iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000076110.4	ENSDART00000156764.2	ENSDARP00000129001.2
ENSDARG00000076110.4	ENSDART00000111559.3	ENSDARP00000099546.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.60e-15	56.9	1488	1520
UBD/Beta-Prp	7.90e-43	147.7	918	1130

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 6    vtclaf..sdtllvsGsdDgtikvWDlrtgvll 36
           v c  f  +d+++ +Gs D+t+kvWD+++g ll
   Q: 1488 VLCAVFsiNDKYVFTGSLDKTVKVWDVSSGCLL 1520
           6776689899*****************999876 PP

UBD/Beta-Prp

   S: 84   gkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...k 167
           g+  +tl+g ++ v ++ ++ +++ l++Gs+d  i vw l++ q l+ tlsgh++ v ++++ +++n + s +lD+t+r W+l    
   Q: 918  GPLKSTLRGFTKGVKAVVLCSKRKLLLAGSEDGLIIVWSLNNLQPLH-TLSGHKAGVLSLKLTDKTNNCLSTGLDGTLRKWCLisgL 1003
           55667888999999999999999999999999999999999999999.999999999999999999999999999999999997777 PP
   S: 168  tgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW....d 250
           + +++++  + +t+s +++ +++++  ++     ++vk wdl t e + +l++    v+ +  +     +++  s+  + ++     
   Q: 1004 QLFCITDAVSVQTHSPTHIHMNEER-KIIITNPSSQVKAWDLDTAEPLFELTAVIGSVLGIVED----EIACICSEAILCFYdistG 1085
           7788888877899999999999975.66666778999999999999999999999999988776....7777777888888833333 PP
   S: 251  lrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvniwklk 295
           ++++++l  ++  +++++++ +l    ++l++++e     +w+ +
   Q: 1086 TQTSQTLLPYSAGHHNITCCLTLTKHSKILIAFGESRLHSVWSHE 1130
           344445555566669999999999999999999998888888765 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MDVVEMREAL GLEVLRGQSA DSLQPTSRMV RVFISSTHSD MKNERNAFWE KTYSELQTHC 60
QSLGLVFEVV DFKCGMRDIT ASDHLITELC IKEIETCQRI SDGPTFIALI GNQYGHRLVP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGATCTCTG TGGCAGGCGG TGGCTCGTAA ACACCGGGTC TCCCTCGGCC TTCCTGATCT 60
CAGTGGATAA AATGACGGCG CTGAGGAGAA CAAACAACCG AGCTGGAGCG CCCTGCAACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR003593--AAA+_ATPase
IPR025139--DUF4062
IPR027417--P-loop_NTPase
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF13271--DUF4062
PF00400--WD40

SMART

SM00382--AAA
SM00320--WD40

Gene Ontology

GO:0005938--C:cell cortex
GO:0005813--C:centrosome
GO:0000776--C:kinetochore
GO:0005874--C:microtubule
GO:0005875--C:microtubule associated complex
GO:0008017--F:microtubule binding

KEGG

dre:100330908

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001525	Ailuropoda melanoleuca	36.20	0.00e+00	958.00
IUUC-Apl-003467	Anas platyrhynchos	37.34	4.00e-45	174.00
IUUC-Ame-011400	Astyanax mexicanus	59.25	0.00e+00	1866.00
IUUC-Bta-013223	Bos taurus	36.29	0.00e+00	822.00
IUUC-Cel-018404	Caenorhabditis elegans	30.08	4.00e-102	367.00
IUUC-Cja-018773	Callithrix jacchus	36.70	1.00e-164	574.00
IUUC-Cfa-020334	Canis familiaris	36.43	0.00e+00	976.00
IUUC-Cpo-022316	Cavia porcellus	34.35	0.00e+00	783.00
IUUC-Csa-023631	Chlorocebus sabaeus	36.35	0.00e+00	931.00
IUUC-Cin-025646	Ciona intestinalis	34.19	3.00e-106	380.00
IUUC-Dno-029990	Dasypus novemcinctus	35.66	1.00e-70	260.00
IUUC-Dor-030869	Dipodomys ordii	36.47	8.00e-80	292.00
IUUC-Dme-032096	Drosophila melanogaster	22.13	9.00e-32	133.00
IUUC-Ete-033059	Echinops telfairi	31.25	5.00e-68	253.00
IUUC-Eca-033718	Equus caballus	35.46	0.00e+00	914.00
IUUC-Fca-035748	Felis catus	35.75	0.00e+00	887.00
IUUC-Gac-041507	Gasterosteus aculeatus	44.94	0.00e+00	1152.00
IUUC-Ggo-044551	Gorilla gorilla	34.83	0.00e+00	851.00
IUUC-Hsa-046787	Homo sapiens	36.63	0.00e+00	944.00
IUUC-Itr-048104	Ictidomys tridecemlineatus	30.61	1.00e-86	315.00
IUUC-Lch-049578	Latimeria chalumnae	40.67	0.00e+00	1142.00
IUUC-Loc-052039	Lepisosteus oculatus	48.69	0.00e+00	1528.00
IUUC-Laf-054240	Loxodonta africana	36.20	0.00e+00	986.00
IUUC-Mcc-054657	Macaca mulatta	32.72	0.00e+00	713.00
IUUC-Meu-056591	Macropus eugenii	36.19	1.00e-163	571.00
IUUC-Mmr-061577	Microcebus murinus	34.47	0.00e+00	884.00
IUUC-Mdo-062895	Monodelphis domestica	36.93	0.00e+00	906.00
IUUC-Mmu-063866	Mus musculus	35.24	0.00e+00	898.00
IUUC-Mpu-066510	Mustela putorius furo	36.16	0.00e+00	981.00
IUUC-Mlu-067855	Myotis lucifugus	36.25	0.00e+00	917.00
IUUC-Nle-069557	Nomascus leucogenys	36.11	0.00e+00	863.00
IUUC-Opr-071196	Ochotona princeps	33.88	2.00e-64	241.00
IUUC-Ont-072070	Oreochromis niloticus	45.09	0.00e+00	1254.00
IUUC-Oan-073437	Ornithorhynchus anatinus	37.71	0.00e+00	709.00
IUUC-Ocu-074941	Oryctolagus cuniculus	41.53	2.00e-24	105.00
IUUC-Ola-086624	Oryzias latipes	43.79	0.00e+00	1122.00
IUUC-Oga-088313	Otolemur garnettii	35.71	0.00e+00	835.00
IUUC-Oar-090123	Ovis aries	35.54	0.00e+00	951.00
IUUC-Ptr-090552	Pan troglodytes	32.17	3.00e-93	337.00
IUUC-Psi-093963	Pelodiscus sinensis	38.12	0.00e+00	1022.00
IUUC-Pfo-096197	Poecilia formosa	43.36	0.00e+00	1239.00
IUUC-Pab-097755	Pongo abelii	30.35	2.00e-75	276.00
IUUC-Pca-100809	Procavia capensis	33.72	3.00e-124	440.00
IUUC-Pva-102554	Pteropus vampyrus	34.05	0.00e+00	760.00
IUUC-Rno-105174	Rattus norvegicus	32.53	0.00e+00	728.00
IUUC-Sha-107304	Sarcophilus harrisii	37.48	0.00e+00	1045.00
IUUC-Sar-113168	Sorex araneus	38.13	6.00e-113	402.00
IUUC-Tru-118251	Takifugu rubripes	42.20	0.00e+00	993.00
IUUC-Tsy-119276	Tarsius syrichta	32.08	3.00e-32	134.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence