iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-022316

Ensembl Protein ID

ENSCPOP00000020000.1

UniProt Accession

H0WAI8; H0WAI8_CAVPO

Genbank Protein ID

ENSCPOP00000020000

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02049175

Gene Name

NWD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000024668.1	ENSCPOT00000021800.1	ENSCPOP00000020000.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.80e-28	96.3	1363	1398
UBD/Beta-Prp	2.20e-42	145.2	837	1034

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWDlrtgvl 35
           H +++tc++   s+ l vsGs  g + +WDlr + +
   Q: 1363 HGSPITCVDVshSELLAVSGSQEGRLCLWDLRACEC 1398
           9*********8554777**************98876 PP

UBD/Beta-Prp

   S: 87   vhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllr 173
             tl+g  + v++l++sp+ ++lv+G +d ++ vwd++++ +++ +l gh+g v+cv+v   g l +s+s Dr + lW l +g+  +
   Q: 837  YATLTGCHRGVTALAWSPEEQRLVVGAQDGMVTVWDVQKQRVSY-VLMGHTGEVMCVAVLARGTLAISASRDRSLCLWHLLSGR--E 920
           5688999999*********************************9.*********************************998876..7 PP
   S: 174  tltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvk.svrfspnderlvsgssDgsiriWdlrsgdl 256
           ++t+ + +   s       ++   +v+++  ++v  w+lqt+e v +  g t+n++ + +++    rl++ s+ g +++W + +g+l
   Q: 921  RWTQRDVGLPDSQPfslCVDEVHGVVYAAWGSQVSAWSLQTSELVFRILGDTANPCvCTAVLVSRARLLTLSKSGAVSMWSSATGQL 1007
           887644444444443344455699****************88887777776655542677779999********************9 PP
   S: 257  lktlqlhn...ssvisvavlsfgdnvl 280
            +t +l+    +++++v  ++ +++v+
   Q: 1008 QGTWSLSTtpeETLTCVVPIQQQGRVI 1034
           999999887766666666555555555 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

TICQKHGLPF EAVDLRWGLR NSEAAEQLTV DLCLEELERC QRTSLGPAFV ALVGDQYGPC 60
PVPRRIEEKE WEVLRAQLST RPRDLELLIR CFRRDENSVP PSYVLQAVGN EEATGPDEPT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACCATCTGCC AGAAGCATGG CCTTCCCTTC GAGGTGAGCA CTGTTTTCCA GGCCCGTTCA 60
CTCCCACAGT ACCGAGAGGG CCCCAGGGAG CCCCCAAAGC TCCCCCCCAC TGCTTTTTAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR027417--P-loop_NTPase
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001525	Ailuropoda melanoleuca	67.07	0.00e+00	2002.00
IUUC-Apl-003467	Anas platyrhynchos	53.85	3.00e-71	261.00
IUUC-Ame-011400	Astyanax mexicanus	35.28	0.00e+00	862.00
IUUC-Bta-013223	Bos taurus	65.64	0.00e+00	1722.00
IUUC-Cel-018404	Caenorhabditis elegans	27.97	1.00e-87	318.00
IUUC-Cja-018773	Callithrix jacchus	64.26	0.00e+00	1199.00
IUUC-Cfa-020334	Canis familiaris	66.67	0.00e+00	1993.00
IUUC-Csa-023631	Chlorocebus sabaeus	66.17	0.00e+00	1952.00
IUUC-Cin-025646	Ciona intestinalis	30.77	4.00e-111	395.00
IUUC-Csv-026191	Ciona savignyi	25.67	1.00e-21	97.10
IUUC-Dre-028241	Danio rerio	34.59	0.00e+00	820.00
IUUC-Dno-029990	Dasypus novemcinctus	69.23	8.00e-172	596.00
IUUC-Dor-030869	Dipodomys ordii	59.56	7.00e-147	514.00
IUUC-Ete-033059	Echinops telfairi	64.11	0.00e+00	633.00
IUUC-Eca-033718	Equus caballus	65.40	0.00e+00	1915.00
IUUC-Fca-035748	Felis catus	66.29	0.00e+00	1839.00
IUUC-Gac-041507	Gasterosteus aculeatus	33.93	0.00e+00	629.00
IUUC-Ggo-044551	Gorilla gorilla	63.62	0.00e+00	1868.00
IUUC-Hsa-046787	Homo sapiens	65.66	0.00e+00	1972.00
IUUC-Itr-048104	Ictidomys tridecemlineatus	53.22	0.00e+00	1377.00
IUUC-Lch-049578	Latimeria chalumnae	43.31	0.00e+00	1202.00
IUUC-Loc-052039	Lepisosteus oculatus	39.22	0.00e+00	1067.00
IUUC-Laf-054240	Loxodonta africana	66.88	0.00e+00	2017.00
IUUC-Mcc-054657	Macaca mulatta	60.25	0.00e+00	1675.00
IUUC-Meu-056591	Macropus eugenii	54.48	0.00e+00	962.00
IUUC-Mmr-061577	Microcebus murinus	65.40	0.00e+00	1917.00
IUUC-Mdo-062895	Monodelphis domestica	53.69	0.00e+00	1466.00
IUUC-Mmu-063866	Mus musculus	64.71	0.00e+00	1900.00
IUUC-Mpu-066510	Mustela putorius furo	66.75	0.00e+00	2021.00
IUUC-Mlu-067855	Myotis lucifugus	66.65	0.00e+00	1910.00
IUUC-Nle-069557	Nomascus leucogenys	62.30	0.00e+00	1780.00
IUUC-Opr-071196	Ochotona princeps	60.67	4.00e-157	549.00
IUUC-Ont-072070	Oreochromis niloticus	33.57	0.00e+00	664.00
IUUC-Oan-073437	Ornithorhynchus anatinus	49.39	0.00e+00	1017.00
IUUC-Ocu-074941	Oryctolagus cuniculus	63.87	4.00e-39	154.00
IUUC-Ola-086624	Oryzias latipes	31.88	3.00e-176	612.00
IUUC-Oga-088313	Otolemur garnettii	65.63	0.00e+00	1768.00
IUUC-Oar-090123	Ovis aries	66.04	0.00e+00	1968.00
IUUC-Ptr-090552	Pan troglodytes	64.29	0.00e+00	850.00
IUUC-Psi-093963	Pelodiscus sinensis	47.99	0.00e+00	1335.00
IUUC-Pfo-096197	Poecilia formosa	34.47	0.00e+00	687.00
IUUC-Pab-097755	Pongo abelii	60.50	0.00e+00	689.00
IUUC-Pca-100809	Procavia capensis	61.74	0.00e+00	915.00
IUUC-Pva-102554	Pteropus vampyrus	62.71	0.00e+00	1640.00
IUUC-Rno-105174	Rattus norvegicus	59.32	0.00e+00	1655.00
IUUC-Sha-107304	Sarcophilus harrisii	52.93	0.00e+00	1599.00
IUUC-Sar-113168	Sorex araneus	59.31	0.00e+00	1133.00
IUUC-Tru-118251	Takifugu rubripes	34.65	7.00e-164	571.00
IUUC-Tsy-119276	Tarsius syrichta	64.23	1.00e-95	344.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence