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Tag Content
iUUCD ID IUUC-Tru-118410
Ensembl Protein ID ENSTRUP00000014748.1
UniProt Accession H2SQR1; H2SQR1_TAKRU
Protein Name Tyrosine-protein kinase
Gene Name abl2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSTRUG00000006070.1 ENSTRUT00000014816.1 ENSTRUP00000014748.1
ENSTRUG00000006070.1 ENSTRUT00000014817.1 ENSTRUP00000014749.1
ENSTRUG00000006070.1 ENSTRUT00000014818.1 ENSTRUP00000014750.1
ENSTRUG00000006070.1 ENSTRUT00000014819.1 ENSTRUP00000014751.1
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 5.20e-12 46.8 125 182
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            +++ +lyd+ a+ d++L+++kG++++v+  ++q+++W +     ++ +G +P+n+++ ++
   Q: 125  PNLFVALYDFVASGDNTLSITKGEKLRVL-GYNQNGEWSEV--RSKNGQGWVPSNYITPVN 182
           67899************************.*********98..788899*********997 PP
   
Organism Takifugu rubripes
Protein Sequence
(Fasta)
MGQQVGRVGE GTSTGLQPPQ PHATQTHQAK GIRGSGAGRR PREPGSITGT PPSRTPAVNV 60
PDPGINIFTQ HSDYSVCVED NTLSTEIPCC PKALHRPFGL DSAALTEAVR WSSKENLLGA 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Tru-118410|UBD,SH3|Takifugu rubripes
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGGGCAGC AGGTAGGCCG CGTCGGTGAG GGCACGTCGA CCGGACTCCA GCCACCACAG 60
CCCCACGCGA CCCAGACGCA CCAAGCGAAG GGGATCCGGG GGAGCGGCGC CGGGAGAAGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Tru-118410|UBD,SH3|Takifugu rubripes
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase
Interpro

IPR015015--F-actin_binding
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom
PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3
Pfam

PF08919--F_actin_bind
PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1
PRINTS

PR00401--SH2DOMAIN
PR00109--TYRKINASE
SMART

SM00808--FABD
SM00252--SH2
SM00326--SH3
SM00219--TyrKc
Gene Ontology

GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0005102--F:receptor binding
GO:0030154--P:cell differentiation
GO:0045087--P:innate immune response
GO:0038083--P:peptidyl-tyrosine autophosphorylation
GO:0042127--P:regulation of cell proliferation
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002263 Ailuropoda melanoleuca 68.57 0.00e+00 1385.00
IUUC-Apl-003389 Anas platyrhynchos 67.65 0.00e+00 1341.00
IUUC-Ame-010629 Astyanax mexicanus 66.09 0.00e+00 1236.00
IUUC-Bta-013370 Bos taurus 65.76 0.00e+00 1402.00
IUUC-Cja-018894 Callithrix jacchus 67.65 0.00e+00 1385.00
IUUC-Cfa-020398 Canis familiaris 82.83 0.00e+00 1082.00
IUUC-Cpo-022367 Cavia porcellus 67.16 0.00e+00 1307.00
IUUC-Csa-023386 Chlorocebus sabaeus 68.24 0.00e+00 1387.00
IUUC-Cho-024714 Choloepus hoffmanni 78.08 0.00e+00 1149.00
IUUC-Dre-027741 Danio rerio 76.03 0.00e+00 1615.00
IUUC-Dno-029246 Dasypus novemcinctus 64.77 0.00e+00 1356.00
IUUC-Dor-030416 Dipodomys ordii 61.19 0.00e+00 1244.00
IUUC-Dme-032098 Drosophila melanogaster 71.64 0.00e+00 741.00
IUUC-Ete-032899 Echinops telfairi 76.40 1.00e-130 461.00
IUUC-Eca-033387 Equus caballus 66.95 0.00e+00 1369.00
IUUC-Eeu-035058 Erinaceus europaeus 60.80 0.00e+00 1293.00
IUUC-Fca-036578 Felis catus 71.69 0.00e+00 1155.00
IUUC-Fal-037491 Ficedula albicollis 68.39 0.00e+00 1413.00
IUUC-Gmo-038509 Gadus morhua 82.96 0.00e+00 1383.00
IUUC-Gga-040638 Gallus gallus 67.59 0.00e+00 1368.00
IUUC-Gac-042550 Gasterosteus aculeatus 83.82 0.00e+00 1754.00
IUUC-Ggo-044487 Gorilla gorilla 65.55 0.00e+00 1410.00
IUUC-Hsa-046636 Homo sapiens 65.71 0.00e+00 1410.00
IUUC-Itr-048685 Ictidomys tridecemlineatus 67.63 0.00e+00 1388.00
IUUC-Lch-049530 Latimeria chalumnae 73.21 0.00e+00 1312.00
IUUC-Loc-051933 Lepisosteus oculatus 76.75 0.00e+00 1564.00
IUUC-Laf-053802 Loxodonta africana 65.90 0.00e+00 1448.00
IUUC-Mcc-054836 Macaca mulatta 66.00 0.00e+00 1412.00
IUUC-Mga-059277 Meleagris gallopavo 68.20 0.00e+00 1379.00
IUUC-Mmr-061206 Microcebus murinus 65.87 0.00e+00 1368.00
IUUC-Mdo-062281 Monodelphis domestica 77.91 0.00e+00 1087.00
IUUC-Mmu-063847 Mus musculus 66.00 0.00e+00 1387.00
IUUC-Mac-064539 Musa acuminata 31.47 8.00e-19 89.40
IUUC-Mpu-066309 Mustela putorius furo 78.88 0.00e+00 1120.00
IUUC-Mlu-068070 Myotis lucifugus 68.19 0.00e+00 1378.00
IUUC-Nle-070062 Nomascus leucogenys 78.11 0.00e+00 1109.00
IUUC-Ont-072440 Oreochromis niloticus 87.29 0.00e+00 1872.00
IUUC-Oan-073526 Ornithorhynchus anatinus 73.25 0.00e+00 1267.00
IUUC-Ocu-074051 Oryctolagus cuniculus 72.55 0.00e+00 1231.00
IUUC-Oni-082734 Oryza nivara 34.55 5.00e-24 106.00
IUUC-Opu-083538 Oryza punctata 35.00 1.00e-23 105.00
IUUC-Ola-086752 Oryzias latipes 98.70 0.00e+00 936.00
IUUC-Oga-088767 Otolemur garnettii 62.54 0.00e+00 1186.00
IUUC-Oar-089800 Ovis aries 68.33 0.00e+00 1377.00
IUUC-Ptr-090857 Pan troglodytes 78.11 0.00e+00 1110.00
IUUC-Pan-092279 Papio anubis 65.33 0.00e+00 1398.00
IUUC-Psi-093573 Pelodiscus sinensis 67.70 0.00e+00 1347.00
IUUC-Pma-094420 Petromyzon marinus 74.34 0.00e+00 858.00
IUUC-Pfo-096543 Poecilia formosa 81.11 0.00e+00 1692.00
IUUC-Pab-097949 Pongo abelii 65.12 0.00e+00 1367.00
IUUC-Pca-100370 Procavia capensis 61.82 0.00e+00 930.00
IUUC-Pva-103220 Pteropus vampyrus 63.19 0.00e+00 1092.00
IUUC-Rno-105924 Rattus norvegicus 65.41 0.00e+00 1370.00
IUUC-Sha-107114 Sarcophilus harrisii 74.23 0.00e+00 1140.00
IUUC-Sit-110444 Setaria italica 33.67 1.00e-20 95.10
IUUC-Ssc-115968 Sus scrofa 68.69 0.00e+00 1297.00
IUUC-Tgu-117301 Taeniopygia guttata 68.72 0.00e+00 1401.00
IUUC-Tni-119991 Tetraodon nigroviridis 94.13 0.00e+00 2129.00
IUUC-Tca-121389 Theobroma cacao 33.85 1.00e-23 105.00
IUUC-Tbe-127362 Tupaia belangeri 64.30 0.00e+00 1351.00
IUUC-Ttr-129291 Tursiops truncatus 67.37 0.00e+00 1385.00
IUUC-Vpa-130800 Vicugna pacos 75.15 0.00e+00 1203.00
IUUC-Xtr-132965 Xenopus tropicalis 66.43 0.00e+00 1172.00
Created Date 25-Jun-2017

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