iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Itr-048069

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01124112

Gene Name

TRIM6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000024836.1	ENSSTOT00000029858.1	ENSSTOP00000022671.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.40e-06	28.7	5	41

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 10   dgplvlpCgHvfhadCl..qkwpglknssskefrCPlCr 46
           + p++++CgH f++ C+  ++   +  s+ ke +CP+C+
   Q: 5    E-PVSTDCGHSFCQACIteNR-EESEMSQDKERNCPVCQ 41
           4.999************8533.578889**********7 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

ELLTEPVSTD CGHSFCQACI TENREESEMS QDKERNCPVC QTSYQPRNLR PNRHLANIAQ 60
RLREVVLCPG KQLQVILCAH HGEKLQLFCK EDGKLICWLC ERSQEHRGHH TFLMEEVAQE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGCTCCTGA CCGAACCCGT GAGCACAGAC TGTGGCCACA GCTTCTGCCA GGCCTGCATC 60
ACAGAGAATA GAGAGGAATC AGAGATGAGC CAGGACAAGG AGCGCAATTG TCCTGTGTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR010908--Longin_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0035458--P:cellular response to interferon-beta
GO:0098586--P:cellular response to virus
GO:0010994--P:free ubiquitin chain polymerization
GO:2000737--P:negative regulation of stem cell differentiation
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0045071--P:negative regulation of viral genome replication
GO:0002741--P:positive regulation of cytokine secretion involved in immune response
GO:0002230--P:positive regulation of defense response to virus by host
GO:0010628--P:positive regulation of gene expression
GO:0033138--P:positive regulation of peptidyl-serine phosphorylation
GO:0010800--P:positive regulation of peptidyl-threonine phosphorylation
GO:2000679--P:positive regulation of transcription regulatory region DNA binding
GO:0060340--P:positive regulation of type I interferon-mediated signaling pathway
GO:0000209--P:protein polyubiquitination
GO:0070206--P:protein trimerization
GO:0032496--P:response to lipopolysaccharide

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001965	Ailuropoda melanoleuca	76.97	0.00e+00	709.00
IUUC-Bta-013110	Bos taurus	51.36	3.00e-135	474.00
IUUC-Cja-019944	Callithrix jacchus	51.79	8.00e-126	443.00
IUUC-Cfa-021152	Canis familiaris	55.04	4.00e-132	465.00
IUUC-Cpo-021369	Cavia porcellus	54.32	2.00e-124	439.00
IUUC-Csa-023785	Chlorocebus sabaeus	55.74	7.00e-142	496.00
IUUC-Dno-029492	Dasypus novemcinctus	52.00	8.00e-129	454.00
IUUC-Dor-030480	Dipodomys ordii	75.44	4.00e-115	408.00
IUUC-Ete-033021	Echinops telfairi	46.12	5.00e-102	364.00
IUUC-Eca-034235	Equus caballus	53.77	2.00e-133	468.00
IUUC-Eeu-034968	Erinaceus europaeus	48.50	1.00e-102	366.00
IUUC-Fca-035533	Felis catus	77.61	0.00e+00	718.00
IUUC-Ggo-044550	Gorilla gorilla	52.74	2.00e-131	462.00
IUUC-Hsa-046006	Homo sapiens	79.74	0.00e+00	769.00
IUUC-Laf-053805	Loxodonta africana	76.55	0.00e+00	671.00
IUUC-Mcc-054743	Macaca mulatta	53.86	1.00e-136	479.00
IUUC-Mmr-061023	Microcebus murinus	78.85	0.00e+00	708.00
IUUC-Mmu-063682	Mus musculus	80.38	0.00e+00	762.00
IUUC-Mpu-065842	Mustela putorius furo	78.21	0.00e+00	714.00
IUUC-Mlu-067658	Myotis lucifugus	56.21	9.00e-130	457.00
IUUC-Nle-068980	Nomascus leucogenys	53.43	2.00e-135	475.00
IUUC-Opr-071057	Ochotona princeps	49.35	5.00e-110	390.00
IUUC-Ocu-073956	Oryctolagus cuniculus	49.78	5.00e-117	414.00
IUUC-Oga-088267	Otolemur garnettii	79.96	0.00e+00	741.00
IUUC-Oar-089984	Ovis aries	55.77	6.00e-129	454.00
IUUC-Ptr-090573	Pan troglodytes	79.53	0.00e+00	769.00
IUUC-Pan-092745	Papio anubis	79.74	0.00e+00	753.00
IUUC-Pab-098535	Pongo abelii	53.43	3.00e-135	474.00
IUUC-Pca-100258	Procavia capensis	55.79	7.00e-129	454.00
IUUC-Pva-102482	Pteropus vampyrus	55.60	4.00e-126	445.00
IUUC-Rno-105401	Rattus norvegicus	80.81	0.00e+00	765.00
IUUC-Spo-108196	Schizosaccharomyces pombe	38.46	2.00e-04	38.90
IUUC-Sar-113094	Sorex araneus	46.61	3.00e-97	348.00
IUUC-Ssc-115715	Sus scrofa	50.73	3.00e-121	428.00
IUUC-Tsy-119330	Tarsius syrichta	51.57	2.00e-121	429.00
IUUC-Tbe-127868	Tupaia belangeri	52.73	1.00e-122	433.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence