iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-022032

Ensembl Protein ID

ENSCPOP00000008708.2

UniProt Accession

H0VF76; H0VF76_CAVPO

Genbank Protein ID

ENSCPOP00000008708

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02012469

Gene Name

TNK2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000009702.3	ENSCPOT00000009789.2	ENSCPOP00000008708.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	87.86	0.00e+00	1626.00	IUUC-Hsa-046670
UBD/Alpha-Helix/UBA	90.32	0.00e+00	1695.00	IUUC-Mmu-063861

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MQPEEGTGWL LELLSEVQLQ QYFLRLRDDL NVTRLSHFEY VKNEDLEKIG MGRPGQRRLW 60
EAVKRRKALC KRKSWMSKVF SGKRLEAEFP PHHSQSTFRK PSPTPGAPAS EGPLQSLTCL 120

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Nucleotide Sequence
(Fasta)

ATGCAGCCTG AGGAAGGCAC GGGCTGGCTG TTGGAGCTGC TCTCCGAGGT GCAGCTCCAG 60
CAGTACTTCC TGCGGCTCCG AGATGACCTC AACGTGACTC GCCTGTCCCA CTTTGAGTAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR015116--Cdc42_binding_dom-like
IPR011009--Kinase-like_dom
IPR021619--Mig-6
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50002--SH3

Pfam

PF09027--GTPase_binding
PF11555--Inhibitor_Mig-6
PF07714--Pkinase_Tyr
PF14604--SH3_9

PRINTS

PR00109--TYRKINASE

SMART

SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005905--C:clathrin-coated pit
GO:0030136--C:clathrin-coated vesicle
GO:0070436--C:Grb2-EGFR complex
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0004712--F:protein serine/threonine/tyrosine kinase activity
GO:0004713--F:protein tyrosine kinase activity
GO:0050731--P:positive regulation of peptidyl-tyrosine phosphorylation
GO:2000369--P:regulation of clathrin-dependent endocytosis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002166	Ailuropoda melanoleuca	88.86	0.00e+00	1602.00
IUUC-Aca-004315	Anolis carolinensis	88.97	2.00e-73	268.00
IUUC-Ame-011350	Astyanax mexicanus	55.42	0.00e+00	1040.00
IUUC-Bta-012325	Bos taurus	87.46	0.00e+00	1655.00
IUUC-Cel-018130	Caenorhabditis elegans	36.48	2.00e-89	323.00
IUUC-Cja-019545	Callithrix jacchus	82.60	0.00e+00	1498.00
IUUC-Cfa-020706	Canis familiaris	87.78	0.00e+00	1664.00
IUUC-Csa-023936	Chlorocebus sabaeus	89.56	0.00e+00	1659.00
IUUC-Csv-026328	Ciona savignyi	57.77	6.00e-173	600.00
IUUC-Dre-028714	Danio rerio	63.64	0.00e+00	1204.00
IUUC-Dno-029525	Dasypus novemcinctus	90.97	0.00e+00	1483.00
IUUC-Dme-031778	Drosophila melanogaster	55.90	2.00e-144	507.00
IUUC-Ete-032225	Echinops telfairi	90.20	0.00e+00	852.00
IUUC-Fca-035664	Felis catus	89.11	0.00e+00	1706.00
IUUC-Gmo-039543	Gadus morhua	58.21	0.00e+00	943.00
IUUC-Gga-040241	Gallus gallus	67.86	0.00e+00	1263.00
IUUC-Gac-041457	Gasterosteus aculeatus	67.41	0.00e+00	1055.00
IUUC-Ggo-045333	Gorilla gorilla	90.03	0.00e+00	1637.00
IUUC-Hsa-046670	Homo sapiens	88.05	0.00e+00	1604.00
IUUC-Itr-048054	Ictidomys tridecemlineatus	89.94	0.00e+00	1688.00
IUUC-Lch-049670	Latimeria chalumnae	62.70	0.00e+00	1196.00
IUUC-Loc-052870	Lepisosteus oculatus	63.77	0.00e+00	1261.00
IUUC-Laf-053782	Loxodonta africana	87.48	0.00e+00	1607.00
IUUC-Mcc-055874	Macaca mulatta	89.66	0.00e+00	1655.00
IUUC-Mga-059717	Meleagris gallopavo	70.69	0.00e+00	1327.00
IUUC-Mdo-062270	Monodelphis domestica	86.36	0.00e+00	1427.00
IUUC-Mmu-063861	Mus musculus	90.80	0.00e+00	1733.00
IUUC-Mpu-066127	Mustela putorius furo	93.73	0.00e+00	1336.00
IUUC-Mlu-067937	Myotis lucifugus	89.47	0.00e+00	1322.00
IUUC-Nle-069298	Nomascus leucogenys	86.03	0.00e+00	1322.00
IUUC-Ont-072437	Oreochromis niloticus	58.23	0.00e+00	1179.00
IUUC-Oan-073708	Ornithorhynchus anatinus	71.91	1.00e-110	394.00
IUUC-Ola-087023	Oryzias latipes	58.96	0.00e+00	1090.00
IUUC-Pan-091857	Papio anubis	75.22	6.00e-83	300.00
IUUC-Psi-093401	Pelodiscus sinensis	55.35	8.00e-149	520.00
IUUC-Pfo-097455	Poecilia formosa	59.60	0.00e+00	1189.00
IUUC-Rno-105586	Rattus norvegicus	90.42	0.00e+00	1706.00
IUUC-Sha-106868	Sarcophilus harrisii	78.75	0.00e+00	1532.00
IUUC-Ssc-116250	Sus scrofa	87.86	0.00e+00	1605.00
IUUC-Tgu-116592	Taeniopygia guttata	70.01	0.00e+00	1293.00
IUUC-Tru-117852	Takifugu rubripes	69.98	1.00e-179	624.00
IUUC-Tsy-119087	Tarsius syrichta	88.39	6.00e-158	551.00
IUUC-Tni-120826	Tetraodon nigroviridis	63.20	0.00e+00	1228.00
IUUC-Xtr-132069	Xenopus tropicalis	65.38	0.00e+00	1156.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence