iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-035748

Ensembl Protein ID

ENSFCAP00000012218.3

UniProt Accession

M3WIC6; M3WIC6_FELCA

Genbank Protein ID

ENSFCAP00000012218

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02176225

Gene Name

NWD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000013175.3	ENSFCAT00000013179.3	ENSFCAP00000012218.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.30e-25	87.6	865	897
UBD/Beta-Prp	3.40e-45	154.5	859	1033

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
           H++ +t++a+  + +llv+G+ Dgt+ vWD+ ++
   Q: 865  HKG-ITAMAWsVEeRLLVVGTQDGTVAVWDTEEH 897
           555.9*****955699**************8665 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee. 131
           ++l g+ +++ta+ +s ++ +lv g +D+t+ vwd +  + +h   gh+ +v+ ++++++g   +s+s+d t+r+w+l tgq+  + 
   Q: 859  ATLTGCHKGITAMAWSVEERLLVVGTQDGTVAVWDTEEHQVIHMHMGHTGEVRYVKVFAKGTLALSASKDHTLRLWNLLTGQEKFTi 945
           688999999999999999999999999999999999999999999999999999999999999999999999999999999999888 PP
   S: 132  ....tlsghdgvvncvvvhpdg..nllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtg 212
                +++ +  ++++++++++   +l+sGs   +v  W l+t++l+ +  g+  d      +  ++  l+++s+ g   lw+  tg
   Q: 946  wdggSKDPMQPETWSLHLDETKkvVYLASGS---KVSAWHLETAELVFQILGDPSDCWVYAGVLASRATLLTVSQGGVAGLWSSATG 1029
           8888777777788999999988555666666...58899999999999999977777777778888899999999999999999888 PP
   S: 213  ecvr 216
           +   
   Q: 1030 KPQG 1033
           8655 PP

Organism

Felis catus

Protein Sequence
(Fasta)

REKPYRAPPT PKCRFCQKHG LMFEVVDLRW GIRNTEATEH MTTELCLEEL DRCRKTSTGP 60
AFVALLGDQY GPCPVPTLIE EKEWEALRAQ LTSKPRDLEL VAQHFRRDEN AVPPTYLLQA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGAGAGAAGC CCTACAGAGC ACCGCCTACC CCGAAGTGCA GAACTTCTGC CAAAAGCACG 60
GTCTGATGTT TGAGGTAACT GCCCCCTCCC TGCCTCAGTT TCCCCTGCCC TGAAATTAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR027417--P-loop_NTPase
IPR011044--Quino_amine_DH_bsu
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0071011--C:precatalytic spliceosome
GO:0005682--C:U5 snRNP
GO:0008380--P:RNA splicing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001525	Ailuropoda melanoleuca	90.16	0.00e+00	2543.00
IUUC-Apl-003467	Anas platyrhynchos	59.46	2.00e-65	241.00
IUUC-Ame-011400	Astyanax mexicanus	36.41	0.00e+00	865.00
IUUC-Bta-013223	Bos taurus	84.63	0.00e+00	2067.00
IUUC-Cel-018404	Caenorhabditis elegans	28.19	7.00e-100	359.00
IUUC-Cja-018773	Callithrix jacchus	79.55	0.00e+00	1296.00
IUUC-Cfa-020334	Canis familiaris	91.15	0.00e+00	2600.00
IUUC-Cpo-022316	Cavia porcellus	66.29	0.00e+00	1743.00
IUUC-Csa-023631	Chlorocebus sabaeus	82.23	0.00e+00	2329.00
IUUC-Cin-025646	Ciona intestinalis	31.79	8.00e-126	444.00
IUUC-Csv-026191	Ciona savignyi	26.15	4.00e-24	105.00
IUUC-Dre-028241	Danio rerio	35.75	0.00e+00	839.00
IUUC-Dno-029990	Dasypus novemcinctus	78.96	1.00e-138	486.00
IUUC-Dor-030869	Dipodomys ordii	62.02	6.00e-179	621.00
IUUC-Ete-033059	Echinops telfairi	82.24	0.00e+00	833.00
IUUC-Eca-033718	Equus caballus	81.42	0.00e+00	2302.00
IUUC-Gac-041507	Gasterosteus aculeatus	36.34	0.00e+00	749.00
IUUC-Ggo-044551	Gorilla gorilla	80.22	0.00e+00	2276.00
IUUC-Hsa-046787	Homo sapiens	81.43	0.00e+00	2317.00
IUUC-Itr-048104	Ictidomys tridecemlineatus	62.33	0.00e+00	1566.00
IUUC-Lch-049578	Latimeria chalumnae	48.20	0.00e+00	1326.00
IUUC-Loc-052039	Lepisosteus oculatus	41.54	0.00e+00	1117.00
IUUC-Laf-054240	Loxodonta africana	82.66	0.00e+00	2393.00
IUUC-Mcc-054657	Macaca mulatta	74.46	0.00e+00	1969.00
IUUC-Meu-056591	Macropus eugenii	62.68	0.00e+00	1146.00
IUUC-Mmr-061577	Microcebus murinus	78.30	0.00e+00	2192.00
IUUC-Mdo-062895	Monodelphis domestica	61.85	0.00e+00	1784.00
IUUC-Mmu-063866	Mus musculus	77.11	0.00e+00	2132.00
IUUC-Mpu-066510	Mustela putorius furo	88.81	0.00e+00	2551.00
IUUC-Mlu-067855	Myotis lucifugus	85.13	0.00e+00	2329.00
IUUC-Nle-069557	Nomascus leucogenys	76.68	0.00e+00	2116.00
IUUC-Opr-071196	Ochotona princeps	63.81	0.00e+00	647.00
IUUC-Ont-072070	Oreochromis niloticus	36.27	0.00e+00	733.00
IUUC-Oan-073437	Ornithorhynchus anatinus	57.60	0.00e+00	1271.00
IUUC-Ocu-074941	Oryctolagus cuniculus	85.45	3.00e-53	201.00
IUUC-Ola-086624	Oryzias latipes	34.08	0.00e+00	636.00
IUUC-Oga-088313	Otolemur garnettii	82.69	0.00e+00	2330.00
IUUC-Oar-090123	Ovis aries	84.42	0.00e+00	2372.00
IUUC-Ptr-090552	Pan troglodytes	79.77	0.00e+00	836.00
IUUC-Psi-093963	Pelodiscus sinensis	54.01	0.00e+00	1566.00
IUUC-Pfo-096197	Poecilia formosa	34.79	0.00e+00	732.00
IUUC-Pab-097755	Pongo abelii	78.57	0.00e+00	887.00
IUUC-Pca-100809	Procavia capensis	78.73	0.00e+00	1214.00
IUUC-Pva-102554	Pteropus vampyrus	82.25	0.00e+00	2283.00
IUUC-Rno-105174	Rattus norvegicus	69.38	0.00e+00	1843.00
IUUC-Sha-107304	Sarcophilus harrisii	62.11	0.00e+00	1821.00
IUUC-Sar-113168	Sorex araneus	66.50	0.00e+00	1394.00
IUUC-Tru-118251	Takifugu rubripes	36.47	0.00e+00	665.00
IUUC-Tsy-119276	Tarsius syrichta	77.54	1.00e-116	414.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence