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Tag Content
UUCD2 ID IUUC-Aml-002245
UUCD1 version UUC-AiM-00689
Ensembl Protein ID ENSAMEP00000013286.1
UniProt Accession G1M1S5; G1M1S5_AILME
Genbank Protein ID ENSAMEP00000013286
Protein Name Uncharacterized protein
Genbank Nucleotide ID ACTA01073331
Gene Name WDR61
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSAMEG00000012599.1 ENSAMET00000013843.1 ENSAMEP00000013286.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 3.00e-44 147.1 230 269
UBD/Beta-Prp 8.10e-75 251.8 12 303
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH+++v  +af +d t++vs+s D+++kvWD+ t +++++
   Q: 230  GHASWVLNVAFcPDdTHFVSSSSDKSVKVWDVGTRTCVHT 269
           8***********777*****************99999875 PP
   

   UBD/Beta-Prp
   S: 6    kghhksvitcvkf....spdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvh 88
           +++h++ i +v++    +++++ ++tgs d+ +kvw+++++ l   +sl+gh+ +v +v++s++ +i +++s D++i++wdl++gk++ 
   Q: 12   EQAHDDAIWSVAWgtnkKENSETVVTGSLDDLVKVWKWSDERLdlQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRLWDLENGKQIK 100
           567788888899998888999********************99999******************************************* PP
   S: 89   tlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltg 177
           ++ +   ++++l+fsp++++l++G+h+  ++++ +e+g++ +  l+ + +++ +++++pdg++l+sG+ D++++++d++tgkll+tl+g
   Q: 101  SIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEY-SLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEG 188
           ******************************************.*********************************************9 PP
   S: 178  ghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnss 266
            h  +++sl+f+++++ lv++s+dg++k++d+q+ +   tl gh ++v+ v+f+p+d+++vs ssD+s+++Wd+ ++++++t+  h+++
   Q: 189  -HAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQ 276
           .**************************************************************************************** PP
   S: 267  visvavlsfgdnvlvlgsedskvniwkl 294
           v+ v++ + +++++v++++d++++++++
   Q: 277  VWGVKY-NGNGSKIVSVGDDQEIHVYDC 303
           ******.999****************97 PP
   
Organism Ailuropoda melanoleuca
Protein Sequence
(Fasta)
MTNQYSILFK QEQAHDDAIW SVAWGTNKKE NSETVVTGSL DDLVKVWKWS DERLDLQWSL 60
EGHQLGVVSV DISHTLPIAA SSSLDAHIRL WDLENGKQIK SIDAGPVDAW TLAFSPDSQY 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Aml-002245|E3,WD_repeat;UBD,Beta-Prp|Ailuropoda melanoleuca
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGACCAACC AGGTAAGGCC TGTGGTGACG GGAAGAACAG CAGTTGGTCT CTTTGGCAGG 60
TTGAAGGCCA GTATGTGGTC TGGGTGTGTA GTCAGGAGAC TAGCATCTGA TTCCTGCTCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Aml-002245|E3,WD_repeat;UBD,Beta-Prp|Ailuropoda melanoleuca
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat
Interpro

IPR003143--Cyt_cd1_C
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0016593--C:Cdc73/Paf1 complex
GO:0005829--C:cytosol
GO:0055087--C:Ski complex
GO:0035327--C:transcriptionally active chromatin
GO:0080182--P:histone H3-K4 trimethylation
GO:0045638--P:negative regulation of myeloid cell differentiation
GO:0051571--P:positive regulation of histone H3-K4 methylation
GO:2001162--P:positive regulation of histone H3-K79 methylation
GO:0032968--P:positive regulation of transcription elongation from RNA polymerase II promoter
KEGG aml:100480255
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000774 Aegilops tauschii 33.93 1.00e-47 183.00
IUUC-Atr-003142 Amborella trichopoda 51.55 2.00e-38 151.00
IUUC-Apl-003179 Anas platyrhynchos 90.82 4.00e-157 546.00
IUUC-Aca-004880 Anolis carolinensis 89.18 4.00e-158 550.00
IUUC-Aly-005956 Arabidopsis lyrata 37.50 3.00e-55 208.00
IUUC-Ath-007230 Arabidopsis thaliana 37.18 4.00e-51 194.00
IUUC-Acl-008297 Aspergillus clavatus 28.88 4.00e-25 108.00
IUUC-Ang-009702 Aspergillus niger 29.90 4.00e-30 125.00
IUUC-Ame-011511 Astyanax mexicanus 84.04 9.00e-150 522.00
IUUC-Bgr-012189 Blumeria graminis 30.47 8.00e-29 120.00
IUUC-Bta-012936 Bos taurus 98.36 6.00e-168 582.00
IUUC-Bdi-015020 Brachypodium distachyon 37.59 3.00e-47 182.00
IUUC-Bol-016345 Brassica oleracea 38.78 2.00e-56 212.00
IUUC-Bra-017323 Brassica rapa 38.78 1.00e-56 213.00
IUUC-Cja-019961 Callithrix jacchus 98.69 4.00e-168 583.00
IUUC-Cfa-020862 Canis familiaris 99.34 2.00e-168 584.00
IUUC-Cpo-021356 Cavia porcellus 99.01 1.00e-166 578.00
IUUC-Cre-022602 Chlamydomonas reinhardtii 41.91 5.00e-58 217.00
IUUC-Csa-024067 Chlorocebus sabaeus 98.36 2.00e-167 581.00
IUUC-Cho-024421 Choloepus hoffmanni 82.83 2.00e-82 298.00
IUUC-Cin-025261 Ciona intestinalis 64.26 3.00e-116 411.00
IUUC-Cgl-026446 Colletotrichum gloeosporioides 28.30 4.00e-29 121.00
IUUC-Cne-026846 Cryptococcus neoformans 29.13 9.00e-25 107.00
IUUC-Dre-027706 Danio rerio 65.90 1.00e-110 392.00
IUUC-Dno-029084 Dasypus novemcinctus 98.37 4.00e-167 580.00
IUUC-Dor-030353 Dipodomys ordii 83.33 9.00e-124 436.00
IUUC-Dse-031348 Dothistroma septosporum 31.03 4.00e-26 111.00
IUUC-Dme-031836 Drosophila melanogaster 52.31 5.00e-88 317.00
IUUC-Ete-032261 Echinops telfairi 95.41 2.00e-161 561.00
IUUC-Eca-034231 Equus caballus 90.82 1.00e-152 532.00
IUUC-Eeu-034828 Erinaceus europaeus 98.28 5.00e-157 546.00
IUUC-Fca-036569 Felis catus 99.34 7.00e-169 585.00
IUUC-Fal-037469 Ficedula albicollis 92.79 6.00e-161 559.00
IUUC-Fox-038047 Fusarium oxysporum 33.00 2.00e-29 122.00
IUUC-Gmo-039579 Gadus morhua 83.93 1.00e-146 512.00
IUUC-Gga-040808 Gallus gallus 93.49 3.00e-154 537.00
IUUC-Gac-042100 Gasterosteus aculeatus 84.26 8.00e-148 515.00
IUUC-Gma-044408 Glycine max 41.35 2.00e-59 222.00
IUUC-Ggo-045227 Gorilla gorilla 98.69 4.00e-168 583.00
IUUC-Hsa-045839 Homo sapiens 98.69 4.00e-168 583.00
IUUC-Hvu-047591 Hordeum vulgare 37.97 1.00e-49 190.00
IUUC-Itr-048741 Ictidomys tridecemlineatus 99.02 9.00e-169 585.00
IUUC-Lch-049549 Latimeria chalumnae 83.93 8.00e-148 515.00
IUUC-Lpe-050746 Leersia perrieri 38.59 3.00e-48 185.00
IUUC-Loc-052540 Lepisosteus oculatus 87.21 1.00e-149 521.00
IUUC-Lma-052992 Leptosphaeria maculans 28.14 1.00e-27 116.00
IUUC-Laf-053907 Loxodonta africana 99.02 9.00e-169 585.00
IUUC-Mcc-055828 Macaca mulatta 92.31 5.00e-164 569.00
IUUC-Meu-056075 Macropus eugenii 94.49 6.00e-135 473.00
IUUC-Mtr-057728 Medicago truncatula 40.71 2.00e-56 212.00
IUUC-Mga-059872 Meleagris gallopavo 93.11 2.00e-161 561.00
IUUC-Mvi-060564 Microbotryum violaceum 32.44 3.00e-30 125.00
IUUC-Mmr-060985 Microcebus murinus 98.63 3.00e-160 557.00
IUUC-Mdo-062758 Monodelphis domestica 90.46 8.00e-159 552.00
IUUC-Mmu-063580 Mus musculus 97.38 2.00e-166 577.00
IUUC-Mac-064880 Musa acuminata 40.19 6.00e-58 217.00
IUUC-Mpu-066577 Mustela putorius furo 99.34 5.00e-168 583.00
IUUC-Nle-069573 Nomascus leucogenys 98.69 4.00e-168 583.00
IUUC-Opr-070216 Ochotona princeps 98.67 3.00e-165 573.00
IUUC-Ont-071981 Oreochromis niloticus 85.57 8.00e-151 526.00
IUUC-Oan-073223 Ornithorhynchus anatinus 93.94 8.00e-108 382.00
IUUC-Ocu-074199 Oryctolagus cuniculus 85.25 2.00e-140 491.00
IUUC-Oba-075255 Oryza barthii 40.00 1.00e-41 162.00
IUUC-Obr-076168 Oryza brachyantha 47.20 1.00e-35 143.00
IUUC-Ogl-077777 Oryza glaberrima 38.39 9.00e-49 187.00
IUUC-Ogu-078780 Oryza glumaepatula 38.39 9.00e-49 187.00
IUUC-Oin-079228 Oryza indica 38.39 2.00e-51 196.00
IUUC-Olo-080617 Oryza longistaminata 45.77 3.00e-29 120.00
IUUC-Ome-081421 Oryza meridionalis 38.39 6.00e-48 184.00
IUUC-Oni-082997 Oryza nivara 38.39 2.00e-51 196.00
IUUC-Opu-083931 Oryza punctata 38.71 7.00e-49 187.00
IUUC-Oru-084645 Oryza rufipogon 38.39 9.00e-49 187.00
IUUC-Osa-085842 Oryza sativa 38.39 2.00e-51 196.00
IUUC-Ola-086696 Oryzias latipes 85.25 1.00e-146 511.00
IUUC-Olu-087643 Ostreococcus lucimarinus 39.91 1.00e-41 162.00
IUUC-Oga-088272 Otolemur garnettii 97.37 4.00e-165 573.00
IUUC-Oar-089416 Ovis aries 98.36 6.00e-168 582.00
IUUC-Ptr-090944 Pan troglodytes 98.69 4.00e-168 583.00
IUUC-Pan-091861 Papio anubis 98.69 4.00e-168 583.00
IUUC-Psi-093750 Pelodiscus sinensis 93.44 7.00e-162 562.00
IUUC-Pma-094608 Petromyzon marinus 79.68 1.00e-135 475.00
IUUC-Pno-094832 Phaeosphaeria nodorum 32.59 3.00e-26 112.00
IUUC-Ppa-095737 Physcomitrella patens 40.06 4.00e-56 211.00
IUUC-Pfo-096479 Poecilia formosa 86.23 9.00e-145 505.00
IUUC-Pab-098179 Pongo abelii 98.69 4.00e-168 583.00
IUUC-Pop-099532 Populus trichocarpa 40.91 3.00e-56 211.00
IUUC-Pca-100664 Procavia capensis 76.45 2.00e-105 375.00
IUUC-Ppe-102056 Prunus persica 40.26 4.00e-58 218.00
IUUC-Pva-102859 Pteropus vampyrus 99.02 5.00e-168 583.00
IUUC-Pte-104236 Pyrenophora teres 35.56 2.00e-25 109.00
IUUC-Rno-105826 Rattus norvegicus 97.05 8.00e-166 575.00
IUUC-Sha-106660 Sarcophilus harrisii 92.03 6.00e-153 533.00
IUUC-Sja-107800 Schizosaccharomyces japonicus 33.22 2.00e-36 145.00
IUUC-Spo-108244 Schizosaccharomyces pombe 31.39 2.00e-35 142.00
IUUC-Smo-109234 Selaginella moellendorffii 42.81 4.00e-61 228.00
IUUC-Sit-110048 Setaria italica 36.86 1.00e-40 160.00
IUUC-Sly-111618 Solanum lycopersicum 38.78 2.00e-52 199.00
IUUC-Stu-112543 Solanum tuberosum 39.10 2.00e-55 209.00
IUUC-Sar-113743 Sorex araneus 78.03 3.00e-130 457.00
IUUC-Sbi-114309 Sorghum bicolor 38.57 7.00e-42 164.00
IUUC-Ssc-115560 Sus scrofa 92.79 8.00e-155 539.00
IUUC-Tgu-117300 Taeniopygia guttata 93.11 2.00e-161 561.00
IUUC-Tru-117933 Takifugu rubripes 84.92 6.00e-150 523.00
IUUC-Tsy-119574 Tarsius syrichta 88.20 7.00e-145 506.00
IUUC-Tni-120191 Tetraodon nigroviridis 86.92 7.00e-113 399.00
IUUC-Tca-120983 Theobroma cacao 39.81 7.00e-57 214.00
IUUC-Tae-124056 Triticum aestivum 36.16 1.00e-49 189.00
IUUC-Tur-126711 Triticum urartu 36.05 1.00e-48 186.00
IUUC-Tme-127066 Tuber melanosporum 33.83 7.00e-34 137.00
IUUC-Tbe-127802 Tupaia belangeri 99.34 7.00e-169 585.00
IUUC-Ttr-128861 Tursiops truncatus 98.11 3.00e-56 211.00
IUUC-Vda-129720 Verticillium dahliae 29.27 8.00e-23 100.00
IUUC-Vpa-130618 Vicugna pacos 95.14 3.00e-135 473.00
IUUC-Vvi-130981 Vitis vinifera 40.38 9.00e-56 210.00
IUUC-Xtr-132460 Xenopus tropicalis 86.56 5.00e-147 513.00
IUUC-Xma-134154 Xiphophorus maculatus 86.23 6.00e-145 506.00
IUUC-Yli-134554 Yarrowia lipolytica 27.90 3.00e-20 92.40
Created Date 25-Jun-2017

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