iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062758

UUCD1 version

UUC-MoD-00960

Ensembl Protein ID

ENSMODP00000014657.2

UniProt Accession

F7G3R0; F7G3R0_MONDO

Protein Name

Uncharacterized protein

Gene Name

WDR61

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000011702.2	ENSMODT00000014928.2	ENSMODP00000014657.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.50e-43	143.9	15	54
UBD/Beta-Prp	1.30e-73	248.0	12	303

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.....sd.tllvsGsdDgtikvWDlrtgvl 35
           H d ++++a+     ++  ++vsGs D  +kvW+++ ++l
   Q: 15   HDDAIWSVAWgtnqrDNsEMIVSGSLDDLVKVWRWKNDKL 54
           99************8446****************998876 PP

UBD/Beta-Prp

   S: 6    kghhksvitcvkf....spdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvh 88
           +++h++ i +v++     ++++++++gs d+ +kvw++++ kl   +sl+gh+ +v +v++s++g i +++s D++i++wdl++gk++ 
   Q: 12   EQAHDDAIWSVAWgtnqRDNSEMIVSGSLDDLVKVWRWKNDKLelQWSLEGHQLGVVSVDISHTGTIAASSSLDAHIRLWDLENGKQMK 100
           567777888899988878899********************999899****************************************** PP
   S: 89   tlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltg 177
           ++ +   +++sl+fsp++++l++Gsh   ++++ +etg++ +  l+ + +++ +++++pdg++l+sG+ D++++++d+++gkll+tl+g
   Q: 101  AIDAGPVDAWSLAFSPDSQFLATGSHIGKVNIFGVETGKKEY-SLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIASGKLLHTLEG 188
           ******************************************.*********************************************9 PP
   S: 178  ghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnss 266
            h  +++sl+f+++++ lv++s+dg++k++d+q+ +   tl gh ++v+ v+f+p+d ++vs ssD+s+++Wd  ++++++t+  h+++
   Q: 189  -HAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDIHFVSSSSDKSVKVWDAGTRTCVHTFFDHQDQ 276
           .**************************************************************************************** PP
   S: 267  visvavlsfgdnvlvlgsedskvniwkl 294
           v+ v++ + +++++v++++d++++i+++
   Q: 277  VWGVKY-NGTGSKVVSVGDDQEIHIYDC 303
           ******.999****************97 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MSVQYSILFK QEQAHDDAIW SVAWGTNQRD NSEMIVSGSL DDLVKVWRWK NDKLELQWSL 60
EGHQLGVVSV DISHTGTIAA SSSLDAHIRL WDLENGKQMK AIDAGPVDAW SLAFSPDSQF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGGGGCGC CCGGAGTCCT CAGAGACGCG TGGAGCGCAC GCGGCGTCGT GACGTCATCC 60
CAGCCCGCCG CCCTCAGCTC GCGCGTCATA ACCCAGCGCC TCTGTCGCTA AGGAAGAAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016593--C:Cdc73/Paf1 complex
GO:0005829--C:cytosol
GO:0055087--C:Ski complex
GO:0035327--C:transcriptionally active chromatin
GO:0080182--P:histone H3-K4 trimethylation
GO:0045638--P:negative regulation of myeloid cell differentiation
GO:0051571--P:positive regulation of histone H3-K4 methylation
GO:2001162--P:positive regulation of histone H3-K79 methylation
GO:0032968--P:positive regulation of transcription elongation from RNA polymerase II promoter

KEGG

mdo:100026110

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000774	Aegilops tauschii	34.33	2.00e-47	182.00
IUUC-Aml-002245	Ailuropoda melanoleuca	90.46	7.00e-157	546.00
IUUC-Atr-003142	Amborella trichopoda	53.42	1.00e-38	152.00
IUUC-Apl-003179	Anas platyrhynchos	89.47	2.00e-156	544.00
IUUC-Aca-004880	Anolis carolinensis	87.83	1.00e-155	541.00
IUUC-Aly-005956	Arabidopsis lyrata	38.98	2.00e-57	215.00
IUUC-Ath-007230	Arabidopsis thaliana	37.82	9.00e-52	197.00
IUUC-Acl-008297	Aspergillus clavatus	30.77	9.00e-26	111.00
IUUC-Ame-011511	Astyanax mexicanus	83.33	1.00e-148	518.00
IUUC-Bgr-012189	Blumeria graminis	31.18	5.00e-29	121.00
IUUC-Bta-012936	Bos taurus	90.79	4.00e-157	546.00
IUUC-Bdi-015020	Brachypodium distachyon	38.23	3.00e-47	182.00
IUUC-Bol-015927	Brassica oleracea	38.46	8.00e-58	217.00
IUUC-Bra-017323	Brassica rapa	38.98	8.00e-58	217.00
IUUC-Cja-019961	Callithrix jacchus	90.46	9.00e-157	545.00
IUUC-Cfa-020862	Canis familiaris	90.13	6.00e-156	543.00
IUUC-Cpo-021356	Cavia porcellus	91.03	1.00e-155	542.00
IUUC-Cre-022602	Chlamydomonas reinhardtii	41.72	4.00e-56	211.00
IUUC-Csa-024067	Chlorocebus sabaeus	90.13	3.00e-156	543.00
IUUC-Cho-024421	Choloepus hoffmanni	79.19	2.00e-79	287.00
IUUC-Cin-025261	Ciona intestinalis	64.80	2.00e-116	412.00
IUUC-Cgl-026446	Colletotrichum gloeosporioides	27.99	6.00e-28	117.00
IUUC-Cne-026846	Cryptococcus neoformans	28.39	3.00e-23	102.00
IUUC-Dre-027706	Danio rerio	64.47	7.00e-109	386.00
IUUC-Dno-029084	Dasypus novemcinctus	90.20	7.00e-156	542.00
IUUC-Dor-030353	Dipodomys ordii	75.72	5.00e-115	406.00
IUUC-Dse-031348	Dothistroma septosporum	29.31	6.00e-25	108.00
IUUC-Dme-031836	Drosophila melanogaster	51.84	8.00e-90	323.00
IUUC-Ete-032261	Echinops telfairi	88.82	2.00e-151	528.00
IUUC-Eca-034231	Equus caballus	82.89	6.00e-142	496.00
IUUC-Eeu-034828	Erinaceus europaeus	90.00	3.00e-147	513.00
IUUC-Fca-036569	Felis catus	90.79	1.00e-156	545.00
IUUC-Fal-037469	Ficedula albicollis	90.79	2.00e-158	551.00
IUUC-Fox-038047	Fusarium oxysporum	31.99	5.00e-28	118.00
IUUC-Gmo-039579	Gadus morhua	83.88	9.00e-146	509.00
IUUC-Gga-040808	Gallus gallus	92.10	5.00e-153	533.00
IUUC-Gac-042100	Gasterosteus aculeatus	83.88	3.00e-146	511.00
IUUC-Gma-043509	Glycine max	40.50	3.00e-61	228.00
IUUC-Ggo-045227	Gorilla gorilla	90.46	9.00e-157	545.00
IUUC-Hsa-045839	Homo sapiens	90.46	9.00e-157	545.00
IUUC-Hvu-047591	Hordeum vulgare	38.49	2.00e-49	189.00
IUUC-Itr-048741	Ictidomys tridecemlineatus	90.79	2.00e-157	547.00
IUUC-Lch-049549	Latimeria chalumnae	82.57	2.00e-145	508.00
IUUC-Lpe-050746	Leersia perrieri	38.91	5.00e-48	184.00
IUUC-Loc-052540	Lepisosteus oculatus	86.18	1.00e-147	515.00
IUUC-Lma-052992	Leptosphaeria maculans	29.83	4.00e-28	118.00
IUUC-Laf-053907	Loxodonta africana	90.79	2.00e-157	547.00
IUUC-Mcc-055828	Macaca mulatta	84.57	1.00e-152	531.00
IUUC-Meu-056075	Macropus eugenii	96.86	1.00e-138	485.00
IUUC-Mor-056971	Magnaporthe oryzae	32.29	3.00e-24	105.00
IUUC-Mtr-057728	Medicago truncatula	40.71	5.00e-58	217.00
IUUC-Mga-059872	Meleagris gallopavo	91.45	7.00e-160	556.00
IUUC-Mvi-060564	Microbotryum violaceum	31.88	1.00e-30	127.00
IUUC-Mmr-060985	Microcebus murinus	91.41	8.00e-151	526.00
IUUC-Mmu-063580	Mus musculus	90.13	1.00e-156	545.00
IUUC-Mac-064880	Musa acuminata	40.51	4.00e-58	218.00
IUUC-Mpu-066577	Mustela putorius furo	89.80	4.00e-155	540.00
IUUC-Nle-069573	Nomascus leucogenys	90.46	9.00e-157	545.00
IUUC-Opr-070216	Ochotona princeps	90.67	9.00e-155	538.00
IUUC-Ont-071981	Oreochromis niloticus	84.54	4.00e-149	520.00
IUUC-Oan-073223	Ornithorhynchus anatinus	94.44	2.00e-108	384.00
IUUC-Ocu-074199	Oryctolagus cuniculus	77.38	4.00e-129	453.00
IUUC-Oba-075255	Oryza barthii	41.15	3.00e-41	162.00
IUUC-Obr-076168	Oryza brachyantha	48.45	2.00e-35	142.00
IUUC-Ogl-077777	Oryza glaberrima	38.71	1.00e-48	186.00
IUUC-Ogu-078780	Oryza glumaepatula	38.71	1.00e-48	186.00
IUUC-Oin-079228	Oryza indica	38.91	4.00e-51	194.00
IUUC-Olo-080617	Oryza longistaminata	47.18	3.00e-29	120.00
IUUC-Ome-081421	Oryza meridionalis	38.91	9.00e-48	183.00
IUUC-Oni-082997	Oryza nivara	38.91	4.00e-51	194.00
IUUC-Opu-083931	Oryza punctata	39.23	9.00e-49	187.00
IUUC-Oru-084645	Oryza rufipogon	38.71	1.00e-48	186.00
IUUC-Osa-085842	Oryza sativa	38.91	4.00e-51	194.00
IUUC-Ola-086696	Oryzias latipes	84.54	1.00e-144	505.00
IUUC-Olu-087643	Ostreococcus lucimarinus	38.97	2.00e-40	158.00
IUUC-Oga-088272	Otolemur garnettii	90.13	2.00e-155	541.00
IUUC-Oar-089416	Ovis aries	90.79	4.00e-157	546.00
IUUC-Ptr-090944	Pan troglodytes	90.46	9.00e-157	545.00
IUUC-Pan-091861	Papio anubis	90.46	9.00e-157	545.00
IUUC-Psi-093750	Pelodiscus sinensis	91.45	5.00e-159	553.00
IUUC-Pma-094608	Petromyzon marinus	79.94	8.00e-136	476.00
IUUC-Pno-094832	Phaeosphaeria nodorum	29.93	1.00e-25	110.00
IUUC-Ppa-095737	Physcomitrella patens	40.06	7.00e-58	217.00
IUUC-Pfo-096479	Poecilia formosa	84.87	1.00e-141	495.00
IUUC-Pab-098179	Pongo abelii	90.46	9.00e-157	545.00
IUUC-Pop-099532	Populus trichocarpa	40.91	3.00e-57	215.00
IUUC-Pca-100664	Procavia capensis	70.65	1.00e-98	352.00
IUUC-Ppe-102056	Prunus persica	39.61	2.00e-58	219.00
IUUC-Pva-102859	Pteropus vampyrus	90.46	4.00e-156	543.00
IUUC-Pte-104236	Pyrenophora teres	30.41	2.00e-24	106.00
IUUC-Rno-105826	Rattus norvegicus	90.13	6.00e-156	543.00
IUUC-Sha-106660	Sarcophilus harrisii	95.68	5.00e-158	550.00
IUUC-Sja-107800	Schizosaccharomyces japonicus	33.55	2.00e-36	145.00
IUUC-Spo-108244	Schizosaccharomyces pombe	30.42	1.00e-32	133.00
IUUC-Smo-109382	Selaginella moellendorffii	43.14	1.00e-62	233.00
IUUC-Sit-110048	Setaria italica	37.46	8.00e-41	160.00
IUUC-Sly-111618	Solanum lycopersicum	38.46	8.00e-52	197.00
IUUC-Stu-112543	Solanum tuberosum	37.82	1.00e-54	206.00
IUUC-Sar-113743	Sorex araneus	71.05	7.00e-120	423.00
IUUC-Sbi-114309	Sorghum bicolor	38.83	1.00e-41	163.00
IUUC-Ssc-115560	Sus scrofa	85.86	4.00e-146	509.00
IUUC-Tgu-117300	Taeniopygia guttata	91.12	5.00e-159	553.00
IUUC-Tru-117933	Takifugu rubripes	84.21	9.00e-148	515.00
IUUC-Tsy-119574	Tarsius syrichta	79.93	3.00e-133	467.00
IUUC-Tni-120191	Tetraodon nigroviridis	86.44	1.00e-111	395.00
IUUC-Tca-120983	Theobroma cacao	40.13	2.00e-59	222.00
IUUC-Tae-122888	Triticum aestivum	36.68	2.00e-49	189.00
IUUC-Tur-126711	Triticum urartu	36.56	3.00e-48	185.00
IUUC-Tme-127066	Tuber melanosporum	33.46	6.00e-34	138.00
IUUC-Tbe-127802	Tupaia belangeri	90.79	1.00e-156	545.00
IUUC-Ttr-128861	Tursiops truncatus	89.60	2.00e-51	196.00
IUUC-Vda-129720	Verticillium dahliae	32.48	5.00e-23	101.00
IUUC-Vpa-130618	Vicugna pacos	86.23	2.00e-125	441.00
IUUC-Vvi-130981	Vitis vinifera	40.71	1.00e-57	216.00
IUUC-Xtr-132460	Xenopus tropicalis	85.20	5.00e-146	509.00
IUUC-Xma-134154	Xiphophorus maculatus	84.87	7.00e-142	496.00
IUUC-Yli-134554	Yarrowia lipolytica	29.15	6.00e-22	97.80

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence