iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003322

Ensembl Protein ID

ENSAPLP00000008224.1

UniProt Accession

U3ILV2; U3ILV2_ANAPL

Genbank Protein ID

ENSAPLP00000008224

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01022295

Gene Name

GRB2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000008555.1	ENSAPLT00000008898.1	ENSAPLP00000008224.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.30e-25	86.9	131	188

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +  +vq+l+d+++q+++eL +++Gd+++v+  ++ d +W+kg    +g+ G+fP n+v+ ++
   Q: 131  QPTYVQALFDFDPQEEGELGFRRGDFIQVL--DNSDPNWWKG--ACHGQTGMFPRNYVTPVN 188
           5689**************************..9*********..8**************997 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

VLNEECDQNW YKAELNGKDG FIPKNYIEMK PHPWFFGKIP RAKAEEMLGK QRHDGAFLIR 60
ESESAPGDFS LSVKFGNDVQ HFKVLRDGAG KYFLWVVKFN SLNELVDYHR STSVSRNQQI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCATGGAAGC CATCGCCAAG TACGACTTCA AAGCCACGGC GGATGACGAG CTGAGCTTCA 60
AACGGGGAGA TATCCTTAAG GTGAGTGGAG GGGAAGGGCT CGGGGTTCGC GCTCTGGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR000980--SH2
IPR001452--SH3_domain

PROSITE

PS50001--SH2
PS50002--SH3

Pfam

PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005911--C:cell-cell junction
GO:0008180--C:COP9 signalosome
GO:0005768--C:endosome
GO:0070062--C:extracellular exosome
GO:0070436--C:Grb2-EGFR complex
GO:0005730--C:nucleolus
GO:0005654--C:nucleoplasm
GO:0012506--C:vesicle membrane
GO:0003723--F:RNA binding
GO:0048646--P:anatomical structure formation involved in morphogenesis
GO:0030154--P:cell differentiation
GO:0071479--P:cellular response to ionizing radiation
GO:0008286--P:insulin receptor signaling pathway
GO:0030838--P:positive regulation of actin filament polymerization
GO:2000379--P:positive regulation of reactive oxygen species metabolic process
GO:0009967--P:positive regulation of signal transduction
GO:0031623--P:receptor internalization
GO:0043408--P:regulation of MAPK cascade
GO:0042770--P:signal transduction in response to DNA damage

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001345	Ailuropoda melanoleuca	97.38	2.00e-111	393.00
IUUC-Aca-005193	Anolis carolinensis	100.00	6.00e-114	402.00
IUUC-Ago-007965	Ashbya gossypii	50.00	5.00e-13	67.40
IUUC-Ame-010929	Astyanax mexicanus	94.24	3.00e-108	383.00
IUUC-Bta-012932	Bos taurus	97.38	6.00e-112	395.00
IUUC-Cel-018665	Caenorhabditis elegans	57.07	5.00e-61	226.00
IUUC-Cja-019225	Callithrix jacchus	97.38	6.00e-112	395.00
IUUC-Cfa-020887	Canis familiaris	97.38	6.00e-112	395.00
IUUC-Cpo-022488	Cavia porcellus	97.38	6.00e-112	395.00
IUUC-Csa-023326	Chlorocebus sabaeus	97.38	6.00e-112	395.00
IUUC-Cho-024953	Choloepus hoffmanni	96.67	2.00e-85	307.00
IUUC-Cin-025144	Ciona intestinalis	60.75	4.00e-61	227.00
IUUC-Csv-026210	Ciona savignyi	60.00	4.00e-60	223.00
IUUC-Dre-028403	Danio rerio	95.29	8.00e-110	389.00
IUUC-Dno-029120	Dasypus novemcinctus	96.86	4.00e-111	392.00
IUUC-Dor-030763	Dipodomys ordii	97.38	6.00e-112	395.00
IUUC-Dme-031741	Drosophila melanogaster	63.44	3.00e-66	244.00
IUUC-Ete-032354	Echinops telfairi	64.21	2.00e-65	241.00
IUUC-Eca-033222	Equus caballus	97.38	6.00e-112	395.00
IUUC-Eeu-034513	Erinaceus europaeus	67.54	9.00e-71	259.00
IUUC-Fca-036294	Felis catus	97.38	6.00e-112	395.00
IUUC-Fal-037130	Ficedula albicollis	98.95	2.00e-112	397.00
IUUC-Gmo-039546	Gadus morhua	95.29	4.00e-109	386.00
IUUC-Gga-041139	Gallus gallus	100.00	6.00e-114	402.00
IUUC-Gac-041968	Gasterosteus aculeatus	97.38	3.00e-111	393.00
IUUC-Ggo-044562	Gorilla gorilla	97.38	6.00e-112	395.00
IUUC-Hsa-046730	Homo sapiens	97.38	6.00e-112	395.00
IUUC-Itr-049025	Ictidomys tridecemlineatus	97.38	6.00e-112	395.00
IUUC-Lch-050230	Latimeria chalumnae	96.95	1.00e-72	266.00
IUUC-Loc-052723	Lepisosteus oculatus	96.86	1.00e-110	391.00
IUUC-Laf-053774	Loxodonta africana	95.81	1.00e-110	391.00
IUUC-Mcc-054603	Macaca mulatta	97.38	6.00e-112	395.00
IUUC-Meu-056173	Macropus eugenii	96.20	6.00e-90	322.00
IUUC-Mga-059950	Meleagris gallopavo	100.00	6.00e-114	402.00
IUUC-Mvi-060523	Microbotryum violaceum	48.15	2.00e-10	59.70
IUUC-Mmr-060878	Microcebus murinus	97.38	6.00e-112	395.00
IUUC-Mdo-062454	Monodelphis domestica	98.95	5.00e-113	399.00
IUUC-Mmu-063913	Mus musculus	96.86	1.00e-111	394.00
IUUC-Mpu-066125	Mustela putorius furo	97.38	6.00e-112	395.00
IUUC-Mlu-068007	Myotis lucifugus	97.38	6.00e-112	395.00
IUUC-Nle-069101	Nomascus leucogenys	97.38	6.00e-112	395.00
IUUC-Opr-071075	Ochotona princeps	97.38	6.00e-112	395.00
IUUC-Ont-072253	Oreochromis niloticus	92.15	7.00e-106	375.00
IUUC-Ocu-074583	Oryctolagus cuniculus	97.38	6.00e-112	395.00
IUUC-Ola-086586	Oryzias latipes	96.92	1.00e-71	262.00
IUUC-Oga-089047	Otolemur garnettii	97.38	6.00e-112	395.00
IUUC-Oar-089904	Ovis aries	89.58	4.00e-101	359.00
IUUC-Ptr-090678	Pan troglodytes	97.38	6.00e-112	395.00
IUUC-Pan-092090	Papio anubis	97.38	6.00e-112	395.00
IUUC-Psi-093765	Pelodiscus sinensis	99.48	3.00e-113	400.00
IUUC-Pma-094650	Petromyzon marinus	84.82	3.00e-97	347.00
IUUC-Pfo-096131	Poecilia formosa	95.81	5.00e-110	389.00
IUUC-Pab-098709	Pongo abelii	97.38	6.00e-112	395.00
IUUC-Pca-100581	Procavia capensis	96.34	2.00e-110	390.00
IUUC-Pva-103066	Pteropus vampyrus	97.38	6.00e-112	395.00
IUUC-Rno-105224	Rattus norvegicus	97.38	6.00e-112	395.00
IUUC-Sce-106302	Saccharomyces cerevisiae	53.70	7.00e-16	76.60
IUUC-Sha-107247	Sarcophilus harrisii	99.48	9.00e-113	398.00
IUUC-Sar-113277	Sorex araneus	96.20	3.00e-90	323.00
IUUC-Ssc-115478	Sus scrofa	97.38	6.00e-112	395.00
IUUC-Tgu-117479	Taeniopygia guttata	98.95	2.00e-112	397.00
IUUC-Tru-118451	Takifugu rubripes	84.73	2.00e-92	331.00
IUUC-Tsy-119029	Tarsius syrichta	91.79	9.00e-68	248.00
IUUC-Tni-120563	Tetraodon nigroviridis	49.20	3.00e-52	197.00
IUUC-Tbe-128097	Tupaia belangeri	96.86	5.00e-111	392.00
IUUC-Ttr-128871	Tursiops truncatus	99.23	1.00e-74	271.00
IUUC-Vpa-130754	Vicugna pacos	97.38	6.00e-112	395.00
IUUC-Xtr-132275	Xenopus tropicalis	91.63	1.00e-108	385.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence