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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-063800
Ensembl Protein ID ENSMUSP00000110435.1
UniProt Accession Q5DQR4; Q3TSM3; Q3UVG2; Q5DQR1; Q5DQR2; Q5DQR3; Q8BS52; STB5L_MOUSE
Genbank Protein ID AAT68171.1; AAT68171.1; AAT68171.1; AAT68171.1; AAT68171.1; AAT68171.1; AAT68171.1; AAT68171.1; AAT68171.1; AAT68171.1; AAT68171.1; AAT68171.1; AAT68171.1; AAT68171.1; AAT68171.1; AAT68171.1; AAT68171.1; AAT68171.1; AAT68171.1; AAT68171.1; AAT68171.1; AAT68171.1; AAT68171.1; AAT68171.1; AAT68171.1; AAT68171.1; AAT68171.1; AAT68172.1; AAT68172.1; AAT68172.1; AAT68172.1; AAT68172.1; AAT68172.1; AAT68172.1; AAT68172.1; AAT68172.1; AAT68172.1; AAT68172.1; AAT68172.1; AAT68172.1; AAT68172.1; AAT68172.1; AAT68172.1; AAT68172.1; AAT68172.1; AAT68
Protein Name Syntaxin-binding protein 5-like; Lethal(2) giant larvae protein homolog 4; Tomosyn-2
Genbank Nucleotide ID AY542354; AY542328; AY542329; AY542331; AY542330; AY542332; AY542334; AY542336; AY542338; AY542340; AY542349; AY542348; AY542347; AY542346; AY542345; AY542344; AY542343; AY542342; AY542341; AY542353; AY542352; AY542351; AY542350; AY542339; AY542337; AY542335; AY542333; AY542354; AY542328; AY542329; AY542330; AY542332; AY542335; AY542334; AY542333; AY542331; AY542336; AY542345; AY542344; AY542343; AY542342; AY542341; AY542340; AY542339; AY542338; AY542337; AY542353; AY542352; AY542351; AY542350; AY542349; AY542347; AY542354; AY542328; AY542329; AY542
Gene Name Stxbp5l; Llgl4
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000022829.14 ENSMUST00000114782.7 ENSMUSP00000110430.1
ENSMUSG00000022829.14 ENSMUST00000114780.7 ENSMUSP00000110428.1
ENSMUSG00000022829.14 ENSMUST00000114781.7 ENSMUSP00000110429.1
ENSMUSG00000022829.14 ENSMUST00000023526.8 ENSMUSP00000023526.2
ENSMUSG00000022829.14 ENSMUST00000114787.7 ENSMUSP00000110435.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemiRTarBasemicroRNATRANSFAC
RepTarRAID2
Protein-protein Interaction
IIDHINTMentha
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
Phospho.ELMUniProtPHOSIDAmUbiSiDa
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 8.20e-15 55.5 112 143
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 5    svtclaf..sdtllvsGsdDgtikvWDlrtgv 34
            v  l+f  +++ lvs+s D t+++W+lr+ +
   Q: 112  AVLQLQFliNEGALVSASSDDTLHLWNLRQKR 143
           4888999999999***************9865 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     May play a role in vesicle trafficking and exocytosis.
 May play a role in vesicle trafficking and exocytosis.
Protein Sequence
(Fasta)
MKKFNFRKVL DGLTASSPGS GSSSGSNSGG AGSGSVHPGG TAGLPREEIQ ESLTSDYFQI 60
CKTVRHGFPY QPTALAFDPV QKILAIGTRT GAIRILGRPG VDCYCQHESG AAVLQLQFLI 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063800|E3,WD_repeat|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCTCGGTTAG GACCTCGGAG AGCGCCAGGC ACCAGGACCA GAGGGACCCG AGAAGCGGCC 60
GGATCCGGGC TGGACCTTCG CCCGCCTGTG AGCCTGCAGC CTCCGCGCCC TCCGCCTCAC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063800|E3,WD_repeat|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0007--Acetylation
KW-0025--Alternative splicing
KW-1003--Cell membrane
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0268--Exocytosis
KW-0472--Membrane
KW-0488--Methylation
KW-0597--Phosphoprotein
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat
Interpro

IPR000664--Lethal2_giant
IPR013905--Lgl_C_dom
IPR013577--LLGL2
IPR001388--Synaptobrevin
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS50892--V_SNARE
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF08596--Lgl_C
PF08366--LLGL
PF00400--WD40
PRINTS

PR00962--LETHAL2GIANT
SMART

SM00320--WD40
Gene Ontology

GO:0005737--C:cytoplasm
GO:0016021--C:integral component of membrane
GO:0005886--C:plasma membrane
GO:0005096--F:GTPase activator activity
GO:0017137--F:Rab GTPase binding
GO:0019905--F:syntaxin binding
GO:0006887--P:exocytosis
GO:0042593--P:glucose homeostasis
GO:0046676--P:negative regulation of insulin secretion
GO:0050714--P:positive regulation of protein secretion
GO:0015031--P:protein transport
GO:0017157--P:regulation of exocytosis
KEGG mmu:207227
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Atr-002583 Amborella trichopoda 26.18 1.00e-21 99.00
IUUC-Apl-003824 Anas platyrhynchos 80.51 0.00e+00 1741.00
IUUC-Aca-004971 Anolis carolinensis 78.87 0.00e+00 1700.00
IUUC-Ath-007643 Arabidopsis thaliana 22.74 6.00e-21 96.70
IUUC-Acl-008044 Aspergillus clavatus 20.55 9.00e-15 76.30
IUUC-Afl-008612 Aspergillus flavus 22.66 2.00e-14 75.50
IUUC-Afu-008901 Aspergillus fumigatus 22.97 2.00e-16 81.60
IUUC-Ani-009223 Aspergillus nidulans 23.58 5.00e-17 83.60
IUUC-Ang-009861 Aspergillus niger 21.61 1.00e-15 79.00
IUUC-Aor-010078 Aspergillus oryzae 22.66 2.00e-14 75.10
IUUC-Ate-010462 Aspergillus terreus 23.51 1.00e-14 75.50
IUUC-Bgr-012214 Blumeria graminis 23.17 9.00e-10 59.70
IUUC-Bta-013516 Bos taurus 94.86 0.00e+00 2195.00
IUUC-Bdi-015011 Brachypodium distachyon 20.49 4.00e-19 90.50
IUUC-Bol-015788 Brassica oleracea 23.90 4.00e-24 107.00
IUUC-Bra-017845 Brassica rapa 23.90 2.00e-24 108.00
IUUC-Cja-019607 Callithrix jacchus 95.46 0.00e+00 1966.00
IUUC-Cfa-020684 Canis familiaris 94.86 0.00e+00 2199.00
IUUC-Cpo-021931 Cavia porcellus 90.64 0.00e+00 2015.00
IUUC-Csa-024071 Chlorocebus sabaeus 94.94 0.00e+00 2290.00
IUUC-Cho-025086 Choloepus hoffmanni 87.35 0.00e+00 2000.00
IUUC-Dre-028232 Danio rerio 70.64 0.00e+00 1569.00
IUUC-Dno-029242 Dasypus novemcinctus 94.52 0.00e+00 2205.00
IUUC-Dor-030660 Dipodomys ordii 88.36 0.00e+00 2040.00
IUUC-Dse-031263 Dothistroma septosporum 25.54 1.00e-13 72.40
IUUC-Ete-033006 Echinops telfairi 79.50 0.00e+00 1233.00
IUUC-Eeu-034943 Erinaceus europaeus 97.28 0.00e+00 843.00
IUUC-Fca-036345 Felis catus 89.49 0.00e+00 1473.00
IUUC-Fal-036915 Ficedula albicollis 84.63 0.00e+00 2038.00
IUUC-Gga-040529 Gallus gallus 86.58 0.00e+00 2052.00
IUUC-Gac-042416 Gasterosteus aculeatus 71.15 0.00e+00 1609.00
IUUC-Gma-043398 Glycine max 24.19 2.00e-22 102.00
IUUC-Ggo-044575 Gorilla gorilla 95.19 0.00e+00 2309.00
IUUC-Hsa-045781 Homo sapiens 95.45 0.00e+00 2315.00
IUUC-Hvu-047650 Hordeum vulgare 20.00 2.00e-20 94.40
IUUC-Lch-050258 Latimeria chalumnae 81.57 0.00e+00 1525.00
IUUC-Lpe-051115 Leersia perrieri 20.86 7.00e-20 93.20
IUUC-Loc-051905 Lepisosteus oculatus 76.74 0.00e+00 1310.00
IUUC-Lma-053029 Leptosphaeria maculans 24.27 8.00e-18 86.30
IUUC-Laf-053669 Loxodonta africana 92.49 0.00e+00 2161.00
IUUC-Mcc-055188 Macaca mulatta 94.94 0.00e+00 2291.00
IUUC-Meu-056246 Macropus eugenii 77.84 0.00e+00 1146.00
IUUC-Mmr-061273 Microcebus murinus 88.91 0.00e+00 2128.00
IUUC-Mdo-062223 Monodelphis domestica 92.48 0.00e+00 1964.00
IUUC-Mac-065436 Musa acuminata 29.32 2.00e-13 72.40
IUUC-Mlu-067278 Myotis lucifugus 93.76 0.00e+00 2235.00
IUUC-Nfi-068318 Neosartorya fischeri 23.17 1.00e-16 82.00
IUUC-Nle-069733 Nomascus leucogenys 95.36 0.00e+00 2311.00
IUUC-Opr-070840 Ochotona princeps 80.02 0.00e+00 1220.00
IUUC-Ocu-074214 Oryctolagus cuniculus 95.19 0.00e+00 2237.00
IUUC-Oru-084893 Oryza rufipogon 20.86 9.00e-17 82.80
IUUC-Ola-087301 Oryzias latipes 73.88 0.00e+00 1569.00
IUUC-Oga-089148 Otolemur garnettii 92.75 0.00e+00 2215.00
IUUC-Oar-090261 Ovis aries 94.71 0.00e+00 2162.00
IUUC-Ptr-090697 Pan troglodytes 95.45 0.00e+00 2315.00
IUUC-Pan-092899 Papio anubis 94.95 0.00e+00 2284.00
IUUC-Psi-093249 Pelodiscus sinensis 85.08 0.00e+00 1964.00
IUUC-Pfo-096605 Poecilia formosa 70.87 0.00e+00 1392.00
IUUC-Pab-097774 Pongo abelii 90.56 0.00e+00 1711.00
IUUC-Pop-099413 Populus trichocarpa 21.61 2.00e-16 82.00
IUUC-Pva-102704 Pteropus vampyrus 83.21 0.00e+00 1877.00
IUUC-Pte-104412 Pyrenophora teres 24.08 5.00e-18 87.00
IUUC-Pyt-104770 Pyrenophora triticirepentis 24.08 1.00e-17 85.90
IUUC-Rno-105297 Rattus norvegicus 98.81 0.00e+00 2173.00
IUUC-Sha-107086 Sarcophilus harrisii 87.44 0.00e+00 1878.00
IUUC-Sly-111338 Solanum lycopersicum 27.52 4.00e-21 95.50
IUUC-Stu-112417 Solanum tuberosum 28.29 1.00e-21 97.80
IUUC-Tgu-117382 Taeniopygia guttata 85.34 0.00e+00 1758.00
IUUC-Tru-118317 Takifugu rubripes 73.51 0.00e+00 1634.00
IUUC-Tsy-119322 Tarsius syrichta 88.75 0.00e+00 1365.00
IUUC-Tca-121778 Theobroma cacao 20.62 1.00e-20 95.50
IUUC-Tre-122192 Trichoderma reesei 22.81 4.00e-17 84.00
IUUC-Tae-125452 Triticum aestivum 20.49 8.00e-21 96.30
IUUC-Tur-126560 Triticum urartu 20.29 1.00e-17 85.50
IUUC-Ttr-129239 Tursiops truncatus 94.93 0.00e+00 2161.00
IUUC-Vpa-130524 Vicugna pacos 88.87 0.00e+00 1999.00
IUUC-Xtr-132634 Xenopus tropicalis 76.71 0.00e+00 1818.00
IUUC-Xma-133316 Xiphophorus maculatus 67.72 0.00e+00 1642.00
Created Date 25-Jun-2017

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