iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oga-088117

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03020088

Gene Name

HECTD2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000006030.2	ENSOGAT00000006034.2	ENSOGAP00000005392.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	4.20e-103	345.3	242	580

Active Site

Position(s)	Description	Evidence
548	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           ++dlkk+l+v+fvgE+gld+gG+t+e++ ll++++++pd+g+f+y+++++++++ + +      ++ + F+++G+l+g+a++++  ld+
   Q: 242  RADLKKKLKVTFVGEAGLDMGGLTKEWFLLLIRQIFHPDYGMFTYHKDSHCHWFSSFKC-----DNYSEFRLVGILMGLAVYNSITLDI 325
           589***************************************************87766.....789********************** PP
   S: 91   plsksfyklllgk..............klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipV 165
           ++++++yk+ll+               +++++dl +++pel++ l+e++++ e ++ee  +  tf+v +e++g +k+++LkpgG++ipV
   Q: 326  RFPPCCYKKLLSPpivpsdqnipvgicSVTIDDLCQIMPELAHGLTELLSY-EGNVEED-FYSTFQVFQEEFGIIKSYNLKPGGDKIPV 412
           *************666666666666555**********************9.6788885.***************************** PP
   S: 166  tneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevle 254
           t++N++eYv+l++++ l+++i +q+ af+ Gf++v+  + l l+ +ee+e+l+cG++e+d+++l++ t+y+g y +++ +i++Fwev+ 
   Q: 413  TKQNRKEYVQLYIDFLLNKSIYKQFSAFYYGFHSVCASNALMLLCPEEVEILVCGSPELDMHALQRSTQYDG-YAKTDLTIRYFWEVVL 500
           **********************************************************************76.**************** PP
   S: 255  efsseerkafLqFvTgssrlPlgGfaelkprlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           +f  + +k++L+F+Tgs+r+P+gG+a+l+   f i+k ++s+++lP ++TCfn+L+LP+Y+sk+ lk+kL++ i++++gF+l+
   Q: 501  GFPLDLQKKLLHFTTGSDRVPVGGMADLN---FKISKnETSTNWLPVAHTCFNQLCLPPYKSKKDLKQKLIIGISNSEGFGLE 580
           *****************************...9999967777**************************************985 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

PQDIQKTVLK GIINNLLREW KGPRTKDDLR AYFVLLQNPQ FNNTSTYVIY AHLLRQTATL 60
VEADHHFLAH WFKKHFKLLS QKRFKQLVER LLQFISLRLF PAKPEEFPPI TKCSWWIPSA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTCAAGACA TTCAGAAGAC AGTATTAAAG GGAATCATTA ACAATCTTTT ACGAGAATGG 60
AAAGGGTAAT TGTAACCAAT ATTTCCAATA TTTAGCTAAT CAGTATAGAG GTTTAACTTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001266	Ailuropoda melanoleuca	97.24	0.00e+00	1160.00
IUUC-Apl-003589	Anas platyrhynchos	88.28	0.00e+00	1034.00
IUUC-Aca-004350	Anolis carolinensis	87.24	0.00e+00	1033.00
IUUC-Ago-007908	Ashbya gossypii	35.06	7.00e-81	295.00
IUUC-Acl-008288	Aspergillus clavatus	34.85	1.00e-90	328.00
IUUC-Afl-008402	Aspergillus flavus	33.28	2.00e-85	310.00
IUUC-Afu-008762	Aspergillus fumigatus	33.93	4.00e-89	323.00
IUUC-Ani-009176	Aspergillus nidulans	35.59	4.00e-88	319.00
IUUC-Ang-009791	Aspergillus niger	35.30	4.00e-87	316.00
IUUC-Aor-009921	Aspergillus oryzae	33.11	2.00e-84	306.00
IUUC-Ate-010295	Aspergillus terreus	38.46	1.00e-94	341.00
IUUC-Ame-010660	Astyanax mexicanus	81.61	9.00e-151	525.00
IUUC-Bgr-011981	Blumeria graminis	38.22	7.00e-90	325.00
IUUC-Bta-012945	Bos taurus	96.90	0.00e+00	1133.00
IUUC-Bci-013697	Botrytis cinerea	36.26	3.00e-77	283.00
IUUC-Cja-019263	Callithrix jacchus	95.86	0.00e+00	1122.00
IUUC-Cfa-020486	Canis familiaris	96.55	0.00e+00	1149.00
IUUC-Cpo-021755	Cavia porcellus	96.55	0.00e+00	1149.00
IUUC-Csa-023814	Chlorocebus sabaeus	95.56	0.00e+00	1035.00
IUUC-Cho-024980	Choloepus hoffmanni	78.49	0.00e+00	837.00
IUUC-Cgl-026526	Colletotrichum gloeosporioides	41.14	1.00e-94	341.00
IUUC-Dre-028551	Danio rerio	80.34	0.00e+00	951.00
IUUC-Dno-029497	Dasypus novemcinctus	96.55	0.00e+00	1115.00
IUUC-Dor-030867	Dipodomys ordii	81.03	0.00e+00	922.00
IUUC-Dse-031239	Dothistroma septosporum	34.71	2.00e-85	310.00
IUUC-Ete-032902	Echinops telfairi	91.38	0.00e+00	1080.00
IUUC-Eca-033678	Equus caballus	96.55	0.00e+00	1151.00
IUUC-Eeu-035262	Erinaceus europaeus	80.69	0.00e+00	911.00
IUUC-Fca-035590	Felis catus	96.72	0.00e+00	1154.00
IUUC-Fal-037123	Ficedula albicollis	84.27	0.00e+00	973.00
IUUC-Fox-037941	Fusarium oxysporum	40.48	1.00e-98	355.00
IUUC-Fso-038388	Fusarium solani	41.27	2.00e-101	364.00
IUUC-Gmo-039553	Gadus morhua	66.21	0.00e+00	761.00
IUUC-Ggr-040110	Gaeumannomyces graminis	40.67	5.00e-96	346.00
IUUC-Gga-040406	Gallus gallus	88.28	0.00e+00	1065.00
IUUC-Gac-042141	Gasterosteus aculeatus	77.41	0.00e+00	948.00
IUUC-Ggo-045504	Gorilla gorilla	95.34	0.00e+00	1117.00
IUUC-Hsa-045786	Homo sapiens	95.17	0.00e+00	1110.00
IUUC-Itr-048050	Ictidomys tridecemlineatus	90.21	0.00e+00	1023.00
IUUC-Kpa-049152	Komagataella pastoris	33.98	8.00e-75	275.00
IUUC-Lch-049824	Latimeria chalumnae	83.18	0.00e+00	893.00
IUUC-Loc-052173	Lepisosteus oculatus	82.76	0.00e+00	1015.00
IUUC-Laf-054017	Loxodonta africana	96.03	0.00e+00	1122.00
IUUC-Mcc-055713	Macaca mulatta	95.86	0.00e+00	1120.00
IUUC-Meu-056212	Macropus eugenii	69.44	8.00e-115	407.00
IUUC-Mor-057045	Magnaporthe oryzae	36.02	1.00e-86	315.00
IUUC-Mla-059187	Melampsora laricipopulina	43.74	9.00e-87	313.00
IUUC-Mga-059884	Meleagris gallopavo	79.73	0.00e+00	916.00
IUUC-Mmr-061344	Microcebus murinus	97.59	0.00e+00	1162.00
IUUC-Mdo-062653	Monodelphis domestica	92.76	0.00e+00	1092.00
IUUC-Mmu-063775	Mus musculus	94.32	0.00e+00	1078.00
IUUC-Mpu-066069	Mustela putorius furo	96.90	0.00e+00	1152.00
IUUC-Mlu-067925	Myotis lucifugus	96.38	0.00e+00	1125.00
IUUC-Nfi-068439	Neosartorya fischeri	33.93	4.00e-89	323.00
IUUC-Ncr-068903	Neurospora crassa	37.68	2.00e-90	328.00
IUUC-Nle-070046	Nomascus leucogenys	95.34	0.00e+00	1145.00
IUUC-Opr-071085	Ochotona princeps	78.86	8.00e-135	474.00
IUUC-Ont-072126	Oreochromis niloticus	78.10	0.00e+00	965.00
IUUC-Oan-072933	Ornithorhynchus anatinus	88.97	0.00e+00	1038.00
IUUC-Ocu-073800	Oryctolagus cuniculus	97.07	0.00e+00	1128.00
IUUC-Ola-086988	Oryzias latipes	77.80	0.00e+00	952.00
IUUC-Oar-089371	Ovis aries	96.90	0.00e+00	1129.00
IUUC-Ptr-090551	Pan troglodytes	95.17	0.00e+00	1116.00
IUUC-Pan-092067	Papio anubis	95.86	0.00e+00	1113.00
IUUC-Psi-092963	Pelodiscus sinensis	89.14	0.00e+00	1049.00
IUUC-Pfo-096562	Poecilia formosa	76.55	0.00e+00	945.00
IUUC-Pab-098680	Pongo abelii	95.52	0.00e+00	1113.00
IUUC-Pca-100986	Procavia capensis	73.70	0.00e+00	766.00
IUUC-Pva-102219	Pteropus vampyrus	83.15	0.00e+00	891.00
IUUC-Pgr-103315	Puccinia graminis	37.23	5.00e-92	332.00
IUUC-Ptt-103736	Puccinia triticina	42.13	2.00e-94	340.00
IUUC-Rno-105270	Rattus norvegicus	94.48	0.00e+00	1079.00
IUUC-Sce-106306	Saccharomyces cerevisiae	34.84	3.00e-69	256.00
IUUC-Sha-106819	Sarcophilus harrisii	93.12	0.00e+00	1110.00
IUUC-Spo-108271	Schizosaccharomyces pombe	34.30	2.00e-82	300.00
IUUC-Ssl-108657	Sclerotinia sclerotiorum	36.54	7.00e-81	295.00
IUUC-Sar-113134	Sorex araneus	86.03	0.00e+00	985.00
IUUC-Ssc-115441	Sus scrofa	96.56	0.00e+00	1126.00
IUUC-Tgu-117166	Taeniopygia guttata	87.41	0.00e+00	1027.00
IUUC-Tsy-118898	Tarsius syrichta	86.45	0.00e+00	944.00
IUUC-Tre-122108	Trichoderma reesei	39.03	1.00e-87	318.00
IUUC-Tvi-122644	Trichoderma virens	39.31	4.00e-93	336.00
IUUC-Tme-127004	Tuber melanosporum	34.50	2.00e-98	355.00
IUUC-Tbe-127292	Tupaia belangeri	75.00	0.00e+00	803.00
IUUC-Ttr-128352	Tursiops truncatus	91.55	0.00e+00	1047.00
IUUC-Vda-129969	Verticillium dahliae	39.78	8.00e-90	325.00
IUUC-Vpa-130218	Vicugna pacos	93.83	0.00e+00	743.00
IUUC-Xtr-132594	Xenopus tropicalis	81.69	0.00e+00	926.00
IUUC-Xma-134157	Xiphophorus maculatus	76.16	0.00e+00	872.00
IUUC-Yli-134470	Yarrowia lipolytica	34.95	2.00e-74	273.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence