iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066510

Ensembl Protein ID

ENSMPUP00000015910.1

UniProt Accession

M3YX50; M3YX50_MUSPF

Genbank Protein ID

ENSMPUP00000015910

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01051476

Gene Name

NWD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000016016.1	ENSMPUT00000016153.1	ENSMPUP00000015910.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.90e-23	81.0	946	980
UBD/Beta-Prp	2.10e-51	174.9	898	1072

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtcla.f.sdtllvsGsdDgtikvWDlrtg 33
           gHt++v  ++ f  +tl +s+s D+t+++WDl +g
   Q: 946  GHTGEVKYVKvFaKGTLALSASKDHTLRLWDLLSG 980
           8********9678669***************9776 PP

UBD/Beta-Prp

   S: 86   cvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkll 172
              tl+g  + ++++++s +   lv+G++d ++ vwd+e++q+++ +l+gh+g v +v+v  +g l  s+s+D t+rlWdl +g+  
   Q: 898  LRATLTGCHKGITAMAWSLEERLLVVGTQDGIVAVWDMEEQQVIH-ILTGHTGEVKYVKVFAKGTLALSASKDHTLRLWDLLSGQEK 983
           56789999999**********************************.***********************************999887 PP
   S: 173  rtl.....tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght.dnvksvrfspnderlvsgssDgsiriWdlrs 253
            t      +   ++ + sl +++  k +v+ +  +++  w+l+t e v +  gh  d   + r++     l+++s+ g++++W + +
   Q: 984  FTIwdrgsRDPTEPEIWSLHVEE-AKKVVYLASGSKISAWNLETAELVFRILGHVsDRWMCTRVLASRAMLLTVSEAGVVSLWSSAT 1069
           77779887555667777777777.689****************999999999987355567888999****************8776 PP
   S: 254  gdl 256
           g+l
   Q: 1070 GTL 1072
           654 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MCRARRPWRT KSLYSWDSCP CGKTSNKETR RNISAGDMDA EREALQSTAF PEVQTFCQKH 60
GLMFEVVDLR WGIRSSEATD HMTTELCLEE LDRCRKTSIG PAFVALLGDQ YGPCPVPTLI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTGCCGAG CACGCCGACC TTGGCGGACA AAGTCCTTGT ACTCATGGGA CTCATGTCCT 60
TGTGGAAAGA CAAGCAATAA AGAAACAAGA AGAAACATAT CAGCTGGTGG TGAGTACCAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR025139--DUF4062
IPR027417--P-loop_NTPase
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF13271--DUF4062
PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001525	Ailuropoda melanoleuca	92.14	0.00e+00	2885.00
IUUC-Apl-003467	Anas platyrhynchos	58.80	6.00e-82	296.00
IUUC-Ame-011400	Astyanax mexicanus	36.27	0.00e+00	979.00
IUUC-Bta-013223	Bos taurus	85.35	0.00e+00	2312.00
IUUC-Cel-018404	Caenorhabditis elegans	28.76	1.00e-106	382.00
IUUC-Cja-018773	Callithrix jacchus	81.22	0.00e+00	1535.00
IUUC-Cfa-020334	Canis familiaris	92.04	0.00e+00	2879.00
IUUC-Cpo-022316	Cavia porcellus	66.75	0.00e+00	1946.00
IUUC-Csa-023631	Chlorocebus sabaeus	82.56	0.00e+00	2539.00
IUUC-Cin-025646	Ciona intestinalis	32.20	2.00e-130	460.00
IUUC-Csv-026191	Ciona savignyi	26.45	2.00e-26	113.00
IUUC-Dre-028241	Danio rerio	36.26	0.00e+00	957.00
IUUC-Dno-029990	Dasypus novemcinctus	79.28	0.00e+00	707.00
IUUC-Dor-030869	Dipodomys ordii	62.75	2.00e-180	626.00
IUUC-Ete-033059	Echinops telfairi	83.98	0.00e+00	845.00
IUUC-Eca-033718	Equus caballus	81.11	0.00e+00	2528.00
IUUC-Fca-035748	Felis catus	88.81	0.00e+00	2582.00
IUUC-Gac-041507	Gasterosteus aculeatus	35.34	0.00e+00	757.00
IUUC-Ggo-044551	Gorilla gorilla	79.46	0.00e+00	2425.00
IUUC-Hsa-046787	Homo sapiens	82.14	0.00e+00	2539.00
IUUC-Itr-048104	Ictidomys tridecemlineatus	64.52	0.00e+00	1824.00
IUUC-Lch-049578	Latimeria chalumnae	47.55	0.00e+00	1433.00
IUUC-Loc-052039	Lepisosteus oculatus	41.39	0.00e+00	1231.00
IUUC-Laf-054240	Loxodonta africana	82.89	0.00e+00	2650.00
IUUC-Mcc-054657	Macaca mulatta	74.95	0.00e+00	2191.00
IUUC-Meu-056591	Macropus eugenii	62.74	0.00e+00	1149.00
IUUC-Mmr-061577	Microcebus murinus	79.66	0.00e+00	2452.00
IUUC-Mdo-062895	Monodelphis domestica	62.04	0.00e+00	1795.00
IUUC-Mmu-063866	Mus musculus	77.19	0.00e+00	2378.00
IUUC-Mlu-067855	Myotis lucifugus	84.86	0.00e+00	2589.00
IUUC-Nle-069557	Nomascus leucogenys	77.61	0.00e+00	2318.00
IUUC-Opr-071196	Ochotona princeps	65.21	0.00e+00	653.00
IUUC-Ont-072070	Oreochromis niloticus	35.86	0.00e+00	818.00
IUUC-Oan-073437	Ornithorhynchus anatinus	57.45	0.00e+00	1265.00
IUUC-Ocu-074941	Oryctolagus cuniculus	78.33	8.00e-54	202.00
IUUC-Ola-086624	Oryzias latipes	33.78	0.00e+00	710.00
IUUC-Oga-088313	Otolemur garnettii	83.25	0.00e+00	2337.00
IUUC-Oar-090123	Ovis aries	84.92	0.00e+00	2654.00
IUUC-Ptr-090552	Pan troglodytes	81.50	0.00e+00	1076.00
IUUC-Psi-093963	Pelodiscus sinensis	54.51	0.00e+00	1627.00
IUUC-Pfo-096197	Poecilia formosa	34.65	0.00e+00	845.00
IUUC-Pab-097755	Pongo abelii	80.54	0.00e+00	905.00
IUUC-Pca-100809	Procavia capensis	78.86	0.00e+00	1221.00
IUUC-Pva-102554	Pteropus vampyrus	82.73	0.00e+00	2279.00
IUUC-Rno-105174	Rattus norvegicus	70.11	0.00e+00	2082.00
IUUC-Sha-107304	Sarcophilus harrisii	61.57	0.00e+00	1985.00
IUUC-Sar-113168	Sorex araneus	66.58	0.00e+00	1391.00
IUUC-Tru-118251	Takifugu rubripes	36.07	0.00e+00	684.00
IUUC-Tsy-119276	Tarsius syrichta	78.99	6.00e-120	426.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence