iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-073800

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02036334

Gene Name

HECTD2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000015035.3	ENSOCUT00000015038.3	ENSOCUP00000012922.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.20e-102	343.8	324	662

Active Site

Position(s)	Description	Evidence
630	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           ++dlkk+l+v+fvgE+gld+gG+t+e++ ll++++++pd+g+f+y+++++++++ + +      ++ + F+++G+l+g+a++++  ld+
   Q: 324  RADLKKKLKVTFVGEAGLDMGGLTKEWFLLLIRQIFHPDYGMFTYHKDSHCHWFSSFKC-----DNYSEFRLVGILMGLAVYNSITLDI 407
           589***************************************************87766.....789********************** PP
   S: 91   plsksfyklllgk..............klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipV 165
           ++++++yk+ll+               +++++dl +++pel++ l e++++ e ++ee  +  tf+v +e++g +k+++Lkp+G++i V
   Q: 408  RFPPCCYKKLLSPpivpsdqnipvgicSVTIDDLYQIMPELAHGLSELLSY-EGNVEED-FYSTFQVFQEEFGIIKSYNLKPSGDKITV 494
           *************666666666666555**********************9.6788885.***************************** PP
   S: 166  tneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevle 254
           tn+N++eYv+l++++ l+++i +q++af+ Gf++v+  + l l+++ee+e+l+cG++e+d+++l++ t+y+g y +++ +i++Fw+v+ 
   Q: 495  TNQNRKEYVQLYTDFLLNKSIYKQFAAFYYGFHSVCASNALMLLRPEEVEILVCGSPELDMHALQRSTQYDG-YAKTDLTIRYFWDVVL 582
           **********************************************************************76.**************** PP
   S: 255  efsseerkafLqFvTgssrlPlgGfaelkprlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           +f  + +k++L+F+Tgs+r+P+gG+a+l+   f i+k ++s+++lP ++TCfn+L+LP+Y+sk+ lk+kL++ i++++gF+l+
   Q: 583  GFPLDLQKKLLHFTTGSDRVPVGGMADLN---FKISKnETSTNWLPVAHTCFNQLCLPPYKSKKDLKQKLIIGISNAEGFGLE 662
           *****************************...9999967777**************************************985 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MKAPALPEPT LPIQSKTMKD FQEDIEKVKS SGDWKAVHDF YLTTFDSFPQ LNAAFKKDAT 60
APFNSIEDSG INAKFVNAVY DALLNTPQDI QKTVLKGIIN SLLREWKGPR TKDDLRAYFI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGAGCGCGG GTGGGGGCGG AGCGGCGGCG GAGGTCGCGG CGGTTGCCAG CGGCGGCCCA 60
GACCCCTCCG GCGGCGACGG CCGCCGCCTT CCCACCCTCC GGTTCTTTTC CTGCTTCTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

KEGG

ocu:100345359

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001266	Ailuropoda melanoleuca	96.70	0.00e+00	1319.00
IUUC-Apl-003589	Anas platyrhynchos	88.22	0.00e+00	1192.00
IUUC-Aca-004350	Anolis carolinensis	84.29	0.00e+00	1153.00
IUUC-Ago-007908	Ashbya gossypii	34.66	6.00e-80	292.00
IUUC-Acl-008288	Aspergillus clavatus	34.70	5.00e-93	336.00
IUUC-Afl-008402	Aspergillus flavus	33.67	2.00e-87	316.00
IUUC-Afu-008762	Aspergillus fumigatus	33.99	2.00e-90	327.00
IUUC-Ani-009176	Aspergillus nidulans	35.67	1.00e-89	324.00
IUUC-Ang-009791	Aspergillus niger	35.87	6.00e-90	325.00
IUUC-Aor-009921	Aspergillus oryzae	33.50	2.00e-86	314.00
IUUC-Ate-010295	Aspergillus terreus	35.59	1.00e-96	348.00
IUUC-Ame-010660	Astyanax mexicanus	82.27	9.00e-153	532.00
IUUC-Bgr-011981	Blumeria graminis	34.96	2.00e-92	333.00
IUUC-Bta-012945	Bos taurus	95.77	0.00e+00	1282.00
IUUC-Bci-013697	Botrytis cinerea	33.06	1.00e-77	285.00
IUUC-Cja-019263	Callithrix jacchus	95.50	0.00e+00	1283.00
IUUC-Cfa-020486	Canis familiaris	97.05	0.00e+00	1291.00
IUUC-Cpo-021755	Cavia porcellus	96.53	0.00e+00	1319.00
IUUC-Csa-023814	Chlorocebus sabaeus	96.63	0.00e+00	1214.00
IUUC-Cho-024980	Choloepus hoffmanni	77.79	0.00e+00	998.00
IUUC-Cgl-026526	Colletotrichum gloeosporioides	40.93	1.00e-94	341.00
IUUC-Dre-028551	Danio rerio	79.61	0.00e+00	1087.00
IUUC-Dno-029497	Dasypus novemcinctus	94.14	0.00e+00	1230.00
IUUC-Dor-030867	Dipodomys ordii	82.48	0.00e+00	1083.00
IUUC-Dse-031239	Dothistroma septosporum	30.00	4.00e-86	313.00
IUUC-Ete-032902	Echinops telfairi	83.06	0.00e+00	1096.00
IUUC-Eca-033678	Equus caballus	96.37	0.00e+00	1293.00
IUUC-Eeu-035262	Erinaceus europaeus	77.95	0.00e+00	1001.00
IUUC-Fca-035590	Felis catus	96.83	0.00e+00	1321.00
IUUC-Fal-037123	Ficedula albicollis	84.41	0.00e+00	1128.00
IUUC-Fox-037941	Fusarium oxysporum	40.08	1.00e-97	351.00
IUUC-Fso-038388	Fusarium solani	40.87	2.00e-100	360.00
IUUC-Gmo-039553	Gadus morhua	66.30	0.00e+00	847.00
IUUC-Ggr-040110	Gaeumannomyces graminis	40.48	5.00e-96	346.00
IUUC-Gga-040406	Gallus gallus	88.22	0.00e+00	1226.00
IUUC-Gac-042141	Gasterosteus aculeatus	75.98	0.00e+00	1066.00
IUUC-Ggo-045504	Gorilla gorilla	95.35	0.00e+00	1283.00
IUUC-Hsa-045786	Homo sapiens	95.92	0.00e+00	1288.00
IUUC-Itr-048050	Ictidomys tridecemlineatus	90.66	0.00e+00	1185.00
IUUC-Kpa-049152	Komagataella pastoris	33.40	4.00e-72	266.00
IUUC-Lch-049824	Latimeria chalumnae	83.20	0.00e+00	1029.00
IUUC-Loc-052173	Lepisosteus oculatus	83.23	0.00e+00	1149.00
IUUC-Laf-054017	Loxodonta africana	96.22	0.00e+00	1291.00
IUUC-Mcc-055713	Macaca mulatta	96.10	0.00e+00	1288.00
IUUC-Meu-056212	Macropus eugenii	69.75	4.00e-116	412.00
IUUC-Mor-057045	Magnaporthe oryzae	36.21	6.00e-88	319.00
IUUC-Mla-059187	Melampsora laricipopulina	43.31	5.00e-86	311.00
IUUC-Mga-059884	Meleagris gallopavo	80.87	0.00e+00	1068.00
IUUC-Mmr-061344	Microcebus murinus	96.37	0.00e+00	1314.00
IUUC-Mdo-062653	Monodelphis domestica	92.30	0.00e+00	1250.00
IUUC-Mmu-063775	Mus musculus	92.89	0.00e+00	1199.00
IUUC-Mpu-066069	Mustela putorius furo	96.98	0.00e+00	1318.00
IUUC-Mlu-067925	Myotis lucifugus	96.22	0.00e+00	1289.00
IUUC-Nfi-068439	Neosartorya fischeri	33.99	2.00e-90	327.00
IUUC-Ncr-068903	Neurospora crassa	37.47	3.00e-90	327.00
IUUC-Nle-070046	Nomascus leucogenys	95.35	0.00e+00	1308.00
IUUC-Opr-071085	Ochotona princeps	80.54	8.00e-140	490.00
IUUC-Ont-072126	Oreochromis niloticus	77.19	0.00e+00	1093.00
IUUC-Oan-072933	Ornithorhynchus anatinus	89.66	0.00e+00	1181.00
IUUC-Ola-086988	Oryzias latipes	76.32	0.00e+00	1075.00
IUUC-Oga-088117	Otolemur garnettii	97.07	0.00e+00	1128.00
IUUC-Oar-089371	Ovis aries	95.77	0.00e+00	1263.00
IUUC-Ptr-090551	Pan troglodytes	95.35	0.00e+00	1283.00
IUUC-Pan-092067	Papio anubis	96.68	0.00e+00	1293.00
IUUC-Psi-092963	Pelodiscus sinensis	88.97	0.00e+00	1186.00
IUUC-Pfo-096562	Poecilia formosa	75.08	0.00e+00	1071.00
IUUC-Pab-098680	Pongo abelii	96.07	0.00e+00	1288.00
IUUC-Pca-100986	Procavia capensis	76.17	0.00e+00	888.00
IUUC-Pva-102219	Pteropus vampyrus	85.00	0.00e+00	1019.00
IUUC-Pgr-103315	Puccinia graminis	36.67	4.00e-94	339.00
IUUC-Ptt-103736	Puccinia triticina	41.49	4.00e-93	336.00
IUUC-Rno-105270	Rattus norvegicus	93.34	0.00e+00	1202.00
IUUC-Sce-106306	Saccharomyces cerevisiae	34.25	1.00e-66	248.00
IUUC-Sha-106819	Sarcophilus harrisii	93.06	0.00e+00	1274.00
IUUC-Spo-108271	Schizosaccharomyces pombe	32.32	4.00e-84	306.00
IUUC-Ssl-108657	Sclerotinia sclerotiorum	30.81	5.00e-82	299.00
IUUC-Sar-113134	Sorex araneus	86.55	0.00e+00	1116.00
IUUC-Ssc-115441	Sus scrofa	96.08	0.00e+00	1267.00
IUUC-Tgu-117166	Taeniopygia guttata	87.52	0.00e+00	1164.00
IUUC-Tsy-118898	Tarsius syrichta	83.46	0.00e+00	1045.00
IUUC-Tre-122108	Trichoderma reesei	38.64	8.00e-87	315.00
IUUC-Tvi-122644	Trichoderma virens	38.91	6.00e-92	332.00
IUUC-Tme-127004	Tuber melanosporum	34.56	7.00e-101	362.00
IUUC-Tbe-127292	Tupaia belangeri	78.40	0.00e+00	980.00
IUUC-Ttr-128352	Tursiops truncatus	91.84	0.00e+00	1215.00
IUUC-Vda-129969	Verticillium dahliae	40.00	6.00e-91	329.00
IUUC-Vpa-130218	Vicugna pacos	85.94	0.00e+00	1120.00
IUUC-Xtr-132594	Xenopus tropicalis	80.36	0.00e+00	1060.00
IUUC-Xma-134157	Xiphophorus maculatus	74.96	0.00e+00	1000.00
IUUC-Yli-134470	Yarrowia lipolytica	34.55	1.00e-75	278.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence