iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062270

Ensembl Protein ID

ENSMODP00000022973.3

UniProt Accession

F6XU33; F6XU33_MONDO

Protein Name

Uncharacterized protein

Gene Name

TNK2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000018423.3	ENSMODT00000023381.3	ENSMODP00000022973.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	85.63	0.00e+00	1594.00	IUUC-Hsa-046670
UBD/Alpha-Helix/UBA	85.92	0.00e+00	1623.00	IUUC-Mmu-063861

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MQHFTPLILP LSTERSMFRL FWRSKRLEGS SMQAEEGTGW LLELLAEVQL QQYFLRLRDD 60
LNITRLSHFE YVKNEDLEKI GMGRPGQRRL WEAVKRRKAM CKRKSWMSKV FSGKRLDAEF 120

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Nucleotide Sequence
(Fasta)

CGAACTCCTC CCTCCCCAGA ACAAAGAAAA AATTAAGCAA AGTCAACTGA TAGTGTATGC 60
AACATTTCAC CCCACTAATA CTCCCTCTCT CTACTGAAAG AAGTATGTTT CGTCTCTTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR015116--Cdc42_binding_dom-like
IPR011009--Kinase-like_dom
IPR021619--Mig-6
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom
IPR009060--UBA-like

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50002--SH3

Pfam

PF09027--GTPase_binding
PF11555--Inhibitor_Mig-6
PF07714--Pkinase_Tyr
PF14604--SH3_9

PRINTS

PR00109--TYRKINASE

SMART

SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005905--C:clathrin-coated pit
GO:0030136--C:clathrin-coated vesicle
GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0070436--C:Grb2-EGFR complex
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0004712--F:protein serine/threonine/tyrosine kinase activity
GO:0005102--F:receptor binding
GO:0030154--P:cell differentiation
GO:0016477--P:cell migration
GO:0045087--P:innate immune response
GO:0038083--P:peptidyl-tyrosine autophosphorylation
GO:0050731--P:positive regulation of peptidyl-tyrosine phosphorylation
GO:0042127--P:regulation of cell proliferation
GO:2000369--P:regulation of clathrin-dependent endocytosis
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002166	Ailuropoda melanoleuca	86.75	0.00e+00	1581.00
IUUC-Aca-004315	Anolis carolinensis	88.97	2.00e-73	267.00
IUUC-Ame-011350	Astyanax mexicanus	54.74	0.00e+00	1038.00
IUUC-Bta-012325	Bos taurus	85.62	0.00e+00	1639.00
IUUC-Cel-018130	Caenorhabditis elegans	37.15	2.00e-90	327.00
IUUC-Cja-019545	Callithrix jacchus	80.19	0.00e+00	1481.00
IUUC-Cfa-020706	Canis familiaris	86.18	0.00e+00	1643.00
IUUC-Cpo-022032	Cavia porcellus	81.17	0.00e+00	1579.00
IUUC-Csa-023936	Chlorocebus sabaeus	87.03	0.00e+00	1622.00
IUUC-Csv-026328	Ciona savignyi	58.23	1.00e-172	598.00
IUUC-Dre-028714	Danio rerio	64.05	0.00e+00	1219.00
IUUC-Dno-029525	Dasypus novemcinctus	86.21	0.00e+00	1644.00
IUUC-Dme-031778	Drosophila melanogaster	55.68	8.00e-144	504.00
IUUC-Ete-032225	Echinops telfairi	88.02	0.00e+00	833.00
IUUC-Fca-035664	Felis catus	87.23	0.00e+00	1678.00
IUUC-Gmo-039543	Gadus morhua	63.23	0.00e+00	817.00
IUUC-Gga-040241	Gallus gallus	67.40	0.00e+00	1305.00
IUUC-Gac-041457	Gasterosteus aculeatus	62.01	0.00e+00	1102.00
IUUC-Ggo-045333	Gorilla gorilla	85.73	0.00e+00	1611.00
IUUC-Hsa-046670	Homo sapiens	86.20	0.00e+00	1577.00
IUUC-Itr-048054	Ictidomys tridecemlineatus	88.35	0.00e+00	1639.00
IUUC-Lch-049670	Latimeria chalumnae	63.22	0.00e+00	1228.00
IUUC-Loc-052870	Lepisosteus oculatus	64.81	0.00e+00	1298.00
IUUC-Laf-053782	Loxodonta africana	85.62	0.00e+00	1589.00
IUUC-Mcc-055874	Macaca mulatta	87.31	0.00e+00	1608.00
IUUC-Mga-059717	Meleagris gallopavo	70.83	0.00e+00	1365.00
IUUC-Mmu-063861	Mus musculus	87.61	0.00e+00	1677.00
IUUC-Mpu-066127	Mustela putorius furo	91.44	0.00e+00	1306.00
IUUC-Mlu-067937	Myotis lucifugus	88.06	0.00e+00	1277.00
IUUC-Nle-069298	Nomascus leucogenys	84.78	0.00e+00	1310.00
IUUC-Ont-072437	Oreochromis niloticus	68.08	0.00e+00	981.00
IUUC-Oan-073708	Ornithorhynchus anatinus	66.67	0.00e+00	692.00
IUUC-Ola-087023	Oryzias latipes	61.31	0.00e+00	1147.00
IUUC-Pan-091857	Papio anubis	83.70	5.00e-86	310.00
IUUC-Psi-093401	Pelodiscus sinensis	54.75	2.00e-147	516.00
IUUC-Pfo-097455	Poecilia formosa	68.04	0.00e+00	993.00
IUUC-Rno-105586	Rattus norvegicus	87.32	0.00e+00	1645.00
IUUC-Sha-106868	Sarcophilus harrisii	94.04	0.00e+00	1385.00
IUUC-Ssc-116250	Sus scrofa	84.98	0.00e+00	1576.00
IUUC-Tgu-116592	Taeniopygia guttata	69.66	0.00e+00	1316.00
IUUC-Tru-117852	Takifugu rubripes	71.55	0.00e+00	629.00
IUUC-Tsy-119087	Tarsius syrichta	93.40	1.00e-158	553.00
IUUC-Tni-120826	Tetraodon nigroviridis	63.80	0.00e+00	1221.00
IUUC-Xtr-132069	Xenopus tropicalis	65.60	0.00e+00	1194.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence