifugu rubripes	66.24	0.00e+00	1538.00
IUUC-Tni-119823	Tetraodon nigroviridis	64.33	0.00e+00	1511.00
IUUC-Ttr-129164	Tursiops truncatus	81.39	0.00e+00	1849.00
IUUC-Xtr-132819	Xenopus tropicalis	70.71	0.00e+00	1709.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence