iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054535

UUCD1 version

UUC-LoA-00170

Ensembl Protein ID

ENSLAFP00000004022.2

UniProt Accession

G3SUZ5; G3SUZ5_LOXAF

Protein Name

Uncharacterized protein

Gene Name

WDR77

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000004805.2	ENSLAFT00000004805.2	ENSLAFP00000004022.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.60e-17	62.2	166	201

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf...sdtllvsGsdDgtikvWDlrtgv 34
           H++ vtc+a     d +++s+s D  i +WD+r+ +
   Q: 166  HSGQVTCVAAsphKDSMFLSCSEDSRILLWDTRCPK 201
           9*******988765599**************99876 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MRKETPPPLV PSAAREWNLP ANAPACMERQ LEAARYRSDG ALLLGASSLS GRCWAGSLWL 60
FKDPCSAPNE GFCSAGVQTE AGVADLTWVG DKGILVASDS GAVELWELDE NETLIVSKFC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCGGAAGG AAACCCCACC TCCGTTGGTG CCCTCGGCGG CCCGCGAGTG GAACCTCCCC 60
GCTAATGCGC CCGCCTGTAT GGAGCGGCAG TTGGAGGCTG CGCGGTACCG GTCCGGTGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0034709--C:methylosome
GO:0005654--C:nucleoplasm
GO:0030374--F:ligand-dependent nuclear receptor transcription coactivator activity
GO:0008327--F:methyl-CpG binding
GO:0060770--P:negative regulation of epithelial cell proliferation involved in prostate gland development
GO:0008284--P:positive regulation of cell proliferation
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0060528--P:secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002192	Ailuropoda melanoleuca	89.97	1.00e-176	612.00
IUUC-Apl-003921	Anas platyrhynchos	64.74	3.00e-69	253.00
IUUC-Aca-004870	Anolis carolinensis	68.03	2.00e-119	422.00
IUUC-Ame-011872	Astyanax mexicanus	46.28	6.00e-36	143.00
IUUC-Bta-013325	Bos taurus	90.23	2.00e-178	617.00
IUUC-Cja-019059	Callithrix jacchus	89.66	8.00e-177	612.00
IUUC-Cfa-021036	Canis familiaris	89.56	3.00e-155	541.00
IUUC-Cpo-022369	Cavia porcellus	90.23	1.00e-177	615.00
IUUC-Csa-023585	Chlorocebus sabaeus	89.66	2.00e-177	614.00
IUUC-Cho-024470	Choloepus hoffmanni	85.02	2.00e-118	417.00
IUUC-Dno-029867	Dasypus novemcinctus	88.79	4.00e-178	616.00
IUUC-Dor-030834	Dipodomys ordii	62.64	7.00e-112	396.00
IUUC-Ete-032245	Echinops telfairi	85.86	6.00e-145	506.00
IUUC-Eca-033360	Equus caballus	89.66	3.00e-170	590.00
IUUC-Eeu-035353	Erinaceus europaeus	87.93	1.00e-172	598.00
IUUC-Fca-036277	Felis catus	91.38	6.00e-180	622.00
IUUC-Fal-037383	Ficedula albicollis	66.42	2.00e-101	361.00
IUUC-Gmo-038575	Gadus morhua	53.69	1.00e-97	349.00
IUUC-Gga-040658	Gallus gallus	69.28	4.00e-128	450.00
IUUC-Gac-041463	Gasterosteus aculeatus	52.23	4.00e-84	304.00
IUUC-Ggo-045120	Gorilla gorilla	88.22	6.00e-175	606.00
IUUC-Hsa-046247	Homo sapiens	88.79	7.00e-176	609.00
IUUC-Itr-048292	Ictidomys tridecemlineatus	89.94	7.00e-173	599.00
IUUC-Lch-049741	Latimeria chalumnae	64.80	8.00e-112	396.00
IUUC-Loc-052695	Lepisosteus oculatus	57.64	1.00e-104	372.00
IUUC-Mcc-054699	Macaca mulatta	89.66	2.00e-177	614.00
IUUC-Meu-056053	Macropus eugenii	75.29	3.00e-137	481.00
IUUC-Mga-059672	Meleagris gallopavo	64.50	6.00e-71	259.00
IUUC-Mmr-060963	Microcebus murinus	91.38	0.00e+00	627.00
IUUC-Mdo-062694	Monodelphis domestica	72.75	8.00e-131	459.00
IUUC-Mmu-064031	Mus musculus	87.36	5.00e-173	600.00
IUUC-Mpu-066408	Mustela putorius furo	90.80	3.00e-179	620.00
IUUC-Mlu-068184	Myotis lucifugus	88.83	3.00e-174	603.00
IUUC-Nle-069251	Nomascus leucogenys	89.94	5.00e-178	616.00
IUUC-Opr-071156	Ochotona princeps	82.76	2.00e-161	561.00
IUUC-Ont-072683	Oreochromis niloticus	55.66	5.00e-94	337.00
IUUC-Oan-073042	Ornithorhynchus anatinus	73.58	2.00e-126	445.00
IUUC-Ocu-074843	Oryctolagus cuniculus	90.26	8.00e-173	599.00
IUUC-Ola-086929	Oryzias latipes	53.19	1.00e-87	316.00
IUUC-Oga-088237	Otolemur garnettii	89.08	6.00e-176	609.00
IUUC-Oar-089312	Ovis aries	90.37	1.00e-163	568.00
IUUC-Ptr-091625	Pan troglodytes	88.51	2.00e-175	607.00
IUUC-Pan-091902	Papio anubis	85.96	1.00e-167	581.00
IUUC-Psi-094035	Pelodiscus sinensis	73.22	3.00e-130	457.00
IUUC-Pma-094565	Petromyzon marinus	64.09	1.00e-57	215.00
IUUC-Pfo-097070	Poecilia formosa	54.09	2.00e-91	328.00
IUUC-Pab-098007	Pongo abelii	89.08	2.00e-176	611.00
IUUC-Pca-100513	Procavia capensis	76.47	2.00e-107	381.00
IUUC-Pva-102821	Pteropus vampyrus	85.63	5.00e-164	569.00
IUUC-Rno-105836	Rattus norvegicus	89.66	0.00e+00	626.00
IUUC-Sha-106847	Sarcophilus harrisii	69.44	1.00e-88	319.00
IUUC-Sar-113451	Sorex araneus	83.38	3.00e-166	577.00
IUUC-Ssc-115978	Sus scrofa	89.08	4.00e-170	590.00
IUUC-Tgu-116745	Taeniopygia guttata	68.94	1.00e-94	338.00
IUUC-Tru-117945	Takifugu rubripes	55.00	2.00e-83	302.00
IUUC-Tsy-119059	Tarsius syrichta	83.61	2.00e-86	310.00
IUUC-Tni-120414	Tetraodon nigroviridis	54.71	2.00e-94	338.00
IUUC-Tbe-127559	Tupaia belangeri	92.53	0.00e+00	632.00
IUUC-Ttr-128505	Tursiops truncatus	88.51	1.00e-172	598.00
IUUC-Vpa-130350	Vicugna pacos	90.96	1.00e-99	354.00
IUUC-Xtr-132939	Xenopus tropicalis	60.06	9.00e-110	389.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence