iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssc-116104

Ensembl Protein ID

ENSSSCP00000008732.2

UniProt Accession

F1STE9; F1STE9_PIG

Genbank Protein ID

ENSSSCP00000008732

Protein Name

DNA repair protein REV1

Genbank Nucleotide ID

CU694748

Gene Name

REV1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000008179.2	ENSSSCT00000008958.2	ENSSSCP00000008732.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBM	1.20e-21	75.9	1013	1041

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBM

   S: 1    lPsqvDpeVfsqLPeeiQeEvmaelrqqk 29
           ++sqvDpeVf++LP+e+Q+E++a+++q++
   Q: 1013 AFSQVDPEVFAALPAELQKELKAAYDQRQ 1041
           59*************************98 PP

Organism

Sus scrofa

Functional Description
(View)

Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.

Protein Sequence
(Fasta)

MRRGGWRKRA EDSWEKWGGY MAAKVQKLEQ QFRSDAAIQK DGTTSTIFSG VAIYVNGYTD 60
PSAEELRKLM MLHGGQYHVY YSRSKTTHII ATNLPNAKIK ELKGEKVIRP EWIVESIKAG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCTGTGTCT TTGACCTACA CCACAGCAAC CTGCAACCAC ATGGTCCCTA GCACTCAACT 60
TTTTTCTCAT CAGTTCCCGT AAGTCCTGAG AAGAAAGGTA GGGCAGAATA TTCTATTTTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0227--DNA damage
KW-0234--DNA repair
KW-0237--DNA synthesis
KW-0238--DNA-binding
KW-0548--Nucleotidyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR001357--BRCT_dom
IPR017961--DNA_pol_Y-fam_little_finger
IPR025527--DUF4414
IPR012112--REV1
IPR031991--Rev1_C
IPR001126--UmuC

PROSITE

PS50172--BRCT
PS50173--UMUC

Pfam

PF16589--BRCT_2
PF14377--DUF4414
PF00817--IMS
PF11799--IMS_C
PF16727--REV1_C

SMART

SM00292--BRCT

Gene Ontology

GO:0005634--C:nucleus
GO:0003684--F:damaged DNA binding
GO:0017125--F:deoxycytidyl transferase activity
GO:0042276--P:error-prone translesion synthesis
GO:0009411--P:response to UV

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000375	Aegilops tauschii	31.27	2.00e-31	131.00
IUUC-Aml-001185	Ailuropoda melanoleuca	88.37	0.00e+00	2138.00
IUUC-Atr-002915	Amborella trichopoda	33.39	2.00e-83	303.00
IUUC-Apl-004054	Anas platyrhynchos	74.70	0.00e+00	1788.00
IUUC-Aca-004304	Anolis carolinensis	68.07	0.00e+00	1663.00
IUUC-Aly-005696	Arabidopsis lyrata	34.27	2.00e-83	304.00
IUUC-Ath-006893	Arabidopsis thaliana	34.72	2.00e-84	307.00
IUUC-Ago-007722	Ashbya gossypii	28.32	2.00e-39	157.00
IUUC-Acl-008347	Aspergillus clavatus	34.34	3.00e-86	313.00
IUUC-Afl-008444	Aspergillus flavus	36.73	1.00e-86	314.00
IUUC-Afu-008837	Aspergillus fumigatus	31.13	4.00e-85	309.00
IUUC-Ani-009188	Aspergillus nidulans	38.35	6.00e-90	325.00
IUUC-Ang-009866	Aspergillus niger	33.66	6.00e-97	348.00
IUUC-Aor-010107	Aspergillus oryzae	36.73	2.00e-86	314.00
IUUC-Ate-010359	Aspergillus terreus	33.85	4.00e-91	329.00
IUUC-Ame-010664	Astyanax mexicanus	50.63	0.00e+00	1120.00
IUUC-Bgr-012244	Blumeria graminis	34.10	2.00e-78	287.00
IUUC-Bta-013405	Bos taurus	84.41	0.00e+00	1872.00
IUUC-Bci-013849	Botrytis cinerea	31.39	4.00e-87	316.00
IUUC-Bdi-014066	Brachypodium distachyon	37.29	5.00e-85	309.00
IUUC-Bol-015544	Brassica oleracea	36.00	1.00e-85	311.00
IUUC-Bra-017792	Brassica rapa	33.76	7.00e-81	295.00
IUUC-Cel-018148	Caenorhabditis elegans	36.01	9.00e-82	298.00
IUUC-Cja-019742	Callithrix jacchus	73.50	0.00e+00	1447.00
IUUC-Cfa-020112	Canis familiaris	88.38	0.00e+00	2150.00
IUUC-Cpo-022152	Cavia porcellus	81.51	0.00e+00	2040.00
IUUC-Cre-022951	Chlamydomonas reinhardtii	42.98	6.00e-40	159.00
IUUC-Csa-023504	Chlorocebus sabaeus	85.43	0.00e+00	2104.00
IUUC-Cho-024780	Choloepus hoffmanni	66.61	0.00e+00	725.00
IUUC-Cin-025276	Ciona intestinalis	42.59	1.00e-111	397.00
IUUC-Csv-026283	Ciona savignyi	44.24	3.00e-114	405.00
IUUC-Cgl-026726	Colletotrichum gloeosporioides	28.89	3.00e-90	326.00
IUUC-Cne-027079	Cryptococcus neoformans	34.97	2.00e-78	287.00
IUUC-Cme-027346	Cyanidioschyzon merolae	27.89	3.00e-44	174.00
IUUC-Dre-028073	Danio rerio	50.68	0.00e+00	1107.00
IUUC-Dno-030038	Dasypus novemcinctus	82.34	0.00e+00	2006.00
IUUC-Dor-031100	Dipodomys ordii	81.67	0.00e+00	1486.00
IUUC-Dse-031310	Dothistroma septosporum	33.45	4.00e-78	286.00
IUUC-Dme-031991	Drosophila melanogaster	41.85	7.00e-111	394.00
IUUC-Ete-033082	Echinops telfairi	75.05	0.00e+00	1371.00
IUUC-Eca-033471	Equus caballus	87.66	0.00e+00	2123.00
IUUC-Eeu-034993	Erinaceus europaeus	83.16	0.00e+00	1369.00
IUUC-Fca-035367	Felis catus	87.06	0.00e+00	2053.00
IUUC-Fal-036973	Ficedula albicollis	73.49	0.00e+00	1702.00
IUUC-Fox-037677	Fusarium oxysporum	30.83	2.00e-85	310.00
IUUC-Fso-038252	Fusarium solani	31.48	9.00e-89	322.00
IUUC-Gmo-039669	Gadus morhua	53.34	0.00e+00	828.00
IUUC-Ggr-039988	Gaeumannomyces graminis	32.17	8.00e-75	275.00
IUUC-Gga-040423	Gallus gallus	74.86	0.00e+00	1772.00
IUUC-Gac-042134	Gasterosteus aculeatus	50.96	0.00e+00	818.00
IUUC-Gma-042929	Glycine max	36.02	1.00e-86	314.00
IUUC-Ggo-044528	Gorilla gorilla	86.32	0.00e+00	2103.00
IUUC-Hsa-046259	Homo sapiens	86.08	0.00e+00	2071.00
IUUC-Hvu-047139	Hordeum vulgare	36.59	1.00e-57	217.00
IUUC-Itr-048621	Ictidomys tridecemlineatus	84.70	0.00e+00	2069.00
IUUC-Kpa-049169	Komagataella pastoris	28.85	3.00e-61	229.00
IUUC-Lch-050471	Latimeria chalumnae	64.25	0.00e+00	1513.00
IUUC-Lpe-050800	Leersia perrieri	31.53	8.00e-87	315.00
IUUC-Loc-052320	Lepisosteus oculatus	48.18	0.00e+00	958.00
IUUC-Lma-053149	Leptosphaeria maculans	32.79	9.00e-81	295.00
IUUC-Laf-053810	Loxodonta africana	82.41	0.00e+00	1922.00
IUUC-Mcc-055574	Macaca mulatta	85.92	0.00e+00	2056.00
IUUC-Meu-055945	Macropus eugenii	63.60	0.00e+00	1098.00
IUUC-Mor-057195	Magnaporthe oryzae	31.44	2.00e-92	334.00
IUUC-Mpo-057488	Magnaporthe poae	36.71	9.00e-77	281.00
IUUC-Mtr-057955	Medicago truncatula	35.31	9.00e-88	318.00
IUUC-Mla-059027	Melampsora laricipopulina	35.64	5.00e-79	288.00
IUUC-Mga-060156	Meleagris gallopavo	74.94	0.00e+00	1783.00
IUUC-Mvi-060398	Microbotryum violaceum	35.45	4.00e-80	293.00
IUUC-Mmr-061113	Microcebus murinus	87.10	0.00e+00	2079.00
IUUC-Mdo-063001	Monodelphis domestica	80.73	0.00e+00	1942.00
IUUC-Mmu-063180	Mus musculus	80.35	0.00e+00	1951.00
IUUC-Mac-065551	Musa acuminata	36.98	3.00e-52	199.00
IUUC-Mpu-066525	Mustela putorius furo	87.82	0.00e+00	2118.00
IUUC-Mlu-067877	Myotis lucifugus	85.83	0.00e+00	2056.00
IUUC-Nfi-068418	Neosartorya fischeri	36.62	1.00e-82	301.00
IUUC-Ncr-068648	Neurospora crassa	31.89	7.00e-87	315.00
IUUC-Nle-069959	Nomascus leucogenys	86.48	0.00e+00	2092.00
IUUC-Opr-070522	Ochotona princeps	81.27	0.00e+00	1154.00
IUUC-Ont-072293	Oreochromis niloticus	49.09	0.00e+00	820.00
IUUC-Oan-073519	Ornithorhynchus anatinus	77.79	0.00e+00	1893.00
IUUC-Ocu-074492	Oryctolagus cuniculus	82.77	0.00e+00	1884.00
IUUC-Oba-075567	Oryza barthii	33.02	1.00e-87	318.00
IUUC-Obr-076332	Oryza brachyantha	37.14	4.00e-86	312.00
IUUC-Ogl-077348	Oryza glaberrima	33.02	1.00e-87	317.00
IUUC-Ogu-078779	Oryza glumaepatula	33.07	2.00e-87	317.00
IUUC-Oin-079738	Oryza indica	30.58	4.00e-76	279.00
IUUC-Olo-080701	Oryza longistaminata	30.53	4.00e-76	279.00
IUUC-Ome-081708	Oryza meridionalis	33.01	4.00e-85	310.00
IUUC-Oni-082251	Oryza nivara	32.92	2.00e-85	310.00
IUUC-Opu-083528	Oryza punctata	32.11	8.00e-80	291.00
IUUC-Oru-084293	Oryza rufipogon	32.43	7.00e-83	302.00
IUUC-Osa-085549	Oryza sativa	33.23	9.00e-88	318.00
IUUC-Ola-086793	Oryzias latipes	47.31	0.00e+00	1022.00
IUUC-Olu-087786	Ostreococcus lucimarinus	29.17	1.00e-61	230.00
IUUC-Oga-089006	Otolemur garnettii	85.77	0.00e+00	2081.00
IUUC-Oar-089597	Ovis aries	85.75	0.00e+00	2052.00
IUUC-Ptr-091520	Pan troglodytes	86.16	0.00e+00	2071.00
IUUC-Pan-092333	Papio anubis	86.54	0.00e+00	2050.00
IUUC-Psi-094004	Pelodiscus sinensis	76.38	0.00e+00	1840.00
IUUC-Pma-094128	Petromyzon marinus	53.05	4.00e-91	328.00
IUUC-Pno-094849	Phaeosphaeria nodorum	33.27	2.00e-73	271.00
IUUC-Ppa-095714	Physcomitrella patens	36.10	2.00e-88	320.00
IUUC-Pfo-096569	Poecilia formosa	47.85	0.00e+00	992.00
IUUC-Pab-097960	Pongo abelii	85.84	0.00e+00	2065.00
IUUC-Pop-098921	Populus trichocarpa	35.97	1.00e-82	301.00
IUUC-Pca-100509	Procavia capensis	67.16	0.00e+00	1135.00
IUUC-Ppe-101730	Prunus persica	32.64	2.00e-115	410.00
IUUC-Pva-102142	Pteropus vampyrus	84.16	0.00e+00	2024.00
IUUC-Pgr-103446	Puccinia graminis	31.48	3.00e-70	259.00
IUUC-Ptt-103849	Puccinia triticina	29.63	8.00e-70	259.00
IUUC-Pte-104128	Pyrenophora teres	29.92	4.00e-81	296.00
IUUC-Pyt-104754	Pyrenophora triticirepentis	30.94	9.00e-79	288.00
IUUC-Rno-104871	Rattus norvegicus	78.14	0.00e+00	1919.00
IUUC-Sce-106236	Saccharomyces cerevisiae	26.05	4.00e-39	156.00
IUUC-Sha-106962	Sarcophilus harrisii	80.14	0.00e+00	1915.00
IUUC-Sja-107691	Schizosaccharomyces japonicus	32.78	3.00e-62	233.00
IUUC-Spo-108170	Schizosaccharomyces pombe	33.54	2.00e-62	233.00
IUUC-Ssl-108668	Sclerotinia sclerotiorum	34.67	5.00e-85	309.00
IUUC-Smo-109554	Selaginella moellendorffii	36.10	6.00e-83	302.00
IUUC-Sit-110479	Setaria italica	42.72	2.00e-70	261.00
IUUC-Sly-111752	Solanum lycopersicum	35.09	4.00e-88	319.00
IUUC-Sar-113304	Sorex araneus	85.18	0.00e+00	2020.00
IUUC-Sbi-114196	Sorghum bicolor	43.05	2.00e-71	263.00
IUUC-Sre-115151	Sporisorium reilianum	34.25	1.00e-86	315.00
IUUC-Tgu-117438	Taeniopygia guttata	74.47	0.00e+00	1756.00
IUUC-Tru-118553	Takifugu rubripes	48.60	0.00e+00	1008.00
IUUC-Tsy-119056	Tarsius syrichta	83.15	0.00e+00	1929.00
IUUC-Tni-119933	Tetraodon nigroviridis	47.31	0.00e+00	787.00
IUUC-Tca-121376	Theobroma cacao	36.48	5.00e-86	312.00
IUUC-Tre-121972	Trichoderma reesei	27.88	3.00e-80	293.00
IUUC-Tvi-122342	Trichoderma virens	34.41	2.00e-70	260.00
IUUC-Tae-123898	Triticum aestivum	33.65	7.00e-88	318.00
IUUC-Tur-126735	Triticum urartu	37.57	9.00e-34	139.00
IUUC-Tme-126999	Tuber melanosporum	32.52	7.00e-80	292.00
IUUC-Tbe-127280	Tupaia belangeri	86.35	2.00e-139	490.00
IUUC-Ttr-129104	Tursiops truncatus	89.33	0.00e+00	2117.00
IUUC-Uma-129562	Ustilago maydis	31.38	3.00e-85	310.00
IUUC-Vda-129862	Verticillium dahliae	33.80	9.00e-81	295.00
IUUC-Vpa-130819	Vicugna pacos	85.02	0.00e+00	1105.00
IUUC-Vvi-131111	Vitis vinifera	35.89	1.00e-83	304.00
IUUC-Xtr-132629	Xenopus tropicalis	60.17	0.00e+00	1377.00
IUUC-Xma-134065	Xiphophorus maculatus	50.00	0.00e+00	808.00
IUUC-Yli-134633	Yarrowia lipolytica	31.69	2.00e-61	230.00
IUUC-Zma-135176	Zea mays	34.00	1.00e-88	321.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence